KEGG   Mycobacterium leprae Br4923: MLBr01129
Entry
MLBr01129         CDS       T00842                                 
Symbol
hom
Name
(GenBank) homoserine dehydrogenase
  KO
K00003  homoserine dehydrogenase [EC:1.1.1.3]
Organism
mlb  Mycobacterium leprae Br4923
Pathway
mlb00260  Glycine, serine and threonine metabolism
mlb00270  Cysteine and methionine metabolism
mlb00300  Lysine biosynthesis
mlb01100  Metabolic pathways
mlb01110  Biosynthesis of secondary metabolites
mlb01120  Microbial metabolism in diverse environments
mlb01230  Biosynthesis of amino acids
Module
mlb_M00017  Methionine biosynthesis, aspartate => homoserine => methionine
mlb_M00018  Threonine biosynthesis, aspartate => homoserine => threonine
Brite
KEGG Orthology (KO) [BR:mlb00001]
 09100 Metabolism
  09105 Amino acid metabolism
   00260 Glycine, serine and threonine metabolism
    MLBr01129 (hom)
   00270 Cysteine and methionine metabolism
    MLBr01129 (hom)
   00300 Lysine biosynthesis
    MLBr01129 (hom)
Enzymes [BR:mlb01000]
 1. Oxidoreductases
  1.1  Acting on the CH-OH group of donors
   1.1.1  With NAD+ or NADP+ as acceptor
    1.1.1.3  homoserine dehydrogenase
     MLBr01129 (hom)
SSDB
Motif
Pfam: Homoserine_dh NAD_binding_3 ACT GFO_IDH_MocA Sacchrp_dh_NADP
Other DBs
NCBI-ProteinID: CAR71224
UniProt: A0A0H3MQD4
Position
1319682..1321007
AA seq 441 aa
MFSDERTVGVAVLGLGNVGSEVVRIIEGSADDLAARIGAPLMLRGIGVRRVAVDRGVPVD
LLTDNIEELVSRADVDIVVEVMGPVELSRKAILSALEHGKSVVTANKALLAASTGELAQA
AESAHVDLYFEAAVAGAIPVIRPLTQSLAGDTVLRVAGIVNGTTNYILSAMDSTGADYDS
ALAGARALGYAEADPTADVEGHDAAAKAAILASIAFHTRVTADDVYREGITKITPADFVS
ARALGCTIKLLFICERITAADGQQRVSARVYPALVPMSHPLATVSGAFNAVVVEAEAAGR
LMFYGQGAGGAPTASAVTGDLVMAARNRVLGSRGPKESKYAQLPMETIGFISTRYYVSMN
VADKPGVLSGVAAEFAKREVSIAEVRQEGVVDDGGRRVGARIVVVTHGATDAALSETVDA
LADLDVVQGVTSVLRLEGISL
NT seq 1326 nt   +upstreamnt  +downstreamnt
gtgttcagtgatgaaaggacggtcggtgtagcggtactcgggttgggcaatgtcggcagc
gaagttgttcgcattatcgagggcagcgctgacgacctcgcggctcgtatcggcgctcca
ttgatgctgcgtggcatcggggtgcgtcgtgtcgccgtcgaccggggtgttccggtcgat
ttgttgaccgacaacattgaagaactcgtctcccgtgcggacgtcgacattgtcgttgaa
gtgatgggaccagttgagctgtctcgcaaggcgatcttgtcagcgctcgaacatggcaag
tctgtcgtcacggcgaacaaggcgttgcttgccgcctccactggtgaattggcgcaggct
gccgaaagtgcgcatgtcgacttgtattttgaagctgcagtagcaggtgccatcccggta
atccgcccattaacccagtcactggccggtgacaccgtgctgcgggtggctggtattgtg
aacggtaccaccaactacatcttgtctgcgatggacagcaccggtgccgactacgacagc
gcgctggccggtgcgagagcgctcggctacgccgaagccgatcccaccgcggacgtcgaa
ggccatgacgctgcggctaaggccgcgatcctggcatcgatcgctttccacactcgggta
accgccgatgatgtctatcgcgagggcatcaccaagatcactccggccgacttcgtgtcg
gcgcgggcgttaggttgcaccattaagctgctgttcatttgcgagcgcattaccgccgcc
gatggccagcaacgagtttcggcccgcgtttatcctgcattggtccccatgtcacatccg
cttgccacggtcagcggagcgttcaacgccgtggtggtggaggctgaggccgccgggcgg
ctgatgttctacggccagggcgccggtggtgctcctaccgcgtcggcggtgactggtgac
ttggtaatggcggcgcgcaaccgagtgctcggcagtcgcggtccaaaagaatccaagtat
gctcaattgcctatggaaacaataggtttcatttctactcgatattacgtgagcatgaat
gtagccgacaagcctggtgtattatcaggggtagcagcagaattcgccaagcgcgaagtg
agcatcgccgaagttcgtcaagaaggtgtggtggatgacggcggacgacgggtgggagcc
cgtattgtagtggtcactcatggcgccaccgacgccgcgctctccgaaaccgtcgatgcg
ttggctgacttagacgtcgtgcagggtgtcacaagtgtgttgcgactggaaggaatcagc
ctgtga

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Ontology (2)   
   KEGG BRITE (2)   
Pathway (9)   
   KEGG PATHWAY (7)   
   KEGG MODULE (2)   
Chemical substance (7)   
   KEGG COMPOUND (7)   
Chemical reaction (3)   
   KEGG ENZYME (1)   
   KEGG REACTION (2)   
Genome (1)   
   KEGG GENOME (1)   
Gene (3)   
   KEGG ORTHOLOGY (1)   
   NCBI-PROTEINID (1)   
   OC (1)   
Protein sequence (1)   
   UniProt (1)   
Protein domain (5)   
   Pfam (5)   
All databases (31)   

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