KEGG   Mus musculus (mouse): 100504404
Entry
100504404         CDS       T01002                                 

Gene name
H2-Ea, AI323765, E-alpha-f, H-2E, H-2Ea, H2-Ea-ps, I, I-E, I-Ealpha, Ia, Ia-3, Ia3, MHC-H2-Ea
Definition
(RefSeq) histocompatibility 2, class II antigen E alpha
  KO
K06752  MHC class II antigen
Organism
mmu  Mus musculus (mouse)
Pathway
mmu04145  Phagosome
mmu04514  Cell adhesion molecules
mmu04612  Antigen processing and presentation
mmu04640  Hematopoietic cell lineage
mmu04658  Th1 and Th2 cell differentiation
mmu04659  Th17 cell differentiation
mmu04672  Intestinal immune network for IgA production
mmu04940  Type I diabetes mellitus
mmu05140  Leishmaniasis
mmu05145  Toxoplasmosis
mmu05150  Staphylococcus aureus infection
mmu05152  Tuberculosis
mmu05164  Influenza A
mmu05166  Human T-cell leukemia virus 1 infection
mmu05168  Herpes simplex virus 1 infection
mmu05169  Epstein-Barr virus infection
mmu05310  Asthma
mmu05320  Autoimmune thyroid disease
mmu05321  Inflammatory bowel disease
mmu05322  Systemic lupus erythematosus
mmu05323  Rheumatoid arthritis
mmu05330  Allograft rejection
mmu05332  Graft-versus-host disease
mmu05416  Viral myocarditis
Brite
KEGG Orthology (KO) [BR:mmu00001]
 09130 Environmental Information Processing
  09133 Signaling molecules and interaction
   04514 Cell adhesion molecules
    100504404 (H2-Ea)
 09140 Cellular Processes
  09141 Transport and catabolism
   04145 Phagosome
    100504404 (H2-Ea)
 09150 Organismal Systems
  09151 Immune system
   04640 Hematopoietic cell lineage
    100504404 (H2-Ea)
   04612 Antigen processing and presentation
    100504404 (H2-Ea)
   04658 Th1 and Th2 cell differentiation
    100504404 (H2-Ea)
   04659 Th17 cell differentiation
    100504404 (H2-Ea)
   04672 Intestinal immune network for IgA production
    100504404 (H2-Ea)
 09160 Human Diseases
  09172 Infectious disease: viral
   05166 Human T-cell leukemia virus 1 infection
    100504404 (H2-Ea)
   05164 Influenza A
    100504404 (H2-Ea)
   05168 Herpes simplex virus 1 infection
    100504404 (H2-Ea)
   05169 Epstein-Barr virus infection
    100504404 (H2-Ea)
  09171 Infectious disease: bacterial
   05150 Staphylococcus aureus infection
    100504404 (H2-Ea)
   05152 Tuberculosis
    100504404 (H2-Ea)
  09174 Infectious disease: parasitic
   05145 Toxoplasmosis
    100504404 (H2-Ea)
   05140 Leishmaniasis
    100504404 (H2-Ea)
  09163 Immune disease
   05310 Asthma
    100504404 (H2-Ea)
   05322 Systemic lupus erythematosus
    100504404 (H2-Ea)
   05323 Rheumatoid arthritis
    100504404 (H2-Ea)
   05320 Autoimmune thyroid disease
    100504404 (H2-Ea)
   05321 Inflammatory bowel disease
    100504404 (H2-Ea)
   05330 Allograft rejection
    100504404 (H2-Ea)
   05332 Graft-versus-host disease
    100504404 (H2-Ea)
  09166 Cardiovascular disease
   05416 Viral myocarditis
    100504404 (H2-Ea)
  09167 Endocrine and metabolic disease
   04940 Type I diabetes mellitus
    100504404 (H2-Ea)
 09180 Brite Hierarchies
  09183 Protein families: signaling and cellular processes
   04147 Exosome [BR:mmu04147]
    100504404 (H2-Ea)
Exosome [BR:mmu04147]
 Exosomal proteins
  Exosomal proteins of haemopoietic cells  (B-cell, T-cell, DC-cell, reticulocyte, and mast cell)
   100504404 (H2-Ea)
  Exosomal proteins of epithelial cells
   100504404 (H2-Ea)
  Exosomal proteins of breast milk
   100504404 (H2-Ea)
SSDB
Motif
Pfam: MHC_II_alpha C1-set Ig_3 C2-set_2 Ig_2 Marek_A
Other DBs
NCBI-GeneID: 100504404
NCBI-ProteinID: NP_034511
MGI: 95900
Ensembl: ENSMUSG00000036322
UniProt: P04224 P14439 A0A290WGA7
Structure
PDB: 

Position
17 B1; 17 17.98 cM
AA seq 255 aa
MATIGALVLRFFFIAVLMSSQKSWAIKEEHTIIQAEFYLLPDKRGEFMFDFDGDEIFHVD
IEKSETIWRLEEFAKFASFEAQGALANIAVDKANLDVMKERSNNTPDANVAPEVTVLSRS
PVNLGEPNILICFIDKFSPPVVNVTWLRNGRPVTEGVSETVFLPRDDHLFRKFHYLTFLP
STDDFYDCEVDHWGLEEPLRKHWEFEEKTLLPETKENVVCALGLFVGLVGIVVGIILIMK
GIKKRNVVERRQGAL
NT seq 768 nt   +upstreamnt  +downstreamnt
atggccacaattggagccctggtgttaagatttttcttcattgctgttctgatgagctcc
cagaagtcatgggctatcaaagaggaacacaccatcatccaggcggagttctatctttta
ccagacaaacgtggagagtttatgtttgactttgacggcgatgagattttccatgtagac
attgaaaagtcagagaccatctggagacttgaagaatttgcaaagtttgccagctttgag
gctcagggtgcactggctaatatagctgtggacaaagctaacctggatgtcatgaaagag
cgttccaacaacactccagatgccaacgtggccccagaggtgactgtactctccagaagc
cctgtgaacctgggagagcccaacatcctcatctgtttcattgacaagttctcccctcca
gtggtcaatgtcacctggctccggaatggacggcctgtcaccgaaggcgtgtcagagaca
gtgtttctcccgagggacgatcacctcttccgcaaattccactatctgaccttcctgccc
tccacagatgatttctatgactgtgaggtggatcactggggtttggaggagcccctgcgg
aagcactgggagtttgaagagaaaaccctcctcccagaaactaaagagaatgtcgtgtgt
gctcttgggttgtttgtgggtctggtgggcatcgttgtggggattatcctcatcatgaag
ggtattaaaaaacgcaatgttgtagaacgccgacaaggagccctgtga

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