KEGG   Manis javanica (Malayan pangolin): 108395486
Entry
108395486         CDS       T06054                                 
Symbol
DNMT1
Name
(RefSeq) DNA (cytosine-5)-methyltransferase 1 isoform X1
  KO
K00558  DNA (cytosine-5)-methyltransferase 1 [EC:2.1.1.37]
Organism
mjv  Manis javanica (Malayan pangolin)
Pathway
mjv00270  Cysteine and methionine metabolism
mjv01100  Metabolic pathways
mjv05206  MicroRNAs in cancer
Module
mjv_M00035  Methionine degradation
Brite
KEGG Orthology (KO) [BR:mjv00001]
 09100 Metabolism
  09105 Amino acid metabolism
   00270 Cysteine and methionine metabolism
    108395486 (DNMT1)
 09160 Human Diseases
  09161 Cancer: overview
   05206 MicroRNAs in cancer
    108395486 (DNMT1)
 09180 Brite Hierarchies
  09182 Protein families: genetic information processing
   03000 Transcription factors [BR:mjv03000]
    108395486 (DNMT1)
   03032 DNA replication proteins [BR:mjv03032]
    108395486 (DNMT1)
   03036 Chromosome and associated proteins [BR:mjv03036]
    108395486 (DNMT1)
  09183 Protein families: signaling and cellular processes
   02048 Prokaryotic defense system [BR:mjv02048]
    108395486 (DNMT1)
Enzymes [BR:mjv01000]
 2. Transferases
  2.1  Transferring one-carbon groups
   2.1.1  Methyltransferases
    2.1.1.37  DNA (cytosine-5-)-methyltransferase
     108395486 (DNMT1)
Transcription factors [BR:mjv03000]
 Eukaryotic type
  Zinc finger
   CXXC CpG-binding proteins
    108395486 (DNMT1)
DNA replication proteins [BR:mjv03032]
 Eukaryotic type
  DNA Replication Termination Factors
   DNA methylation enzymes
    108395486 (DNMT1)
Chromosome and associated proteins [BR:mjv03036]
 Eukaryotic type
  Heterochromatin formation proteins
   Other heterochromatin formation proteins
    108395486 (DNMT1)
Prokaryotic defense system [BR:mjv02048]
 Restriction and modification system (R-M system)
  Type II R-M system
   DNA methyltransferases
    108395486 (DNMT1)
SSDB
Motif
Pfam: BAH DNA_methylase DNMT1-RFD DMAP_binding zf-CXXC HTH_12
Other DBs
NCBI-GeneID: 108395486
NCBI-ProteinID: XP_017513307
Position
Unknown
AA seq 1657 aa
MVRPAFPRAQAGMVRAASAHRPSPSVSARKARAACAAASSAAASEMPARTAPARVPTLSS
RAISLPDDVRRRLKDLERDSLTEKECVKEKLNLLHEFLQTEIKNQLCDLETKLHKEELSE
EGYLAKVKSLLNKDLSLENGAHAFSREVNGCLENGSQTSGEDRRVGMAEENKSPKPVSKL
CVPRRSKSDSEATSEVSSSPRITRQTARQTTITSHFARGPAKRKPEEEPDRVKPDDSVNE
EEKDQEEKRRRVTPGEPVSRPLPAAELERVKPGPYTEEEEDRDEKEEKRLRSQTKELTPI
QKEELDREARPGVQTDMDEGDEKDEKRYRSQPKDLAAKRRPEEKEAERVKPQVSDEKDED
EKEEKRRKTTSKELTEKKMARTKTVMSSKTHPPRCVQCGQYLDDPELKYEQHPADAVDEP
QLLTNERLSIFDANESGFESYEALPQHKLTCFSVYCKRGHLCPIDTGLIEKNVELFFSGS
AKPIYDDDPSLEGGVNGKNLGPINEWWITGFDGGEKALIGFSTSFAEYILMDPNPEYAPL
FSVMQEKIYISKIVVEFLQGNPDSTYEDLINKIETTVPPSVLNLNRFTEDSLLRHAQFVV
EQVESYDEAGDSDEQPIFLTPCMRDLIKLAGVTLGRRRAERRQTIGHSAREKDKGPTKAT
TTKLVYQIFDTFFAEQIEKDDREDKENAFKRRRCGVCEVCQQPECGKCKACKDMVKFGGT
GRSKQACQERRCPNMAMKEADDDEEVDDNIPEMPSPKKMHQGKKKKQNKNRISWIGEAVR
TDGKKSYYKKVCIDLETLEVGDCVSVIPDDSSKPLYLARVTALWEDSSNGQMFHAHWFCA
GTDTVLGATSDPLELFLVDECEDMQLSYIHSKVKVVYRAPSENWALEGGMDPEALKAEDD
GKTYFYQLWYDQDYARFESPPKTQATEDNKYKFCASCARLVEMRQKEIPRVMEQLEDLDG
RVLYSSATKDGVQYRVGSGVYLLPEAFTFNIKLSSPVKRPRKEPVDEDLYPEHYRKYSDY
IKGSNLDAPEPYRIGRIKEIFCSKKSNGRPNETDIKIKLNKFYRPENTHKSTPASYHADI
NLLYWSDEEAVVDFKAVQGRCTVEYGEDLPECLQDFSAGGPDRFYFLEAYNAKSKTFEDP
PNHARSPGNKGKGKGKGKGRAKAQTCEPSEPEAEIKLPKLRTLDVFSGCGGLSEGFHQAG
ISETLWAIEMWDPAAQAFRLNNPGSTVFTEDCNVLLKLVMAGEATNSRGQKLPQKGDVEM
LCGGPPCQGFSGMNRFNSRTYSKFKNSLVVSFLSYCDYYRPRYFLLENVRNFVSFKRSMV
LKLTLRCLVRMGYQCTFGVLQAGQYGVAQTRRRAIILAAAPGEKLPLFPEPLHVFAPRAC
QLSVVVDDKKFVSNITRLSSGPFRTITVRDTMSDLPEVRNGASALEISYNGEPQSWFQRQ
LRGSQYQPILRDHICKDMSALVAARMRHIPLAPGSDWRDLPNIEVRLSDGTMARKLRYTY
HDRKNGCSCTGALRGVCSCVEAGKACDPAARQFNTLIPWCLPHTGNRHNHWAGLYGRLEW
DGFFSTTVTNPEPMGKQGRVLHPEQHRVVSVRECARSQGFPDTYRLFGNILDKHRQVGNA
VPPPLAKAIGLEIKCCMLAKARESASVKIKEEKTTED
NT seq 4974 nt   +upstreamnt  +downstreamnt
atggtacgtcccgccttcccccgcgcccaggctgggatggtgcgcgccgcctccgctcac
cgcccctccccgtcggtttccgcgcgaaaagccagggccgcctgtgctgccgcctcctct
gctgcagcttccgaaatgcctgcccgcactgctccggcccgcgtgcccacgctgtcctcc
cgggccatctcactgcccgacgatgtccgtaggcggctcaaagatttggaaagagatagc
ttaacggaaaaggaatgtgtgaaggagaaactgaatctcttgcatgagtttctgcaaaca
gaaataaagaaccaattatgtgacttggaaaccaaattacataaagaagaattatcggag
gagggctacctggctaaagtcaaatcccttttaaataaagatttgtccttggagaacgga
gctcatgctttcagccgggaagtgaatggatgtctagaaaacgggagccagacaagtggt
gaggaccgcagagtgggaatggcagaggaaaacaaatcccccaaacccgtttccaaactt
tgcgtgcccagaagaagcaagtcggacagcgaggcaacatccgaagtctcgtctagcccc
aggattaccaggcagactgccaggcagaccacaatcacatctcacttcgcgaggggtcct
gccaaacggaaaccagaggaggagcctgacagggtgaaaccagatgactctgtcaatgaa
gaagaaaaagaccaggaggaaaagagacgtcgagtcacgcctggagaaccagtttctaga
ccgctccctgctgcagaactggaaagagtgaaaccaggaccatacacagaggaagaggaa
gacagagatgagaaagaagaaaagaggctcagaagtcaaaccaaagaattaacacctata
cagaaggaggagctggacagggaggcgagaccaggtgttcagactgacatggatgaagga
gacgagaaagatgaaaagaggtacagaagtcaacccaaagatctagctgccaaacggaga
cctgaagaaaaggaagctgaaagagtaaaaccacaagtttctgatgaaaaagatgaggat
gaaaaggaggagaagagacgcaaaactacatccaaagaactaactgagaaaaaaatggct
cgaaccaaaacagtaatgtcctctaagacccacccgccacggtgtgttcagtgcggacag
tacctggacgaccctgagctcaagtacgagcagcaccccgccgacgctgtggatgagcca
cagctattgacaaacgagagactgtccatcttcgatgccaatgagtctggcttcgagagc
tacgaggctctgccgcagcacaaactgacatgcttcagtgtgtactgtaagcgtggtcac
ctgtgcccgatcgacaccggcctcatcgagaagaatgttgagctcttcttttctggttcc
gcaaaaccgatatatgatgacgatccgtcccttgaaggtggtgttaatggcaaaaacctt
ggccccataaatgagtggtggatcactggctttgacggaggggaaaaggcactcattggc
ttcagcacctcctttgccgagtacatcctaatggatcccaacccggagtacgcgccgctc
ttcagtgtgatgcaggagaagatctacatcagtaaaatcgtagtcgagttcctgcagggc
aaccctgactcaacctatgaggacctgatcaataagatagagaccactgtgcccccttct
gtgctcaacctgaaccggttcacagaggactccctcctccggcacgcccagtttgtggtg
gaacaagtcgagagctacgacgaggcgggggacagtgatgagcagcccatcttcctgacg
ccctgcatgagagacctcatcaagttggctggtgtcacactgggaaggaggcgagcagaa
agacgccagaccatcgggcactctgccagagagaaggacaaaggccccacaaaagccacc
accaccaagctggtctaccagatctttgacactttcttcgcagagcagattgaaaaggat
gacagggaagataaagagaacgcctttaaacgccggcggtgtggcgtctgtgaggtctgt
caacaaccggagtgtgggaagtgtaaagcttgtaaggatatggttaagtttggtggtacc
ggacggagcaaacaggcctgccaggaaaggaggtgtcccaacatggccatgaaggaggca
gacgatgacgaagaagtcgatgacaacatcccagagatgccatcacccaaaaaaatgcat
caagggaagaagaagaagcagaacaagaatcggatctcttggattggggaagccgtcagg
actgacgggaagaagagttactataagaaggtttgcattgacttggaaaccctggaagtg
ggggactgtgtctctgtcattccagatgattcctcaaagccgctgtatctagcaagggtc
acggcgttgtgggaggacagcagcaacggccagatgtttcacgcccactggttctgtgct
gggacagacacagttctcggggccacgtcagaccccctggagctgttcctggtagacgaa
tgtgaggacatgcagctgtcttacattcacagtaaggtcaaggtcgtctacagagctcca
tcagagaactgggccttggagggaggcatggatccggaggccctgaaggcggaggatgac
gggaagacctatttctaccagctctggtatgatcaagactatgcgagatttgagtcacct
ccaaaaacccaggccacagaggacaacaagtataagttctgcgcaagctgtgcccgtctg
gtggaaatgaggcaaaaagaaattcccagggtcatggaacagctcgaggacctggacggc
cgggttctttacagctcggccaccaaggatggcgttcagtatcgggtgggcagtggcgta
tacctcctccctgaggccttcaccttcaacatcaaactgtccagtcctgtgaagcgccca
cggaaggagcctgtggatgaagacctatacccggaacactaccggaagtactccgattac
atcaaaggcagcaatttggacgcccctgagccgtaccggattggccgcatcaaagagatc
ttctgcagcaagaagagtaacggcaggcccaacgaaacagacatcaagatcaaactcaac
aagttctacaggccagagaacacgcacaagtccacccccgcaagttaccacgcagacatc
aacctgctttactggagtgacgaggaggccgtggtggacttcaaggctgtgcagggccgc
tgcaccgtggagtatggcgaggacctgccagagtgtctccaggacttctcagcgggcggc
ccagaccgcttctacttcctcgaggcctataacgccaagagcaaaaccttcgaagacccc
ccgaaccatgcccgtagccctggaaataaggggaaggggaagggcaaagggaaaggcagg
gcaaaggctcaaacatgtgagcccagtgaacccgaggccgaaatcaaactgcctaagctg
cggaccctggatgtgttctctggctgcggcggactgtcagagggattccaccaggcaggc
atctcggaaacactgtgggccatcgagatgtgggaccccgcggcccaggccttccggcta
aacaaccccggctccacggtgttcacggaggactgcaatgtgctgctgaagctggtcatg
gctggggaggccaccaactcccgtggccagaagctgcctcagaagggggacgtggagatg
ctgtgcggagggcctccctgccaagggttcagtggcatgaaccgtttcaactcccgtacc
tactccaagttcaagaactccctggtggtttccttcctcagctactgtgactactaccgg
ccgcggtatttcctcctggagaatgtcaggaacttcgtgtccttcaagcgctccatggtg
ctgaagctcaccctccgctgcctggtccgcatgggctaccagtgcaccttcggcgtgctg
caggctgggcagtacggcgtggcccagacgcggaggcgggccatcatcctggctgctgcc
cctggagagaagctccccctgttcccggagccgctgcacgtgtttgcgccccgggcctgc
cagctgagtgtcgtcgtggacgacaagaagtttgtaagcaacataaccaggttgagctcg
ggtccgtttcgaaccatcacagtgcgggacacgatgtctgacctgcctgaggtccggaac
ggagcttcagcgctggagatctcatacaacggggagcctcagtcctggttccagaggcag
ctccggggctcgcagtaccagcccatcctcagggaccacatctgtaaggacatgagtgcg
ttggtggccgcccgcatgcggcacatccctctggccccgggctcagactggcgcgacctg
cccaacatcgaggtccggctatcggatggcacgatggcccggaagctgcggtatacttac
cacgacaggaagaatggctgcagctgcaccggagccctccgcggggtctgctcctgcgtg
gaagccggcaaagcctgtgaccccgccgccagacagttcaacaccctcatcccctggtgc
ctgccccacactgggaacaggcacaaccactgggccggcctctatgggcggctggagtgg
gacggcttcttcagcacaaccgtcaccaaccctgagcccatgggcaagcagggccgcgtg
ctccaccccgagcagcaccgtgttgtgagtgtgcgggagtgcgcccgctcccagggcttc
ccggacacctaccggctgtttggcaacatcctggacaagcaccggcaggtgggcaacgcc
gtaccaccccccctggccaaggccattggcttggagatcaagtgctgcatgttggccaaa
gctcgagagagtgcctcagttaaaatcaaggaggagaaaacaactgaagactag

  All links  
Ontology (6)   
   KEGG BRITE (6)   
Pathway (4)   
   KEGG PATHWAY (3)   
   KEGG MODULE (1)   
Chemical substance (4)   
   KEGG COMPOUND (4)   
Chemical reaction (2)   
   KEGG ENZYME (1)   
   KEGG REACTION (1)   
Genome (1)   
   KEGG GENOME (1)   
Gene (3)   
   KEGG ORTHOLOGY (1)   
   NCBI-PROTEINID (1)   
   NCBI-Gene (1)   
Protein sequence (5)   
   RefSeq(pep) (5)   
DNA sequence (5)   
   RefSeq(nuc) (5)   
Protein domain (6)   
   Pfam (6)   
All databases (36)   

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