KEGG   Mus musculus (house mouse): 12043
Entry
12043             CDS       T01002                                 
Symbol
Bcl2, Bcl-2, C430015F12Rik, D630044D05Rik, D830018M01Rik
Name
(RefSeq) B cell leukemia/lymphoma 2
  KO
K02161  apoptosis regulator Bcl-2
Organism
mmu  Mus musculus (house mouse)
Pathway
mmu01521  EGFR tyrosine kinase inhibitor resistance
mmu01522  Endocrine resistance
mmu01524  Platinum drug resistance
mmu04064  NF-kappa B signaling pathway
mmu04066  HIF-1 signaling pathway
mmu04071  Sphingolipid signaling pathway
mmu04115  p53 signaling pathway
mmu04140  Autophagy - animal
mmu04141  Protein processing in endoplasmic reticulum
mmu04151  PI3K-Akt signaling pathway
mmu04210  Apoptosis
mmu04215  Apoptosis - multiple species
mmu04217  Necroptosis
mmu04261  Adrenergic signaling in cardiomyocytes
mmu04340  Hedgehog signaling pathway
mmu04510  Focal adhesion
mmu04621  NOD-like receptor signaling pathway
mmu04630  JAK-STAT signaling pathway
mmu04722  Neurotrophin signaling pathway
mmu04725  Cholinergic synapse
mmu04915  Estrogen signaling pathway
mmu04928  Parathyroid hormone synthesis, secretion and action
mmu04933  AGE-RAGE signaling pathway in diabetic complications
mmu05014  Amyotrophic lateral sclerosis
mmu05022  Pathways of neurodegeneration - multiple diseases
mmu05132  Salmonella infection
mmu05145  Toxoplasmosis
mmu05152  Tuberculosis
mmu05161  Hepatitis B
mmu05162  Measles
mmu05168  Herpes simplex virus 1 infection
mmu05169  Epstein-Barr virus infection
mmu05170  Human immunodeficiency virus 1 infection
mmu05200  Pathways in cancer
mmu05206  MicroRNAs in cancer
mmu05207  Chemical carcinogenesis - receptor activation
mmu05210  Colorectal cancer
mmu05215  Prostate cancer
mmu05222  Small cell lung cancer
mmu05226  Gastric cancer
mmu05417  Lipid and atherosclerosis
mmu05418  Fluid shear stress and atherosclerosis
Brite
KEGG Orthology (KO) [BR:mmu00001]
 09120 Genetic Information Processing
  09123 Folding, sorting and degradation
   04141 Protein processing in endoplasmic reticulum
    12043 (Bcl2)
 09130 Environmental Information Processing
  09132 Signal transduction
   04630 JAK-STAT signaling pathway
    12043 (Bcl2)
   04064 NF-kappa B signaling pathway
    12043 (Bcl2)
   04066 HIF-1 signaling pathway
    12043 (Bcl2)
   04071 Sphingolipid signaling pathway
    12043 (Bcl2)
   04151 PI3K-Akt signaling pathway
    12043 (Bcl2)
 09140 Cellular Processes
  09141 Transport and catabolism
   04140 Autophagy - animal
    12043 (Bcl2)
  09143 Cell growth and death
   04215 Apoptosis - multiple species
    12043 (Bcl2)
 09150 Organismal Systems
  09152 Endocrine system
   04915 Estrogen signaling pathway
    12043 (Bcl2)
   04928 Parathyroid hormone synthesis, secretion and action
    12043 (Bcl2)
  09156 Nervous system
   04725 Cholinergic synapse
    12043 (Bcl2)
   04722 Neurotrophin signaling pathway
    12043 (Bcl2)
 09160 Human Diseases
  09161 Cancer: overview
   05200 Pathways in cancer
    12043 (Bcl2)
   05206 MicroRNAs in cancer
    12043 (Bcl2)
   05207 Chemical carcinogenesis - receptor activation
    12043 (Bcl2)
  09162 Cancer: specific types
   05210 Colorectal cancer
    12043 (Bcl2)
   05226 Gastric cancer
    12043 (Bcl2)
   05215 Prostate cancer
    12043 (Bcl2)
   05222 Small cell lung cancer
    12043 (Bcl2)
  09172 Infectious disease: viral
   05170 Human immunodeficiency virus 1 infection
    12043 (Bcl2)
   05161 Hepatitis B
    12043 (Bcl2)
   05162 Measles
    12043 (Bcl2)
   05169 Epstein-Barr virus infection
    12043 (Bcl2)
  09171 Infectious disease: bacterial
   05152 Tuberculosis
    12043 (Bcl2)
  09174 Infectious disease: parasitic
   05145 Toxoplasmosis
    12043 (Bcl2)
  09164 Neurodegenerative disease
   05014 Amyotrophic lateral sclerosis
    12043 (Bcl2)
   05022 Pathways of neurodegeneration - multiple diseases
    12043 (Bcl2)
  09166 Cardiovascular disease
   05417 Lipid and atherosclerosis
    12043 (Bcl2)
   05418 Fluid shear stress and atherosclerosis
    12043 (Bcl2)
  09167 Endocrine and metabolic disease
   04933 AGE-RAGE signaling pathway in diabetic complications
    12043 (Bcl2)
  09176 Drug resistance: antineoplastic
   01521 EGFR tyrosine kinase inhibitor resistance
    12043 (Bcl2)
   01524 Platinum drug resistance
    12043 (Bcl2)
   01522 Endocrine resistance
    12043 (Bcl2)
 09180 Brite Hierarchies
  09181 Protein families: metabolism
   01009 Protein phosphatases and associated proteins [BR:mmu01009]
    12043 (Bcl2)
Protein phosphatases and associated proteins [BR:mmu01009]
 Protein serine/threonine phosphatases
  Phosphoprotein phosphatases (PPPs)
   Protein phosphatase-1
    PP1-interacting proteins (PIPs)
     12043 (Bcl2)
SSDB
Motif
Pfam: Bcl-2 BH4 Bcl-2_3 ARMH5
Other DBs
NCBI-GeneID: 12043
NCBI-ProteinID: NP_033871
MGI: 88138
Ensembl: ENSMUSG00000057329
UniProt: P10417
Position
1:complement(106465906..106642020)
AA seq 236 aa
MAQAGRTGYDNREIVMKYIHYKLSQRGYEWDAGDADAAPLGAAPTPGIFSFQPESNPMPA
VHRDMAARTSPLRPLVATAGPALSPVPPVVHLTLRRAGDDFSRRYRRDFAEMSSQLHLTP
FTARGRFATVVEELFRDGVNWGRIVAFFEFGGVMCVESVNREMSPLVDNIALWMTEYLNR
HLHTWIQDNGGWDAFVELYGPSMRPLFDFSWLSLKTLLSLALVGACITLGAYLGHK
NT seq 711 nt   +upstreamnt  +downstreamnt
atggcgcaagccgggagaacagggtatgataaccgggagatcgtgatgaagtacatacat
tataagctgtcacagaggggctacgagtgggatgctggagatgcggacgcggcgcccctg
ggggctgcccccacccctggcatcttctccttccagcctgagagcaacccaatgcccgct
gtgcaccgggacatggctgccaggacgtctcctctcaggcccctcgttgccaccgctggg
cctgcgctcagccctgtgccacctgtggtccatctgaccctccgccgggctggggatgac
ttctctcgtcgctaccgtcgtgacttcgcagagatgtccagtcagctgcacctgacgccc
ttcaccgcgaggggacgctttgccacggtggtggaggaactcttcagggatggggtgaac
tgggggaggattgtggccttctttgagttcggtggggtcatgtgtgtggagagcgtcaac
agggagatgtcacccctggtggacaacatcgccctgtggatgactgagtacctgaaccgg
catctgcacacctggatccaggataacggaggctgggatgcctttgtggaactatatggc
cccagcatgcgacctctgtttgatttctcctggctgtctctgaagaccctgctcagcctg
gccctggtcggggcctgcatcactctgggtgcatacctgggccacaagtga

  All links  
Ontology (2)   
   KEGG BRITE (2)   
Pathway (42)   
   KEGG PATHWAY (42)   
Genome (1)   
   KEGG GENOME (1)   
Gene (9)   
   KEGG ORTHOLOGY (1)   
   KEGG GENES (1)   
   RefGene (2)   
   NCBI-PROTEINID (1)   
   NCBI-Gene (1)   
   Ensembl (1)   
   RIKEN BRC-DNA (1)   
   OC (1)   
Protein sequence (4)   
   UniProt (1)   
   SWISS-PROT (1)   
   RefSeq(pep) (2)   
DNA sequence (40)   
   RefSeq(nuc) (2)   
   GenBank (19)   
   EMBL (19)   
Protein domain (4)   
   Pfam (4)   
All databases (102)   

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