KEGG   Mycobacterium leprae TN: ML0910
Entry
ML0910            CDS       T00047                                 
Symbol
murF
Name
(GenBank) UDP-N-acetylmuramoylalanyl-D-glutamyl-2,6-diaminopimelate--D-alanyl-D-alanyl ligase (D-alanine:D-alanine-adding enzyme)
  KO
K01929  UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine ligase [EC:6.3.2.10]
Organism
mle  Mycobacterium leprae TN
Pathway
mle00300  Lysine biosynthesis
mle00550  Peptidoglycan biosynthesis
mle01100  Metabolic pathways
mle01502  Vancomycin resistance
Brite
KEGG Orthology (KO) [BR:mle00001]
 09100 Metabolism
  09105 Amino acid metabolism
   00300 Lysine biosynthesis
    ML0910 (murF)
  09107 Glycan biosynthesis and metabolism
   00550 Peptidoglycan biosynthesis
    ML0910 (murF)
 09160 Human Diseases
  09175 Drug resistance: antimicrobial
   01502 Vancomycin resistance
    ML0910 (murF)
Enzymes [BR:mle01000]
 6. Ligases
  6.3  Forming carbon-nitrogen bonds
   6.3.2  Acid-D-amino-acid ligases (peptide synthases)
    6.3.2.10  UDP-N-acetylmuramoyl-tripeptide---D-alanyl-D-alanine ligase
     ML0910 (murF)
SSDB
Motif
Pfam: Mur_ligase_M Mur_ligase_C Mur_ligase
Other DBs
NCBI-ProteinID: CAC31291
Pasteur: ML0910
UniProt: O69556
Position
1077590..1079143
AA seq 517 aa
MIDLTVARVTEIVGGALVDISPEEAAERRVTGSVEFDSRAVGPGGLFLALPGARSDGHDH
AASAIAAGAVAVLAARPVGVPAIVVAPDPRTGDGGLTGVLEHDADGSGAAVLAALAKLAK
AVAAELVAGGLTIIGITGSSGKTSTKDLVAVVLELLGEVVAPPESFNNELGHPWTVLRAT
RSTDYLILEMSARRPGNIAALAAIAPPKIGVVLNVGTAHLGEFGSREAIARTKTELPQAI
MQSGVVILNVDDPAVAAMADATVARVIRVSRGSYSHPGSPNSPDVWTGPVSLDELARPRF
TLHTRDPRAGATEIQLGVYGDHQVANALCAAAVGLECGASVEEVAVALAATGPVSRHRMQ
VTTRADGVTVIDDTYNANPDSMRAGLQALAWIAHGGTHDKNQPGSCARRSWAVLGEMAEL
GEDSITEHDRIGRLAVRLDVSRLVVVGGGRSINAMHRGAVMEGSWGLETVNVADPAAALT
LLRAEVRPGDVVLIKASHSVGLGALADVLVGDGAIRP
NT seq 1554 nt   +upstreamnt  +downstreamnt
atgatcgacctgacggttgcccgggttaccgagatcgtcggtggcgcgttggtcgatatc
tctcccgaggaggccgccgagcgtcgcgtcaccggcagcgtggaatttgattcgcgggct
gttggccccggcggtctattcctggccttgccgggggcccgctcggacggacatgaccat
gctgcttcggcgatagcggccggtgcggtggctgtgttggctgcccggccggtcggcgtt
cccgccatcgtagttgctcctgaccctcgcacgggtgacggcgggctgactggggtgctt
gagcacgatgcagacggatcgggcgcggcggtgctggccgccttggctaagttggccaag
gcggtggccgcggagctggtagctggcgggctgactatcattgggattaccggatcgtcg
gggaagacatccaccaaagatttggtggccgtcgtgctggagttgctcggtgaggtggtg
gcgccacccgagtcgttcaacaatgaactgggtcatccctggacagtgttgcgtgcaacc
cgtagcacggactatttgattctggagatgtcggcacgccgtcccggtaatattgccgcg
ttggcggcgatcgccccaccaaagataggggttgtcctcaacgtcggcactgcgcaccta
ggtgagtttggctcccgggaagccatcgcgcgaactaaaaccgagcttccgcaagctatt
atgcagtccggtgtggtcatactcaacgtcgatgacccggcggtggcggcgatggctgac
gcgaccgtggcccgcgtgattcgggttagtcgcggtagttatagccatccggggtcacca
aacagcccagacgtttggactggtccggtgtcgctcgacgaacttgctaggccgcgcttc
acgctgcatactcgagatccacgcgccggcgccaccgaaatccaactcggcgtgtacggc
gatcatcaggtcgccaacgccttgtgcgcggctgcggtcggactggaatgcggtgctagc
gtcgaggaagtggcggtcgcgcttgccgcgacagggccggtgtcgcggcatcggatgcag
gtgaccacgcgcgctgacggggtgacggtgatcgacgacacctacaacgccaaccccgac
tcgatgcgggccgggctacaggctttggcctggatcgcgcatggtgggacccatgataag
aaccagccaggttcttgtgctcgacgaagctgggcggtgttgggtgagatggccgagctt
ggagaggactcgataaccgaacacgatcgcatcggccggctagcggtgcgcttagatgtg
tctcgactcgttgtcgtgggagggggaaggtcgataaacgccatgcaccgcggagcggtt
atggaaggttcttggggtttagagacggttaatgtggccgaccccgctgctgccctgaca
ttgttgcgggctgaagtacgacccggcgacgtggtcctgatcaaggcgtcgcattcggtc
ggcctaggagcgctggctgatgtactggtgggcgacggggccatccgcccatga

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Ontology (2)   
   KEGG BRITE (2)   
Pathway (4)   
   KEGG PATHWAY (4)   
Chemical substance (8)   
   KEGG COMPOUND (8)   
Chemical reaction (3)   
   KEGG ENZYME (1)   
   KEGG REACTION (2)   
Genome (1)   
   KEGG GENOME (1)   
Gene (4)   
   KEGG ORTHOLOGY (1)   
   NCBI-PROTEINID (1)   
   OC (1)   
   PASTEUR (1)   
Protein sequence (2)   
   UniProt (1)   
   SWISS-PROT (1)   
Protein domain (3)   
   Pfam (3)   
All databases (27)   

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