KEGG   Manis javanica (Malayan pangolin): 108389003
Entry
108389003         CDS       T06054                                 
Symbol
GSK3B
Name
(RefSeq) glycogen synthase kinase-3 beta isoform X5
  KO
K03083  glycogen synthase kinase 3 beta [EC:2.7.11.26]
Organism
mjv  Manis javanica (Malayan pangolin)
Pathway
mjv01521  EGFR tyrosine kinase inhibitor resistance
mjv04012  ErbB signaling pathway
mjv04062  Chemokine signaling pathway
mjv04110  Cell cycle
mjv04150  mTOR signaling pathway
mjv04151  PI3K-Akt signaling pathway
mjv04310  Wnt signaling pathway
mjv04340  Hedgehog signaling pathway
mjv04360  Axon guidance
mjv04390  Hippo signaling pathway
mjv04510  Focal adhesion
mjv04550  Signaling pathways regulating pluripotency of stem cells
mjv04657  IL-17 signaling pathway
mjv04660  T cell receptor signaling pathway
mjv04662  B cell receptor signaling pathway
mjv04722  Neurotrophin signaling pathway
mjv04728  Dopaminergic synapse
mjv04910  Insulin signaling pathway
mjv04916  Melanogenesis
mjv04917  Prolactin signaling pathway
mjv04919  Thyroid hormone signaling pathway
mjv04931  Insulin resistance
mjv04932  Non-alcoholic fatty liver disease
mjv04934  Cushing syndrome
mjv04935  Growth hormone synthesis, secretion and action
mjv04936  Alcoholic liver disease
mjv05010  Alzheimer disease
mjv05020  Prion disease
mjv05022  Pathways of neurodegeneration - multiple diseases
mjv05135  Yersinia infection
mjv05160  Hepatitis C
mjv05162  Measles
mjv05163  Human cytomegalovirus infection
mjv05165  Human papillomavirus infection
mjv05167  Kaposi sarcoma-associated herpesvirus infection
mjv05200  Pathways in cancer
mjv05210  Colorectal cancer
mjv05213  Endometrial cancer
mjv05215  Prostate cancer
mjv05217  Basal cell carcinoma
mjv05224  Breast cancer
mjv05225  Hepatocellular carcinoma
mjv05226  Gastric cancer
mjv05415  Diabetic cardiomyopathy
mjv05417  Lipid and atherosclerosis
Brite
KEGG Orthology (KO) [BR:mjv00001]
 09130 Environmental Information Processing
  09132 Signal transduction
   04012 ErbB signaling pathway
    108389003 (GSK3B)
   04310 Wnt signaling pathway
    108389003 (GSK3B)
   04340 Hedgehog signaling pathway
    108389003 (GSK3B)
   04390 Hippo signaling pathway
    108389003 (GSK3B)
   04151 PI3K-Akt signaling pathway
    108389003 (GSK3B)
   04150 mTOR signaling pathway
    108389003 (GSK3B)
 09140 Cellular Processes
  09143 Cell growth and death
   04110 Cell cycle
    108389003 (GSK3B)
  09144 Cellular community - eukaryotes
   04510 Focal adhesion
    108389003 (GSK3B)
   04550 Signaling pathways regulating pluripotency of stem cells
    108389003 (GSK3B)
 09150 Organismal Systems
  09151 Immune system
   04660 T cell receptor signaling pathway
    108389003 (GSK3B)
   04657 IL-17 signaling pathway
    108389003 (GSK3B)
   04662 B cell receptor signaling pathway
    108389003 (GSK3B)
   04062 Chemokine signaling pathway
    108389003 (GSK3B)
  09152 Endocrine system
   04910 Insulin signaling pathway
    108389003 (GSK3B)
   04917 Prolactin signaling pathway
    108389003 (GSK3B)
   04935 Growth hormone synthesis, secretion and action
    108389003 (GSK3B)
   04919 Thyroid hormone signaling pathway
    108389003 (GSK3B)
   04916 Melanogenesis
    108389003 (GSK3B)
  09156 Nervous system
   04728 Dopaminergic synapse
    108389003 (GSK3B)
   04722 Neurotrophin signaling pathway
    108389003 (GSK3B)
  09158 Development and regeneration
   04360 Axon guidance
    108389003 (GSK3B)
 09160 Human Diseases
  09161 Cancer: overview
   05200 Pathways in cancer
    108389003 (GSK3B)
  09162 Cancer: specific types
   05210 Colorectal cancer
    108389003 (GSK3B)
   05225 Hepatocellular carcinoma
    108389003 (GSK3B)
   05226 Gastric cancer
    108389003 (GSK3B)
   05217 Basal cell carcinoma
    108389003 (GSK3B)
   05215 Prostate cancer
    108389003 (GSK3B)
   05213 Endometrial cancer
    108389003 (GSK3B)
   05224 Breast cancer
    108389003 (GSK3B)
  09172 Infectious disease: viral
   05160 Hepatitis C
    108389003 (GSK3B)
   05162 Measles
    108389003 (GSK3B)
   05163 Human cytomegalovirus infection
    108389003 (GSK3B)
   05167 Kaposi sarcoma-associated herpesvirus infection
    108389003 (GSK3B)
   05165 Human papillomavirus infection
    108389003 (GSK3B)
  09171 Infectious disease: bacterial
   05135 Yersinia infection
    108389003 (GSK3B)
  09164 Neurodegenerative disease
   05010 Alzheimer disease
    108389003 (GSK3B)
   05020 Prion disease
    108389003 (GSK3B)
   05022 Pathways of neurodegeneration - multiple diseases
    108389003 (GSK3B)
  09166 Cardiovascular disease
   05417 Lipid and atherosclerosis
    108389003 (GSK3B)
   05415 Diabetic cardiomyopathy
    108389003 (GSK3B)
  09167 Endocrine and metabolic disease
   04936 Alcoholic liver disease
    108389003 (GSK3B)
   04932 Non-alcoholic fatty liver disease
    108389003 (GSK3B)
   04931 Insulin resistance
    108389003 (GSK3B)
   04934 Cushing syndrome
    108389003 (GSK3B)
  09176 Drug resistance: antineoplastic
   01521 EGFR tyrosine kinase inhibitor resistance
    108389003 (GSK3B)
 09180 Brite Hierarchies
  09181 Protein families: metabolism
   01001 Protein kinases [BR:mjv01001]
    108389003 (GSK3B)
  09182 Protein families: genetic information processing
   03036 Chromosome and associated proteins [BR:mjv03036]
    108389003 (GSK3B)
Enzymes [BR:mjv01000]
 2. Transferases
  2.7  Transferring phosphorus-containing groups
   2.7.11  Protein-serine/threonine kinases
    2.7.11.26  tau-protein kinase
     108389003 (GSK3B)
Protein kinases [BR:mjv01001]
 Serine/threonine kinases: CMGC group
  GSK family [OT]
   108389003 (GSK3B)
Chromosome and associated proteins [BR:mjv03036]
 Eukaryotic type
  Centrosome formation proteins
   Kinases and associated factors
    108389003 (GSK3B)
SSDB
Motif
Pfam: Pkinase PK_Tyr_Ser-Thr ABC1 Kinase-like Kdo APH Choline_kinase
Other DBs
NCBI-GeneID: 108389003
NCBI-ProteinID: XP_017503054
Position
Unknown
AA seq 410 aa
MQPEETGDKDGSKVTTVVATPGQGPDRPQEVSYTDTKVIGNGSFGVVYQAKLCDSGELVA
IKKVLQDKRFKNRELQIMRKLDHCNIVRLRYFFYSSGEKKDEVYLNLVLDYVPETVYRVA
RHYSRAKQTLPVIYVKLYMYQLFRSLAYIHSFGICHRDIKPQNLLLDPDTAVLKLCDFGS
AKQLVRGEPNVSYICSRYYRAPELIFGATDYTSSIDVWSAGCVLAELLLGQPIFPGDSGV
DQLVEIIKVLGTPTREQIREMNPNYTEFKFPQIKAHPWTKDSSGTGHFTSGVRVFRPRTP
PEAIALCSRLLEYTPTARLTPLEACAHSFFDELRDPNVKLPNGRDTPALFNFTTQELSSN
PPLATILIPPHARIQAAASTPTNATAASDANAGDRGQTNNAASASASNST
NT seq 1233 nt   +upstreamnt  +downstreamnt
atgcaacctgaggagacaggagacaaagatggcagcaaggtgaccacagtagtggcaact
cctgggcagggtccagacaggccgcaagaagtcagctatacagacactaaagtgattgga
aatgggtcatttggcgtggtatatcaagccaaactttgtgattcaggagaactggttgcc
atcaagaaagtattgcaggacaaaagatttaagaaccgagagctccaaatcatgagaaag
ctagatcactgtaacatagtccgattgcgttatttcttctactcaagcggtgagaagaaa
gatgaggtctatcttaatctggtgctggactatgtcccagaaacagtatacagggttgcc
agacactacagtcgagccaaacagacgctccctgtgatctatgtcaagttgtatatgtat
cagctgtttcgaagtttagcctatatccattcctttggaatctgccatcgggatattaaa
ccacagaacctcttgttggatcccgatacagcggtcttaaaactctgtgactttggaagt
gcaaagcagctggtccgaggagaacccaatgtttcgtatatctgttctcggtactatagg
gcgccggagttgatctttggagccactgattatacctctagtatagatgtatggtctgca
ggctgtgtgttggctgaactgttgctagggcaaccaatatttccaggggacagtggtgta
gatcagttggtggaaataatcaaggtcctggggacaccaacaagggagcaaattagagaa
atgaatccaaactacacagaattcaaattccctcaaattaaggcacatccctggactaag
gattcgtcaggaacaggacatttcacctcaggagtgcgggtcttccgaccgcgaactcca
ccggaggcaattgcactgtgtagtcgtctgctggaatatacaccaactgcccggttgaca
ccactggaagcttgtgcacattcattttttgatgaattacgggacccaaatgtcaaacta
ccaaatgggcgagacacacctgcactcttcaacttcaccactcaagagctgtcaagtaat
ccacctctagctactatccttattcctcctcatgctcggatccaagcagctgcttccacc
cctacaaatgccacagcagcctcagatgctaatgctggagaccgtgggcagaccaataac
gccgcttctgcatcagcttccaactctacctga

  All links  
Ontology (4)   
   KEGG BRITE (4)   
Pathway (45)   
   KEGG PATHWAY (45)   
Chemical reaction (1)   
   KEGG ENZYME (1)   
Genome (1)   
   KEGG GENOME (1)   
Gene (3)   
   KEGG ORTHOLOGY (1)   
   NCBI-PROTEINID (1)   
   NCBI-Gene (1)   
Protein sequence (5)   
   RefSeq(pep) (5)   
DNA sequence (5)   
   RefSeq(nuc) (5)   
Protein domain (7)   
   Pfam (7)   
All databases (71)   

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