KEGG   Mus musculus (mouse): 12005Help
Entry
12005             CDS       T01002                                 

Gene name
Axin1, AI316800, Axin, Fu, Kb, Ki, fused, kinky, knobbly
Definition
(RefSeq) axin 1
  KO
K02157  axin 1
Organism
mmu  Mus musculus (mouse)
Pathway
mmu04310  Wnt signaling pathway
mmu04390  Hippo signaling pathway
mmu04550  Signaling pathways regulating pluripotency of stem cells
mmu04934  Cushing syndrome
mmu05165  Human papillomavirus infection
mmu05200  Pathways in cancer
mmu05210  Colorectal cancer
mmu05213  Endometrial cancer
mmu05217  Basal cell carcinoma
mmu05224  Breast cancer
mmu05225  Hepatocellular carcinoma
mmu05226  Gastric cancer
Brite
KEGG Orthology (KO) [BR:mmu00001]
 09130 Environmental Information Processing
  09132 Signal transduction
   04310 Wnt signaling pathway
    12005 (Axin1)
   04390 Hippo signaling pathway
    12005 (Axin1)
 09140 Cellular Processes
  09144 Cellular community - eukaryotes
   04550 Signaling pathways regulating pluripotency of stem cells
    12005 (Axin1)
 09160 Human Diseases
  09161 Cancers: Overview
   05200 Pathways in cancer
    12005 (Axin1)
  09162 Cancers: Specific types
   05210 Colorectal cancer
    12005 (Axin1)
   05225 Hepatocellular carcinoma
    12005 (Axin1)
   05226 Gastric cancer
    12005 (Axin1)
   05217 Basal cell carcinoma
    12005 (Axin1)
   05213 Endometrial cancer
    12005 (Axin1)
   05224 Breast cancer
    12005 (Axin1)
  09167 Endocrine and metabolic diseases
   04934 Cushing syndrome
    12005 (Axin1)
  09172 Infectious diseases: Viral
   05165 Human papillomavirus infection
    12005 (Axin1)
 09180 Brite Hierarchies
  09181 Protein families: metabolism
   01009 Protein phosphatases and associated proteins [BR:mmu01009]
    12005 (Axin1)
Protein phosphatases and associated proteins [BR:mmu01009]
 Protein Ser/ Thr phosphatases
  Phosphoprotein phosphatases (PPPs)
   Protein phosphatase-1
    PP1-interacting proteins (PIPs)
     12005 (Axin1)
BRITE hierarchy
SSDB OrthologParalogGFIT
Motif
Pfam: DIX RGS AXIN1_TNKS_BD Axin_b-cat_bind
Motif
Other DBs
NCBI-GeneID: 12005
NCBI-ProteinID: NP_033863
MGI: 1096327
Ensembl: ENSMUSG00000024182
Vega: OTTMUSG00000026498
UniProt: O35625 E9QMJ8
Structure
PDB: 

Position
17 A3.3; 17 13.07 cM
AA seq 868 aa AA seqDB search
MQSPKMNVQEQGFPLDLGASFTEDAPRPPVPGEEGELVSTDSRPVNHSFCSGKGTSIKSE
TSTATPRRSDLDLGYEPEGSASPTPPYLRWAESLHSLLDDQDGISLFRTFLKQEGCADLL
DFWFACSGFRKLEPCDSNEEKRLKLARAIYRKYILDSNGIVSRQTKPATKSFIKDCVMKQ
QIDPAMFDQAQTEIQSTMEENTYPSFLKSDIYLEYTRTGSESPKVCSDQSSGSGTGKGMS
GYLPTLNEDEEWKCDQDADEDDGRDPLPPSRLTQKLLLETAAPRAPSSRRYNEGRELRYG
SWREPVNPYYVNSGYALAPATSANDSEQQSLSSDADTLSLTDSSVDGIPPYRIRKQHRRE
MQESIQVNGRVPLPHIPRTYRMPKEIRVEPQKFAEELIHRLEAVQRTREAEEKLEERLKR
VRMEEEGEDGEMPSGPMASHKLPSVPAWHHFPPRYVDMGCSGLRDAHEENPESILDEHVQ
RVMRTPGCQSPGPGHRSPDSGHVAKTAVLGGTASGHGKHVPKLGLKLDTAGLHHHRHVHH
HVHHNSARPKEQMEAEVARRVQSSFSWGPETHGHAKPRSYSENAGTTLSAGDLAFGGKTS
APSKRNTKKAESGKNANAEVPSTTEDAEKNQKIMQWIIEGEKEISRHRKAGHGSSGLRKQ
QAHESSRPLSIERPGAVHPWVSAQLRNSVQPSHLFIQDPTMPPNPAPNPLTQLEEARRRL
EEEEKRANKLPSKQRYVQAVMQRGRTCVRPACAPVLSVVPAVSDLELSETETKSQRKAGG
GSAPPCDSIVVAYYFCGEPIPYRTLVRGRAVTLGQFKELLTKKGSYRYYFKKVSDEFDCG
VVFEEVREDEAVLPVFEEKIIGKVEKVD
NT seq 2607 nt NT seq  +upstreamnt  +downstreamnt
atgcagagtcccaaaatgaatgtccaggagcagggtttccccttggacctcggagcaagt
ttcaccgaagatgccccccggcccccagtgcctggagaagagggagaactggtatctact
gattcgaggcctgtcaaccacagtttctgttctgggaaaggtaccagcattaaaagtgag
acctcaacagccaccccaagacgttcagatctggatctgggatatgagcccgagggcagt
gcctcccccaccccaccatatttgaggtgggctgagtcactgcattccttactggatgac
caagatgggatcagcctgttcaggactttcctgaagcaggagggctgtgctgacctgctg
gacttctggtttgcctgcagtggcttcaggaagcttgagccctgtgactcaaatgaggaa
aagaggctgaagctggcaagagccatctaccgaaagtacatcctggatagcaatggcatt
gtgtccagacaaaccaagccagccactaagagcttcataaaggactgtgtcatgaagcag
cagatagatcctgccatgtttgaccaggcacagacagaaatccagtccaccatggaggag
aatacctacccttcctttcttaagtctgacatttatttggagtacacaaggacaggctca
gagagtccgaaggtctgcagtgaccagagctcagggtctggaacagggaagggcatgtct
ggatacctgcccactttgaatgaggatgaagaatggaaatgtgaccaagatgcagatgag
gatgatggccgagaccctctcccccccagcaggctcacccagaagctgctattggagact
gctgccccgagggccccctcaagtagacggtacaacgaaggcagagagctcaggtatgga
tcttggagggagcccgtcaacccctactacgtcaactctggctatgccctggccccagcc
accagtgccaatgacagtgagcagcagagcctgtccagtgatgctgacacgctatccctt
acggacagtagtgtggatggaatccccccatacaggatccgtaagcagcaccgaagggag
atgcaggagagtatccaagtcaatgggcgggtacctctacctcacattcctcgcacttac
cgaatgccaaaggagatccgggtagagccacagaaatttgctgaagagcttattcaccgt
ctagaggctgtccagcgcactcgagaggctgaagaaaagttggaggaacggctgaagcgt
gtacgcatggaggaagaaggggaggatggtgaaatgccttctggccccatggcaagtcac
aagctgccttctgtcccagcttggcaccatttcccaccccgctatgtggatatgggctgc
tctggactgcgggatgcccatgaggagaatcctgagagcatcctggatgagcacgtgcaa
agggtcatgaggacacctggctgccagtcacctggcccaggccaccgctctcctgacagt
gggcatgtggctaagactgcagtgctagggggtacagcctccgggcatgggaagcatgtt
cctaagttagggttgaagctggatacagctggcctgcaccatcatagacatgtccaccac
catgttcaccataattcagctagacctaaggagcaaatggaggctgaagttgcccgcagg
gtccagagcagcttctcgtggggcccagaaacacatggtcatgccaagccccggagctat
tccgagaacgcaggcaccaccctcagtgctggggatttggcctttggtggtaaaactagt
gcaccttccaaaagaaacaccaagaaggctgaatctgggaagaatgccaatgctgaggta
cccagtaccacagaggacgctgagaagaaccagaagatcatgcagtggatcattgaggga
gagaaggagatcagtagacaccggaaggcaggccatgggtcttctgggttgaggaagcag
caggcccatgaaagctccaggcccttgtccatcgagcgtcctggggccgtgcacccctgg
gtcagcgctcagcttcggaattctgtccagccttctcatcttttcatccaagatcccaca
atgccacccaatccagcccctaatcccctgacccagctggaagaggcccgcaggcgtttg
gaagaagaagaaaagagagcaaacaaactgccctccaagcagaggtatgtgcaggcagtc
atgcagcggggacgcacctgtgtcaggccagcttgtgcaccggtgctgagtgtggtacca
gccgtgtcggacttggaactctccgagacagagacaaaatcacaaagaaaggcaggtggc
gggagtgcaccaccatgtgacagcattgttgtggcctactatttctgtggggaacccatc
ccctaccggaccctggtgaggggccgtgctgtcaccctgggccagttcaaggagctgcta
accaagaaggggagctacagatactactttaagaaagtgagtgatgagtttgactgtggt
gtggtatttgaggaagtacgggaggatgaggccgtcttgcctgtctttgaagaaaagatc
atcggcaaggtggaaaaggtggactga

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