KEGG   Mus musculus (mouse): 104111Help
Entry
104111            CDS       T01002                                 

Gene name
Adcy3, AC3, ACIII, mKIAA0511
Definition
(RefSeq) adenylate cyclase 3
  KO
K08043  adenylate cyclase 3 [EC:4.6.1.1]
Organism
mmu  Mus musculus (mouse)
Pathway
mmu00230  Purine metabolism
mmu01100  Metabolic pathways
mmu01522  Endocrine resistance
mmu04015  Rap1 signaling pathway
mmu04020  Calcium signaling pathway
mmu04022  cGMP-PKG signaling pathway
mmu04024  cAMP signaling pathway
mmu04062  Chemokine signaling pathway
mmu04072  Phospholipase D signaling pathway
mmu04114  Oocyte meiosis
mmu04211  Longevity regulating pathway
mmu04213  Longevity regulating pathway - multiple species
mmu04261  Adrenergic signaling in cardiomyocytes
mmu04270  Vascular smooth muscle contraction
mmu04371  Apelin signaling pathway
mmu04540  Gap junction
mmu04611  Platelet activation
mmu04713  Circadian entrainment
mmu04714  Thermogenesis
mmu04723  Retrograde endocannabinoid signaling
mmu04724  Glutamatergic synapse
mmu04725  Cholinergic synapse
mmu04727  GABAergic synapse
mmu04740  Olfactory transduction
mmu04750  Inflammatory mediator regulation of TRP channels
mmu04911  Insulin secretion
mmu04912  GnRH signaling pathway
mmu04913  Ovarian steroidogenesis
mmu04914  Progesterone-mediated oocyte maturation
mmu04915  Estrogen signaling pathway
mmu04916  Melanogenesis
mmu04918  Thyroid hormone synthesis
mmu04921  Oxytocin signaling pathway
mmu04923  Regulation of lipolysis in adipocytes
mmu04925  Aldosterone synthesis and secretion
mmu04926  Relaxin signaling pathway
mmu04927  Cortisol synthesis and secretion
mmu04928  Parathyroid hormone synthesis, secretion and action
mmu04934  Cushing syndrome
mmu04935  Growth hormone synthesis, secretion and action
mmu04962  Vasopressin-regulated water reabsorption
mmu04970  Salivary secretion
mmu04971  Gastric acid secretion
mmu04972  Pancreatic secretion
mmu04976  Bile secretion
mmu05032  Morphine addiction
mmu05163  Human cytomegalovirus infection
mmu05166  Human T-cell leukemia virus 1 infection
mmu05200  Pathways in cancer
mmu05414  Dilated cardiomyopathy (DCM)
Brite
KEGG Orthology (KO) [BR:mmu00001]
 09100 Metabolism
  09104 Nucleotide metabolism
   00230 Purine metabolism
    104111 (Adcy3)
 09130 Environmental Information Processing
  09132 Signal transduction
   04015 Rap1 signaling pathway
    104111 (Adcy3)
   04371 Apelin signaling pathway
    104111 (Adcy3)
   04020 Calcium signaling pathway
    104111 (Adcy3)
   04072 Phospholipase D signaling pathway
    104111 (Adcy3)
   04024 cAMP signaling pathway
    104111 (Adcy3)
   04022 cGMP-PKG signaling pathway
    104111 (Adcy3)
 09140 Cellular Processes
  09143 Cell growth and death
   04114 Oocyte meiosis
    104111 (Adcy3)
  09144 Cellular community - eukaryotes
   04540 Gap junction
    104111 (Adcy3)
 09150 Organismal Systems
  09151 Immune system
   04611 Platelet activation
    104111 (Adcy3)
   04062 Chemokine signaling pathway
    104111 (Adcy3)
  09152 Endocrine system
   04911 Insulin secretion
    104111 (Adcy3)
   04923 Regulation of lipolysis in adipocytes
    104111 (Adcy3)
   04912 GnRH signaling pathway
    104111 (Adcy3)
   04913 Ovarian steroidogenesis
    104111 (Adcy3)
   04915 Estrogen signaling pathway
    104111 (Adcy3)
   04914 Progesterone-mediated oocyte maturation
    104111 (Adcy3)
   04921 Oxytocin signaling pathway
    104111 (Adcy3)
   04926 Relaxin signaling pathway
    104111 (Adcy3)
   04935 Growth hormone synthesis, secretion and action
    104111 (Adcy3)
   04918 Thyroid hormone synthesis
    104111 (Adcy3)
   04928 Parathyroid hormone synthesis, secretion and action
    104111 (Adcy3)
   04916 Melanogenesis
    104111 (Adcy3)
   04925 Aldosterone synthesis and secretion
    104111 (Adcy3)
   04927 Cortisol synthesis and secretion
    104111 (Adcy3)
  09153 Circulatory system
   04261 Adrenergic signaling in cardiomyocytes
    104111 (Adcy3)
   04270 Vascular smooth muscle contraction
    104111 (Adcy3)
  09154 Digestive system
   04970 Salivary secretion
    104111 (Adcy3)
   04971 Gastric acid secretion
    104111 (Adcy3)
   04972 Pancreatic secretion
    104111 (Adcy3)
   04976 Bile secretion
    104111 (Adcy3)
  09155 Excretory system
   04962 Vasopressin-regulated water reabsorption
    104111 (Adcy3)
  09156 Nervous system
   04724 Glutamatergic synapse
    104111 (Adcy3)
   04727 GABAergic synapse
    104111 (Adcy3)
   04725 Cholinergic synapse
    104111 (Adcy3)
   04723 Retrograde endocannabinoid signaling
    104111 (Adcy3)
  09157 Sensory system
   04740 Olfactory transduction
    104111 (Adcy3)
   04750 Inflammatory mediator regulation of TRP channels
    104111 (Adcy3)
  09149 Aging
   04211 Longevity regulating pathway
    104111 (Adcy3)
   04213 Longevity regulating pathway - multiple species
    104111 (Adcy3)
  09159 Environmental adaptation
   04713 Circadian entrainment
    104111 (Adcy3)
   04714 Thermogenesis
    104111 (Adcy3)
 09160 Human Diseases
  09161 Cancer: overview
   05200 Pathways in cancer
    104111 (Adcy3)
  09165 Substance dependence
   05032 Morphine addiction
    104111 (Adcy3)
  09166 Cardiovascular disease
   05414 Dilated cardiomyopathy (DCM)
    104111 (Adcy3)
  09167 Endocrine and metabolic disease
   04934 Cushing syndrome
    104111 (Adcy3)
  09172 Infectious disease: viral
   05166 Human T-cell leukemia virus 1 infection
    104111 (Adcy3)
   05163 Human cytomegalovirus infection
    104111 (Adcy3)
  09176 Drug resistance: antineoplastic
   01522 Endocrine resistance
    104111 (Adcy3)
Enzymes [BR:mmu01000]
 4. Lyases
  4.6  Phosphorus-oxygen lyases
   4.6.1  Phosphorus-oxygen lyases (only sub-subclass identified to date)
    4.6.1.1  adenylate cyclase
     104111 (Adcy3)
BRITE hierarchy
SSDB OrthologParalogGFIT
Motif
Pfam: Guanylate_cyc AC_N HNOBA Peptidase_S49_N fn3_4 NCE101
Motif
Other DBs
NCBI-GeneID: 104111
NCBI-ProteinID: NP_612178
MGI: 99675
Ensembl: ENSMUSG00000020654
Vega: OTTMUSG00000033731
UniProt: Q8VHH7 Q80TY9
Position
12; 12 A1.1
AA seq 1145 aa AA seqDB search
MPRNQGFSDPEYSAEYSAEYSVSLPSDPDRGVGRTHEISVRNSGSCLCLPRFMRLTFVPE
SLENLYQTYFKRQRHETLLVLVVFAALFDCYVVVMCAVVFSSDKLAPLMVAGFGLVLDII
LFVLCKKGLLPDRVSRKVVPYLLWLLISAQIFSYLGLNFSRAHAASDTVGWQAFFVFSFF
ITLPLSLSPIVIISVVSCVVHTLVLGVTVAQQQQDELEGMQLLREILANVFLYLCAIIVG
IMSYYMADRKHRKAFLEARQSLEVKMNLEEQSQQQENLMLSILPKHVADEMLKDMKKDES
QKDQQQFNTMYMYRHENVSILFADIVGFTQLSSACSAQELVKLLNELFARFDKLAAKYHQ
LRIKILGDCYYCICGLPDYREDHAVCSILMGLAMVEAISYVREKTKTGVDMRVGVHTGTV
LGGVLGQKRWQYDVWSTDVTVANKMEAGGIPGRVHISQSTMDCLKGEFDVEPGDGGSRCD
YLDEKGIETYLIIASKPEVKKTAQNGLNGSAVPNGAPASSKPSSPALIETKEPNGSAHAS
GSTSEEAEEQEAQADNPSFPNPRRRLRLQDLADRVVDASEDEHELNQLLNEALLERESAQ
VVKKRNTFLLTMRFMDPEMETRYSVEKEKQSGAAFSCSCVVLFCTAMVEILIDPWLMTNY
VTFVVGEVLLLILTICSMAAIFPRSFPKKLVAFSSWIDRTRWARNTWAMLAIFILVMANV
VDMLSCLQYYMGPYNMTAGMELDGGCMENPKYYNYVAVLSLIATIMLVQVSHMVKLTLML
LVTGAVTALNLYAWCPVFDEYDHKRFQEKDSPMVALEKMQVLATPGLNGTDSRLPLVPSK
YSMTVMMFVMMLSFYYFSRHVEKLARTLFLWKIEVHDQKERVYEMRRWNEALVTNMLPEH
VARHFLGSKKRDEELYSQSYDEIGVMFASLPNFADFYTEESINNGGIECLRFLNEIISDF
DSLLDNPKFRVITKIKTIGSTYMAASGVTPDVNTNGFTSSSKEEKSDKERWQHLADLADF
ALAMKDTLTNINNQSFNNFMLRIGMNKGGVLAGVIGARKPHYDIWGNTVNVASRMESTGV
MGNIQVVEETQVILREYGFRFVRRGPIFVKGKGELLTFFLKGRDRPAAFPNGSSVTLPHQ
VVDNP
NT seq 3438 nt NT seq  +upstreamnt  +downstreamnt
atgccgaggaaccagggcttctcggatcccgagtactcggcagagtactcagctgaatac
tcggtcagcctgccctctgaccccgaccgcggggtcggccggacccatgaaatttctgtg
cggaactcggggtcctgcctgtgcctgcctcgctttatgcggctgaccttcgtgcctgag
tccttggagaacctctaccagacctacttcaaaaggcagcgccatgagaccctgctggtg
ctggtggtctttgcggccctctttgactgctacgtggtagtgatgtgcgcggtggtcttc
tccagcgacaagctggcgcccctcatggtggcaggcttcggtctggtgttggacatcatc
cttttcgtgctctgtaaaaaggggctgctcccggaccgagtgagccgcaaagtggtaccc
tacctgctgtggctgctcatctcggcccagatcttctcctacctgggcctgaacttttca
cgggcccacgcagccagtgacactgtgggttggcaggctttctttgtcttctccttcttc
ataacgctgcccctcagcctcagccccatcgtgatcatctctgtggtctcctgtgttgtg
cacacgcttgtgttgggggtcactgtggcccagcagcagcaggatgagctggaagggatg
cagctgctgagggagatcctggccaacgtcttcctctacctgtgtgctatcatcgtgggc
atcatgtcctactacatggcagaccgcaagcaccgcaaggccttcctggaggcccgccag
tcactggaggtgaagatgaatctggaggagcagagccagcagcaggaaaaccttatgctt
tccatcctgcccaagcacgtggctgacgagatgctgaaggacatgaagaaggacgagagc
cagaaggaccagcagcagttcaataccatgtacatgtaccggcacgagaatgtcagcatc
ctgtttgcagatattgtgggctttacccagctgtcctctgcttgcagtgcccaggagctc
gtgaagttactcaacgagctcttcgcccgctttgacaagctggcagccaaataccaccag
ctgaggatcaagatcctaggcgactgttactactgcatctgcggcttgcctgactaccgg
gaggaccatgccgtgtgctccatccttatggggcttgccatggtagaggccatctcgtac
gtgcgggagaagaccaagactggagtggacatgcgtgtgggagtgcacacaggcactgtc
ctaggcggtgtcctgggccagaagcgctggcagtatgatgtatggtctactgatgtcacc
gtggcaaacaagatggaggctggtggcatcccagggcgcgtgcacatttcccagagcacc
atggactgcctgaagggggagtttgatgtggagcctggtgatgggggcagtcgctgcgac
tacctagatgagaagggcatcgaaacctacctcatcattgcctccaagccagaggtgaag
aaaacagcccaaaatggcctcaacggctcggccgtgccaaacggagcgccggcatcctcc
aaacccagctcccctgccctcatcgagaccaaggagcccaatggaagtgcccatgccagc
ggctccacatcagaggaggctgaagaacaggaggcccaggctgacaacccctcgttcccc
aacccccgccgcaggctgcgcctccaggacctggcggaccgtgtggtggacgcctctgag
gatgagcacgaactgaaccagctgcttaatgaggccctgctggagcgggagtccgcccag
gtggtaaagaagagaaacacattcctcctgaccatgaggttcatggacccagagatggaa
acacgctactcggtggagaaggagaagcagagcggggctgccttcagctgctcctgtgtg
gtcctcttctgcacggccatggtggagatactcattgacccctggctgatgacaaactat
gtgacctttgtggttggggaggttctgctcctgatcctgaccatctgctcgatggctgcc
atctttcccaggtcatttcccaagaagcttgtggccttctcatcttggattgaccggacc
cgctgggcaaggaacacctgggccatgttagccatcttcattctggttatggccaatgtt
gtggacatgctcagctgtctccagtactacatgggaccttacaacatgacagctgggatg
gagctggacggcggctgcatggagaaccccaagtactacaactacgtagctgtgctgtcg
ctcatcgccaccatcatgctggtgcaggtcagccacatggtgaagctgacgctcatgctg
ctcgtcacaggcgccgtgactgccctcaacctgtacgcctggtgtcctgtctttgatgaa
tacgaccacaagcgctttcaggaaaaggactctcctatggtggccttagagaagatgcag
gtacttgccacccctgggctcaatggcactgacagcaggctgcccctggtgccttccaag
tactccatgactgtgatgatgttcgtcatgatgctgagcttttactacttctcgcgccac
gtggaaaaactggcccgaacactgttcttgtggaagattgaggtccatgaccagaaagaa
cgtgtctacgagatgcgccgatggaacgaggccttggtcaccaacatgttgcctgagcat
gttgcacgccattttctggggtccaagaagagagatgaggagctgtacagccagtcttat
gacgagattggagtcatgtttgcctccttgcccaactttgctgacttctacactgaggag
agcatcaacaacggcggcatcgagtgtctacgcttcctcaatgagatcatctctgatttt
gactctctcctggacaatcccaaattccgggtcatcaccaagatcaaaactattggcagc
acctatatggcagcttcaggagtcacaccagatgtcaacaccaatggctttacaagctcc
agcaaggaggagaagtcagacaaggagcgctggcagcacctggctgacctggctgacttt
gcattagccatgaaggacacgctcacaaacatcaacaaccagtcattcaacaacttcatg
ttgcgcataggcatgaacaaaggaggggttctggctggcgtcattggagcccggaaacca
cactatgacatctggggcaatacggtcaatgtggccagcaggatggaatccacaggagtc
atgggcaacatccaggtggtagaagagacgcaggtcatccttcgagagtacggcttccgc
tttgtgaggcgaggtcccatctttgtgaaaggcaaaggggagcttctgacctttttcttg
aaggggcgggacaggccagctgccttccccaatggctcctctgttacactgccccaccaa
gtggtggacaacccctga

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