KEGG   Mus musculus (house mouse): 102098
Entry
102098            CDS       T01002                                 
Symbol
Arhgef18, A430078G23Rik, D030053O22Rik
Name
(RefSeq) rho guanine nucleotide exchange factor 18 isoform 1
  KO
K21066  A-kinase anchor protein 18
Organism
mmu  Mus musculus (house mouse)
Pathway
mmu04530  Tight junction
Brite
KEGG Orthology (KO) [BR:mmu00001]
 09140 Cellular Processes
  09144 Cellular community - eukaryotes
   04530 Tight junction
    102098 (Arhgef18)
 09180 Brite Hierarchies
  09182 Protein families: genetic information processing
   04131 Membrane trafficking [BR:mmu04131]
    102098 (Arhgef18)
Membrane trafficking [BR:mmu04131]
 Others
  Rho GTPase associated proteins
   Rho guanine nucleotide exchange factors (GEFs)
    102098 (Arhgef18)
SSDB
Motif
Pfam: PH_16 RhoGEF PH SOS1_NGEF_PH VipD-like_C PH_13 Chordopox_A30L
Other DBs
NCBI-GeneID: 102098
NCBI-ProteinID: NP_001357597
MGI: 2142567
Ensembl: ENSMUSG00000004568
UniProt: Q6P9R4
Structure
Position
8:3403339..3506601
AA seq 1405 aa
MGSEPKPYAQPLDSAAAASTTKGSCGPRKPENPDFFSTVEDEQEDGFLRHLSESTEDFSL
DMGALQGSEYLRDLGLGAPSDLHQSEVIMDPETHRQEARRESSHTSCEGASALPQRRSWE
RSRSCSGSCRRLSLDASTVDKGACLPRTLASLALNLSGNGQKIWTQGCLPVSGTPAPSSK
ECSSPEKRLRSKSVPVSCEISCMELASDSDVCTSPVQGLEPPVLECLEKDHVEPEHVLIV
QQVLQELRQYHGARQRARMSTSPGGAHSNLTWFEFLSESEDGACKIEKPGKSTRVKRSLS
SLRSRVTRQKEKGKSPAHLKDKTQDLPGKRECVNGHQLMRGTFSGHSSCPLCGEPLLNSA
SLKEHPRTTLLSDGSSPAPSRNVGMTISQKGGLQPTPSPAGSGVRLGPIAGDMDEADSVF
LKLKQTADDSLSLTSSNAESVFIEDPYIASLRCEIESDAHEFEAESWSLSVDLAYAKKQK
KEVVKRQDVLYELMQTEAHHVRTLKIMLKVYSRALQEELQFSGQAVSRLFPCADDLLDMH
SHFLARLKERRQEFLEEGSDRNYVIQKIGDVLVQQFSGETGERMKEKYAVFCSGHNDAVG
QYKLLLQQSKKFQNLIKKIGNFSIVRRLGVQECILLVTQRITKYPVLVERIIQNTEAGTE
DYKDLSQALSLIKDIISQVDAKVSEYEKDQRLKEIAAKTDQKSSGKLKNGLTFRKEDMLQ
QRQLHLEGALCWKSTSGRLKDVLAVLLTDVLLLLQEKDQKYVFASVDSKPPVISLQKLIV
REVANEEKAMFLISASMQGPEMYEMYTSSKEDRNIWMAHIRRAVESCPDEEEDVFSEAEE
KKIAEARTMKLQEFQERLSLKDQLIAQSLLEKQQIYLEMAQLSGLEESAQNRGLFRGGGD
PSETLRGEQILRSAMSEIEGIQSLICQRHLGSTSSQVEEGSVSAGLPRRAETFGGYDSVG
SPSKGGSFKRKVSNSDLRPQDWQGPASSPDSRPCDNSAPSGCCEESPQAVEMPSTESLPT
VLELELVHRVQTLSQLLLSLQAVIAQQDSYVEMQRTAIQEREKQFRLQSTRGNLLLEQER
QRNFEKQREERAGVEKLQSQLRQEQQRWERERARQQQELELAGARLQEREGEARQMRQRL
DQERTELERQRQAYQHDLERLREAQRAVDRERERLELLRRFKKQNTVPGALPPEVLAEAQ
PASHPPSFNGDGLEGHSAPAKAPGTQGSAMLHGTGPDNVERPEVARWDSAPPESRPAKSD
VPIQLLSATNQIQRQTAVQQQIPTKLAASTKGGKEKGSKSRGSQRWESSASFDLKQQLLL
SKFIGKDESASRNRRSLSPVLPAAHGSAPASDPCFPAPSPAPAATPPEAFKFGGTSLPPV
SPASSLPTTPLATTDEVSKEDVIFF
NT seq 4218 nt   +upstreamnt  +downstreamnt
atgggctctgagcccaagccatatgcccagcccctggactctgcagctgcagcctcaacc
accaagggtagctgtggacccaggaaacctgagaatccagatttcttctcaactgtggaa
gatgagcaggaagatggttttctgaggcacctcagcgagagcacagaagacttcagcctg
gatatgggagcccttcagggcagcgagtacctccgggatctaggcttaggggccccttct
gacctccatcagtctgaagtgattatggaccctgagacccacagacaagaagccagaaga
gagtcctcccacacaagctgtgaaggagcttcggccctgccacaaagacgcagctgggag
aggtcccggagctgctcagggagctgtcgaaggctcagccttgatgcctccacggtggac
aaaggggcctgtctcccccggactctggctagccttgctctgaatctgtctggaaatggg
cagaagatttggacccaaggatgcttacctgtcagtgggacaccagcaccctcaagcaag
gaatgtagcagccctgagaaaaggctaagatccaagtcagtgcctgtgtcctgtgagatc
agctgtatggaactggcttcagactcagatgtgtgcacatcacctgtacaaggccttgaa
cccccggtgctggagtgtttggaaaaggaccatgtggagccagaacatgtgttgatagta
caacaggtgcttcaggagctgaggcagtatcatggggcccgtcagcgagctcgcatgtcc
accagccctggaggagcccactccaacctcacctggtttgagttcctgtctgagagcgag
gatggtgcgtgcaagattgagaagcccggcaagagcaccagagtgaagcgcagcctgagc
tccctccgcagcagggtcacgaggcagaaggagaaggggaagagtccagcacatctaaaa
gataagactcaggatcttccagggaagcgggagtgtgtcaatgggcaccagctgatgcga
ggaaccttctcgggccactccagctgtcctctgtgtggcgaacctttgctgaactcagcc
tccctgaaggagcaccctcggaccacacttctgtctgatggcagcagcccagctccttcc
aggaatgtcggcatgaccatctctcagaaagggggtctccagccaacaccgagcccagct
ggatctggggtgcgacttggaccaattgctggagacatggatgaagctgactccgtgttt
ttaaagttgaagcagacggcagacgactctctgtcactcacatcctcgaatgctgagtct
gttttcatagaagacccttacattgcttcactgaggtgtgagatcgaatcagatgcacat
gagtttgaggccgagtcctggagcctctctgtggatttagcatatgccaagaaacagaag
aaggaggtggtaaagagacaggacgtcctatatgagctgatgcagacagaggctcatcac
gtgcgcacactaaagatcatgctgaaagtatactccagagccctgcaggaagagctgcaa
ttcagtggccaggcagtcagccgtctgtttccgtgcgctgatgacttactggacatgcac
agccatttccttgcccgccttaaggagcgccggcaggagttcctagaggagggcagtgat
cggaattacgtcatccaaaagatcggagacgtcctggttcagcagttctcaggagaaacc
ggggagagaatgaaggagaaatacgctgtgttctgtagtggccacaatgatgcagtcggt
cagtacaagctattgctgcagcaaagcaagaagtttcaaaacttaatcaagaaaattggc
aacttttccattgtgcgaaggctgggagtgcaggagtgcatccttctggtcacacagcgc
ataaccaagtacccggtgcttgtggaacgcatcatccagaacacagaagctggcactgag
gactacaaggacctgagccaagccctgagcctcatcaaagacatcatctcacaagtggac
gccaaagtcagtgagtatgagaaggaccagcgcctcaaggagattgcagccaagacggac
cagaagtcgtctggcaaactcaaaaacgggctaaccttccgaaaggaggacatgctgcag
cagcgccagctccacctggaaggcgccctctgctggaagtccacctcagggcgcctgaaa
gatgtcctcgctgtcctgctgaccgatgtgcttttgctgctgcaagaaaaagatcagaaa
tatgtctttgcttctgtggactcaaagccacccgtcatctctctgcaaaagctcatcgtg
agagaggtagccaacgaggagaaggccatgttcctgatcagcgcctccatgcaggggcca
gagatgtatgagatgtacaccagctccaaagaggacaggaacatctggatggcccacatc
cgccgggccgtggagagctgtcctgacgaggaggaggacgttttcagtgaggctgaggag
aaaaagatagctgaagcccgcaccatgaaactccaggaatttcaagagcgactgagcctg
aaagaccagctgattgcccagagccttctggagaaacagcagatctacctggagatggct
cagctgagtgggctggaagagtcagcccagaaccgaggcctcttccgaggaggaggagac
ccctctgagaccctgcggggggagcagattctcagatcggccatgagtgagattgagggc
atccagagcctgatctgccagcggcacctgggcagcaccagtagccaagtggaggaggga
agtgtctctgcaggcctgcctcggcgggctgagaccttcgggggctatgacagtgtggga
agccctagcaagggtggcagctttaaaaggaaggtatccaacagtgacctcaggccccaa
gactggcagggacctgctagcagcccagactccaggccctgtgacaacagcgcccccagt
ggctgctgtgaggaatcgccacaggctgtggagatgcctagcacagagagcctgcccact
gtcctggaattagagctggtccaccgggtccagacactgtcgcagttgcttcttagtctc
caggcggtcatcgctcaacaggatagctatgtggagatgcaaagaacggccatccaggag
cgcgagaagcagttccggctgcagtcaacacgtgggaacctgctgctggagcaagagcgg
caacgcaactttgagaagcagcgtgaggagcgcgccggtgtggagaagctgcaaagccaa
cttcgccaggagcagcagcgatgggagcgggagcgggcacgccagcagcaggaactggag
ctggccggtgcgcgactgcaggagcgagagggcgaggcacgccagatgcgccagcggctg
gaccaggagcgcaccgagctagagcgacagcgccaggcctaccagcatgacctggagcgt
ctgcgtgaggcccagcgagcagtggaccgtgaacgtgagcgcctggagctgctgcgcagg
ttcaagaaacagaacactgtaccaggggcactgcccccggaggtgctggcagaggcccaa
cctgcaagccaccctcccagcttcaatggcgatgggctggaggggcactcggccccagcc
aaagcaccaggaacccaagggagcgcgatgctacatggcacaggacctgacaacgtagag
cgacccgaggtggcccgctgggacagtgccccccctgagagccggccagccaagagcgat
gtgcccatccagctactcagtgccaccaatcagattcagaggcagacagccgtgcaacag
cagatccccaccaagctggccgcctccaccaagggtggcaaggagaagggcagcaagagc
aggggttcccagcgttgggagagctcagcgtccttcgacctgaagcagcagctgctcctc
agcaagttcataggcaaggatgagagtgcatcacggaaccgccgttcactgagtcccgtc
ctgcctgccgcccatgggtctgcacctgcctcagacccctgcttcccagccccaagcccg
gccccagctgccacaccccccgaggccttcaagttcggaggcacatcactaccacctgtc
tccccagcttcctcgctgccaaccacaccactcgccaccacagatgaagttagtaaggaa
gatgtcatcttcttctga

  All links  
Gene (23)   
   RefGene (18)   
   NCBI-PROTEINID (1)   
   NCBI-Gene (1)   
   Ensembl (1)   
   RIKEN BRC-DNA (1)   
   OC (1)   
Protein sequence (13)   
   UniProt (1)   
   SWISS-PROT (1)   
   RefSeq(pep) (11)   
DNA sequence (46)   
   RefSeq(nuc) (12)   
   GenBank (17)   
   EMBL (17)   
3D Structure (1)   
   PDB (1)   
Protein domain (7)   
   Pfam (7)   
All databases (90)   

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