KEGG   Mus musculus (house mouse): 105148
Entry
105148            CDS       T01002                                 
Symbol
Iars1, 2510016L12Rik, E430001P04Rik, ILRS, Iars
Name
(RefSeq) isoleucyl-tRNA synthetase 1
  KO
K01870  isoleucyl-tRNA synthetase [EC:6.1.1.5]
Organism
mmu  Mus musculus (house mouse)
Pathway
mmu00970  Aminoacyl-tRNA biosynthesis
Brite
KEGG Orthology (KO) [BR:mmu00001]
 09120 Genetic Information Processing
  09122 Translation
   00970 Aminoacyl-tRNA biosynthesis
    105148 (Iars1)
 09180 Brite Hierarchies
  09181 Protein families: metabolism
   01007 Amino acid related enzymes [BR:mmu01007]
    105148 (Iars1)
  09182 Protein families: genetic information processing
   03016 Transfer RNA biogenesis [BR:mmu03016]
    105148 (Iars1)
Enzymes [BR:mmu01000]
 6. Ligases
  6.1  Forming carbon-oxygen bonds
   6.1.1  Ligases forming aminoacyl-tRNA and related compounds
    6.1.1.5  isoleucine---tRNA ligase
     105148 (Iars1)
Amino acid related enzymes [BR:mmu01007]
 Aminoacyl-tRNA synthetase
  Class I (U)
   105148 (Iars1)
Transfer RNA biogenesis [BR:mmu03016]
 Eukaryotic type
  Aminoacyl-tRNA synthetases (AARSs)
   Multi-aminoacyl-tRNA synthetase complex (MSC)
    105148 (Iars1)
 Prokaryotic type
   Other AARSs
    105148 (Iars1)
SSDB
Motif
Pfam: tRNA-synt_1 Anticodon_1 DUF5915 tRNA-synt_1g tRNA-synt_1e
Other DBs
NCBI-GeneID: 105148
NCBI-ProteinID: NP_742012
MGI: 2145219
Ensembl: ENSMUSG00000037851
UniProt: Q8BU30
Position
13:49835606..49887743
AA seq 1262 aa
MVQQVPENISFPAEEEKILEFWSKHNCFQECLKQSKLRPKFTFYDGPPFATGLPHYGHIL
AGTIKDIVTRYAHQSGFHVDRRFGWDCHGLPVEYEIDKTLGIKGPEDVAKMGIAEYNKQC
RAIVMRYSAEWKSTVTRLGRWIDFDNDYKTLYPQFMESVWWVFKQLYDKGLVYRGVKVMP
FSTACGTPLSNFESNQNYKDVQDPSVFVTFPLEEDENTSLVAWTTTPWTLPSNLALCVNP
EIQYVKIKDVARGKLFILTEARLSALYKQESDYEILERFPGASLKGKKYKPLFDYFIKCK
ENGAFTVLVDHYVKDEEGTGVVHQAPYFGADDHRVCMDFNIIQKDSVPVCPVDASGCFTE
EVTHFVGQYVKDADKNIIRMLKEQGRLLAAGTFTHSYPFCWRSDTPLIYKSVPSWFVRVE
PMVDQLLKNNDLCYWVPEFVREKRFGNWLKEARDWAISRNRYWGTPIPLWVSEDLEEVVC
IGSVAELEELSGTKISDLHRESIDHLTIPSRCGKAPLRRVSEVFDCWFESGSMPYAQVHY
PFESKREFEDAFPADFIAEGIDQTRGWFYTLLVLATALFGQPPFKNVIVNGLILASDGQK
MSKRKKNYPDPVSIIDKYGADALRLYLINSPVVRAENLRFKEEGVRDVLKDVLLPWYNAY
RFFIQNVFRLHKEEEVKFLYNEHTVRESPNITDRWVLSFMQSLLGFFETEMAAYRLYTVV
PRLVKFVDILTNWYVRMNRRRLKGESGVEDCVMALETLFSVLLSLCRLMAPYTPFLTELM
YQNLKLLIDPASLRDKDTLSIHYLMLPRVREELIDKKTENAVSRMQSVIELGRVIRDRKT
IPIKYPLKEIVVIHQDPEALEDIRSLEKYIIEELNVRKVTLSTDKNKYGIRLRAEPDHMV
LGKRLKGAFKAVMMAIKRLSNEELERFQKSGSIVVEGHELHEEDIRLMYTFDQATGGTAQ
FEAHSDAQALVLLDVTPDQSMVDEGMAREVINRIQKLRKKCNLVPTDEITVYYNAKSEGR
YLNNVIESHTDFIFATIKAPLKPYPVPTSDNILIQEQTQLKGSELEITLTKGSCVPGPAC
AYVNLNICANGTEQGGVLLLENPKGDNQLNLVKLKTVVTSVFGVKNAKLSVFHGETEIQN
QTDLLSLSGRTLCVTAGASPSPISSPSTLLCQYLNLQLLNAEPQECLTGTVGTLLLENPL
GQNGLTHQGLVHEAAKVFGLRSRRLRLFLNETQTQEITEDIPMKTLNMKTVYVSVLPTTA
DG
NT seq 3789 nt   +upstreamnt  +downstreamnt
atggttcaacaagttccagaaaacatcagttttcctgctgaagaagaaaaaatcttggag
ttctggtccaaacataactgtttccaggaatgcctcaaacagtcaaaactcaggccaaag
tttaccttctatgatgggcctccctttgctactggactgcctcactatggacacatactt
gctgggacaatcaaagatatcgttacgagatacgctcaccagagcgggtttcacgttgac
agaagattcgggtgggactgtcacggcttacctgtggagtacgaaatcgataagacactg
ggcatcaaaggcccggaggatgtggccaaaatggggattgcagagtacaacaagcagtgc
cgagcaatcgtgatgagatactccgctgagtggaagtctactgttaccagactcggccga
tggatcgactttgacaatgactacaaaacactatacccacagttcatggaatcagtctgg
tgggtcttcaagcagctgtatgacaaaggcctcgtgtacagaggcgtgaaggtcatgccc
ttctccaccgcgtgtggcactccactctccaacttcgaatctaaccagaattacaaggat
gttcaggatccctcagtatttgtaacattccctttggaggaagatgaaaatacatcctta
gttgcttggacaaccactccttggactctacccagtaaccttgcactatgcgtcaatcca
gaaatacagtatgtgaagatcaaagatgtggccaggggaaaattattcatcttaacggaa
gccagattatcggccctctataagcaagagagcgactatgagatacttgaaaggtttcct
ggtgcctctctcaaaggcaagaaatacaagccgttgtttgactactttattaagtgtaag
gagaacggtgccttcaccgtgcttgtcgaccactatgtgaaggatgaagaaggcacaggc
gttgtgcaccaggctccttactttggtgctgatgatcatcgtgtctgtatggacttcaac
attattcagaaagactcagtccctgtttgtcctgtggatgcttcaggctgcttcacagag
gaagtgacacattttgtggggcagtatgtgaaggatgctgacaaaaatatcattaggatg
ttgaaggagcagggccggctgctggcggcgggcacgttcactcacagctaccctttctgc
tggaggtcagacacgcccctcatttacaagtctgtgcccagctggtttgtgcgggtggag
cccatggtggaccagctactgaagaacaacgacctgtgctactgggtcccagagtttgta
cgagaaaaacggtttggaaattggctgaaggaggcccgtgactgggcaatttccagaaac
agatactggggcacccccatcccactgtgggtcagcgaagacttggaggaggtagtgtgc
attggatcagtggcagagcttgaagaactgtcgggaacaaaaatctcagatctccacaga
gagagcatcgaccacctgaccatcccatcccgctgcgggaaagcaccattgcggcgcgtc
tctgaggtgtttgactgctggttcgagagtggaagtatgccctatgcccaggtccattat
ccgttcgagagcaagcgcgagtttgaggatgcctttcctgcagacttcattgctgaaggc
atcgatcaaaccagaggatggttttacaccctgctggtgctagccacagcgctctttgga
cagccacctttcaagaatgtgattgtgaatggcctcatcttggcaagtgatggccaaaaa
atgagcaagcggaaaaagaactacccagatccagtttccatcatcgataagtatggtgcg
gacgccctcaggttatatctgatcaattcccctgtggtaagagcagaaaacctgcgcttc
aaggaggaaggtgtgcgggatgtcctcaaagatgtgctgctcccgtggtacaacgcttac
cgcttcttcatccagaacgtctttaggctccacaaggaagaagaagtgaagttcctatac
aacgagcatacagtcagagaaagccctaacatcaccgaccgctgggttctgtccttcatg
cagtcgctccttggcttctttgagaccgaaatggcagcttacaggctgtacactgtggta
cctcgcctggtcaagtttgtagatattctaaccaactggtatgtccgaatgaacaggagg
aggttaaagggtgagagtggggtggaagactgtgtcatggctctggagacactgttcagt
gtcctgctttctctgtgcagactgatggccccttacacgccctttctgactgagctgatg
taccagaatctaaagctgctgattgatcctgcttctctccgggacaaggacacactcagc
atccactacctcatgctgcctcgagttcgagaggagctgattgacaagaaaactgagaac
gccgtgtctaggatgcagtctgtgatcgagcttggaagagtgatacgagaccgaaaaact
attccaataaagtatcctctgaaggaaattgtggtcatccaccaagacccagaagctcta
gaggatatcaggtccttggagaagtatatcattgaggaattaaatgttcgaaaagtcacg
ctgtctactgataaaaacaagtacggtatccgactaagggctgaaccagatcacatggtc
cttgggaagcgcctgaagggggccttcaaagcggtgatgatggccataaagcggctgagc
aatgaggagctggagcggtttcagaagagcgggagcattgttgtggaaggccacgaactg
catgaggaagacattcgcctcatgtacacctttgaccaggccacgggagggaccgcgcag
tttgaagcacactctgatgctcaggctctagttctcttagatgtcacacctgaccagtca
atggtggatgagggcatggctcgggaagtcatcaatcgcatccagaagcttcgaaagaag
tgcaatctggttccaacggatgaaataacagtttactataatgcaaaatctgaaggaaga
tacttgaataatgtcattgaaagccacactgacttcatatttgccacaatcaaagctccc
ttgaagccatatccagttccaacatcagataatatccttattcaagagcaaacacagtta
aaggggtccgagctggaaatcacgctcaccaaaggatcgtgtgtgcctggccctgcttgt
gcttatgtgaaccttaacatttgtgcaaatggcaccgagcaaggtggagtgttgctcctg
gagaatccgaaaggtgataatcagctgaacctggtgaaactgaagactgttgttaccagc
gtatttggtgttaaaaatgcaaagctgtcagtcttccacggtgaaacagaaatacagaac
caaactgacttgctgagcctcagtgggaggacgctgtgtgtgactgcaggggcatccccg
tctcccatcagcagccccagcaccctgctgtgtcagtacctcaacctgcagctcctgaac
gcagagccacaagagtgtttaacaggaactgtgggcaccctcctgcttgaaaacccactc
ggacagaacggcctcacccaccaagggcttgtgcatgaagcagccaaggtgttcggactg
aggagcaggaggctaaggctgttcctgaatgagactcaaacacaagaaattacagaagat
atcccaatgaagactttgaatatgaagactgtatatgtttctgtcttgccaacaactgca
gatggctaa

  All links  
Ontology (4)   
   KEGG BRITE (4)   
Pathway (1)   
   KEGG PATHWAY (1)   
Chemical substance (6)   
   KEGG COMPOUND (6)   
Chemical reaction (2)   
   KEGG ENZYME (1)   
   KEGG REACTION (1)   
Genome (1)   
   KEGG GENOME (1)   
Gene (21)   
   KEGG ORTHOLOGY (1)   
   KEGG GENES (1)   
   RefGene (14)   
   NCBI-PROTEINID (1)   
   NCBI-Gene (1)   
   Ensembl (1)   
   RIKEN BRC-DNA (1)   
   OC (1)   
Protein sequence (4)   
   UniProt (1)   
   SWISS-PROT (1)   
   RefSeq(pep) (2)   
DNA sequence (18)   
   RefSeq(nuc) (2)   
   GenBank (8)   
   EMBL (8)   
Protein domain (5)   
   Pfam (5)   
All databases (62)   

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