KEGG   Mus musculus (mouse): 11772Help
Entry
11772             CDS       T01002                                 

Gene name
Ap2a2, 2410074K14Rik, AF006990, AW146353, Adtab, C78001, L25
Definition
(RefSeq) adaptor-related protein complex 2, alpha 2 subunit
  KO
K11824  AP-2 complex subunit alpha
Organism
mmu  Mus musculus (mouse)
Pathway
mmu04144  Endocytosis
mmu04721  Synaptic vesicle cycle
mmu04961  Endocrine and other factor-regulated calcium reabsorption
mmu05016  Huntington disease
Brite
KEGG Orthology (KO) [BR:mmu00001]
 09140 Cellular Processes
  09141 Transport and catabolism
   04144 Endocytosis
    11772 (Ap2a2)
 09150 Organismal Systems
  09155 Excretory system
   04961 Endocrine and other factor-regulated calcium reabsorption
    11772 (Ap2a2)
  09156 Nervous system
   04721 Synaptic vesicle cycle
    11772 (Ap2a2)
 09160 Human Diseases
  09164 Neurodegenerative disease
   05016 Huntington disease
    11772 (Ap2a2)
 09180 Brite Hierarchies
  09182 Protein families: genetic information processing
   04131 Membrane trafficking [BR:mmu04131]
    11772 (Ap2a2)
  09183 Protein families: signaling and cellular processes
   04147 Exosome [BR:mmu04147]
    11772 (Ap2a2)
Membrane trafficking [BR:mmu04131]
 Endocytosis
  Clathrin-mediated endocytosis
   AP-2 complex
    11772 (Ap2a2)
Exosome [BR:mmu04147]
 Exosomal proteins
  Exosomal proteins of colorectal cancer cells
   11772 (Ap2a2)
BRITE hierarchy
SSDB OrthologParalogGFIT
Motif
Pfam: Adaptin_N Alpha_adaptin_C Alpha_adaptinC2 Cnd1 HEAT_2 RIX1 IFRD
Motif
Other DBs
NCBI-GeneID: 11772
NCBI-ProteinID: NP_031485
MGI: 101920
Ensembl: ENSMUSG00000002957
Vega: OTTMUSG00000055665
UniProt: P17427 Q6PEE6 Q69ZW4
Structure
PDB: 

Position
7; 7 F5
AA seq 938 aa AA seqDB search
MPAVSKGDGMRGLAVFISDIRNCKSKEAEIKRINKELANIRSKFKGDKALDGYSKKKYVC
KLLFIFLLGHDIDFGHMEAVNLLSSNRYTEKQIGYLFISVLVNSNSELIRLINNAIKNDL
ASRNPTFMGLALHCIANVGSREMAEAFAGEIPKILVAGDTMDSVKQSAALCLLRLYRTSP
DLVPMGDWTSRVVHLLNDQHLGVVTAATSLITTLAQKNPEEFKTSVSLAVSRLSRIVTSA
STDLQDYTYYFVPAPWLSVKLLRLLQCYPPPDPAVRGRLTECLETILNKAQEPPKSKKVQ
HSNAKNAVLFEAISLIIHHDSEPNLLVRACNQLGQFLQHRETNLRYLALESMCTLASSEF
SHEAVKTHIETVINALKTERDVSVRQRAVDLLYAMCDRSNAQQIVAEMLSYLETADYSIR
EEIVLKVAILAEKYAVDYTWYVDTILNLIRIAGDYVSEEVWYRVIQIVINRDDVQGYAAK
TVFEALQAPACHENLVKVGGYILGEFGNLIAGDPRSSPLIQFNLLHSKFHLCSVPTRALL
LSTYIKFVNLFPEVKATIQDVLRSDSQLKNADVELQQRAVEYLRLSTVASTDILATVLEE
MPPFPERESSILAKLKKKKGPSTVTDLEETKRERSIDVNGGPEPVPASTSAASTPSPSAD
LLGLGAVPPAPTGPPPSSGGGLLVDVFSDSASAVAPLAPGSEDNFARFVCKNNGVLFENQ
LLQIGLKSEFRQNLGRMFIFYGNKTSTQFLNFTPTLICADDLQTNLNLQTKPVDPTVDGG
AQVQQVVNIECISDFTEAPVLNIQFRYGGTFQNVSVKLPITLNKFFQPTEMASQDFFQRW
KQLSNPQQEVQNIFKAKHPMDTEITKAKIIGFGSALLEEVDPNPANFVGAGIIHTKTTQI
GCLLRLEPNLQAQMYRLTLRTSKDTVSQRLCELLSEQF
NT seq 2817 nt NT seq  +upstreamnt  +downstreamnt
atgccggccgtatccaagggggacgggatgcgaggcctagcggtcttcatctccgacatc
cgcaactgtaaaagtaaagaagctgaaataaagagaataaacaaagaactggcaaatatt
agatccaaatttaaaggtgacaaggctcttgatggctacagtaaaaagaagtatgtctgc
aaattgctcttcatctttctccttggtcatgacattgactttggacacatggaagctgtg
aatcttctgagctcaaacagatacacggaaaagcagattggctaccttttcatctctgta
ttggtgaactcgaatagtgaactgatccggttgattaacaatgccatcaagaatgacctg
gccagccgcaatcctacgtttatgggtctcgccctgcactgcattgccaatgtgggtagc
cgtgagatggcggaggccttcgccggagagatccccaagatcctcgtggcaggagatacc
atggatagtgtgaagcagagcgcagccctgtgcttgttacgcctgtacaggacatcacct
gacctagttcccatgggcgactggacatctcgtgtggtacacctcctcaatgaccagcac
ttgggggtagtgactgcagcgactagcctcatcaccaccctggcccagaagaaccctgag
gagttcaagacctctgtctcgctagctgtctcgcgactgagcaggattgtgacgtctgca
tcaacagatcttcaggattatacttactactttgtcccggctccttggctgtcagtcaag
cttctgagactgctgcagtgctacccacccccagaccctgcggtgcgtggccgcctgact
gagtgcttggagaccatcctgaacaaggcccaggagccacccaagtccaagaaggtccag
cattcaaatgccaagaacgctgtgctgtttgaggccatcagcctgatcatccaccatgac
agtgagccaaacttgctcgtccgcgcctgcaaccagctgggccagttcctgcagcaccgg
gagacgaacctacgctacctggctctggagagcatgtgcacgctggccagctctgagttc
tcccacgaggccgtcaagacccacattgagacggtcatcaatgccttgaagacggaaaga
gacgtgagtgtgaggcagcgggcagtggacctgctctacgccatgtgtgaccggagcaac
gcccagcagattgtggctgagatgctgagctacctagaaacggctgactactccatccga
gaggaaattgtgctgaaggtggccatcctggctgagaagtatgcagtggactacacttgg
tatgtggacaccatcctcaacctcatccgcatcgcgggcgactatgtgagcgaggaggtg
tggtaccgcgtcatccagattgtcatcaatcgcgatgatgtgcagggctatgctgccaag
acggtatttgaggcattgcaggcgccagcatgtcatgagaacttggtcaaagtgggcggc
tacatcctgggggagtttggaaacttgatagctggggacccacgatccagccctctgatc
cagttcaacctgctccactccaagttccacttgtgcagcgtccccactcgggcactcctg
ctgtccacctacatcaagttcgtgaacctctttccagaggtaaaagctaccattcaggac
gtgctgcgcagtgacagccagctgaagaatgccgacgtggagctgcagcagcgggctgtg
gagtacctgcgactgagcactgtcgccagcactgacatcctggcaactgtcctggaggaa
atgccacccttccctgagcgtgagtcctccatcttggccaagctgaagaagaagaagggc
ccaagcacagtgactgacctggaggagaccaagcgggagcgaagcatcgatgtgaatggg
ggccctgaacccgttccagccagcaccagtgctgcgtccacaccttctccgtcagcagac
ctgctgggtctgggggccgtgccccctgctcccacggggccccctccctcctctggcggc
gggctgctggtggacgtgttctcagactcagcttctgcagtcgcacctcttgcacccggc
tctgaagacaactttgccaggtttgtttgtaaaaataatggtgtattgttcgaaaaccag
ctgcttcaaattggacttaagtcagaatttcggcagaatttaggccgaatgttcatattt
tatggtaacaagacctccacgcagttcctaaacttcactccaacactaatctgtgctgac
gaccttcaaactaatctgaacctgcagactaagcccgtggacccaactgtggatgggggc
gcacaggtgcaacaagtggtcaacattgagtgtatatctgatttcacagaggcacctgtc
ctcaacatccagttcaggtatggtgggaccttccagaatgtgtctgttaagcttcccatc
actctcaacaaatttttccagcccacagaaatggcttctcaggatttctttcaacgttgg
aagcagttgagcaatccacagcaagaagtgcagaatatcttcaaagcaaagcatccgatg
gacacagagatcactaaggcaaagattattggatttggttctgcgctcctggaagaagtt
gacccgaatcctgcaaatttcgtgggtgctggcataatacacaccaaaaccacccagatt
ggctgcttgttgcgcctggagccaaacctgcaagctcagatgtatagactcaccttgcgt
accagcaaagacaccgtctctcagagactatgtgaattgctgtcggaacagttctag

DBGET integrated database retrieval system