KEGG   Mus musculus (house mouse): 11937
Entry
11937             CDS       T01002                                 
Symbol
Atp2a1, SERCA1
Name
(RefSeq) ATPase, Ca++ transporting, cardiac muscle, fast twitch 1
  KO
K05853  P-type Ca2+ transporter type 2A [EC:7.2.2.10]
Organism
mmu  Mus musculus (house mouse)
Pathway
mmu04020  Calcium signaling pathway
mmu04022  cGMP-PKG signaling pathway
mmu04024  cAMP signaling pathway
mmu04148  Efferocytosis
mmu04260  Cardiac muscle contraction
mmu04261  Adrenergic signaling in cardiomyocytes
mmu04380  Osteoclast differentiation
mmu04919  Thyroid hormone signaling pathway
mmu04972  Pancreatic secretion
mmu05010  Alzheimer disease
mmu05017  Spinocerebellar ataxia
mmu05022  Pathways of neurodegeneration - multiple diseases
mmu05410  Hypertrophic cardiomyopathy
mmu05412  Arrhythmogenic right ventricular cardiomyopathy
mmu05414  Dilated cardiomyopathy
mmu05415  Diabetic cardiomyopathy
Brite
KEGG Orthology (KO) [BR:mmu00001]
 09130 Environmental Information Processing
  09132 Signal transduction
   04020 Calcium signaling pathway
    11937 (Atp2a1)
   04024 cAMP signaling pathway
    11937 (Atp2a1)
   04022 cGMP-PKG signaling pathway
    11937 (Atp2a1)
 09140 Cellular Processes
  09141 Transport and catabolism
   04148 Efferocytosis
    11937 (Atp2a1)
 09150 Organismal Systems
  09152 Endocrine system
   04919 Thyroid hormone signaling pathway
    11937 (Atp2a1)
  09153 Circulatory system
   04260 Cardiac muscle contraction
    11937 (Atp2a1)
   04261 Adrenergic signaling in cardiomyocytes
    11937 (Atp2a1)
  09154 Digestive system
   04972 Pancreatic secretion
    11937 (Atp2a1)
  09158 Development and regeneration
   04380 Osteoclast differentiation
    11937 (Atp2a1)
 09160 Human Diseases
  09164 Neurodegenerative disease
   05010 Alzheimer disease
    11937 (Atp2a1)
   05017 Spinocerebellar ataxia
    11937 (Atp2a1)
   05022 Pathways of neurodegeneration - multiple diseases
    11937 (Atp2a1)
  09166 Cardiovascular disease
   05410 Hypertrophic cardiomyopathy
    11937 (Atp2a1)
   05412 Arrhythmogenic right ventricular cardiomyopathy
    11937 (Atp2a1)
   05414 Dilated cardiomyopathy
    11937 (Atp2a1)
   05415 Diabetic cardiomyopathy
    11937 (Atp2a1)
Enzymes [BR:mmu01000]
 7. Translocases
  7.2  Catalysing the translocation of inorganic cations
   7.2.2  Linked to the hydrolysis of a nucleoside triphosphate
    7.2.2.10  P-type Ca2+ transporter
     11937 (Atp2a1)
SSDB
Motif
Pfam: E1-E2_ATPase Cation_ATPase_C Cation_ATPase Cation_ATPase_N Hydrolase Hydrolase_3 HAD CA109-like
Other DBs
NCBI-GeneID: 11937
NCBI-ProteinID: NP_031530
MGI: 105058
Ensembl: ENSMUSG00000030730
UniProt: Q8R429
Position
7:complement(126045032..126062245)
AA seq 994 aa
MEAAHSKSTEECLSYFGVSETTGLTPDQVKRHLEKYGPNELPAEEGKSLWELVVEQFEDL
LVRILLLAACISFVLAWFEEGEETVTAFVEPFVILLILIANAIVGVWQERNAENAIEALK
EYEPEMGKVYRADRKSVQRIKARDIVPGDIVEVAVGDKVPADIRILSIKSTTLRVDQSIL
TGESVSVIKHTDPVPDPRAVNQDKKNMLFSGTNIAAGKAVGIVATTGVSTEIGKIRDQMA
ATEQDKTPLQQKLDEFGEQLSKVISLICVAVWLINIGHFNDPVHGGSWFRGAIYYFKIAV
ALAVAAIPEGLPAVITTCLALGTRRMAKKNAIVRSLPSVETLGCTSVICSDKTGTLTTNQ
MSVCKMFIIDKVDGDVCSLNEFSITGSTYAPEGEVLKNDKPVRAGQYDGLVELATICALC
NDSSLDFNETKGVYEKVGEATETALTTLVEKMNVFNTEVRSLSKVERANACNSVIRQLMK
KEFTLEFSRDRKSMSVYCSPAKSSRAAVGNKMFVKGAPEGVIDRCNYVRVGTTRVPLTGP
VKEKIMSVIKEWGTGRDTLRCLALATRDTPPKREEMVLDDSAKFMEYEMDLTFVGVVGML
DPPRKEVTGSIQLCRDAGIRVIMITGDNKGTAIAICRRIGIFSENEEVTDRAYTGREFDD
LPLAEQREACRRACCFARVEPSHKSKIVEYLQSYDEITAMTGDGVNDAPALKKAEIGIAM
GSGTAVAKTASEMVLADDNFSTIVAAVEEGRAIYNNMKQFIRYLISSNVGEVVCIFLTAA
LGLPEALIPVQLLWVNLVTDGLPATALGFNPPDLDIMDRPPRSPKEPLISGWLFFRYMAI
GGYVGAATVGAAAWWFLYAEDGPHVSYHQLTHFMQCTEHNPEFDGLDCEVFEAPEPMTMA
LSVLVTIEMCNALNSLSENQSLLRMPPWVNIWLLGSICLSMSLHFLILYVDPLPMIFKLR
ALDFTQWLMVLKISLPVIGLDELLKFIARNYLEG
NT seq 2985 nt   +upstreamnt  +downstreamnt
atggaggccgcgcactccaagtccacagaggaatgtttgtcctatttcggggtgagcgag
accacaggccttaccccagaccaagttaagcgacatctggaaaaatacggccccaatgag
ctccctgctgaggaaggcaagtctctgtgggagttggtggtagagcagttcgaagacctg
cttgtgcggattcttctcctggctgcctgcatttcctttgtgctggcctggtttgaggaa
ggcgaagaaaccgtcactgcctttgtggaaccttttgtcattctcttgatcctcattgcc
aacgccattgtgggggtttggcaggaacggaatgcagagaacgctatcgaagcgctgaaa
gaatatgaacccgagatgggaaaggtctatcgggctgaccgaaagtcagtgcaaaggatc
aaggctcgggacatcgttcctggggacatcgtggaggtggccgttggggacaaagtccct
gcagacatccgcatcctctccatcaaatccaccaccctccgggtcgaccagtccatcctg
acaggagagtctgtgtctgtcatcaagcacacagaccctgtccctgacccccgagctgtc
aaccaggacaagaagaacatgctcttctcaggtaccaacatcgcagccggcaaggctgta
ggcatcgtggccaccactggtgtgagtactgagattggcaagatccgagaccagatggct
gccaccgagcaggacaagactccactgcagcagaagcttgacgagtttggggagcagctg
tccaaggtcatctctctcatctgtgtggctgtctggcttatcaacattggccacttcaac
gatcctgtccatgggggctcctggttccggggtgccatttactacttcaagattgctgtg
gccttggctgtggcggccatcccagaagggcttcctgctgtcatcaccacctgcttggct
ttgggtacccgccggatggcaaagaagaacgccatcgtgaggagtctgccctctgtggag
accctgggctgtacctctgtcatctgttctgacaaaacagggaccctcaccaccaaccag
atgtcagtttgcaagatgttcatcattgacaaggtggatggggatgtctgctcactgaac
gagttctccatcactggctctacttatgctcctgagggagaggtcttgaagaatgataag
ccagtccgagcagggcagtatgatgggctggtggagctcgctaccatctgtgccctctgc
aatgattcctccttggactttaatgagaccaaaggtgtctatgagaaggtgggcgaggcc
acggagactgctctcaccaccttggtggagaagatgaacgtattcaacacggaagtgaga
agcctctctaaagtggagcgggccaacgcctgcaattcggtgatccgccaactcatgaag
aaggaattcaccctggaattttcccgagacaggaagtctatgtctgtctactgttcacca
gctaagtcctcacgggctgccgtgggcaacaagatgtttgtcaagggtgcccccgagggg
gtcatcgaccgctgtaactatgtgcgtgttggcacgacccgtgtgccattgacaggcccc
gtgaaggagaagatcatgtctgtgatcaaggagtggggcactggtcgggacacactgcgg
tgcctggcgctggccacccgcgacacgccccccaaacgcgaggagatggttctggatgat
tcagccaagttcatggagtatgagatggacctgacgtttgttggtgttgtgggcatgttg
gatccaccccgcaaggaggtcacaggctctatccagctgtgtcgtgatgctgggatccga
gtgatcatgatcactggggacaacaagggtacagccattgccatctgccgacgaattggc
atcttttcggagaatgaggaagtgacagaccgtgcctacactggccgtgagtttgacgat
ctgcccctggccgagcagcgggaggcctgcagacgcgcctgctgctttgctcgtgtggag
ccctcacacaagtccaagattgtggagtacctgcagtcctacgatgagatcacagccatg
acaggggatggtgtcaatgatgcccctgctctgaagaaggccgagattggcattgccatg
ggatctggtactgctgtggctaagacggcctctgaaatggtactggccgatgataacttc
tccaccatcgtggctgccgtggaggaaggccgcgccatctacaacaacatgaagcagttc
atccgctacctcatctcctccaatgtgggcgaggtggtctgtatcttcttgacagcagcc
ttggggctgcctgaggctctgatccctgtgcagctgctctgggtgaacttggtgactgat
gggctcccggctactgccctgggattcaacccacctgacctggacatcatggaccgcccc
cccaggagtcccaaggagcctcttatcagtggctggctctttttccgctacatggcaatt
gggggctatgtgggtgcagccactgtaggagcagctgcctggtggtttttgtatgcagag
gacgggcctcatgtcagctaccatcagctgactcatttcatgcagtgcactgagcacaac
cctgaattcgatggcctggactgtgaggtctttgaggcccccgagcccatgaccatggcc
ttgtctgtgttggtgaccatcgagatgtgcaatgctctcaacagcctgtctgagaaccag
tccctactgcggatgccaccctgggtgaacatctggctgctgggttccatctgcctgtcc
atgtccctccacttcctcatcctctatgtcgaccccctgccgatgatcttcaagctccgg
gccctggactttacccagtggctcatggtcctcaagatctcactgccagtcatcgggctg
gatgagcttctcaagttcattgctcggaactatctggagggataa

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Ontology (2)   
   KEGG BRITE (2)   
Pathway (16)   
   KEGG PATHWAY (16)   
Chemical reaction (1)   
   KEGG ENZYME (1)   
Genome (1)   
   KEGG GENOME (1)   
Gene (21)   
   KEGG ORTHOLOGY (1)   
   KEGG GENES (1)   
   RefGene (14)   
   NCBI-PROTEINID (1)   
   NCBI-Gene (1)   
   Ensembl (1)   
   RIKEN BRC-DNA (1)   
   OC (1)   
Protein sequence (3)   
   UniProt (1)   
   SWISS-PROT (1)   
   RefSeq(pep) (1)   
DNA sequence (11)   
   RefSeq(nuc) (1)   
   GenBank (5)   
   EMBL (5)   
Protein domain (8)   
   Pfam (8)   
All databases (63)   

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