KEGG   Mus musculus (mouse): 109828
Entry
109828            CDS       T01002                                 

Gene name
C7, A530026G17, Gm1238
Definition
(RefSeq) complement component 7
  KO
K03996  complement component 7
Organism
mmu  Mus musculus (mouse)
Pathway
mmu04610  Complement and coagulation cascades
mmu05020  Prion disease
mmu05171  Coronavirus disease - COVID-19
mmu05322  Systemic lupus erythematosus
Brite
KEGG Orthology (KO) [BR:mmu00001]
 09150 Organismal Systems
  09151 Immune system
   04610 Complement and coagulation cascades
    109828 (C7)
 09160 Human Diseases
  09172 Infectious disease: viral
   05171 Coronavirus disease - COVID-19
    109828 (C7)
  09163 Immune disease
   05322 Systemic lupus erythematosus
    109828 (C7)
  09164 Neurodegenerative disease
   05020 Prion disease
    109828 (C7)
SSDB
Motif
Pfam: MACPF Kazal_3 Sushi Ldl_recept_a TSP_1
Other DBs
NCBI-GeneID: 109828
NCBI-ProteinID: NP_001230766
MGI: 88235
Ensembl: ENSMUSG00000079105
UniProt: D3YXF5
Position
15 A1; 15 1.98 cM
AA seq 845 aa
MQVTSLLILVCFIAAFQVFSRASSPVNCKWDSYGPWSECNGCTKTQTRRRSVAVYGQYGG
YPCEGSAFETQSCKPERGCPTEEGCGDRFRCFSGQCISKSLVCNGDPDCEEDGADEDKCE
NVANPSCNIDKPPPNIELTGYGYNVVTGQGKKRVINTKSFGGQCRKVFSGDGKDFYRLSG
NILSYTFQVKVDNDFNYEFYNSSWSYIKHTSTEQNTFYSWKGLFSHSRNTYGHGSAKEEI
DTKMKSYKLLVVQNTVEVAQFTNNNPEFLQVAEPFWKELSHLPTLYDYSAYRRLIDQYGT
HYLQSGSLGGEYRVLFYVDSGSAKETGFQSDQDNACSSADFQFLFTSSADQRCMKQLETE
KSTSGNKGRLLRGKPLVRGGDSGFVADLSFLDLDNPAGNKQRYSSWAGSVTRLPQVIKEK
LAPLYELVKEVPCASVKRLYLKRAIEEYFDEFDPCHCRPCQNGGLAIVVETQCQCLCKPY
TFGSACEQGVLVGDQAGGVDGGWNCWSSWSPCVQGKRTRSRECNNPPPRDDGKSCLGETT
ESKQCEDQDLEKLRLLEPHCFHSSLAPKEFCLSPPALKDGFVQGEGTMVPVGQSVVYACD
EGYSLIGDPVARCGEDLQWLVGEMHCQKLACVLPGEMNGMQSHPQKPFYMVGEKVTLSCV
GGMSLEGPSTLLCGSSLKWSPELKDAKCVQKATSTPPPAAPACQPWEKLQNSKCICKMPY
ECGSSLDVCARDESRNKILSLTICKMHVVHCHKRNYTLVGKESCTLPSPAEKVCGACPIW
SKCDAQNGKCICREASECQTAGYRICVEVNGKEETMSECEAGILRCRGQSISITAIKPCA
EEAAQ
NT seq 2538 nt   +upstreamnt  +downstreamnt
atgcaggtgacaagcttattaattttggtgtgctttatagcagcgtttcaagtcttctct
agagcctcctctccagtcaactgcaagtgggactcctatggcccttggtcagaatgcaat
ggctgtaccaagactcagactcgaaggcgttcagttgctgtttatgggcaatatggaggc
tatccatgtgaggggagtgcttttgaaacacaatcctgcaaacctgaacgaggctgtccg
acggaagagggctgtggggaccggtttaggtgtttttcaggtcagtgcatcagcaaatca
ttggtttgcaatggagatcctgactgtgaggaagacggtgctgatgaagacaaatgtgaa
aatgtggctaacccttcctgcaacattgataagcctcctcccaacatagaacttaccggt
tatggttacaacgtagttactggccagggtaagaaaagagtcatcaacaccaaaagtttc
ggtggtcagtgcaggaaagtgttcagcggggatggaaaagatttctacagactaagtgga
aatatcctctcttatacattccaggtcaaagtagataatgattttaactatgaattttac
aacagcagttggtcttacataaagcacacatccacagagcaaaacacattttattcatgg
aagggattattttcccactcacggaatacttacggtcatggttcagcaaaagaggaaatc
gacacgaaaatgaagagttataaattgttggttgttcagaacactgttgaagtggcccag
ttcactaataataatcctgaatttttacaagttgctgagccattctggaaggaactctcc
catcttcccactctgtatgactacagtgcctaccgacggttaatcgatcagtatgggaca
cattacctgcagtctgggtccttaggaggagaatatagagttctattttatgtggattca
ggaagtgccaaagaaactggttttcagtcagaccaggataacgcatgttcgtctgcagac
tttcagtttctttttacatcgtcagcagatcagagatgtatgaaacagctagagactgaa
aaatcaacttcaggaaataagggcaggttgcttcgaggaaaaccattggtcagaggtgga
gactctggctttgtagctgaccttagtttcctggacctggataatcctgctggaaacaag
cagcgctattcctcctgggctgggtctgtaaccagacttccccaagtcataaaagaaaag
ctggcgccgttgtatgagctggtcaaggaggtgccctgtgcctctgtgaaaagactgtac
ctgaagcgggctattgaggagtacttcgatgaatttgacccctgccattgccggccttgc
cagaatggcggcctcgctattgttgtggagacacagtgccagtgtctgtgcaaaccatac
acatttggttcagcgtgtgagcaaggagtccttgtcggcgatcaagcaggaggggttgat
ggaggttggaattgttggtcctcttggagcccctgtgttcaagggaagagaacaaggagc
cgggaatgcaataatccccctcccagagatgatggaaagtcctgtcttggagaaacaact
gagagtaagcagtgtgaagaccaggacttggagaaactgcgattacttgagccacattgc
tttcactcgtctttggctccaaaagaattctgcctatcaccccctgccttaaaagatgga
tttgttcaaggtgaaggtaccatggttcctgttggacaaagcgtagtatatgcttgtgat
gaggggtattctcttattggagatcctgttgccagatgtggagaagacttacagtggctt
gttggagaaatgcattgtcaaaaattggcctgcgttctacctggagagatgaatggcatg
cagagtcacccgcagaaacctttttacatggttggagagaaggtgactctttcctgtgtg
gggggtatgtccttagagggtccttcaaccctcctctgtggctccagcctgaagtggagt
cccgagctgaaggatgccaagtgtgtgcaaaaagctaccagcactccaccaccagcagcc
cctgcatgtcagccttgggagaaactgcagaactcaaaatgcatctgtaaaatgccctat
gaatgtggatcctccttggatgtatgtgcccgagatgagagtagaaacaagattctgtct
ctgaccatctgcaagatgcacgttgtccactgtcataaaagaaattacactcttgttggc
aaggaaagctgtactctgccttccccggctgagaaagtctgtggtgcatgcccaatatgg
agtaaatgtgatgctcagaatggcaaatgtatctgcagagaagcatcggagtgccagaca
gcaggctacagaatctgtgtggaagtgaatggcaaagaggaaacgatgtctgagtgtgag
gctggcatcttaagatgcagaggacagagcatctccatcacagccataaagccctgtgca
gaagaagcagcccagtag

KEGG   Mus musculus (mouse): 110382
Entry
110382            CDS       T01002                                 

Gene name
C8b, 4930439B20Rik, AI595927
Definition
(RefSeq) complement component 8, beta polypeptide
  KO
K03998  complement component 8 subunit beta
Organism
mmu  Mus musculus (mouse)
Pathway
mmu04610  Complement and coagulation cascades
mmu05020  Prion disease
mmu05146  Amoebiasis
mmu05171  Coronavirus disease - COVID-19
mmu05322  Systemic lupus erythematosus
Brite
KEGG Orthology (KO) [BR:mmu00001]
 09150 Organismal Systems
  09151 Immune system
   04610 Complement and coagulation cascades
    110382 (C8b)
 09160 Human Diseases
  09172 Infectious disease: viral
   05171 Coronavirus disease - COVID-19
    110382 (C8b)
  09174 Infectious disease: parasitic
   05146 Amoebiasis
    110382 (C8b)
  09163 Immune disease
   05322 Systemic lupus erythematosus
    110382 (C8b)
  09164 Neurodegenerative disease
   05020 Prion disease
    110382 (C8b)
SSDB
Motif
Pfam: MACPF Ldl_recept_a TSP_1 TSP1_spondin
Other DBs
NCBI-GeneID: 110382
NCBI-ProteinID: NP_598643
MGI: 88236
Ensembl: ENSMUSG00000029656
Vega: OTTMUSG00000008115
UniProt: Q8BH35
Position
4 C6; 4 48.61 cM
AA seq 589 aa
MKIGAQVWRALAKSCLLCATLGCLHFPGSRGGKPDFFETKAVNGSLVKSRPVRSVAEAPA
PIDCELSTWSSWTACDPCQKKRYRHTYLLRPSQFYGELCDLSDKEVEDCVTNQPCRSQVR
CEGFVCAQTGRCVNRRLLCNGDNDCGDQSDEANCRRIYKNCQREMEQYWAIDRLASGINL
FTNTFEGPVLDHRYYAGGCSPHYILDTNFRKPYNVESYTPQTKCEYEFTLTEYESYSDFE
RLVIEKKTHMFNFTSGFKVDGVMDLGIKVESNEGKNYVTRTKRFAHTQSKFLHARSVLEV
AHYKLKSRSLMLHYEFLQRVKSLPLEYSYGEYRDLLRDFGTHFITEAVLGGIYEYTLIMN
KDAMEQGDYTLSHVTACAGGSFGIGGMVYKVYVKVGVSAKKCSDIMKEINERNKRSTMVE
DLVVLVRGGTSEDITALAYKELPTPELMEAWGDAVKYNPAIIKIKAEPLYELVTATDFAY
SSTVKQNLKKALEEFQSEVSSCRCAPCRGNGVPVLKGSRCECICPGGFQGTACEVTYRKD
IPIDGKWSCWSDWSACSGGHKTRHRQCNNPAPHKGGSPCSGPASETLNC
NT seq 1770 nt   +upstreamnt  +downstreamnt
atgaagataggggctcaggtttggagggcactggcaaagtcgtgtctcctctgtgctact
ctgggatgtctccatttccctggttccagaggtgggaagcccgatttctttgagacaaag
gcagtcaatgggagccttgtcaagagcagaccagtacggagtgtggcggaagccccagca
cctattgactgtgagctatccacctggtcttcctggactgcatgtgacccctgtcagaag
aaaaggtacagacatacttacttgctccggccctctcagttctatggggaattgtgtgac
ttgtccgacaaggaagttgaagactgtgttaccaaccaaccctgcaggagtcaagtacga
tgtgaaggctttgtgtgtgcacagacagggaggtgtgtgaatcgcagactcctttgcaat
ggggacaatgactgtggagaccaatcagatgaagccaactgtaggaggatttataaaaac
tgtcaacgggagatggagcagtactgggcaattgacaggctggccagtgggataaatctg
ttcacaaacacttttgagggcccagttctcgatcaccggtattatgctggtggatgctcc
ccccactacatcctggacaccaactttaggaagccatacaacgtagaaagctacacccca
cagaccaaatgtgaatatgaattcacacttacagaatatgaatcatattcagattttgaa
cgtctagtgatagaaaagaaaacccacatgtttaatttcacgtctggttttaaagtggat
ggcgttatggatcttggaattaaagtagaaagcaacgaaggcaaaaattatgtgaccaga
accaaacgcttcgcccacactcaaagcaagttcctccacgcgcgctctgtccttgaagtg
gcacattacaagctgaagtctagaagcctcatgctccattatgaattccttcagagggtc
aagagcctgcccctggagtatagctatggggaataccgagatcttcttcgtgacttcggg
acccatttcatcactgaagccgtacttgggggcatctacgagtacacgcttatcatgaac
aaagacgccatggagcaaggagactacactcttagccatgttactgcctgtgctggagga
agtttcggtattggtggtatggtctataaagtctatgtcaaagtgggcgtttccgcaaag
aaatgcagtgacattatgaaagaaatcaacgaaagaaataagaggagcaccatggtagaa
gacttggtagttcttgtgagaggagggacaagtgaggatatcactgccttggcatacaag
gagctaccaacccctgaactgatggaggcatggggcgatgctgtgaagtacaacccagca
atcattaagatcaaggctgagcccctgtatgagcttgtgacagccacagactttgcatac
tccagcacagtgaagcagaacttaaagaaggcactagaagaattccagagtgaggtcagc
tcctgccgctgtgctccttgcagagggaatggagtccctgtcctgaaaggatcccgctgt
gagtgcatctgccccggtggcttccaaggcacagcctgtgaggttacctatcggaaagac
atccccatagatgggaagtggagttgctggtctgactggtctgcatgctctggaggacac
aaaacaagacacaggcagtgcaacaatccagcccctcacaaaggaggcagcccctgttcg
ggtcctgcttccgaaacactcaactgttaa

KEGG   Mus musculus (mouse): 12274
Entry
12274             CDS       T01002                                 

Gene name
C6, AW111623
Definition
(RefSeq) complement component 6
  KO
K03995  complement component 6
Organism
mmu  Mus musculus (mouse)
Pathway
mmu04610  Complement and coagulation cascades
mmu05020  Prion disease
mmu05171  Coronavirus disease - COVID-19
mmu05322  Systemic lupus erythematosus
Brite
KEGG Orthology (KO) [BR:mmu00001]
 09150 Organismal Systems
  09151 Immune system
   04610 Complement and coagulation cascades
    12274 (C6)
 09160 Human Diseases
  09172 Infectious disease: viral
   05171 Coronavirus disease - COVID-19
    12274 (C6)
  09163 Immune disease
   05322 Systemic lupus erythematosus
    12274 (C6)
  09164 Neurodegenerative disease
   05020 Prion disease
    12274 (C6)
SSDB
Motif
Pfam: MACPF Sushi TSP1_spondin Ldl_recept_a TSP_1 DUF5081
Other DBs
NCBI-GeneID: 12274
NCBI-ProteinID: NP_057913
MGI: 88233
Ensembl: ENSMUSG00000022181
Vega: OTTMUSG00000032527
UniProt: Q91X70
Position
15 A1; 15 1.97 cM
AA seq 769 aa
MTRHLTLCFILLVMLIDKSEACFCDHYPWTHWSSCSKSCNSGTQSRQRQVVVNDYYWKNL
CDKLCIKQETRECNLQTCPINCVLGDYGTWSDCDPCTEKQVKVKSVLRPSQFGGQPCTEP
LVTFQPCVPSKLCKIEETNCKNKFLCDSGRCIPSKLECNGENDCGDNSDERNCGRTKPVC
TRIYTPIPSVQLMGTGFHFLAGEPRGEVLDNSFTGGICKLVKTSRASNPYRVSANLENVN
FEVQTIEDDLKTEFYKNLISFEKNKNEDSLSVDERTKFFPIPIFHFSEKNEHSHYSSAFN
KVIKASHKKDSSFIRIHKLIKVLNFTMKATDLQLSDVFLKALVHLPLEYNSAVYSRIFDD
FGTHYFTSGSLGGKYDLIYQFSRQELQNSGLTEEEAQNCVQYETKKLKFLYMEIHKEDTC
TKNKLSEKYGGSFLQGSEKSISLVQGGRSQQAAALAWEKGTSGPEENVYSEWLESVKENP
AVVDYKLAPITDLVRNIPCAVTKRNNLRRALQEYAAKFDPCQCAPCPNNGRPRLSGTECL
CVCQSGTYGENCERRSPGYKSDAVDGNWGCWSSWSACNAAYRRSRTRECNNPAPQRGGQS
CGGKDQQEEDCTVSIMENVGQPCINDDEEMKEVDLAEPEAESGCSQPPLPENAFTWNEKK
LYSVGEEVEISCLTGFTAVGFQYLRCLPDRTWSQGDVECQRTSCLKPVVQDVLTISPFQR
VYQIGESIELTCPRGFVVAGPSRYTCKEDSWTPPISNSLTCEQGVRDHP
NT seq 2310 nt   +upstreamnt  +downstreamnt
atgaccagacatctcaccttgtgtttcattttgctggtcatgctgattgacaagagtgaa
gcctgtttctgtgaccactacccatggactcactggtccagctgttctaagtcctgcaat
tctggaacccagagcagacagagacaagtagtagtgaacgattactattggaaaaactta
tgcgataagctttgtatcaagcaggagaccagagagtgcaacttgcagacatgtcccatc
aactgtgtcctaggagactatgggacatggtcagactgtgacccttgtactgaaaaacag
gttaaagttaaatctgtcctgcgcccaagtcagtttggggggcaaccatgcacagagccc
ctggtgacctttcaaccatgtgtcccctccaagctctgcaaaattgaagagactaactgc
aagaataagttcctctgtgacagtgggcgctgtattcccagcaagttagaatgcaatgga
gagaatgactgtggagacaattcagatgaaaggaactgtgggaggacaaagccagtgtgc
acacggatatacactcccatccctagtgtgcagctgatgggcactgggtttcattttctg
gcaggagagcccagaggagaagttcttgacaactctttcactggaggaatatgtaaactt
gtcaagaccagtcgagccagtaatccataccgtgtttcagccaatctggaaaatgtcaac
tttgaggtacaaactatagaagatgacttgaaaacagaattctacaagaatttaatctct
tttgaaaaaaataaaaatgaagacagtctttcagtggatgaaaggacaaaatttttccct
ataccaattttccatttctcagagaaaaatgaacattcccattatagctctgccttcaac
aaagtcattaaagcttcccacaagaaggattctagctttatcaggatccataagctgata
aaagtcttaaacttcacaatgaaagcaacagacctacagctttcagatgtcttcctgaaa
gcccttgtccacctgcctttagaatacaactctgctgtgtacagccggatatttgatgac
ttcgggacccactacttcacctcaggctcccttgggggcaagtatgaccttatctaccaa
ttcagccgccaggagctacagaactcaggtttaacagaagaagaagctcaaaactgtgtc
cagtatgaaacaaagaaacttaagtttctttatatggaaatacacaaggaagacacgtgc
accaaaaacaagctgtctgaaaaatatggaggttcctttttgcagggatcagagaaatcc
atttccctggtccagggcgggaggagtcagcaggcagcagccttggcttgggagaagggc
acctctggtccagaggagaatgtctattctgagtggctagaatcggtgaaggaaaaccct
gctgtagttgattataagcttgccccaattacagacttggtcagaaacatcccatgtgca
gtgacaaaacggaacaacctcaggagagcgcttcaagagtatgcagccaagtttgaccct
tgccagtgtgctccatgtcccaataatggccgccccaggctctcaggcacggaatgcctg
tgtgtgtgccagagcggcacctacggtgagaactgtgagcgcaggtccccaggttacaaa
tctgatgcagtggatggaaactggggctgctggtcttcctggagtgcgtgcaatgctgct
tataggagatcaagaacccgagagtgtaataaccctgcgccacagcgaggaggacaaagc
tgtggtggcaaggatcagcaagaagaagactgtacagtctcaataatggaaaatgttgga
caaccatgtatcaatgatgatgaagaaatgaaagaagtagaccttgctgagccagaagca
gaatcagggtgttctcaaccacctctcccagaaaacgcatttacctggaatgagaagaaa
ctgtactcagttggggaggaagttgaaatttcatgtcttactggattcacagctgttgga
ttccagtacttgagatgtttaccagacagaacctggagtcaaggagatgtggaatgccaa
aggacctcgtgcctcaagcccgttgttcaggatgtcctgaccatctccccatttcagaga
gtgtatcagattggggaatccattgagctgacatgccccagaggctttgttgttgctgga
ccatcaaggtatacatgcaaggaagactcctggacacctcccatttcaaattcattgacc
tgtgaacaaggtgtcagagaccatccgtga

KEGG   Mus musculus (mouse): 12279
Entry
12279             CDS       T01002                                 

Gene name
C9
Definition
(RefSeq) complement component 9
  KO
K04000  complement component 9
Organism
mmu  Mus musculus (mouse)
Pathway
mmu04610  Complement and coagulation cascades
mmu05020  Prion disease
mmu05146  Amoebiasis
mmu05171  Coronavirus disease - COVID-19
mmu05322  Systemic lupus erythematosus
Brite
KEGG Orthology (KO) [BR:mmu00001]
 09150 Organismal Systems
  09151 Immune system
   04610 Complement and coagulation cascades
    12279 (C9)
 09160 Human Diseases
  09172 Infectious disease: viral
   05171 Coronavirus disease - COVID-19
    12279 (C9)
  09174 Infectious disease: parasitic
   05146 Amoebiasis
    12279 (C9)
  09163 Immune disease
   05322 Systemic lupus erythematosus
    12279 (C9)
  09164 Neurodegenerative disease
   05020 Prion disease
    12279 (C9)
SSDB
Motif
Pfam: MACPF Ldl_recept_a TSP1_spondin TSP_1
Other DBs
NCBI-GeneID: 12279
NCBI-ProteinID: NP_038513
MGI: 1098282
Ensembl: ENSMUSG00000022149
Vega: OTTMUSG00000026361
UniProt: P06683 A0A0R4J032
Structure
PDB: 
6CXO

Position
15; 15 A1
AA seq 548 aa
MASGMAITLALAIFALGVNAQMPIPVSREEQEQHYPIPIDCRMSPWSNWSECDPCLKQRF
RSRSILAFGQFNGKSCVDVLGDRQGCEPTQECEEIQENCGNDFQCETGRCIKRRLLCNGD
NDCGDYSDENDCDDDPRTPCRDRVAEESELGLTAGYGINILGMEPLRTPFDNEFYNGLCD
RVRDEKTYYRKPWNVVSLIYETKADKSFRTENYDEHLEVFKAINREKTSNFNADFALKFS
ATEVPEKGAGEVSPAEHSSKPTNISAKFKFSYFMGKNFRRLSSYFSQSKKMFVHLRGVVQ
LGRFVMRNRDVVLRSTFLDDVKALPTSYEKGEYFGFLETYGTHYSTSGSLGGQYEIVYVL
DKASMKEKGVDLNDVKHCLGFNMDLRIPLQDDLKDASVTASVNADGCIKTDNGKTVNITR
DNIIDDVISFIRGGTREQAILLKEKILRGDKTFDKTDFANWASSLANAPALISQRMSPIY
NLIPLKIKDAYIKKQNLEKAVEDYIDEFSTKRCYPCLNGGTIILLDGQCLCSCPMMFRGM
ACEIHQKI
NT seq 1647 nt   +upstreamnt  +downstreamnt
atggcctcaggcatggccatcaccttagcccttgccatctttgccttgggtgtcaatgca
cagatgccaatacccgtttccagagaagaacaagaacaacactatcccataccgatagac
tgcagaatgagcccatggagcaattggtcagagtgtgatccttgcctcaaacaaaggttt
cgctcaagaagcattttagccttcggacagtttaatgggaaaagctgtgttgatgttttg
ggagacagacaaggctgtgaacccacccaggagtgtgaagagatacaggaaaactgtgga
aatgactttcagtgtgagacaggcaggtgcataaagaggagacttctgtgtaatggtgac
aacgactgtggagattattctgatgagaatgactgtgacgatgacccacgcaccccatgc
cgtgaccgagtagcggaagaatcagagctgggactaacagcaggctatgggatcaacatc
ttagggatggagcccctgagaacaccttttgacaatgagttctacaacggactctgtgac
cgggtacgagacgaaaagacatactatcgcaaaccttggaatgtagtttctctgatctat
gaaaccaaggctgataaaagtttcagaactgagaactatgacgaacacttggaagtattc
aaagccatcaaccgagagaagacctcgaattttaatgcagattttgccctaaaattttca
gccaccgaagtacctgaaaagggagctggggaagtctccccagcagaacactcttcaaaa
cctacaaacatttcagctaaatttaaattttcatatttcatgggaaaaaattttcgaaga
ctatcatcttatttttcgcagtcgaaaaagatgtttgtgcacttgagaggagtggtccaa
ctggggagatttgtaatgaggaatcgggatgttgtgctgaggtcaactttcctggatgat
gtaaaagctctaccaacttcctatgaaaagggagaatattttggatttttggaaacctat
gggactcactacagtacctctgggtccctgggaggacaatatgaaattgtctatgtcttg
gataaagcttccatgaaagagaaaggtgttgacctgaatgatgtaaaacattgtcttgga
tttaatatggatttacgtattcctctacaagacgacttaaaggatgcatcagtcacagca
agtgttaatgcggatggttgcataaagacagataatgggaaaactgtaaacatcacccgc
gataacatcatagatgatgtcatttcattcataagaggagggactagggagcaagcaatt
ctcctgaaagagaagattctcagaggagacaagacatttgataagactgacttcgccaac
tgggcctcgtccctggcaaacgctccagctctcatcagtcaaagaatgtcccctatatat
aatctcattcctttgaaaataaaagatgcatacataaagaagcaaaatttggaaaaggct
gttgaagactatatagatgaattcagtactaaaaggtgctacccatgtctaaatggaggt
actataattcttctggatgggcagtgcctgtgctcctgcccaatgatgtttaggggaatg
gcctgcgaaatccatcaaaaaatatag

KEGG   Mus musculus (mouse): 15139
Entry
15139             CDS       T01002                                 

Gene name
Hc, C5, C5a, He, Hfib, Hfib2
Definition
(RefSeq) hemolytic complement
  KO
K03994  complement component 5
Organism
mmu  Mus musculus (mouse)
Pathway
mmu04080  Neuroactive ligand-receptor interaction
mmu04610  Complement and coagulation cascades
mmu04613  Neutrophil extracellular trap formation
mmu05020  Prion disease
mmu05133  Pertussis
mmu05150  Staphylococcus aureus infection
mmu05168  Herpes simplex virus 1 infection
mmu05171  Coronavirus disease - COVID-19
mmu05322  Systemic lupus erythematosus
Brite
KEGG Orthology (KO) [BR:mmu00001]
 09130 Environmental Information Processing
  09133 Signaling molecules and interaction
   04080 Neuroactive ligand-receptor interaction
    15139 (Hc)
 09150 Organismal Systems
  09151 Immune system
   04610 Complement and coagulation cascades
    15139 (Hc)
   04613 Neutrophil extracellular trap formation
    15139 (Hc)
 09160 Human Diseases
  09172 Infectious disease: viral
   05171 Coronavirus disease - COVID-19
    15139 (Hc)
   05168 Herpes simplex virus 1 infection
    15139 (Hc)
  09171 Infectious disease: bacterial
   05133 Pertussis
    15139 (Hc)
   05150 Staphylococcus aureus infection
    15139 (Hc)
  09163 Immune disease
   05322 Systemic lupus erythematosus
    15139 (Hc)
  09164 Neurodegenerative disease
   05020 Prion disease
    15139 (Hc)
 09180 Brite Hierarchies
  09181 Protein families: metabolism
   01002 Peptidases and inhibitors [BR:mmu01002]
    15139 (Hc)
Peptidases and inhibitors [BR:mmu01002]
 Peptidase inhibitors
  Family I39: alpha2M family
   15139 (Hc)
SSDB
Motif
Pfam: TED_complement MG1 MG4 A2M A2M_BRD NTR A2M_recep MG2 MG3 ANATO VIT
Other DBs
NCBI-GeneID: 15139
NCBI-ProteinID: NP_034536
MGI: 96031
Ensembl: ENSMUSG00000026874
Vega: OTTMUSG00000012274
UniProt: P06684
Structure
PDB: 
4P3A 4WB2 4WB3 4P3B

Position
2 B; 2 23.22 cM
AA seq 1680 aa
MGLWGILCLLIFLDKTWGQEQTYVISAPKILRVGSSENVVIQVHGYTEAFDATLSLKSYP
DKKVTFSSGYVNLSPENKFQNAALLTLQPNQVPREESPVSHVYLEVVSKHFSKSKKIPIT
YNNGILFIHTDKPVYTPDQSVKIRVYSLGDDLKPAKRETVLTFIDPEGSEVDIVEENDYT
GIISFPDFKIPSNPKYGVWTIKANYKKDFTTTGTAYFEIKEYVLPRFSVSIELERTFIGY
KNFKNFEITVKARYFYNKVVPDAEVYAFFGLREDIKDEEKQMMHKATQAAKLVDGVAQIS
FDSETAVKELSYNSLEDLNNKYLYIAVTVTESSGGFSEEAEIPGVKYVLSPYTLNLVATP
LFVKPGIPFSIKAQVKDSLEQAVGGVPVTLMAQTVDVNQETSDLETKRSITHDTDGVAVF
VLNLPSNVTVLKFEIRTDDPELPEENQASKEYEAVAYSSLSQSYIYIAWTENYKPMLVGE
YLNIMVTPKSPYIDKITHYNYLILSKGKIVQYGTREKLFSSTYQNINIPVTQNMVPSARL
LVYYIVTGEQTAELVADAVWINIEEKCGNQLQVHLSPDEYVYSPGQTVSLDMVTEADSWV
ALSAVDRAVYKVQGNAKRAMQRVFQALDEKSDLGCGAGGGHDNADVFHLAGLTFLTNANA
DDSHYRDDSCKEILRSKRNLHLLRQKIEEQAAKYKHSVPKKCCYDGARVNFYETCEERVA
RVTIGPLCIRAFNECCTIANKIRKESPHKPVQLGRIHIKTLLPVMKADIRSYFPESWLWE
IHRVPKRKQLQVTLPDSLTTWEIQGIGISDNGICVADTLKAKVFKEVFLEMNIPYSVVRG
EQIQLKGTVYNYMTSGTKFCVKMSAVEGICTSGSSAASLHTSRPSRCVFQRIEGSSSHLV
TFTLLPLEIGLHSINFSLETSFGKDILVKTLRVVPEGVKRESYAGVILDPKGIRGIVNRR
KEFPYRIPLDLVPKTKVERILSVKGLLVGEFLSTVLSKEGINILTHLPKGSAEAELMSIA
PVFYVFHYLEAGNHWNIFYPDTLSKRQSLEKKIKQGVVSVMSYRNADYSYSMWKGASAST
WLTAFALRVLGQVAKYVKQDENSICNSLLWLVEKCQLENGSFKENSQYLPIKLQGTLPAE
AQEKTLYLTAFSVIGIRKAVDICPTMKIHTALDKADSFLLENTLPSKSTFTLAIVAYALS
LGDRTHPRFRLIVSALRKEAFVKGDPPIYRYWRDTLKRPDSSVPSSGTAGMVETTAYALL
ASLKLKDMNYANPIIKWLSEEQRYGGGFYSTQDTINAIEGLTEYSLLLKQIHLDMDINVA
YKHEGDFHKYKVTEKHFLGRPVEVSLNDDLVVSTGYSSGLATVYVKTVVHKISVSEEFCS
FYLKIDTQDIEASSHFRLSDSGFKRIIACASYKPSKEESTSGSSHAVMDISLPTGIGANE
EDLRALVEGVDQLLTDYQIKDGHVILQLNSIPSRDFLCVRFRIFELFQVGFLNPATFTVY
EYHRPDKQCTMIYSISDTRLQKVCEGAACTCVEADCAQLQAEVDLAISADSRKEKACKPE
TAYAYKVRITSATEENVFVKYTATLLVTYKTGEAADENSEVTFIKKMSCTNANLVKGKQY
LIMGKEVLQIKHNFSFKYIYPLDSSTWIEYWPTDTTCPSCQAFVENLNNFAEDLFLNSCE
NT seq 5043 nt   +upstreamnt  +downstreamnt
atgggtctttggggaatactttgtcttttaattttcctggacaaaacttggggacaggaa
caaacctacgtcatttcagcacccaaaatcctccgggtcggctcgtctgaaaatgtggta
attcaagtccatggctacactgaagcatttgatgcaactctttctctaaaaagctatcct
gacaaaaaagtcaccttctcttcaggctatgttaatttgtccccggaaaacaaattccaa
aacgcggcactgttgacactacagcccaatcaagttcctagagaagaaagcccagtctct
cacgtgtatctggaagttgtgtcaaaacacttttcaaaatcaaagaaaataccaattacc
tataacaatggaattctcttcatccatacagacaaacctgtttacacgccggaccagtca
gtaaagatcagagtctattctctgggtgacgacttgaagccagccaaacgggagactgtc
ttaactttcatagaccccgaaggatcagaagttgacattgtagaagaaaatgattacacc
ggaattatctcttttcctgacttcaagattccatctaatcccaagtatggtgtttggaca
attaaagctaactataagaaggattttacaacaactggaactgcatactttgaaattaaa
gaatatgtcttgccacgattctctgtttcaatagaactagaaagaaccttcattggctat
aaaaactttaagaactttgaaatcactgtgaaagcaagatatttttataataaagtggta
cctgatgctgaagtgtatgccttttttggattgagagaggacataaaagatgaggagaag
cagatgatgcacaaagccacacaagccgcaaagttggttgacggagttgctcagatctct
tttgattctgaaacagcagttaaagagctgtcctacaacagtctagaagacttaaacaac
aagtacctttatattgcagtaacagtcacagaatcttcaggtggattttcagaagaggca
gaaatccctggagtcaaatatgtcctctctccctacacactgaatttggtcgctactcct
cttttcgtgaagcccgggattccattttccatcaaggcacaggttaaagattcactcgag
caggcggtaggaggggtcccagtaactctgatggcacaaacagtcgatgtgaatcaagag
acatctgacttggaaacaaagaggagcatcactcatgacactgatggagtagctgtgttt
gtgctgaacctcccatcaaatgtgacggtgctaaagtttgagatcagaactgatgaccca
gaacttcccgaagaaaatcaagccagcaaagagtacgaagcagttgcgtactcgtctctc
agccaaagttacatttacatcgcttggactgaaaactacaagcccatgcttgtgggagaa
tacctgaatattatggttacccccaagagcccatatatcgacaaaataactcactataat
tacttgattttatccaaaggcaaaattgtacagtacggcacaagagagaaacttttctcc
tcaacttatcaaaatataaatattccagtgacacagaacatggttccttcagcacgactc
ctggtctattacatagtcacaggggagcaaacagcagaattagtggctgacgcagtctgg
ataaatattgaggagaagtgtggcaaccagctccaggtccatctgtctccagatgaatat
gtgtattctccaggccaaactgtgtcccttgacatggtgactgaagcagactcatgggta
gcactatcagcagtggacagagctgtgtataaagtccagggaaacgccaaaagggccatg
caaagagtctttcaagctttggatgaaaagagtgacctgggctgtggggcaggtggtggc
catgacaatgcagatgtattccatctagctgggctcaccttcctcaccaacgcaaacgca
gatgactcccattatcgtgatgactcttgtaaagaaattctcaggtcaaagagaaacctg
catctcctaaggcagaaaatagaagaacaagctgctaagtacaaacatagtgtgccaaag
aaatgctgctatgacggagcccgagtgaacttctacgaaacctgtgaggagcgagtggcc
cgggttaccataggccctctctgcatcagggccttcaacgagtgctgtactattgcgaac
aagatccgaaaagaaagcccccataaacctgtccaactgggaaggatccacattaagacc
ctgttaccagtgatgaaggcagatatccgaagctactttccagagagctggctatgggaa
attcatcgcgttcccaaaagaaaacagctgcaggtcacgctgcctgactcactaacgact
tgggaaattcaaggcattggcatttcagacaatggtatatgtgttgctgatacactcaag
gcaaaggtgttcaaagaagtcttcctggagatgaacataccatattctgttgtgcgagga
gaacagatccaattgaaaggaactgtttacaactatatgacctcagggacaaagttctgt
gttaaaatgtctgctgtggaggggatctgcacttcaggaagctcagctgctagccttcac
acctccaggccctccagatgtgtgttccagaggatagagggctcgtccagtcacttggtg
accttcaccctgcttcctctggaaattggccttcactccataaacttctcactagagacc
tcatttgggaaagacatcttagtaaagacattacgggtagtgccagaaggagtcaagagg
gaaagctatgccggcgtgattctggaccctaagggaattcgtggtattgttaacagacga
aaggaattcccatacaggatcccattagatttggtccccaagaccaaagttgaaaggatt
ttgagtgtcaaaggactgcttgtaggggagttcttgtccacggttctgagtaaggaaggc
atcaacatcctaacccacctccccaagggcagtgcagaggcagagctcatgagcatagct
ccggtgttctatgttttccactacctggaagcaggaaaccattggaatattttctatcct
gatacactgagtaaaagacagagcctggagaaaaaaataaaacaaggggtggtgagcgtc
atgtcctacagaaacgctgactattcctacagcatgtggaagggggcgagcgctagtacc
tggctgacagcttttgctctgagagtgcttggacaggtggccaagtatgtaaaacaggat
gaaaactcaatttgtaactctttgctatggctggttgagaagtgtcagctggaaaacggc
tctttcaaggaaaattcccaatatctaccaataaaattacagggtactttgcctgctgaa
gcccaagagaaaactttgtatcttacagccttttctgtgattggaattagaaaggcagtt
gacatatgccccaccatgaaaatccacacagcgctagataaagccgactccttcctgctt
gaaaacaccctgccatccaagagcaccttcacactggccattgtagcctatgctctttcc
ctaggagacagaacccacccgaggtttcgtctaattgtgtcggccctgaggaaggaagct
tttgttaaaggtgatccgcccatttaccgttactggagagataccctcaaacgtccagac
agctctgtgcccagcagcggcacagcaggtatggttgaaaccacagcctatgctttgctc
gccagcctgaaactgaaggatatgaattacgccaaccccatcatcaagtggctatctgaa
gagcagaggtatggaggcggcttttattccacccaggatacgattaatgccatcgagggc
ctgacagaatattcactcctgttaaaacaaattcatttggatatggacatcaatgtcgcc
tacaaacacgaaggtgacttccacaagtataaggtgacagagaagcatttcctggggagg
ccagtggaggtatctctcaatgatgaccttgttgtcagcacaggctacagcagtggcttg
gccacagtatatgtaaaaactgtggttcacaaaattagtgtctctgaggaattttgcagc
ttttacttgaaaattgatacccaagatattgaagcatccagccacttcaggctcagtgac
tctggattcaagcgcataatagcatgtgccagctacaagcccagcaaggaggagtcaaca
tccgggtcctcccatgcagtaatggatatatcactgccgactggaatcggagcaaacgag
gaagatttacgggctcttgtggaaggagtggatcaactactaactgattaccagatcaaa
gatggccatgtcattctgcaactgaattcgatcccctccagagatttcctctgtgtccgg
ttccggatatttgaacttttccaagttgggtttctgaatcctgctaccttcacggtgtac
gagtatcacagaccagataagcagtgcaccatgatttatagcatttctgacaccaggctt
cagaaagtctgtgaaggagcagcttgcacatgtgtggaagctgactgtgcgcaactgcag
gcagaagtagacctagccatctctgcagactccagaaaagagaaagcctgtaaaccagag
actgcatatgcttataaagtcaggatcacatcagccactgaagaaaatgtttttgtcaag
tacactgcgactcttctggtcacttacaaaacaggggaagctgctgatgagaattcggag
gtcaccttcattaaaaagatgagctgtaccaatgccaacctggtgaaagggaagcagtat
ttaatcatgggcaaagaggttctgcagatcaaacacaatttcagtttcaagtatatatac
cctctagattcctccacctggattgaatattggcccacagacacaacgtgtccatcctgt
caagcatttgtagagaatttgaataactttgctgaagacctctttttaaacagctgtgaa
tga

KEGG   Mus musculus (mouse): 230558
Entry
230558            CDS       T01002                                 

Gene name
C8a
Definition
(RefSeq) complement component 8, alpha polypeptide
  KO
K03997  complement component 8 subunit alpha
Organism
mmu  Mus musculus (mouse)
Pathway
mmu04610  Complement and coagulation cascades
mmu05020  Prion disease
mmu05146  Amoebiasis
mmu05171  Coronavirus disease - COVID-19
mmu05322  Systemic lupus erythematosus
Brite
KEGG Orthology (KO) [BR:mmu00001]
 09150 Organismal Systems
  09151 Immune system
   04610 Complement and coagulation cascades
    230558 (C8a)
 09160 Human Diseases
  09172 Infectious disease: viral
   05171 Coronavirus disease - COVID-19
    230558 (C8a)
  09174 Infectious disease: parasitic
   05146 Amoebiasis
    230558 (C8a)
  09163 Immune disease
   05322 Systemic lupus erythematosus
    230558 (C8a)
  09164 Neurodegenerative disease
   05020 Prion disease
    230558 (C8a)
SSDB
Motif
Pfam: MACPF Ldl_recept_a TSP_1 TSP1_spondin
Other DBs
NCBI-GeneID: 230558
NCBI-ProteinID: NP_666260
MGI: 2668347
Ensembl: ENSMUSG00000035031
Vega: OTTMUSG00000008116
UniProt: Q8K182
Position
4; 4 C6
AA seq 587 aa
MFVVAFFGLSLVAWHPGVTAQEKVNQRVTRAVTPQAVSCQLSDWYKWTDCFPCQDKKYRY
RSLLQPSKFGGTICSGDIWDEASCDSPTPCLRQAQCGQDFQCRETGRCLKRHLVCNGDND
CLDGSDESDCEDVRVTEDDCHQYEPIPGSERAALGYNILTQEEAQSVYDAKYYGGQCETV
YNGDWRKLRYDPTCERLYYGEDEKYFRKPYNFLKYHFEALADTSISSEFYDDANDLFFHI
KNGKSHSAGVTVGVAPVKSPVSIEVTGSGSKASSFLNKLNKYNEKRYGFMRVSTKIQTAQ
FKMRRNNIVLDEGMLQSLMELPEQFNYGMYAKFINDYGTHYITSGTMGGIYEYVMVLDKE
KMKTEGTTVDEVQKCIGGGIGIGIKDSTIEGVGISGEFCENSGDGDRDIRKKITGVEDII
SRVQGGSSVWGSVLTHNSSAITYQSWGRSLKYNPVVIDFEMQPIYQLLRHTNLGPLETKR
QNLRRALDQYLMEFNACRCGPCFNNGEPILDGTNCRCQCSMGRQGLACERTVIEGLKDFK
AAGHWSCWSSWSECRGGSQERRRQCNNPPPKNGGTPCLGRNLQTQAC
NT seq 1764 nt   +upstreamnt  +downstreamnt
atgtttgtggttgctttctttggcttgtctttggtggcatggcaccctggggtaactgca
caagagaaggtgaaccagcgggtcacccgagctgtgaccccgcaagcagtgtcctgtcag
ttgagtgactggtacaaatggacagattgttttccatgtcaggataaaaagtaccgatac
cggagcctcttgcagccaagcaagtttggaggaaccatctgcagtggtgatatctgggat
gaggccagctgtgacagccccacaccttgtctaaggcaagcacagtgtggacaggatttc
cagtgtagagagacaggtcgctgcctgaaacgccacctggtgtgtaacggagataacgac
tgcctggatggctctgatgagtccgactgtgaagatgtcagggtcactgaggatgattgc
catcagtatgaaccaatcccaggatcagaaagggcagccttggggtacaacatcctgact
caagaggaagctcagagtgtttacgatgctaagtattatgggggccagtgtgaaactgtg
tacaatggagactggagaaagctgcggtacgaccccacctgtgagcgcctctactatggg
gaggatgagaaatactttcggaagccctacaacttccttaagtaccactttgaagccctg
gcggatacttcaatctcctcagagttttatgatgatgcgaatgatcttttttttcacata
aagaatggcaagtcccactcagctggtgtaaccgttggcgtagccccagtaaaaagtcct
gtctcaatagaggtgactggatccgggtccaaagcatcttcattcctgaacaagttaaac
aagtataatgagaagagatatggcttcatgagagtgtctacaaagatacagactgcacag
tttaagatgagaaggaacaatattgtgctggatgaaggaatgctgcagtcattaatggag
ctcccagagcagttcaactatggcatgtacgccaagttcatcaatgactatggcacccac
tacatcacctctggaaccatgggtggcatttatgaatatgttatggtgcttgacaaagag
aaaatgaaaactgaaggtactactgtggatgaagtccaaaaatgcattggcggtggcatt
ggcataggaattaaggatagtacaattgaaggagtaggtatatcaggagagttttgtgaa
aactctggagatggtgaccgtgacataaggaagaaaatcacaggagtggaggacatcatt
tctcgggtgcaaggtggaagttctgtctggggcagtgtcttgacacacaacagcagtgcc
attacatatcagtcctgggggagatcgttaaagtataaccctgttgttatcgattttgag
atgcagcctatctaccagctactgcggcacacaaacttgggacccctggagacgaaacgt
cagaacctgcgacgggctttggaccagtacctgatggaatttaatgcctgtcgttgtggg
ccctgcttcaacaatggggaacccatacttgacggcaccaactgccggtgtcagtgtagt
atgggccggcagggcctggcctgtgaacgcacggtgatagaggggctcaaagacttcaaa
gccgctggccactggagctgctggagttcctggtcagagtgcagaggaggttcccaggag
aggaggagacagtgcaacaacccaccacccaagaatggaggtaccccatgcctagggagg
aacctgcagacccaggcctgctga

KEGG   Mus musculus (mouse): 69379
Entry
69379             CDS       T01002                                 

Gene name
C8g
Definition
(RefSeq) complement component 8, gamma polypeptide
  KO
K03999  complement component 8 subunit gamma
Organism
mmu  Mus musculus (mouse)
Pathway
mmu04610  Complement and coagulation cascades
mmu05020  Prion disease
mmu05146  Amoebiasis
mmu05171  Coronavirus disease - COVID-19
mmu05322  Systemic lupus erythematosus
Brite
KEGG Orthology (KO) [BR:mmu00001]
 09150 Organismal Systems
  09151 Immune system
   04610 Complement and coagulation cascades
    69379 (C8g)
 09160 Human Diseases
  09172 Infectious disease: viral
   05171 Coronavirus disease - COVID-19
    69379 (C8g)
  09174 Infectious disease: parasitic
   05146 Amoebiasis
    69379 (C8g)
  09163 Immune disease
   05322 Systemic lupus erythematosus
    69379 (C8g)
  09164 Neurodegenerative disease
   05020 Prion disease
    69379 (C8g)
SSDB
Motif
Pfam: Lipocalin
Other DBs
NCBI-GeneID: 69379
NCBI-ProteinID: NP_081338
MGI: 88237
Ensembl: ENSMUSG00000015083
Vega: OTTMUSG00000012120
UniProt: Q8VCG4 Q9DAC2
Position
2 A3; 2 17.31 cM
AA seq 202 aa
MLSPGAVLFFTLLLTASSLGQRTRKPIGSTSPISTIQAQVNFSAQKFAGTWLLVAVGSSC
RFLQEQGHRAEATTLHAAPQGAAMAVSTFRKLDGICWQVRQLFENTGVPGRFLFQVSRAR
GPVHMVVAETDYQSFAILYLEQGRKLSVKLYVRSLPVNDSVLDVFERRVREANLTEDQIL
FFPKYGFCETADQLHILNEVPR
NT seq 609 nt   +upstreamnt  +downstreamnt
atgctgtctccaggggctgtgttgttcttcaccctgctcttgacagccagttcgctgggc
caaaggactcgaaagcctattgggtctacctcccccatcagcactatccaggcccaggtc
aatttcagtgctcagaagtttgcagggacatggctcctggtggctgtgggctcttcgtgc
cgctttcttcaggagcagggacaccgagctgaggccaccacattgcacgcagctccccag
ggtgcagctatggctgtcagcaccttccgaaagctagatgggatatgttggcaggtacgc
caactctttgagaacacaggggtccctggccgcttcttgttccaagtctcacgggcccgt
ggaccagtgcatatggtggttgctgagactgactatcagagctttgccatcctgtacctg
gaacagggaaggaagctgtctgtgaaactatacgtccgctcactgccagtgaatgactct
gtcctggatgtgtttgagcggcgagtcagggaagccaacctgacagaagatcagattctt
ttctttcccaagtatggtttctgcgagactgcggaccaattacacatcctgaacgaggtg
ccgcgataa

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