KEGG   Mus musculus (mouse): 11428
Entry
11428             CDS       T01002                                 

Gene name
Aco1, Aco, Aco-1, I, Ir, Irebp, Irp1
Definition
(RefSeq) aconitase 1
  KO
K01681  aconitate hydratase [EC:4.2.1.3]
Organism
mmu  Mus musculus (mouse)
Pathway
mmu00020  Citrate cycle (TCA cycle)
mmu00630  Glyoxylate and dicarboxylate metabolism
mmu01100  Metabolic pathways
mmu01200  Carbon metabolism
mmu01210  2-Oxocarboxylic acid metabolism
mmu01230  Biosynthesis of amino acids
Module
mmu_M00009  Citrate cycle (TCA cycle, Krebs cycle)
mmu_M00010  Citrate cycle, first carbon oxidation, oxaloacetate => 2-oxoglutarate
Brite
KEGG Orthology (KO) [BR:mmu00001]
 09100 Metabolism
  09101 Carbohydrate metabolism
   00020 Citrate cycle (TCA cycle)
    11428 (Aco1)
   00630 Glyoxylate and dicarboxylate metabolism
    11428 (Aco1)
Enzymes [BR:mmu01000]
 4. Lyases
  4.2  Carbon-oxygen lyases
   4.2.1  Hydro-lyases
    4.2.1.3  aconitate hydratase
     11428 (Aco1)
SSDB
Motif
Pfam: Aconitase Aconitase_C
Other DBs
NCBI-GeneID: 11428
NCBI-ProteinID: NP_031412
MGI: 87879
Ensembl: ENSMUSG00000028405
Vega: OTTMUSG00000006559
UniProt: P28271
Position
4 A5; 4 20.24 cM
AA seq 889 aa
MKNPFAHLAEPLDAAQPGKRFFNLNKLEDSRYGRLPFSIRVLLEAAVRNCDEFLVKKNDI
ENILNWNVMQHKNIEVPFKPARVILQDFTGVPAVVDFAAMRDAVKKLGGNPEKINPVCPA
DLVIDHSIQVDFNRRADSLQKNQDLEFERNKERFEFLKWGSQAFCNMRIIPPGSGIIHQV
NLEYLARVVFDQDGCYYPDSLVGTDSHTTMIDGLGVLGWGVGGIEAEAVMLGQPISMVLP
QVIGYKLMGKPHPLVTSTDIVLTITKHLRQVGVVGKFVEFFGPGVAQLSIADRATIANMC
PEYGATAAFFPVDEVSIAYLLQTGREEDKVKHIQKYLQAVGMFRDFNDTSQDPDFTQVVE
LDLKTVVPCCSGPKRPQDKVAVSEMKKDFESCLGAKQGFKGFQVAPDRHNDRKTFLYSNS
EFTLAHGSVVIAAITSCTNTSNPSVMLGAGLLAKKAVEAGLSVKPYIKTSLSPGSGVVTY
YLRESGVMPYLSQLGFDVVGYGCMTCIGNSGPLPEPVVEAITQGDLVAVGVLSGNRNFEG
RVHPNTRANYLASPPLVIAYAIAGTVRIDFEKEPLGVNAQGRQVFLKDIWPTRDEIQAVE
RQHVIPGMFKEVYQKIETVNKSWNALAAPSEKLYAWNPKSTYIKSPPFFESLTLDLQPPK
SIVDAYVLLNLGDSVTTDHISPAGNIARNSPAARYLTNRGLTPREFNSYGSRRGNDAIMA
RGTFANIRLLNKFLNKQAPQTVHLPSGETLDVFDAAERYQQAGLPLIVLAGKEYGSGSSR
DWAAKGPFLLGIKAVLAESYERIHRSNLVGMGVIPLEYLPGETADSLGLTGRERYTINIP
EDLKPRMTVQIKLDTGKTFQAVMRFDTDVELTYFHNGGILNYMIRKMAQ
NT seq 2670 nt   +upstreamnt  +downstreamnt
atgaagaacccatttgcacaccttgctgagcccttggacgctgcccaaccaggaaagagg
ttcttcaacttgaataaattggaggactcaagatacggacgcttaccattttctatcaga
gttctcctggaggcagccgttcggaactgtgatgagtttctggtgaagaaaaatgacatc
gagaatatcctgaattggaatgtcatgcaacataagaacatagaagtgccgtttaagcca
gcccgagtcatactgcaagactttacgggtgtgcctgctgtggtggattttgcagcaatg
cgcgatgctgtgaagaagttgggagggaatccggagaaaattaaccctgtctgccccgct
gaccttgtaattgatcattccatccaggttgatttcaacagaagggcagacagtttacag
aagaatcaagacctggagtttgaaagaaataaagaacgatttgaatttctaaagtggggt
tcccaggccttttgcaacatgcggataatccctcctggctcgggaatcattcaccaagtg
aacctggagtatttggcaagagtagtgtttgatcaggatggatgctactacccagacagc
ctcgtgggcacagattcacacacgaccatgattgacggcctgggagttcttggttggggt
gtgggtggtattgaagcagaagctgtcatgctgggtcagcccatcagcatggtgcttccc
caggtgattggctacaagctgatggggaagcctcaccctctggtgacatccacggacatc
gtgctcaccattaccaagcacctccgacaagtgggagttgtgggcaaatttgtggagttt
ttcgggccaggagtggctcagctgtccattgctgaccgagctacgattgccaatatgtgc
ccagagtatggtgcgacagcagccttcttcccggttgatgaagttagcatcgcgtacctg
ctgcagacaggccgcgaggaagacaaagtcaagcacattcagaagtatcttcaggctgta
ggcatgtttcgagatttcaacgacacctctcaagacccagacttcactcaggttgtggag
ttagatctgaaaacagttgtgccttgctgcagtggacccaaaagacctcaggacaaagtc
gcggtgtctgagatgaaaaaggactttgaaagctgccttggagccaagcaaggatttaaa
ggtttccaagttgctccagaccgtcacaatgaccgcaagacgttcctctatagtaacagt
gaattcactctcgctcatggctctgtggtaatcgctgccatcactagctgcacaaacacc
agcaatccatccgtgatgttaggagcaggattgttagcaaagaaagctgtggaggcgggg
ctgagtgtgaagccttacatcaaaaccagcctgtctcctggaagtggagtggtcacctac
taccttcgagagagtggagtcatgccttacctgtcccagttagggtttgatgtggtgggc
tacggctgcatgacctgcatcggcaacagtggaccccttcctgaacctgtggtcgaggca
atcacccagggagacctcgtagctgttggcgttctgtctgggaataggaattttgaaggc
cgagtccatcctaacacacgagccaactacttagcatccccccctctggtaatagcatat
gcgattgcaggcaccgtcaggattgacttcgagaaagagcctttgggagtgaacgcacag
ggccggcaagtgtttctgaaggacatctggcccacgcgagatgagatccaggcggtggaa
aggcagcatgtcatccccgggatgtttaaggaggtctatcagaaaatagagactgtaaac
aaaagctggaatgccttagcagccccgtcagagaagctgtatgcgtggaatcccaaatct
acttacattaagtcgccaccattctttgaaagcttgactttagatctccagccacccaag
tccatagtggatgcctatgtgctactgaatttaggagattcagtaacaacggaccatatc
tctcccgccggcaatattgcaagaaacagccctgcggctcgctacttgacgaacagaggc
ctaacaccacgagagttcaactcctatggctcccgccggggtaacgacgccatcatggcc
cgggggacatttgccaacattcgcttgctgaacaagtttctgaacaagcaggcacctcag
actgtccatctcccctcaggagaaacccttgatgtattcgacgctgctgagcggtaccag
caggctggacttcccctgattgttctggctgggaaagaatacggttcaggcagctcccga
gactgggcagccaaaggccctttcctgctgggaatcaaagctgtcctggcagagagctat
gagcgcattcaccgcagcaacttggttggcatgggggtgatcccccttgagtatctccct
ggtgaaactgcagactctctgggactcacaggtcgggaaagatacactatcaacatccct
gaagacctcaagcctcgcatgacggtgcagatcaagctggacactgggaagaccttccag
gccgtgatgaggttcgacactgatgtggagctcacgtacttccacaatggaggcatcctg
aactacatgatccgaaagatggcccagtag

KEGG   Mus musculus (mouse): 11429
Entry
11429             CDS       T01002                                 

Gene name
Aco2, Ac, Aco, Aco-2, Aco3, D10Wsu183, D10Wsu183e
Definition
(RefSeq) aconitase 2, mitochondrial
  KO
K01681  aconitate hydratase [EC:4.2.1.3]
Organism
mmu  Mus musculus (mouse)
Pathway
mmu00020  Citrate cycle (TCA cycle)
mmu00630  Glyoxylate and dicarboxylate metabolism
mmu01100  Metabolic pathways
mmu01200  Carbon metabolism
mmu01210  2-Oxocarboxylic acid metabolism
mmu01230  Biosynthesis of amino acids
Module
mmu_M00009  Citrate cycle (TCA cycle, Krebs cycle)
mmu_M00010  Citrate cycle, first carbon oxidation, oxaloacetate => 2-oxoglutarate
Brite
KEGG Orthology (KO) [BR:mmu00001]
 09100 Metabolism
  09101 Carbohydrate metabolism
   00020 Citrate cycle (TCA cycle)
    11429 (Aco2)
   00630 Glyoxylate and dicarboxylate metabolism
    11429 (Aco2)
Enzymes [BR:mmu01000]
 4. Lyases
  4.2  Carbon-oxygen lyases
   4.2.1  Hydro-lyases
    4.2.1.3  aconitate hydratase
     11429 (Aco2)
SSDB
Motif
Pfam: Aconitase Aconitase_C
Other DBs
NCBI-GeneID: 11429
NCBI-ProteinID: NP_542364
MGI: 87880
Ensembl: ENSMUSG00000022477
Vega: OTTMUSG00000016391
UniProt: Q99KI0
Position
15; 15 E1
AA seq 780 aa
MAPYSLLVTRLQKALGVRQYHVASVLCQRAKVAMSHFEPSEYIRYDLLEKNINIVRKRLN
RPLTLSEKIVYGHLDDPANQEIERGKTYLRLRPDRVAMQDATAQMAMLQFISSGLPKVAV
PSTIHCDHLIEAQVGGEKDLRRAKDINQEVYNFLATAGAKYGVGFWRPGSGIIHQIILEN
YAYPGVLLIGTDSHTPNGGGLGGICIGVGGADAVDVMAGIPWELKCPKVIGVKLTGSLSG
WTSPKDVILKVAGILTVKGGTGAIVEYHGPGVDSISCTGMATICNMGAEIGATTSVFPYN
HRMKKYLSKTGRTDIANLAEEFKDHLVPDPGCQYDQVIEINLNELKPHINGPFTPDLAHP
VADVGTVAEKEGWPLDIRVGLIGSCTNSSYEDMGRSAAVAKQALAHGLKCKSQFTITPGS
EQIRATIERDGYAQILRDVGGIVLANACGPCIGQWDRKDIKKGEKNTIVTSYNRNFTGRN
DANPETHAFVTSPEIVTALAIAGTLKFNPETDFLTGKDGKKFKLEAPDADELPRSDFDPG
QDTYQHPPKDSSGQRVDVSPTSQRLQLLEPFDKWDGKDLEDLQILIKVKGKCTTDHISAA
GPWLKFRGHLDNISNNLLIGAINIENGKANSVRNAVTQEFGPVPDTARYYKKHGIRWVVI
GDENYGEGSSREHAALEPRHLGGRAIITKSFARIHETNLKKQGLLPLTFADPSDYNKIHP
VDKLTIQGLKDFAPGKPLKCVIKHPNGTQETILLNHTFNETQIEWFRAGSALNRMKELQQ
NT seq 2343 nt   +upstreamnt  +downstreamnt
atggcgccttacagcctcctggtcacccggctgcagaaggccctgggtgtgcggcagtac
catgtggcctctgtcctgtgccaacgggccaaggtggccatgagccattttgagcccagt
gagtacatccgatatgacctgctagagaagaacattaacattgtccgtaaacggttgaac
cggcctcttactctctcagagaagattgtatatggacacctggatgacccagccaaccag
gagatcgagcggggaaagacatacctgcgtttacggcccgaccgggtggccatgcaggat
gccacagcccagatggctatgctacagttcattagcagtgggctgcctaaggtggctgta
ccatcaaccatccactgtgatcatctgattgaggcccaggttgggggtgagaaagacctg
cgcagggccaaggacataaaccaggaagtgtataatttcctggcaactgcaggtgccaag
tatggtgtgggcttctggaggcctggatctgggatcattcaccagatcattctagaaaac
tatgcataccctggagttcttctgatcggcactgattcgcacacccccaatggtggtggc
ctgggaggcatctgcattggagtagggggtgctgatgctgtggatgtcatggctgggatc
ccctgggagctgaagtgtcccaaggtgatcggtgtgaagctgacaggctccctctctggt
tggacctcacccaaagatgtgatcctgaaagtggcaggtatcctcacggtgaaaggtggc
acaggtgctattgtggaataccacggacccggtgtcgattccatctcctgcactggcatg
gcaactatctgcaacatgggtgcagaaattggggccactacgtcagtgttcccatacaac
cacaggatgaaaaagtacctgagcaagacaggccgaacagacattgccaacctagcagaa
gaattcaaggatcacttagtgcctgatcctggctgccagtatgaccaagtgattgaaatt
aacctcaatgagctaaagccacatatcaatgggccctttacccctgacttggctcaccca
gtggcagatgtggggactgtggcagagaaggaaggctggcctctggacatcagagtaggt
ttgattggcagctgcaccaattcaagctatgaggacatgggacgatcagcagctgtggct
aagcaggcattggcccacggactcaagtgcaagtcccagttcaccatcaccccaggctct
gagcagatccgtgccactattgagcgggatggctatgcacagatcttaagggatgtgggt
ggaatcgttttggccaatgcctgtggcccttgcatcggccagtgggacagaaaagacatc
aagaagggggagaagaatacaatcgtcacctcttacaacaggaacttcacaggccgtaat
gatgcaaaccctgagacccatgcctttgtcacatccccagagattgtcacagctctggcc
attgcaggaaccctgaagttcaatccagaaactgacttcttaacaggcaaggacggcaag
aagttcaagttggaggctccagatgcagacgagcttccccgatcggactttgatccaggg
caggacacataccagcacccccctaaggacagcagtgggcagcgggtggacgtgagccct
accagccagcgcctgcagctcctggagcctttcgacaagtgggacggcaaagacctcgag
gacctgcaaatcctcatcaaggtcaaagggaagtgcaccacagaccacatttctgctgcc
ggcccctggctcaagttccgtgggcatctggataacatctctaacaacctgctcatcggt
gccatcaacatcgaaaatggcaaagccaactctgtacgcaatgctgtcacccaggagttt
ggccctgtacctgacactgctcgctactacaagaaacatggcatcaggtgggtggtgatt
ggagatgagaactatggtgagggctcaagccgggagcatgcagcactggagcctcgccac
cttgggggccgggccatcatcaccaagagcttcgccaggatccacgaaaccaatctaaag
aagcagggcttgctgcccctcaccttcgctgacccctccgactataacaagattcatcca
gtggacaagctgaccattcaaggcctgaaggactttgcccctggaaagcctctgaagtgc
gtcatcaagcaccccaatgggacccaggagaccatcctcctgaaccacaccttcaacgag
acccagatcgagtggttccgtgcaggcagtgccctcaacaggatgaaggagctgcagcag
tga

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