KEGG   Mus musculus (house mouse): 110355
Entry
110355            CDS       T01002                                 
Symbol
Grk2, Adrbk-1, Adrbk1, Bark-1, beta_ARK, betaARK1
Name
(RefSeq) G protein-coupled receptor kinase 2
  KO
K00910  beta-adrenergic-receptor kinase [EC:2.7.11.15]
Organism
mmu  Mus musculus (house mouse)
Pathway
mmu04062  Chemokine signaling pathway
mmu04144  Endocytosis
mmu04340  Hedgehog signaling pathway
mmu04724  Glutamatergic synapse
mmu04740  Olfactory transduction
mmu05032  Morphine addiction
Brite
KEGG Orthology (KO) [BR:mmu00001]
 09130 Environmental Information Processing
  09132 Signal transduction
   04340 Hedgehog signaling pathway
    110355 (Grk2)
 09140 Cellular Processes
  09141 Transport and catabolism
   04144 Endocytosis
    110355 (Grk2)
 09150 Organismal Systems
  09151 Immune system
   04062 Chemokine signaling pathway
    110355 (Grk2)
  09156 Nervous system
   04724 Glutamatergic synapse
    110355 (Grk2)
  09157 Sensory system
   04740 Olfactory transduction
    110355 (Grk2)
 09160 Human Diseases
  09165 Substance dependence
   05032 Morphine addiction
    110355 (Grk2)
 09180 Brite Hierarchies
  09181 Protein families: metabolism
   01001 Protein kinases [BR:mmu01001]
    110355 (Grk2)
  09183 Protein families: signaling and cellular processes
   04147 Exosome [BR:mmu04147]
    110355 (Grk2)
Enzymes [BR:mmu01000]
 2. Transferases
  2.7  Transferring phosphorus-containing groups
   2.7.11  Protein-serine/threonine kinases
    2.7.11.15  beta-adrenergic-receptor kinase
     110355 (Grk2)
Protein kinases [BR:mmu01001]
 Serine/threonine kinases: AGC group
  GRK family [OT]
   110355 (Grk2)
Exosome [BR:mmu04147]
 Exosomal proteins
  Exosomal proteins of haemopoietic cells  (B-cell, T-cell, DC-cell, reticulocyte, and mast cell)
   110355 (Grk2)
SSDB
Motif
Pfam: Pkinase PK_Tyr_Ser-Thr RGS PH Kinase-like DUF5647 Haspin_kinase
Other DBs
NCBI-GeneID: 110355
NCBI-ProteinID: NP_001277747
MGI: 87940
Ensembl: ENSMUSG00000024858
UniProt: Q99MK8 Q3U1V3
Position
19:complement(4336029..4356356)
AA seq 689 aa
MADLEAVLADVSYLMAMEKSKATPAARASKKILLPEPSIRSVMQKYLEDRGEVTFEKIFS
QKLGYLLFRDFCLNHLEEAKPLVEFYEEIKKYEKLETEEERVVRSREIFDSYIMKELLAC
SHPFSKNATEHVQGHLVKKQVPPDLFQPYIEEICQNLRGDVFQKFIESDKFTRFCQWKNV
ELNIHLTMNDFSVHRIIGRGGFGEVYGCRKADTGKMYAMKCLDKKRIKMKQGETLALNER
IMLSLVSTGDCPFIVCMSYAFHTPDKLSFILDLMNGGDLHYHLSQHGVFSEADMRFYAAE
IILGLEHMHNRFVVYRDLKPANILLDEHGHVRISDLGLACDFSKKRPHASVGTHGYMAPE
VLQKGVAYDSSADWFSLGCMLFKLLRGHSPFRQHKTKDKHEIDRMTLTMAVELPDSFSPE
LRSLLEGLLQRDVNRRLGCLGRGAQEVKESPFFRSLDWQMVFLQKYPPPLIPPRGEVNAA
DAFDIGSFDEEDTKGIKLLDSDQELYRNFPLTISERWQQEVAETVFDTINAETDRLEARK
KAKNKQLGHEEDYALGKDCIVHGYMSKMGNPFLTQWQRRYFYLFPNRLEWRGEGEAPQSL
LTMEEIQSVEETQIKERKCLLLKIRGGKQFVLQCDSDPELVQWKKELRDAYREAQQLVQR
VPKMKNKPRSPVVELSKVPLIQRGSANGL
NT seq 2070 nt   +upstreamnt  +downstreamnt
atggccgacctggaggcggtgctggccgatgtgagctacctgatggccatggagaagagc
aaggccacgccggccgcgcgcgccagcaagaagatcctgctgccagagcccagcatccgc
agcgtcatgcagaagtatctggaggaccgaggagaagtgacctttgaaaagatcttttcg
cagaagttagggtacctgcttttccgggacttctgcctgaaccatctggaagaggccaag
cccttggtggagttctacgaagagatcaagaaatatgagaagctggagacagaggaggaa
cgtgtggtccgcagccgagagatctttgactcctatattatgaaagaactgctggcctgc
tcacatcccttttcaaagaatgctacggagcatgtccagggccacctggtgaagaagcag
gtgcctccagatctcttccagccatacattgaggagatttgtcagaacctccgaggggac
gtgttccagaagttcatagagagtgacaagttcacacggttctgccagtggaagaatgtt
gagctcaacatccacctgaccatgaatgacttcagtgtgcatcgaatcatcgggcgtggg
ggcttcggtgaggtctatgggtgccggaaagcagacacaggcaagatgtacgccatgaag
tgtctggacaagaaacgcatcaagatgaagcagggagagaccctggctctgaacgagcgg
atcatgctttccctcgtcagcaccggggactgccccttcatcgtgtgcatgtcatatgca
ttccacacaccagacaagctcagcttcatcctggacctcatgaacggtggggacctgcac
taccacctgtctcagcatggagtcttctctgaagccgacatgcgcttctacgccgctgag
atcatcctgggccttgaacacatgcacaatcgctttgtagtctacagggacctgaagcca
gccaacattctcctggatgaacatggccatgtgagaatctcggacctgggcctagcctgt
gacttctccaagaagaggcctcatgccagtgtgggcacacacgggtacatggcccccgaa
gtcctacagaagggcgtggcctatgacagcagtgcagactggttctccctgggctgcatg
ctcttcaagttgttgcggggacacagccccttccggcagcacaagaccaaagacaagcat
gagattgaccgcatgacgttgacgatggctgtagagctgcctgactccttctcccctgaa
ctccgatccctgctggaaggtttgttgcagagggacgtcaatcggagactaggctgtctg
ggccgtggggctcaggaggtaaaagaaagtcctttctttcgttccctggactggcagatg
gtcttcttacagaagtaccctcctccactgatccccccacgtggggaggtgaatgcagct
gacgctttcgacattggctcctttgatgaggaggacacaaaaggaatcaagttactggac
agtgaccaggaactgtaccgcaacttccctctcaccatctctgagcggtggcaacaggag
gtggcagagactgtctttgataccatcaatgctgaaacagaccggctggaggcacgaaag
aaggccaaaaacaaacagctgggccacgaggaggactatgccctgggtaaggactgcatc
gtgcatggctacatgtccaagatgggcaaccccttcctgacccagtggcagcggcgatac
ttctacttgttccccaaccggctcgagtggaggggtgaaggcgaggctccgcagagcctc
ctgaccatggaggagatccagtcagtggaagagacacagatcaaggaacgcaagtgtctc
ctgcttaagatccgaggtggcaagcagtttgtcctgcagtgtgatagtgatccagagctg
gtgcaatggaaaaaggagctgcgtgatgcctaccgcgaggcccagcagctggtacagcga
gtacccaagatgaagaacaagccacgctcgcctgtggtggagctgagcaaggtgccgctg
atccagcgtggcagtgccaacggcctctga

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Ontology (4)   
   KEGG BRITE (4)   
Pathway (6)   
   KEGG PATHWAY (6)   
Chemical reaction (1)   
   KEGG ENZYME (1)   
Genome (1)   
   KEGG GENOME (1)   
Gene (14)   
   KEGG ORTHOLOGY (1)   
   KEGG GENES (1)   
   RefGene (7)   
   NCBI-PROTEINID (1)   
   NCBI-Gene (1)   
   Ensembl (1)   
   RIKEN BRC-DNA (1)   
   OC (1)   
Protein sequence (6)   
   UniProt (2)   
   SWISS-PROT (1)   
   RefSeq(pep) (3)   
DNA sequence (23)   
   RefSeq(nuc) (3)   
   GenBank (10)   
   EMBL (10)   
Protein domain (7)   
   Pfam (7)   
All databases (62)   

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