KEGG   Mus musculus (house mouse): 107823
Entry
107823            CDS       T01002                                 
Symbol
Nsd2, 5830445G22Rik, 9430010A17Rik, C130020C13Rik, D030027O06Rik, D930023B08Rik, MMSET, Whsc1, Whsc1l, mKIAA1090
Name
(RefSeq) nuclear receptor binding SET domain protein 2
  KO
K11424  [histone H3]-lysine36 N-dimethyltransferase NSD2 [EC:2.1.1.357]
Organism
mmu  Mus musculus (house mouse)
Pathway
mmu00310  Lysine degradation
mmu01100  Metabolic pathways
mmu05202  Transcriptional misregulation in cancer
Brite
KEGG Orthology (KO) [BR:mmu00001]
 09100 Metabolism
  09105 Amino acid metabolism
   00310 Lysine degradation
    107823 (Nsd2)
 09160 Human Diseases
  09161 Cancer: overview
   05202 Transcriptional misregulation in cancer
    107823 (Nsd2)
 09180 Brite Hierarchies
  09182 Protein families: genetic information processing
   03036 Chromosome and associated proteins [BR:mmu03036]
    107823 (Nsd2)
Enzymes [BR:mmu01000]
 2. Transferases
  2.1  Transferring one-carbon groups
   2.1.1  Methyltransferases
    2.1.1.357  [histone H3]-lysine36 N-dimethyltransferase
     107823 (Nsd2)
Chromosome and associated proteins [BR:mmu03036]
 Eukaryotic type
  Histone modification proteins
   HMTs (histone methyltransferases)
    HKMTs (histone lysine methyltransferases)
     107823 (Nsd2)
SSDB
Motif
Pfam: PWWP PHD-1st_NSD SET NSD_PHD AWS C5HCH HMG_box PHD PHDvar_NSD HMG_box_2 zf-HC5HC2H zf-HC5HC2H_2 MUM1-like_PWWP
Other DBs
NCBI-GeneID: 107823
NCBI-ProteinID: NP_780440
MGI: 1276574
Ensembl: ENSMUSG00000057406
UniProt: Q8BVE8
Position
5:33974286..34055310
AA seq 1365 aa
MEFSIRKSPLSVQKVVKCMKMKQTPEILGSANGKTQNCEVNHECSVFLSKAQLSNSLQEG
VMQKFNGHDALPFLPAEKLKDLTSCVFNGEPGAHDTKLCFEAQEVKGIGTPPNTTPIKNG
SPEIKLKITKTYMNGKPLFESSICGDGAADVSQSEENEQKSDNKTRRNRKRSIKYDSLLE
QGLVEAALVSKISSPADKKIPVKKESCPNTGRDRDLLLKYNVGDLVWSKVSGYPWWPCMV
SADPLLHNHTKLKGQKKSARQYHVQFFGDAPERAWIFEKSLVAFEGEEQFEKLCQESAKQ
APTKAEKIKLLKPISGRLRAQWEMGIVQAEEAASMSIEERKAKFTFLYVGDQLHLNPQVA
KEAGIVTEPLGEMVDSSGASEEAAVDPGSVREEDIPTKRRRRTKRSSSAENQEGDPGTDK
STPPKMAEAEPKRGVGSPAGRKKSTGSAPRSRKGDSAAQFLVFCQKHRDEVVAEHPDASG
EEIEELLGSQWSMLNEKQKARYNTKFSLMISAQSEEDSGNGNGKKRSHTKRADDPAEDVD
VEDAPRKRLRADKHSLRKRETITDKTARTSSYKAIEAASSLKSQAATKNLSDACKPLKKR
NRASATASSALGFNKSSSPSASLTEHEVSDSPGDEPSESPYESADETQTEASVSSKKSER
GMAAKKEYVCQLCEKTGSLLLCEGPCCGAFHLACLGLSRRPEGRFTCTECASGIHSCFVC
KESKMEVKRCVVNQCGKFYHEACVKKYPLTVFESRGFRCPLHSCMSCHASNPSNPRPSKG
KMMRCVRCPVAYHGGDACLAAGCSVIASNSIICTGHFTARKGKRHHTHVNVSWCFVCSKG
GSLLCCEACPAAFHPDCLNIEMPDGSWFCNDCRAGKKLHFQDIIWVKLGNYRWWPAEVCH
PKNVPPNIQKMKHEIGEFPVFFFGSKDYYWTHQARVFPYMEGDRGSRYQGVRGIGRVFKN
ALQEAEARFNEVKLQREARETQESERKPPPYKHIKVNKPYGKVQIYTADISEIPKCNCKP
TDENPCGSDSECLNRMLMFECHPQVCPAGEYCQNQCFTKRQYPETKIIKTDGKGWGLVAK
RDIRKGEFVNEYVGELIDEEECMARIKYAHENDITHFYMLTIDKDRIIDAGPKGNYSRFM
NHSCQPNCETLKWTVNGDTRVGLFAVCDIPAGTELTFNYNLDCLGNEKTVCRCGASNCSG
FLGDRPKTSASLSSEEKGKKAKKKTRRRRAKGEGKRQSEDECFRCGDGGQLVLCDRKFCT
KAYHLSCLGLGKRPFGKWECPWHHCDVCGKPSTSFCHLCPNSFCKEHQDGTAFRSTQDGQ
SYCCEHDLRADSSSSTKTEKPFPESLKSKGKRKKRRCWRRVTDGK
NT seq 4098 nt   +upstreamnt  +downstreamnt
atggaatttagcatcagaaaaagtcctctttctgttcagaaagttgtaaagtgcatgaag
atgaagcagacaccagaaatccttggcagtgcaaatggaaagactcagaactgtgaagtg
aatcatgaatgttctgtattcctcagcaaagctcaactttctaacagcctacaggagggg
gtcatgcagaaatttaatggccatgatgcgctcccctttcttccagcagagaagttgaaa
gatcttacttcttgtgtttttaatggagaacctggtgctcatgatactaaattgtgtttt
gaggcccaggaagtaaaaggaattgggacaccacccaatactacacctatcaaaaatggc
tctccagaaattaaactgaaaatcaccaaaacatacatgaatgggaaacctctctttgaa
tcttcaatttgtggtgacggtgctgctgatgtgtctcagtcagaagaaaacgaacaaaaa
tctgataataagactaggaggaacaggaagaggagcataaaatatgactctttactggag
cagggccttgtggaagcagctttagtgtccaagatctcaagtcctgcagataaaaagatt
ccagttaagaaggagtcctgtccaaatactggcagagacagagacctcttgttaaaatac
aacgttggtgatttggtgtggtccaaagtgtcaggttacccttggtggccttgcatggtt
tctgctgacccactccttcacaatcataccaaacttaaaggtcagaaaaaaagtgcacgc
cagtatcatgtacagttctttggtgatgccccagaaagagcttggatatttgagaagagc
cttgttgcttttgaaggagaagaacaatttgaaaaattatgccaagaaagtgccaagcag
gcacccacgaaagctgagaaaatcaagttgttgaaacctatttcggggagattgagagcc
cagtgggaaatgggcattgtccaagctgaggaagctgccagcatgtcaatagaggagcgg
aaagccaaatttaccttcctttatgtgggggaccaattgcacctcaaccctcaagtagct
aaggaggctggcattgttacagaacctttgggagaaatggtggactcttcaggggccagt
gaagaggctgctgtagaccctgggtctgtgagagaagaggatattcccacgaagagaagg
cgaagaaccaaaaggtctagttctgctgagaaccaagaaggtgatcctggcacagacaag
agtacacctccaaagatggcagaggctgaacctaagcgaggagtaggctctcctgctggg
aggaaaaagtccacaggctctgctcctcggagcaggaagggagactcagcagcccagttt
ttagtcttttgtcaaaaacacagagatgaggttgtagctgaacatccagatgcctcaggg
gaagagattgaagaattgcttgggtcccagtggagcatgctcaatgaaaagcagaaagca
cgatataatacaaagttttccctaatgatctctgcccagtctgaagaagactctggaaat
gggaatgggaaaaaaagaagccacacaaagagagcagatgaccctgcagaggatgtggat
gttgaagacgcgcccaggaaaagacttagagcagataagcacagtcttcggaagagagag
acaatcaccgacaaaacggccagaacaagctcttacaaggctatagaggcagcctcctca
ctcaagagccaggcagcaacgaaaaatttgtctgatgcttgcaaaccactgaagaagcga
aatcgggcttctgcaacagcgtcttcagcacttgggtttaacaaaagttcatctccttct
gcatccttaactgagcatgaggtctcagacagcccaggagatgaaccatcagagtctcca
tatgaaagtgcagatgaaacacagactgaagcatccgtctcatctaaaaaatctgaaaga
ggaatggctgccaaaaaggagtacgtgtgtcagctgtgtgagaagacaggcagtctctta
ctgtgtgagggcccctgttgtggagcattccacctagcctgccttggactttcccgaaga
ccggaaggaagattcacctgcaccgaatgtgcctcagggattcactcatgcttcgtatgt
aaagaaagcaagatggaggtgaaacgttgtgtggtaaatcagtgtggaaagttttaccat
gaagcctgtgtaaaaaaataccctctcactgtgtttgagagccgaggcttccgctgtcct
ctccatagctgtatgagctgccatgcctccaacccttcaaatccacggccatcaaaaggt
aaaatgatgcgatgtgtccgatgccccgttgcctatcatggaggggatgcctgtctggca
gcaggatgttcggtgattgcttctaacagcataatctgcacaggccacttcactgcccgg
aaggggaagcggcaccatacccatgtcaatgtgagctggtgctttgtgtgctccaaaggg
ggaagccttctgtgctgtgaggcctgcccagcagcctttcaccccgattgtctaaacatc
gagatgcccgatggtagctggttctgcaacgattgccgggctggaaagaagctccacttt
caagacatcatctgggtcaaacttggtaactacagatggtggccggcagaagtttgccat
cccaaaaatgttcccccaaatattcagaaaatgaagcacgagattggagaattccctgta
tttttctttgggtctaaagattattactggacgcatcaggcacgagtgttcccatacatg
gagggggaccggggcagccgctaccagggggtcagagggatcggaagagtcttcaagaac
gcattgcaagaagctgaagctcgttttaatgaagtcaaacttcagcgggaagcccgagaa
acacaggagagtgagagaaagcctccaccatacaagcatatcaaggtgaataaaccttat
ggtaaagtccagatctacacagctgacatttctgaaatcccgaagtgcaactgtaagccc
acagatgagaacccctgtggctctgattcagagtgtctgaacaggatgctaatgtttgag
tgccacccgcaggtgtgtcctgcaggggaatactgccagaaccagtgtttcactaagcgc
cagtaccctgagaccaagatcatcaagacagatggcaaagggtggggcctggttgccaaa
agggacatcagaaaaggagaatttgttaatgagtatgttggtgagctgattgatgaagag
gagtgtatggcaagaatcaaatatgcacatgagaatgacatcactcacttctacatgctc
accatagacaaggaccgcataattgatgctggccccaaagggaattattcacgattcatg
aaccatagctgccagcccaattgtgagaccctgaagtggacagtgaatggggacacacgg
gttggcctgtttgctgtgtgtgacattcctgcaggtacagagctgactttcaactataac
cttgattgtttgggcaatgaaaagacagtctgtcggtgtggagcctccaactgtagtggg
ttccttggagacagaccaaagacatcagcatccctttcatcagaggaaaagggtaaaaag
gccaagaagaaaaccagaaggcgcagagccaagggtgaaggaaaacggcagtcagaggat
gagtgcttccgctgtggtgatggtgggcagctggtgctgtgtgaccgcaagttctgtacc
aaggcctaccacctatcctgcctcggtttgggcaagcggccctttgggaagtgggaatgt
ccttggcatcactgtgatgtatgtggcaaaccttctacctcattttgccacctctgcccc
aactcattctgtaaggaacaccaagatgggactgctttccgttccacccaggatgggcag
tcctactgctgtgagcatgacttgagggcagactcttcaagtagcaccaagactgagaaa
ccctttccagaatcactgaagtcaaaaggaaagaggaagaaaaggcggtgctggcgaagg
gtcacagatggcaaatag

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Ontology (3)   
   KEGG BRITE (3)   
Pathway (3)   
   KEGG PATHWAY (3)   
Chemical substance (6)   
   KEGG COMPOUND (6)   
Chemical reaction (4)   
   KEGG ENZYME (1)   
   KEGG REACTION (3)   
Genome (1)   
   KEGG GENOME (1)   
Gene (35)   
   KEGG ORTHOLOGY (1)   
   KEGG GENES (1)   
   RefGene (26)   
   NCBI-PROTEINID (1)   
   NCBI-Gene (1)   
   Ensembl (1)   
   RIKEN BRC-DNA (3)   
   OC (1)   
Protein sequence (11)   
   UniProt (1)   
   SWISS-PROT (1)   
   RefSeq(pep) (9)   
DNA sequence (51)   
   RefSeq(nuc) (9)   
   GenBank (21)   
   EMBL (21)   
Protein domain (13)   
   Pfam (13)   
All databases (127)   

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