KEGG   Manis javanica (Malayan pangolin): 108408834
Entry
108408834         CDS       T06054                                 
Symbol
ITGA4
Name
(RefSeq) integrin alpha-4
  KO
K06483  integrin alpha 4
Organism
mjv  Manis javanica (Malayan pangolin)
Pathway
mjv04151  PI3K-Akt signaling pathway
mjv04510  Focal adhesion
mjv04512  ECM-receptor interaction
mjv04514  Cell adhesion molecules
mjv04640  Hematopoietic cell lineage
mjv04670  Leukocyte transendothelial migration
mjv04672  Intestinal immune network for IgA production
mjv04810  Regulation of actin cytoskeleton
mjv04820  Cytoskeleton in muscle cells
mjv05135  Yersinia infection
mjv05140  Leishmaniasis
mjv05165  Human papillomavirus infection
mjv05410  Hypertrophic cardiomyopathy
mjv05412  Arrhythmogenic right ventricular cardiomyopathy
mjv05414  Dilated cardiomyopathy
Brite
KEGG Orthology (KO) [BR:mjv00001]
 09130 Environmental Information Processing
  09132 Signal transduction
   04151 PI3K-Akt signaling pathway
    108408834 (ITGA4)
  09133 Signaling molecules and interaction
   04512 ECM-receptor interaction
    108408834 (ITGA4)
   04514 Cell adhesion molecules
    108408834 (ITGA4)
 09140 Cellular Processes
  09144 Cellular community - eukaryotes
   04510 Focal adhesion
    108408834 (ITGA4)
  09142 Cell motility
   04820 Cytoskeleton in muscle cells
    108408834 (ITGA4)
   04810 Regulation of actin cytoskeleton
    108408834 (ITGA4)
 09150 Organismal Systems
  09151 Immune system
   04640 Hematopoietic cell lineage
    108408834 (ITGA4)
   04670 Leukocyte transendothelial migration
    108408834 (ITGA4)
   04672 Intestinal immune network for IgA production
    108408834 (ITGA4)
 09160 Human Diseases
  09172 Infectious disease: viral
   05165 Human papillomavirus infection
    108408834 (ITGA4)
  09171 Infectious disease: bacterial
   05135 Yersinia infection
    108408834 (ITGA4)
  09174 Infectious disease: parasitic
   05140 Leishmaniasis
    108408834 (ITGA4)
  09166 Cardiovascular disease
   05410 Hypertrophic cardiomyopathy
    108408834 (ITGA4)
   05412 Arrhythmogenic right ventricular cardiomyopathy
    108408834 (ITGA4)
   05414 Dilated cardiomyopathy
    108408834 (ITGA4)
 09180 Brite Hierarchies
  09183 Protein families: signaling and cellular processes
   04147 Exosome [BR:mjv04147]
    108408834 (ITGA4)
   04515 Cell adhesion molecules [BR:mjv04515]
    108408834 (ITGA4)
   04090 CD molecules [BR:mjv04090]
    108408834 (ITGA4)
Exosome [BR:mjv04147]
 Exosomal proteins
  Exosomal proteins of haemopoietic cells  (B-cell, T-cell, DC-cell, reticulocyte, and mast cell)
   108408834 (ITGA4)
  Exosomal proteins of other cancer cells
   108408834 (ITGA4)
Cell adhesion molecules [BR:mjv04515]
 Integrins
  Integrin alpha subunits
   108408834 (ITGA4)
CD molecules [BR:mjv04090]
 Proteins
  108408834 (ITGA4)
SSDB
Motif
Pfam: Integrin_A_Ig_1 Integrin_A_Ig_2 Integrin_A_Ig_3 FG-GAP FG-GAP_3 Integrin_alpha
Other DBs
NCBI-GeneID: 108408834
NCBI-ProteinID: XP_036856132
Position
Unknown
AA seq 1074 aa
MAPGPAPDATPGTHPAPSAPGQREHQHLPAAETGRGAQRACCIPGRPHRSARGVPTSPPS
LCPSLARSLPPSSPPAPDKLRLFSWGARPCGRPSHPAKLWDSSHLVLNVPLRERMAGEAR
CGPGPRGPAVREAVLLLLCLGVPSGRPYNVDTESALLYQGPPNTLFGYSVVLHSHAANRW
LIVGAPTANWLANASVVSPGAIYRCRIAKNPDRTCEQLQLGSPSGEPCGKTCLEERDNQW
LGVTLSRQPGENGSVVTCGHRWKNIFYIKNENKLPTGVCYGMPSDLRTELSKRIAPCYQD
YVRKFGENFASCQAGISSFYTEAYIFSIDAKELNILHEMKGKKLGSYFGSSVCAVDLNAD
GFSDLLVGAPMHSIVREEGRVFVYINSGSGAVMNEMETELVGSDKYAARFGESIVNLGDI
DNDGFEDVAIGAPQEDDLRGAIYIYNGRADGVSSAFSQRIEGLQISKSLSMFGQSISGQI
DADNNGYVDIVVGAFRSNSAVLLRTRPVVIVEASLNHPESVNRTNFGCIENGLPSVCMDL
TVCFSYKGKEVPGYIVLFYNVSLDVNRKIESPSRFYFSSNGTSDVITRNIKVSSKAANCR
THQAFMRKDVRDILTPIQIEATYHLGHHVINKRSTEEFPPLQPILQQKKEKDIIKKTINF
ARFCAHENCSADLQVSAKIGFLKPHENKTYLAVGRMKTLMLNVSLFNAGDDAYETTLHIK
LPAGLYFIKILDLEEKQINCEVTDSSGIVKLDCNVGYIYVDHLSRINISFLLDVSSFNRA
EEDLNITVHAACANEGEMDNLKRNKLTVTIPLKYEVMLAVHGFVNPTSFVYGPGDENEPE
TCIAEKMNFTFHVINTGYSMAPNVSMEIMVPNSFIPQTEKLFNILDVQTTAGVCHFTPYQ
RKCASEQQKGAVETLKDILKFLSKTDKRLLFCIKADPHCLKFLCNFGKMENGKEASVHLQ
LEGRTSILEMDDTSALKFEIRATAFSEPNPKVIELNRDENVAHVLLEGLHHQKPKRHFTI
VIITSSLLLGLILLLLISYVMWKAGFFKRQYKSILQEENKRDSWSYVNSKSDDD
NT seq 3225 nt   +upstreamnt  +downstreamnt
atggcgccggggcctgcgcctgacgccacgcccgggacccacccagcacccagcgccccg
ggacagcgcgagcaccagcacctcccggctgcagaaacggggcgtggggcccagcgggcg
tgctgcatcccaggccgcccccatcgctccgcccgcggcgtccccacttctcctccctct
ctctgtccctccctcgctcgctcccttcctccctccagcccgccagcgccggacaagctg
cgcctcttctcttggggcgctcgtccctgcggccgcccgtcgcatcccgcgaaactttgg
gacagtagccatttggtgttgaatgttcccctcagagagcgcatggctggggaagcgagg
tgcgggccgggtccccgagggcccgccgtccgggaggcggtgcttctgctcctgtgtctg
ggggtcccgagcgggcgcccctacaacgtggacaccgagagcgcgctgctttaccagggg
ccccccaacaccctgttcggctactcggtggtgctgcacagccacgcggcgaaccgatgg
ctcatagtgggggcgcccacggccaactggctcgccaatgcttcagtggtcagtcccgga
gcgatttacagatgcaggatagcaaaaaatccagaccggacatgcgaacaactccagctg
ggtagccctagtggagaaccttgtggaaagacttgcttggaagaaagagacaatcagtgg
ctgggggtcacgctttccagacagccaggagaaaacggatctgttgtgacttgtggacat
agatggaaaaatatattttatataaagaatgaaaataagctccccacaggagtttgctat
ggaatgccctctgatttacgaacagaattaagtaaaagaatagctccatgttaccaagat
tatgtgagaaaatttggagaaaattttgcatcatgtcaagctggaatatctagtttttat
acagaggcatatatattcagcattgatgccaaagaactaaatatcttacatgaaatgaaa
ggtaaaaagctcggctcttattttggatcttctgtctgtgccgtggacctcaatgcagat
ggcttctcagacctgctggtgggagcccccatgcacagcatcgtcagggaggagggcaga
gtgtttgtgtacatcaactccggctcgggagcagtaatgaatgaaatggaaacagaactt
gttgggagtgacaaatacgctgcgagatttggagaatctatagttaatcttggcgacatt
gataatgatggctttgaagatgttgctattggagctccacaagaagacgacttgcgaggc
gctatttatatttacaatggcagagcagatggagtatcatcagcattttcacagagaatt
gaaggactccaaatcagcaaatcattaagtatgtttggacagtctatctctggacaaatt
gatgcagataataatggatatgtagatatagtggttggtgcttttcggtccaattctgct
gtattgctaaggacaagacctgtagtgattgttgaagcttctttaaaccatcctgagtca
gtaaatagaacaaattttggctgtattgaaaatggattgccatctgtgtgtatggatcta
accgtctgtttctcatataagggcaaggaggttccaggttatattgttttgttttataac
gtgagtctagatgtgaaccggaagatagagtctccatcgagattttacttttcctctaat
ggaacatctgatgtgatcaccagaaacataaaggtgtcaagcaaagcagctaactgtaga
acacatcaagcctttatgcggaaagatgtacgggacatcctcaccccaattcagatcgaa
gctacttaccaccttgggcatcatgtcatcaataaacgaagcacagaggaatttccacca
cttcagccaattcttcagcagaagaaagaaaaagacataatcaaaaaaactataaacttt
gcaagattctgtgcccatgaaaactgttctgctgatttacaggtttctgcaaaaattggg
tttttgaagccacatgaaaataagacctatcttgctgttggacgtatgaagacattaatg
ttgaatgtgtccctgtttaatgctggagatgatgcatatgaaacaactctgcatatcaaa
ctacctgctggtctttacttcattaagatcttagatctggaagagaaacaaataaactgt
gaagtaacagacagctctggcatagtaaaacttgactgcaatgttggttatatatatgta
gatcatttatcaaggatcaatattagctttctcctggatgtgagctcattcaacagagca
gaagaggatctcaatatcacagtgcacgctgcctgtgcaaatgaaggggaaatggacaac
ctgaagcgtaacaaactaactgtaacaatacctctcaaatatgaagtcatgctagctgtt
catgggtttgtaaacccaacttcatttgtatacggaccaggggatgaaaatgagcccgaa
acgtgcatagcagagaaaatgaacttcactttccatgtcatcaacactggctatagcatg
gctccaaatgttagtatggaaataatggtaccaaattcttttatcccccaaaccgagaag
ctgttcaacattttggatgtccagactactgctggagtatgtcactttacaccttaccaa
agaaagtgtgcatcagagcagcaaaaaggtgcagtggagaccctgaaagacatattgaag
ttcttgtcaaagactgataagaggctactgttctgcataaaagctgatccacattgtttg
aaattcttatgcaattttgggaaaatggaaaatgggaaagaagctagtgttcacctgcag
ctggaaggccggacatccattttagaaatggatgacacttcagctctcaagtttgaaata
agagcaacagctttttcagagccaaatccaaaagttattgaacttaacagggatgagaat
gttgcacatgttctgcttgaaggactacatcatcaaaaacccaaacgtcatttcactata
gtgattattacaagtagcttgttactcggacttattttacttctactgatttcctatgtt
atgtggaaggctggcttctttaaaagacagtacaaatctatcctacaagaagaaaacaaa
agagacagttggagttatgttaacagtaaaagcgatgatgattaa

  All links  
Ontology (4)   
   KEGG BRITE (4)   
Pathway (15)   
   KEGG PATHWAY (15)   
Genome (1)   
   KEGG GENOME (1)   
Gene (3)   
   KEGG ORTHOLOGY (1)   
   NCBI-PROTEINID (1)   
   NCBI-Gene (1)   
Protein sequence (1)   
   RefSeq(pep) (1)   
DNA sequence (1)   
   RefSeq(nuc) (1)   
Protein domain (6)   
   Pfam (6)   
All databases (31)   

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