KEGG   Mus musculus (mouse): 105148
Entry
105148            CDS       T01002                                 

Gene name
Iars, 2510016L12Rik, AI327140, AU044614, E430001P04Rik, ILRS, Iars1
Definition
(RefSeq) isoleucine-tRNA synthetase
  KO
K01870  isoleucyl-tRNA synthetase [EC:6.1.1.5]
Organism
mmu  Mus musculus (mouse)
Pathway
mmu00970  Aminoacyl-tRNA biosynthesis
Brite
KEGG Orthology (KO) [BR:mmu00001]
 09120 Genetic Information Processing
  09122 Translation
   00970 Aminoacyl-tRNA biosynthesis
    105148 (Iars)
 09180 Brite Hierarchies
  09181 Protein families: metabolism
   01007 Amino acid related enzymes [BR:mmu01007]
    105148 (Iars)
  09182 Protein families: genetic information processing
   03016 Transfer RNA biogenesis [BR:mmu03016]
    105148 (Iars)
Enzymes [BR:mmu01000]
 6. Ligases
  6.1  Forming carbon-oxygen bonds
   6.1.1  Ligases forming aminoacyl-tRNA and related compounds
    6.1.1.5  isoleucine---tRNA ligase
     105148 (Iars)
Amino acid related enzymes [BR:mmu01007]
 Aminoacyl-tRNA synthetase
  Class I (U)
   105148 (Iars)
Transfer RNA biogenesis [BR:mmu03016]
 Eukaryotic type
  Aminoacyl-tRNA synthetases (AARSs)
   Multi-aminoacyl-tRNA synthetase complex (MSC)
    105148 (Iars)
 Prokaryotic type
   Other AARSs
    105148 (Iars)
Motif
Pfam: tRNA-synt_1 Anticodon_1 tRNA-synt_1g tRNA-synt_1e
Other DBs
NCBI-GeneID: 105148
NCBI-ProteinID: NP_742012
MGI: 2145219
Ensembl: ENSMUSG00000037851
Vega: OTTMUSG00000035300
UniProt: Q8BU30
Position
13; 13 A5
AA seq 1262 aa
MVQQVPENISFPAEEEKILEFWSKHNCFQECLKQSKLRPKFTFYDGPPFATGLPHYGHIL
AGTIKDIVTRYAHQSGFHVDRRFGWDCHGLPVEYEIDKTLGIKGPEDVAKMGIAEYNKQC
RAIVMRYSAEWKSTVTRLGRWIDFDNDYKTLYPQFMESVWWVFKQLYDKGLVYRGVKVMP
FSTACGTPLSNFESNQNYKDVQDPSVFVTFPLEEDENTSLVAWTTTPWTLPSNLALCVNP
EIQYVKIKDVARGKLFILTEARLSALYKQESDYEILERFPGASLKGKKYKPLFDYFIKCK
ENGAFTVLVDHYVKDEEGTGVVHQAPYFGADDHRVCMDFNIIQKDSVPVCPVDASGCFTE
EVTHFVGQYVKDADKNIIRMLKEQGRLLAAGTFTHSYPFCWRSDTPLIYKSVPSWFVRVE
PMVDQLLKNNDLCYWVPEFVREKRFGNWLKEARDWAISRNRYWGTPIPLWVSEDLEEVVC
IGSVAELEELSGTKISDLHRESIDHLTIPSRCGKAPLRRVSEVFDCWFESGSMPYAQVHY
PFESKREFEDAFPADFIAEGIDQTRGWFYTLLVLATALFGQPPFKNVIVNGLILASDGQK
MSKRKKNYPDPVSIIDKYGADALRLYLINSPVVRAENLRFKEEGVRDVLKDVLLPWYNAY
RFFIQNVFRLHKEEEVKFLYNEHTVRESPNITDRWVLSFMQSLLGFFETEMAAYRLYTVV
PRLVKFVDILTNWYVRMNRRRLKGESGVEDCVMALETLFSVLLSLCRLMAPYTPFLTELM
YQNLKLLIDPASLRDKDTLSIHYLMLPRVREELIDKKTENAVSRMQSVIELGRVIRDRKT
IPIKYPLKEIVVIHQDPEALEDIRSLEKYIIEELNVRKVTLSTDKNKYGIRLRAEPDHMV
LGKRLKGAFKAVMMAIKRLSNEELERFQKSGSIVVEGHELHEEDIRLMYTFDQATGGTAQ
FEAHSDAQALVLLDVTPDQSMVDEGMAREVINRIQKLRKKCNLVPTDEITVYYNAKSEGR
YLNNVIESHTDFIFATIKAPLKPYPVPTSDNILIQEQTQLKGSELEITLTKGSCVPGPAC
AYVNLNICANGTEQGGVLLLENPKGDNQLNLVKLKTVVTSVFGVKNAKLSVFHGETEIQN
QTDLLSLSGRTLCVTAGASPSPISSPSTLLCQYLNLQLLNAEPQECLTGTVGTLLLENPL
GQNGLTHQGLVHEAAKVFGLRSRRLRLFLNETQTQEITEDIPMKTLNMKTVYVSVLPTTA
DG
NT seq 3789 nt   +upstreamnt  +downstreamnt
atggttcaacaagttccagaaaacatcagttttcctgctgaagaagaaaaaatcttggag
ttctggtccaaacataactgtttccaggaatgcctcaaacagtcaaaactcaggccaaag
tttaccttctatgatgggcctccctttgctactggactgcctcactatggacacatactt
gctgggacaatcaaagatatcgttacgagatacgctcaccagagcgggtttcacgttgac
agaagattcgggtgggactgtcacggcttacctgtggagtacgaaatcgataagacactg
ggcatcaaaggcccggaggatgtggccaaaatggggattgcagagtacaacaagcagtgc
cgagcaatcgtgatgagatactccgctgagtggaagtctactgttaccagactcggccga
tggatcgactttgacaatgactacaaaacactatacccacagttcatggaatcagtctgg
tgggtcttcaagcagctgtatgacaaaggcctcgtgtacagaggcgtgaaggtcatgccc
ttctccaccgcgtgtggcactccactctccaacttcgaatctaaccagaattacaaggat
gttcaggatccctcagtatttgtaacattccctttggaggaagatgaaaatacatcctta
gttgcttggacaaccactccttggactctacccagtaaccttgcactatgcgtcaatcca
gaaatacagtatgtgaagatcaaagatgtggccaggggaaaattattcatcttaacggaa
gccagattatcggccctctataagcaagagagcgactatgagatacttgaaaggtttcct
ggtgcctctctcaaaggcaagaaatacaagccgttgtttgactactttattaagtgtaag
gagaacggtgccttcaccgtgcttgtcgaccactatgtgaaggatgaagaaggcacaggc
gttgtgcaccaggctccttactttggtgctgatgatcatcgtgtctgtatggacttcaac
attattcagaaagactcagtccctgtttgtcctgtggatgcttcaggctgcttcacagag
gaagtgacacattttgtggggcagtatgtgaaggatgctgacaaaaatatcattaggatg
ttgaaggagcagggccggctgctggcggcgggcacgttcactcacagctaccctttctgc
tggaggtcagacacgcccctcatttacaagtctgtgcccagctggtttgtgcgggtggag
cccatggtggaccagctactgaagaacaacgacctgtgctactgggtcccagagtttgta
cgagaaaaacggtttggaaattggctgaaggaggcccgtgactgggcaatttccagaaac
agatactggggcacccccatcccactgtgggtcagcgaagacttggaggaggtagtgtgc
attggatcagtggcagagcttgaagaactgtcgggaacaaaaatctcagatctccacaga
gagagcatcgaccacctgaccatcccatcccgctgcgggaaagcaccattgcggcgcgtc
tctgaggtgtttgactgctggttcgagagtggaagtatgccctatgcccaggtccattat
ccgttcgagagcaagcgcgagtttgaggatgcctttcctgcagacttcattgctgaaggc
atcgatcaaaccagaggatggttttacaccctgctggtgctagccacagcgctctttgga
cagccacctttcaagaatgtgattgtgaatggcctcatcttggcaagtgatggccaaaaa
atgagcaagcggaaaaagaactacccagatccagtttccatcatcgataagtatggtgcg
gacgccctcaggttatatctgatcaattcccctgtggtaagagcagaaaacctgcgcttc
aaggaggaaggtgtgcgggatgtcctcaaagatgtgctgctcccgtggtacaacgcttac
cgcttcttcatccagaacgtctttaggctccacaaggaagaagaagtgaagttcctatac
aacgagcatacagtcagagaaagccctaacatcaccgaccgctgggttctgtccttcatg
cagtcgctccttggcttctttgagaccgaaatggcagcttacaggctgtacactgtggta
cctcgcctggtcaagtttgtagatattctaaccaactggtatgtccgaatgaacaggagg
aggttaaagggtgagagtggggtggaagactgtgtcatggctctggagacactgttcagt
gtcctgctttctctgtgcagactgatggccccttacacgccctttctgactgagctgatg
taccagaatctaaagctgctgattgatcctgcttctctccgggacaaggacacactcagc
atccactacctcatgctgcctcgagttcgagaggagctgattgacaagaaaactgagaac
gccgtgtctaggatgcagtctgtgatcgagcttggaagagtgatacgagaccgaaaaact
attccaataaagtatcctctgaaggaaattgtggtcatccaccaagacccagaagctcta
gaggatatcaggtccttggagaagtatatcattgaggaattaaatgttcgaaaagtcacg
ctgtctactgataaaaacaagtacggtatccgactaagggctgaaccagatcacatggtc
cttgggaagcgcctgaagggggccttcaaagcggtgatgatggccataaagcggctgagc
aatgaggagctggagcggtttcagaagagcgggagcattgttgtggaaggccacgaactg
catgaggaagacattcgcctcatgtacacctttgaccaggccacgggagggaccgcgcag
tttgaagcacactctgatgctcaggctctagttctcttagatgtcacacctgaccagtca
atggtggatgagggcatggctcgggaagtcatcaatcgcatccagaagcttcgaaagaag
tgcaatctggttccaacggatgaaataacagtttactataatgcaaaatctgaaggaaga
tacttgaataatgtcattgaaagccacactgacttcatatttgccacaatcaaagctccc
ttgaagccatatccagttccaacatcagataatatccttattcaagagcaaacacagtta
aaggggtccgagctggaaatcacgctcaccaaaggatcgtgtgtgcctggccctgcttgt
gcttatgtgaaccttaacatttgtgcaaatggcaccgagcaaggtggagtgttgctcctg
gagaatccgaaaggtgataatcagctgaacctggtgaaactgaagactgttgttaccagc
gtatttggtgttaaaaatgcaaagctgtcagtcttccacggtgaaacagaaatacagaac
caaactgacttgctgagcctcagtgggaggacgctgtgtgtgactgcaggggcatccccg
tctcccatcagcagccccagcaccctgctgtgtcagtacctcaacctgcagctcctgaac
gcagagccacaagagtgtttaacaggaactgtgggcaccctcctgcttgaaaacccactc
ggacagaacggcctcacccaccaagggcttgtgcatgaagcagccaaggtgttcggactg
aggagcaggaggctaaggctgttcctgaatgagactcaaacacaagaaattacagaagat
atcccaatgaagactttgaatatgaagactgtatatgtttctgtcttgccaacaactgca
gatggctaa

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