KEGG   Mus musculus (house mouse): 13371
Entry
13371             CDS       T01002                                 
Symbol
Dio2, 5DII, DIOII
Name
(RefSeq) deiodinase, iodothyronine, type II
  KO
K17904  type II thyroxine 5'-deiodinase [EC:1.21.99.4]
Organism
mmu  Mus musculus (house mouse)
Pathway
mmu04919  Thyroid hormone signaling pathway
Brite
KEGG Orthology (KO) [BR:mmu00001]
 09150 Organismal Systems
  09152 Endocrine system
   04919 Thyroid hormone signaling pathway
    13371 (Dio2)
Enzymes [BR:mmu01000]
 1. Oxidoreductases
  1.21  Catalysing the reaction X-H + Y-H = X-Y
   1.21.99  With unknown physiological acceptors
    1.21.99.4  thyroxine 5'-deiodinase
     13371 (Dio2)
SSDB
Motif
Pfam: T4_deiodinase AhpC-TSA Redoxin Thioredoxin_8
Other DBs
NCBI-GeneID: 13371
NCBI-ProteinID: NP_034180
MGI: 1338833
Ensembl: ENSMUSG00000007682
UniProt: Q9Z1Y9 Q9QXV5
Position
12:complement(90691326..90705812)
AA seq 262 aa
MGLLSVDLLITLQILPVFFSNCLFLALYDSVILLKHVALLLSRSKSTRGEWRRMLTSEGL
RCVWNSFLLDAYKQVKLGEDAPNSSVVHVSNPESGNNYASEKTADGAECHLLDFASAERP
LVVNFGSATUPPFTRQLPAFRQLVEEFSSVADFLLVYIDEAHPSDGWAVPGDSSLSFEVK
KHRNQEDRCAAAHQLLERFSLPPQCQVVADRMDNNANVAYGVAFERVCIVQRRKIAYLGG
KGPFSYNLQEVRSWLEKNFSKR
NT seq 789 nt   +upstreamnt  +downstreamnt
atgggactcctcagcgtagacttgctgatcaccctgcagatcctgccagtctttttctcc
aactgcctcttcctggcgctctatgactcggtcattctgctcaagcacgtggcgttgctt
ctgagccgctccaagtccactcgcggagagtggaggcgcatgctgacctcagaagggctg
cgctgtgtctggaacagcttcctcctagatgcctacaaacaggttaaactgggtgaagat
gctcccaattccagtgtggtgcacgtctccaatcctgaatcaggtaacaattatgcctcg
gagaagaccgctgatggggccgaatgccaccttcttgactttgccagtgcagagcgccca
ctggtggtcaactttggttcagccacctgaccacctttcactaggcaactgccagccttc
cgccagctggtggaagagttctcctcggtggctgacttcctgttggtatacattgatgag
gctcacccttcggatggctgggcagtgcctggggactcctctctgtcttttgaggttaag
aagcaccggaaccaagaggaccgatgtgcagcagctcaccagctcctggagcgtttctcc
ttgccgccccagtgtcaagttgtggctgaccgcatggacaataatgccaacgtagcttac
ggggtagcctttgaacgtgtgtgcatcgtgcagagacggaaaattgcttacttaggaggg
aagggccccttcagctataacctacaagaagtccgaagttggctggagaagaatttcagc
aagagatga

  All links  
Ontology (2)   
   KEGG BRITE (2)   
Pathway (1)   
   KEGG PATHWAY (1)   
Chemical reaction (1)   
   KEGG ENZYME (1)   
Genome (1)   
   KEGG GENOME (1)   
Gene (8)   
   KEGG ORTHOLOGY (1)   
   KEGG GENES (1)   
   RefGene (2)   
   NCBI-PROTEINID (1)   
   NCBI-Gene (1)   
   Ensembl (1)   
   OC (1)   
Protein sequence (4)   
   UniProt (2)   
   SWISS-PROT (1)   
   RefSeq(pep) (1)   
DNA sequence (37)   
   RefSeq(nuc) (1)   
   GenBank (18)   
   EMBL (18)   
Protein domain (4)   
   Pfam (4)   
All databases (58)   

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