KEGG   Mus musculus (house mouse): 68188
Entry
68188             CDS       T01002                                 
Symbol
Sympk, 1500016F02Rik, 4632415H16Rik, SPK, SYM
Name
(RefSeq) symplekin
  KO
K06100  symplekin
Organism
mmu  Mus musculus (house mouse)
Pathway
mmu03015  mRNA surveillance pathway
mmu04530  Tight junction
Brite
KEGG Orthology (KO) [BR:mmu00001]
 09120 Genetic Information Processing
  09122 Translation
   03015 mRNA surveillance pathway
    68188 (Sympk)
 09140 Cellular Processes
  09144 Cellular community - eukaryotes
   04530 Tight junction
    68188 (Sympk)
 09180 Brite Hierarchies
  09182 Protein families: genetic information processing
   03021 Transcription machinery [BR:mmu03021]
    68188 (Sympk)
   03019 Messenger RNA biogenesis [BR:mmu03019]
    68188 (Sympk)
Transcription machinery [BR:mmu03021]
 Eukaryotic type
  RNA polymerase II system
   Other transcription-related factors
    Transcription termination factor
     68188 (Sympk)
Messenger RNA biogenesis [BR:mmu03019]
 Eukaryotic type
  mRNA processing factors
   3' end processing
    Cleavage stimulation factor (CSTF) complex
     68188 (Sympk)
    U7-dependent histone pre-mRNA processing factors
     68188 (Sympk)
SSDB
Motif
Pfam: Symplekin_C SYMPK_PTA1_N PDS5 Cnd1 Cohesin_HEAT
Other DBs
NCBI-GeneID: 68188
NCBI-ProteinID: NP_080881
MGI: 1915438
Ensembl: ENSMUSG00000023118
UniProt: Q80X82
Position
7:18758321..18788542
AA seq 1288 aa
MASSSGDSVTRRSVASQFFTQEEGPSIDGMTTSERVVDLLNQAALITNDSKITVLKQVQE
LIINKDPTLLDNFLDEIIAFQADKSIEVRKFVIGFIEEACKRDIELLLKLIANLNMLLRD
ENVNVVKKAILTMTQLYKVALQWMVKSRVISDLQEACWDMVSSMAGEIILLLDSDNDGIR
THAIKFVEGLIVTLSPRMADSEVPRRQEHDISLDRIPRDHPYIQYNVLWEEGKAAVEQLL
KFMVHPAISSINLTTALGSLANIARQRPMFMSEVIQAYETLHANLPPTLAKSQVSSVRKN
LKLHLLSVLKHPASLEFQAQITTLLVDLGTPQAEIARNMPSSKDSRKRPRDDTDSTLKKM
KLEPNLGEDDEDKDLEPGPSGTSKASAQISGQSDTDITAEFLQPLLTPDNVANLVLISMV
YLPETMPASFQAIYTPVESAGTEAQIKHLARLMATQMTAAGLGPGVEQTKQCKEEPKEEK
VVKPESVLIKRRLSVQGQAISVVGSQSTMSPLEEEVPQAKRRPEPIIPVTQPRLAGAGGR
KKIFRLSDVLKPLTDAQVEAMKLGAVKRILRAEKAVACSGAAQVRIKILASLVTQFDSGF
KAEVLSFILEDVRARLDLAFAWLYQEYNAYLAAGTSGTLDKYEDCLICLLSGLQEKPDQK
DGIFTKVVLEAPLITESALEVIRKYCEDESRAYLGMSTLGDLIFKRPSRQFQYLHVLLDL
SSHEKDRVRSQALLFIKRMYEKEQLREYVEKFALNYLQLLVHPNPPSVLFGADKDTEVAA
PWTEETVKQCLYLYLALLPQNHKLIHELAAVYTEAIADIKRTVLRVIEQPIRGMGMNSPE
LLLLVENCPKGAETLVTRCLHSLTDKVPPSPELVKRVRDLYHKRLPDVRFLIPVLNGLEK
KEVIQALPKLIKLNPIVVKEVFNRLLGTQHGEGNSALSPLNPGELLIALHNIDSVKCDMK
SIIKATNLCFAERNVYTSEVLAVVMQQLMEQSPLPMLLMRTVIQSLTMYPRLGGFVMNIL
ARLIMKQVWKYPKVWEGFIKCCQRTKPQSFQVILQLPPQQLGAVFDKCPELREPLLAHVR
SFTPHQQAHIPNSIMTILEATGKQEPEVKEAPSGPLEEDDLEPLALALAPAPAPAPAPAP
APAPAPRPPQDLIGLRLAQEKALKRQLEEEQKQKPTGIGAPAACVSSTPSVPAAARAGPT
PAEEVMEYREEGPECETPAIFISMDDDSGLAETTLLDSSLEGPLPKEAAAVGSSSKDERS
PQNLSHAVEEALKTSSPETREPESKGNS
NT seq 3867 nt   +upstreamnt  +downstreamnt
atggcaagcagcagcggggacagtgtcacccgccggagtgtggcatcacagtttttcaca
caagaagaagggccaagcatcgatggcatgaccacttctgagagggtggtagatcttctg
aaccaggctgcattgatcaccaatgactccaagatcacagtgctcaaacaggtccaagag
ctgatcatcaacaaggaccccaccctgcttgacaacttcctggatgagatcatcgctttc
caagcagacaaatccattgaagtgcgcaagtttgtcattggcttcattgaggaggcatgc
aagcgggacattgagctgctgctaaaactgatcgccaacctcaacatgctattgcgggat
gaaaatgtgaacgtggttaagaaggccatcctcaccatgacccagctctacaaggtggcc
ctacagtggatggtgaagtctcgagtcatcagtgatctccaggaggcctgctgggacatg
gtgtcctctatggctggggaaatcatcctgcttttggattctgacaacgatggcatccgt
acacatgccatcaagtttgtggagggcctcattgtcaccctgtcaccccgcatggctgac
tcagaggtcccacgacgccaggagcatgacatcagtctggaccgcattcctcgagatcac
ccctacatccagtacaatgtcctatgggaagaaggcaaggcagctgtggagcagctgctg
aagttcatggtgcaccccgccatctcctccatcaacctgaccacagcgctcggctccctt
gccaacatcgcccgccagagacccatgttcatgtccgaggtgatccaggcctatgagact
ctgcatgccaacctgcccccaacgctggccaagtcccaggtgagcagtgtgcggaagaac
cttaagctgcacttgctcagtgtgctcaagcaccctgcctccttggagttccaggcccag
atcaccaccctgctggtggatctgggcacgccccaggctgagatcgcccgaaacatgcct
agcagcaaggactcccgcaagcggccccgggacgatacagattccacgctcaagaagatg
aagctggagcccaacttgggagaagacgatgaggacaaagacttggagcctggcccatca
gggacgtcaaaggcgtcagcccagatctcaggccagtcagacacggacatcactgctgag
ttcttgcagcctctgctgacacctgacaatgtggccaatctggtcctcatcagcatggtg
tacctgcctgagaccatgcctgcctccttccaagccatctacacccctgtggagtcagca
ggcactgaagcccagatcaagcacctggctcgactcatggccacacagatgacagctgca
ggactgggtcctggtgtggaacagacgaaacagtgcaaggaggagcccaaggaggagaag
gtggtaaagccggagagcgtcctgatcaagcggcgcctgtcggtgcagggccaggccatc
tctgtggtaggctctcagagcaccatgtctcccttggaggaggaggtaccccaggccaag
aggaggccagaacccatcatccctgtcacgcagccacggctggcaggcgcaggtgggcgc
aagaagatcttccgtctgagcgatgtgctgaagcccctgacagatgcccaggtggaagcc
atgaagctaggagctgtgaagcggatcctgagggctgagaaggctgtagcctgcagtggg
gcagcccaggtgcgcatcaagatcctggccagcctcgtaacacagttcgactccggattc
aaggcagaggtgctgtcctttatcctggaagatgtccgggcccgtctggacctggctttt
gcctggctctaccaggaatataatgcctacctggcagcagggacctcaggcactctggac
aaatatgaggattgcctcatctgcctgctctctggactacaagagaaaccagaccagaaa
gatgggatctttaccaaggtggttttggaggccccactgatcactgagagtgccttggag
gtgatacggaagtactgtgaggatgagagtcgtgcctacctgggcatgtcgacacttgga
gacctgatcttcaagcgcccttctcgccagttccagtatctgcacgttcttcttgacctc
agctctcacgagaaggacagggtgcgctcccaggccttgctcttcattaagcgaatgtat
gagaaggagcagcttcgagagtatgtggagaaatttgccctcaactacctgcagctcctg
gtccaccccaacccaccctcggtgctgtttggagccgacaaggacacagaggtggccgca
ccctggacagaggaaacagtgaagcagtgtttgtatctgtatctggctctcctgcctcag
aaccacaagctgatccatgagctggcagccgtgtacactgaagccatcgctgacatcaag
cggacagtgctgagggtcattgagcagccgatccgagggatgggcatgaactctccagag
ctgctgctgctggtagaaaactgtcccaagggggcagagacgctggtcacccgctgcctg
cacagcctcaccgacaaagtgccaccatccccagaactggtgaagcgggtccgagacctg
taccacaaacggctgcctgatgtgcgcttcctcatccccgtgctcaatgggttggagaag
aaagaggtgatccaggcgctgcccaagctcatcaaactcaaccccattgtggtgaaggaa
gtcttcaaccgcctgctaggcactcagcacggtgaggggaactcggccctgtcccccctg
aatccaggagagctgctgattgcattgcacaatattgactctgtgaagtgtgacatgaag
tccatcatcaaagccaccaacctgtgttttgcggagcggaatgtgtacacgtcggaagtg
ctagctgtggtgatgcagcagctgatggagcaaagccctctgcccatgctgctcatgcgg
accgtcatccagtccctcaccatgtacccccgcctggggggcttcgtcatgaacatcctg
gcccgactcatcatgaagcaggtatggaagtaccccaaggtatgggagggcttcatcaag
tgctgccagcgcaccaagccacagagtttccaggtcatcctgcagctacctccacagcag
cttggcgcagtctttgacaagtgccctgagctccgggagccactgttggcccatgtgcgc
tccttcactccccaccagcaagcacacatccccaactccatcatgaccatcctggaggcc
actggaaagcaggagcccgaagtcaaggaagcaccttcagggcccctggaagaggatgac
ctggagcccttggctctggctttggccccggctccggccccggccccggccccggccccg
gccccggcccctgccccacggccccctcaggacctcatcggcctgcgattggctcaggag
aaggccctgaagaggcagctggaggaggaacagaagcagaagcccacaggcatcggagcg
cccgctgcctgtgtgtcctcaacgccctcggtgccagcagcagcccgagctgggcccacc
ccagctgaggaggtcatggaataccgggaggagggtcccgaatgcgagaccccggccatc
ttcatcagcatggacgacgactcggggctggctgaaaccacactgctggactctagtctc
gaggggcccctgcctaaggaggcagcagcagtcgggtcgagctccaaggatgagcggagc
ccccagaacctcagccatgctgtggaagaagccttgaagacctccagcccagaaaccagg
gaacccgagagcaaggggaacagctga

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