KEGG   Manis javanica (Malayan pangolin): 108402611
Entry
108402611         CDS       T06054                                 
Symbol
TH
Name
(RefSeq) tyrosine 3-monooxygenase
  KO
K00501  tyrosine 3-monooxygenase [EC:1.14.16.2]
Organism
mjv  Manis javanica (Malayan pangolin)
Pathway
mjv00350  Tyrosine metabolism
mjv00790  Folate biosynthesis
mjv01100  Metabolic pathways
mjv04728  Dopaminergic synapse
mjv04917  Prolactin signaling pathway
mjv05012  Parkinson disease
mjv05030  Cocaine addiction
mjv05031  Amphetamine addiction
mjv05034  Alcoholism
Module
mjv_M00042  Catecholamine biosynthesis, tyrosine => dopamine => noradrenaline => adrenaline
Brite
KEGG Orthology (KO) [BR:mjv00001]
 09100 Metabolism
  09105 Amino acid metabolism
   00350 Tyrosine metabolism
    108402611 (TH)
  09108 Metabolism of cofactors and vitamins
   00790 Folate biosynthesis
    108402611 (TH)
 09150 Organismal Systems
  09152 Endocrine system
   04917 Prolactin signaling pathway
    108402611 (TH)
  09156 Nervous system
   04728 Dopaminergic synapse
    108402611 (TH)
 09160 Human Diseases
  09164 Neurodegenerative disease
   05012 Parkinson disease
    108402611 (TH)
  09165 Substance dependence
   05030 Cocaine addiction
    108402611 (TH)
   05031 Amphetamine addiction
    108402611 (TH)
   05034 Alcoholism
    108402611 (TH)
Enzymes [BR:mjv01000]
 1. Oxidoreductases
  1.14  Acting on paired donors, with incorporation or reduction of molecular oxygen
   1.14.16  With reduced pteridine as one donor, and incorporation of one atom of oxygen into the other donor
    1.14.16.2  tyrosine 3-monooxygenase
     108402611 (TH)
SSDB
Motif
Pfam: Biopterin_H TH_ACT TOH_N LTP_2
Other DBs
NCBI-GeneID: 108402611
NCBI-ProteinID: XP_017524746
Position
Unknown
AA seq 493 aa
MPTPSAVPQAKGFRRAVSELDSKQAEAIMSPRFVGRRQSLIEDARKVREKAEAAAASLEP
REALEATAVRERDGKAMLNLLFTLRGAKPPVLSRAVKAFEMFEAQILHLETRPAQRPREG
GPHLEYFVRCELPSANLPALLGSVRQVAEDVRSAGENKLLWFPRKVSELDKCHHLVTKFD
PDLDLDHPGFSDQAYRQRRKMIAEIAFQYRHGDPIPRVEYTAEENATWKEVYTTLRGLYT
AHACREHLEAFELLERLSGYREDSIPQLEDVSRFLKERTGFQLRPVAGLLSARDFLASLA
FRVFQCTQYIRHASSPMHSPEPDCCHELLGHVPMLANRTFAQFSQDIGLASLGASDEEIE
KLSTLYWFTVEFGLCKQNGQVKAYGAGLLSSYGELLHALSAEPEVRAFDPDEAAVQPYQD
QTYQSVYFMSESFSDARDKFRGYVSRIQRPFSVKFDPYTLAIDVLDSPHTIQHSLEGVQD
ELQTLTQALSAIS
NT seq 1482 nt   +upstreamnt  +downstreamnt
atgcccactcccagcgccgtgccgcaggccaagggcttccgcagggctgtctcggagctg
gactccaagcaggctgaggccatcatgtctccacgcttcgtcggtcggcggcagagcctc
attgaggatgcgcgcaaggtgcgggagaaggcagaggctgcggctgcctccttggagccc
agggaggccctggaggccacggctgtccgtgagagggatgggaaggccatgctgaacctg
ctcttcaccctgcggggcgccaagccccctgtgttgtctcgtgccgtgaaggcctttgag
atgtttgaagcccaaatcttacacctggagacacggccggcccagaggccacgggagggg
ggcccccacctggagtactttgtgcgctgcgagctgcccagtgccaacctacctgccctg
ctcggctccgtgcgccaggtggcggaggacgtgcgcagcgccggggagaacaagctcctc
tggttcccaaggaaagtctctgaactggacaagtgtcaccacctggtcaccaagtttgac
cctgacctggacttggatcacccgggcttctcggaccaggcgtaccgccagcgcaggaag
atgatcgccgagatagccttccagtacaggcatggcgaccctattccccgagtggagtac
acagccgaggagaacgccacctggaaggaggtgtacaccaccctcaggggcctctacact
gcccacgcctgccgggagcatctggaagccttcgagctgctggagcggctcagcggctac
cgggaagacagcatcccgcagctggaggacgtgtcccgcttcctgaaggagcggacgggc
ttccagctgcggcccgtggccggcctgctgtccgcccgggacttcctggccagcctagcc
ttccgtgtcttccagtgtacacagtacatccgccacgcctcctcgcccatgcactcccct
gagccggactgctgccatgaactgctggggcacgtacccatgctggccaaccggaccttt
gcccagttctcccaggacattggccttgcgtccttaggggcatcagatgaggaaattgag
aagctgtccacgctatactggttcacggtggagtttgggctgtgcaagcagaatggccag
gtgaaggcctacggtgccgggctgctgtcctcctacggggagctcctgcacgccctgtct
gcggagcctgaggtccgggccttcgaccctgatgaggcagccgtgcagccctaccaggac
cagacttaccagtcggtctacttcatgtccgagagtttcagcgatgccagggacaagttc
aggggctatgtctcccgcatccagcgtcccttctctgtgaagtttgacccatacacgctg
gccattgacgtgctggacagtccccacacgatccagcactcgctagagggtgtccaggac
gagctgcagaccctcacccaggcgctgagcgccatcagctag

  All links  
Ontology (2)   
   KEGG BRITE (2)   
Pathway (10)   
   KEGG PATHWAY (9)   
   KEGG MODULE (1)   
Chemical substance (7)   
   KEGG COMPOUND (7)   
Chemical reaction (3)   
   KEGG ENZYME (1)   
   KEGG REACTION (2)   
Genome (1)   
   KEGG GENOME (1)   
Gene (3)   
   KEGG ORTHOLOGY (1)   
   NCBI-PROTEINID (1)   
   NCBI-Gene (1)   
Protein sequence (1)   
   RefSeq(pep) (1)   
DNA sequence (1)   
   RefSeq(nuc) (1)   
Protein domain (4)   
   Pfam (4)   
All databases (32)   

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