Entry |
|
Symbol |
Acvr1, ALK2, ActR-I, ActRIA, Acvr, Acvr1a, Acvrlk2, Alk-2, Alk8, D330013D15Rik, SKR1, Tsk7L
|
Name |
(RefSeq) activin A receptor, type 1
|
KO |
|
Organism |
mmu Mus musculus (house mouse)
|
Pathway |
mmu04060 | Cytokine-cytokine receptor interaction |
mmu04550 | Signaling pathways regulating pluripotency of stem cells |
mmu05418 | Fluid shear stress and atherosclerosis |
|
Brite |
KEGG Orthology (KO) [BR:mmu00001]
09130 Environmental Information Processing
09132 Signal transduction
04350 TGF-beta signaling pathway
11477 (Acvr1)
09133 Signaling molecules and interaction
04060 Cytokine-cytokine receptor interaction
11477 (Acvr1)
09140 Cellular Processes
09144 Cellular community - eukaryotes
04550 Signaling pathways regulating pluripotency of stem cells
11477 (Acvr1)
09160 Human Diseases
09166 Cardiovascular disease
05418 Fluid shear stress and atherosclerosis
11477 (Acvr1)
09180 Brite Hierarchies
09181 Protein families: metabolism
01001 Protein kinases [BR:mmu01001]
11477 (Acvr1)
Enzymes [BR:mmu01000]
2. Transferases
2.7 Transferring phosphorus-containing groups
2.7.11 Protein-serine/threonine kinases
2.7.11.30 receptor protein serine/threonine kinase
11477 (Acvr1)
Protein kinases [BR:mmu01001]
Receptor serine/threonine kinases (RSTK): TKL group
TGFBR1 family [OT]
11477 (Acvr1)
|
SSDB |
|
Motif |
|
Other DBs |
|
Position |
2:complement(58336450..58456840)
|
AA seq |
509 aa
MVDGVMILPVLMMMAFPSPSVEDEKPKVNQKLYMCVCEGLSCGNEDHCEGQQCFSSLSIN
DGFHVYQKGCFQVYEQGKMTCKTPPSPGQAVECCQGDWCNRNITAQLPTKGKSFPGTQNF
HLEVGLIILSVVFAVCLLACILGVALRKFKRRNQERLNPRDVEYGTIEGLITTNVGDSTL
AELLDHSCTSGSGSGLPFLVQRTVARQITLLECVGKGRYGEVWRGSWQGENVAVKIFSSR
DEKSWFRETELYNTVMLRHENILGFIASDMTSRHSSTQLWLITHYHEMGSLYDYLQLTTL
DTVSCLRIVLSIASGLAHLHIEIFGTQGKSAIAHRDLKSKNILVKKNGQCCIADLGLAVM
HSQSTNQLDVGNNPRVGTKRYMAPEVLDETIQVDCFDSYKRVDIWAFGLVLWEVARRMVS
NGIVEDYKPPFYDVVPNDPSFEDMRKVVCVDQQRPNIPNRWFSDPTLTSLAKLMKECWYQ
NPSARLTALRIKKTLTKIDNSLDKLKTDC |
NT seq |
1530 nt +upstreamnt +downstreamnt
atggtcgatggagtaatgatccttcctgtgctaatgatgatggctttcccttccccgagt
gtggaagatgagaagcccaaggtcaaccagaaactttacatgtgtgtgtgtgagggcctc
tcctgcgggaacgaggaccactgtgaaggccagcagtgtttttcttctctgagcatcaac
gatggcttccacgtctaccagaagggctgctttcaggtttatgagcaggggaagatgacg
tgtaagaccccgccgtcacctggccaggctgtggagtgctgccaaggggactggtgtaac
aggaacatcacggcccagctgcccactaaagggaagtccttccccggaacacagaatttc
cacctggaagttggccttatcatcctctcggtggtgtttgcagtatgtcttttagcttgc
atccttggagttgctctcaggaagtttaagagacgcaatcaagagcgcctgaaccccaga
gacgtggagtatggtaccattgaagggctcatcaccaccaatgtgggagacagcactcta
gcggaactactagatcactcgtgtacatcaggaagtggctccggtcttcctttcctggta
cagagaacggtggctcgccagataaccctgttggagtgtgtcgggaagggccggtatgga
gaagtatggaggggcagctggcaaggcgaaaatgtcgctgtgaagatcttctcctcccga
gacgagaagtcatggttcagggagacggaattgtacaacactgtgatgttgaggcatgaa
aatatcttaggtttcatcgcttcagacatgacctccagacactccagtacccagctgtgg
ctcatcacacattaccatgaaatgggatcgttgtatgactaccttcagctcactactctg
gatacggttagctgccttcggattgtactgtccatagccagcggccttgcccatttgcac
atagagatatttgggacccaagggaagtccgccattgcccatcgagatctgaagagcaaa
aacatcctggtgaagaagaatggacagtgctgcatagcagatttgggcctggcagtcatg
cattcccagagcacaaaccagcttgatgtgggaaacaacccccgtgtggggaccaagcgc
tacatggctccggaagtgctcgatgaaaccatccaagtggattgctttgattcttataag
agggtcgatatttgggcctttggccttgttctgtgggaagtggccaggcgaatggtgagc
aatggtatagtggaagattacaagccaccattctatgatgtggttcccaatgacccaagt
tttgaagatatgaggaaagttgtctgtgtggatcaacagaggccaaacatacctaacaga
tggttctcagacccgacattaacttctctggcgaagctgatgaaagagtgctggtatcag
aacccatccgcaagactcacagctctacgtatcaaaaagactttgaccaaaatcgataat
tccctagacaaattaaaaactgactgttga |