KEGG   Mus musculus (house mouse): 13433
Entry
13433             CDS       T01002                                 
Symbol
Dnmt1, Cxxc9, Dnmt, Dnmt1o, MCMT, MTase, Met-1, Met1, MommeD2, m.MmuI
Name
(RefSeq) DNA methyltransferase 1
  KO
K00558  DNA (cytosine-5)-methyltransferase 1 [EC:2.1.1.37]
Organism
mmu  Mus musculus (house mouse)
Pathway
mmu00270  Cysteine and methionine metabolism
mmu01100  Metabolic pathways
mmu05206  MicroRNAs in cancer
Module
mmu_M00035  Methionine degradation
Brite
KEGG Orthology (KO) [BR:mmu00001]
 09100 Metabolism
  09105 Amino acid metabolism
   00270 Cysteine and methionine metabolism
    13433 (Dnmt1)
 09160 Human Diseases
  09161 Cancer: overview
   05206 MicroRNAs in cancer
    13433 (Dnmt1)
 09180 Brite Hierarchies
  09182 Protein families: genetic information processing
   03000 Transcription factors [BR:mmu03000]
    13433 (Dnmt1)
   03032 DNA replication proteins [BR:mmu03032]
    13433 (Dnmt1)
   03036 Chromosome and associated proteins [BR:mmu03036]
    13433 (Dnmt1)
  09183 Protein families: signaling and cellular processes
   02048 Prokaryotic defense system [BR:mmu02048]
    13433 (Dnmt1)
Enzymes [BR:mmu01000]
 2. Transferases
  2.1  Transferring one-carbon groups
   2.1.1  Methyltransferases
    2.1.1.37  DNA (cytosine-5-)-methyltransferase
     13433 (Dnmt1)
Transcription factors [BR:mmu03000]
 Eukaryotic type
  Zinc finger
   CXXC CpG-binding proteins
    13433 (Dnmt1)
DNA replication proteins [BR:mmu03032]
 Eukaryotic type
  DNA Replication Termination Factors
   DNA methylation enzymes
    13433 (Dnmt1)
Chromosome and associated proteins [BR:mmu03036]
 Eukaryotic type
  Heterochromatin formation proteins
   Other heterochromatin formation proteins
    13433 (Dnmt1)
Prokaryotic defense system [BR:mmu02048]
 Restriction and modification system (R-M system)
  Type II R-M system
   DNA methyltransferases
    13433 (Dnmt1)
SSDB
Motif
Pfam: BAH DNA_methylase DNMT1-RFD DMAP_binding zf-CXXC WHD_RNase_R
Other DBs
NCBI-GeneID: 13433
NCBI-ProteinID: NP_001186360
MGI: 94912
Ensembl: ENSMUSG00000004099
UniProt: P13864 Q3UHZ3
Structure
Position
9:complement(20818501..20871084)
AA seq 1620 aa
MPARTAPARVPALASPAGSLPDHVRRRLKDLERDGLTEKECVREKLNLLHEFLQTEIKSQ
LCDLETKLHKEELSEEGYLAKVKSLLNKDLSLENGTHTLTQKANGCPANGSRPTWRAEMA
DSNRSPRSRPKPRGPRRSKSDSDTLSVETSPSSVATRRTTRQTTITAHFTKGPTKRKPKE
ESEEGNSAESAAEERDQDKKRRVVDTESGAAAAVEKLEEVTAGTQLGPEEPCEQEDDNRS
LRRHTRELSLRRKSKEDPDREARPETHLDEDEDGKKDKRSSRPRSQPRDPAAKRRPKEAE
PEQVAPETPEDRDEDEREEKRRKTTRKKLESHTVPVQSRSERKAAQSKSVIPKINSPKCP
ECGQHLDDPNLKYQQHPEDAVDEPQMLTSEKLSIYDSTSTWFDTYEDSPMHRFTSFSVYC
SRGHLCPVDTGLIEKNVELYFSGCAKAIHDENPSMEGGINGKNLGPINQWWLSGFDGGEK
VLIGFSTAFAEYILMEPSKEYEPIFGLMQEKIYISKIVVEFLQNNPDAVYEDLINKIETT
VPPSTINVNRFTEDSLLRHAQFVVSQVESYDEAKDDDETPIFLSPCMRALIHLAGVSLGQ
RRATRRVMGATKEKDKAPTKATTTKLVYQIFDTFFSEQIEKYDKEDKENAMKRRRCGVCE
VCQQPECGKCKACKDMVKFGGTGRSKQACLKRRCPNLAVKEADDDEEADDDVSEMPSPKK
LHQGKKKKQNKDRISWLGQPMKIEENRTYYQKVSIDEEMLEVGDCVSVIPDDSSKPLYLA
RVTALWEDKNGQMMFHAHWFCAGTDTVLGATSDPLELFLVGECENMQLSYIHSKVKVIYK
APSENWAMEGGTDPETTLPGAEDGKTYFFQLWYNQEYARFESPPKTQPTEDNKHKFCLSC
IRLAELRQKEMPKVLEQIEEVDGRVYCSSITKNGVVYRLGDSVYLPPEAFTFNIKVASPV
KRPKKDPVNETLYPEHYRKYSDYIKGSNLDAPEPYRIGRIKEIHCGKKKGKVNEADIKLR
LYKFYRPENTHRSYNGSYHTDINMLYWSDEEAVVNFSDVQGRCTVEYGEDLLESIQDYSQ
GGPDRFYFLEAYNSKTKNFEDPPNHARSPGNKGKGKGKGKGKGKHQVSEPKEPEAAIKLP
KLRTLDVFSGCGGLSEGFHQAGISETLWAIEMWDPAAQAFRLNNPGTTVFTEDCNVLLKL
VMAGEVTNSLGQRLPQKGDVEMLCGGPPCQGFSGMNRFNSRTYSKFKNSLVVSFLSYCDY
YRPRFFLLENVRNFVSYRRSMVLKLTLRCLVRMGYQCTFGVLQAGQYGVAQTRRRAIILA
AAPGEKLPLFPEPLHVFAPRACQLSVVVDDKKFVSNITRLSSGPFRTITVRDTMSDLPEI
QNGASNSEIPYNGEPLSWFQRQLRGSHYQPILRDHICKDMSPLVAARMRHIPLFPGSDWR
DLPNIQVRLGDGVIAHKLQYTFHDVKNGYSSTGALRGVCSCAEGKACDPESRQFSTLIPW
CLPHTGNRHNHWAGLYGRLEWDGFFSTTVTNPEPMGKQGRVLHPEQHRVVSVRECARSQG
FPDSYRFFGNILDRHRQVGNAVPPPLAKAIGLEIKLCLLSSARESASAAVKAKEEAATKD
NT seq 4863 nt   +upstreamnt  +downstreamnt
atgccagcgcgaacagctccagcccgagtgcctgcgcttgcctccccggcaggctcgctc
ccggaccatgtccgcaggcggctcaaagacttggaaagagatggcttaacagaaaaggag
tgtgtgagggagaaattaaacttactgcatgaattcctgcaaacagaaataaaaagccag
ttgtgtgacttggaaaccaaattacataaagaggaattatctgaggaaggctacctggct
aaagtcaagtccctcttaaataaggatttgtccttggagaacggaacacacactctcact
caaaaagccaacggttgtcccgccaacgggagccggccaacctggagagcagaaatggca
gactcaaatagatccccaagatccaggcccaagcctcggggacccaggagaagcaagtcg
gacagtgacaccctttcagttgaaacttcacctagttccgtggctacgaggagaaccacc
aggcagaccaccatcacggctcacttcacgaagggccccactaaacggaaacccaaggaa
gagtcggaagaggggaactcggctgagtcggctgcagaggagagagaccaggataagaaa
cgcagagttgtagacacagagagtggtgctgcagctgctgtggagaaactggaagaggta
acagcgggaacccagctgggtccggaagagccatgtgaacaggaagatgacaacaggagt
cttcgacgtcacaccagagagctatcattgaggcggaaatcaaaggaggatccagacaga
gaagcaagaccggaaactcacttggacgaggacgaggacggaaaaaaggataaaagaagt
tccagacccaggagccagcccagagatccagctgccaaacggagacccaaggaagcagag
ccagagcaggtagctccagagactcccgaggacagagacgaggatgagagggaggagaag
agacgaaaaacgacacgtaaaaaactggagtcacacaccgttcccgttcagagcagatcg
gagagaaaagccgctcaaagcaaaagtgtgatcccgaagatcaactcaccaaagtgcccc
gagtgtggccagcacctagacgaccctaacctgaagtaccagcagcaccctgaggatgct
gtggatgaaccccagatgttgaccagtgagaaactgtccatctacgactccacctcgacc
tggtttgatacttatgaagattctcccatgcataggttcacttccttcagtgtgtactgc
agtcgcgggcacctgtgtcctgtcgacaccggtctcattgagaagaatgtagagctctac
ttttctgggtgtgccaaagcaattcatgacgagaatccatctatggaaggtggtattaat
ggcaaaaacctcgggccaatcaatcagtggtggctcagtggctttgatggtggcgagaag
gtgctcattggcttctccactgcatttgctgaatacattttgatggagcccagcaaagag
tatgagccaatatttgggctgatgcaggagaaaatttacatcagcaagattgttgttgag
ttcctgcaaaacaatcctgatgctgtatatgaagacctgatcaataagattgagaccact
gttcctccttctaccattaatgtgaaccggttcacagaggactccctcttacgccacgcc
cagtttgtagtgagccaggtagagagttacgacgaagccaaggacgatgatgagaccccc
atcttcttgtctccctgtatgagagccctgatccatttggctggtgtctccctgggacag
aggcgagcaacaaggcgcgtcatgggtgctaccaaggagaaggacaaagcacccacgaaa
gccaccaccaccaagctggtctatcagatctttgacactttcttctcagagcagattgag
aagtatgataaggaggacaaggagaatgccatgaagcgccgccgctgtggtgtctgtgag
gtctgtcagcagcctgagtgtgggaagtgcaaggcgtgcaaagatatggtgaagtttggt
ggcactggacggagtaagcaggcttgcctcaagaggaggtgtcctaacttggcggtgaag
gaggcagacgacgatgaagaggctgatgatgatgtgtcagagatgccatcacccaaaaag
ctgcatcaggggaagaagaagaagcagaacaaggaccgcatctcctggcttgggcagcct
atgaagattgaagagaatagaacttactatcagaaggtgagcatcgatgaggagatgcta
gaggtgggcgactgcgtctcggtcattccagatgattcctccaaaccactctatctagcc
agggtcacagctctgtgggaagacaaaaatggtcagatgatgttccatgcgcactggttc
tgcgctgggacagacacagtcctgggagccacctccgaccccctggaactgttcctggtg
ggcgagtgcgaaaacatgcagctttcctacatccacagcaaggtcaaggtcatctacaaa
gccccttctgaaaactgggccatggagggaggcacagaccctgagaccacactgcctggg
gctgaggatggcaagacttacttcttccagctctggtacaaccaggagtacgcaaggttt
gaatccccacccaagacccagccgaccgaggacaacaagcacaagttctgcctatcttgt
atccggctggctgagctgagacaaaaagaaatgcccaaggtcctggaacaaattgaggag
gtggatggccgggtctactgcagttccatcaccaagaatggtgttgtctaccgactgggt
gacagtgtgtaccttcctcccgaggcctttactttcaacatcaaagtggctagccccgtg
aaacgcccaaagaaggatcctgtgaacgagaccctgtaccctgagcactaccgcaagtat
tctgactacatcaaggggagcaacctggatgctccagagccctatcgcatcggtcggata
aaagagatccactgtggcaagaagaaaggcaaggtcaacgaggcagacatcaagctgagg
ctctacaagttctacaggcctgagaatacccacaggtcctacaacggatcctatcacact
gacatcaacatgctttactggagcgacgaggaagctgtggtgaacttcagcgacgtgcag
ggccgctgtaccgtggagtacggggaagacctacttgagagcatccaggattattcacaa
gggggccctgaccgcttctacttcctcgaggcctacaattcaaagaccaagaactttgaa
gacccaccaaaccatgcccgcagccctgggaacaaagggaaagggaaggggaaagggaag
gggaaggggaagcatcaggtgtcagagcccaaagagcctgaggcagccatcaaactgccc
aagctccggaccctggatgtgttttccggctgtggagggttatcggaaggattccaccaa
gcaggcatctcggaaacgctgtgggccatcgagatgtgggacccggcagcccaggcattt
cggctgaacaaccccggcaccacagtgttcacagaggactgcaacgtgcttcttaagctg
gtcatggctggggaggtgaccaactctctgggccaaaggctgccacagaagggcgatgtg
gagatgctgtgtggtgggccaccctgccagggcttcagtggcatgaaccgcttcaactcc
cgcacttactccaagttcaaaaactccctagtggtctccttcctcagctactgtgactac
taccggcctcggttcttccttctggagaacgtcaggaacttcgtgtcctacagacgctcc
atggtgctgaagctcacactgcgctgcctggtccgcatgggctaccagtgcacctttggt
gtgctccaggctggacagtatggcgtggcccagacacgaaggagggccatcatcttggct
gcagccccaggagaaaagctgcctctgttcccagagcctctgcatgtgtttgcgccccgt
gcctgccagctgagcgttgtggtggatgacaagaagtttgttagcaacataacgaggctg
agctcggggcccttccgaaccatcaccgtgcgagacaccatgtctgacctccccgagatc
cagaatggagcctcgaattctgagatcccctacaatggagagccactgtcctggttccag
aggcagctgcgaggatcacactaccagcccatcctcagggaccatatctgcaaggacatg
agcccactggtggctgcccgcatgcggcacatcccactgttcccaggatcagattggcgt
gacctgcccaacatacaggtgcggctgggagatggcgtcatagcccataagctacagtac
acctttcatgatgtgaaaaatggctacagcagcaccggtgccctgcgtggagtctgttcc
tgtgcagaaggcaaggcctgcgaccctgagtccaggcaattcagcaccctcatcccctgg
tgcctgccgcacactgggaaccggcacaaccactgggctggcctctacgggcgtctggag
tgggatggcttcttcagcaccactgtcaccaaccctgagcccatgggcaagcagggtcgg
gtgctccacccggagcagcaccgggtcgtgagtgttcgggaatgtgcccgctcccagggc
tttccagatagctaccggttcttcggcaacatcctggacagacaccggcaggtgggtaat
gctgtgccaccacccctggccaaagccattggcctggagattaagctctgcctgctgtcc
agtgctcgggagagcgcatcagctgcagttaaagcaaaagaggaggctgctaccaaggac
tag

  All links  
Gene (66)   
   RefGene (58)   
   NCBI-PROTEINID (1)   
   NCBI-Gene (1)   
   Ensembl (1)   
   RIKEN BRC-DNA (4)   
   OC (1)   
Protein sequence (10)   
   UniProt (2)   
   SWISS-PROT (1)   
   RefSeq(pep) (7)   
DNA sequence (45)   
   RefSeq(nuc) (7)   
   GenBank (19)   
   EMBL (19)   
3D Structure (11)   
   PDB (11)   
Protein domain (6)   
   Pfam (6)   
All databases (138)   

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