KEGG   Mus musculus (house mouse): 13435
Entry
13435             CDS       T01002                                 
Symbol
Dnmt3a, MmuIIIA
Name
(RefSeq) DNA methyltransferase 3A
  KO
K17398  DNA (cytosine-5)-methyltransferase 3A [EC:2.1.1.37]
Organism
mmu  Mus musculus (house mouse)
Pathway
mmu00270  Cysteine and methionine metabolism
mmu01100  Metabolic pathways
mmu04148  Efferocytosis
mmu05206  MicroRNAs in cancer
Module
mmu_M00035  Methionine degradation
Brite
KEGG Orthology (KO) [BR:mmu00001]
 09100 Metabolism
  09105 Amino acid metabolism
   00270 Cysteine and methionine metabolism
    13435 (Dnmt3a)
 09140 Cellular Processes
  09141 Transport and catabolism
   04148 Efferocytosis
    13435 (Dnmt3a)
 09160 Human Diseases
  09161 Cancer: overview
   05206 MicroRNAs in cancer
    13435 (Dnmt3a)
 09180 Brite Hierarchies
  09182 Protein families: genetic information processing
   03000 Transcription factors [BR:mmu03000]
    13435 (Dnmt3a)
   03032 DNA replication proteins [BR:mmu03032]
    13435 (Dnmt3a)
   03036 Chromosome and associated proteins [BR:mmu03036]
    13435 (Dnmt3a)
Enzymes [BR:mmu01000]
 2. Transferases
  2.1  Transferring one-carbon groups
   2.1.1  Methyltransferases
    2.1.1.37  DNA (cytosine-5-)-methyltransferase
     13435 (Dnmt3a)
Transcription factors [BR:mmu03000]
 Eukaryotic type
  Zinc finger
   Cys4 GATA-factors
    13435 (Dnmt3a)
DNA replication proteins [BR:mmu03032]
 Eukaryotic type
  DNA Replication Termination Factors
   DNA methylation enzymes
    13435 (Dnmt3a)
Chromosome and associated proteins [BR:mmu03036]
 Eukaryotic type
  Heterochromatin formation proteins
   Other heterochromatin formation proteins
    13435 (Dnmt3a)
SSDB
Motif
Pfam: DNM3A_N ADD_DNMT3 DNMT3_ADD_GATA1-like DNA_methylase PWWP
Other DBs
NCBI-GeneID: 13435
NCBI-ProteinID: NP_001258682
MGI: 1261827
Ensembl: ENSMUSG00000020661
UniProt: O88508
Structure
Position
12:3851559..3964442
AA seq 908 aa
MPSSGPGDTSSSSLEREDDRKEGEEQEENRGKEERQEPSATARKVGRPGRKRKHPPVESS
DTPKDPAVTTKSQPMAQDSGPSDLLPNGDLEKRSEPQPEEGSPAAGQKGGAPAEGEGTET
PPEASRAVENGCCVTKEGRGASAGEGKEQKQTNIESMKMEGSRGRLRGGLGWESSLRQRP
MPRLTFQAGDPYYISKRKRDEWLARWKREAEKKAKVIAVMNAVEENQASGESQKVEEASP
PAVQQPTDPASPTVATTPEPVGGDAGDKNATKAADDEPEYEDGRGFGIGELVWGKLRGFS
WWPGRIVSWWMTGRSRAAEGTRWVMWFGDGKFSVVCVEKLMPLSSFCSAFHQATYNKQPM
YRKAIYEVLQVASSRAGKLFPACHDSDESDSGKAVEVQNKQMIEWALGGFQPSGPKGLEP
PEEEKNPYKEVYTDMWVEPEAAAYAPPPPAKKPRKSTTEKPKVKEIIDERTRERLVYEVR
QKCRNIEDICISCGSLNVTLEHPLFIGGMCQNCKNCFLECAYQYDDDGYQSYCTICCGGR
EVLMCGNNNCCRCFCVECVDLLVGPGAAQAAIKEDPWNCYMCGHKGTYGLLRRREDWPSR
LQMFFANNHDQEFDPPKVYPPVPAEKRKPIRVLSLFDGIATGLLVLKDLGIQVDRYIASE
VCEDSITVGMVRHQGKIMYVGDVRSVTQKHIQEWGPFDLVIGGSPCNDLSIVNPARKGLY
EGTGRLFFEFYRLLHDARPKEGDDRPFFWLFENVVAMGVSDKRDISRFLESNPVMIDAKE
VSAAHRARYFWGNLPGMNRPLASTVNDKLELQECLEHGRIAKFSKVRTITTRSNSIKQGK
DQHFPVFMNEKEDILWCTEMERVFGFPVHYTDVSNMSRLARQRLLGRSWSVPVIRHLFAP
LKEYFACV
NT seq 2727 nt   +upstreamnt  +downstreamnt
atgccctccagcggccccggggacaccagcagctcctctctggagcgggaggatgatcga
aaggaaggagaggaacaggaggagaaccgtggcaaggaagagcgccaggagcccagcgcc
acggcccggaaggtggggaggcctggccggaagcgcaagcacccaccggtggaaagcagt
gacacccccaaggacccagcagtgaccaccaagtctcagcccatggcccaggactctggc
ccctcagatctgctacccaatggagacttggagaagcggagtgaaccccaacctgaggag
gggagcccagctgcagggcagaagggtggggccccagctgaaggagagggaactgagacc
ccaccagaagcctccagagctgtggagaatggctgctgtgtgaccaaggaaggccgtgga
gcctctgcaggagagggcaaagaacagaagcagaccaacatcgaatccatgaaaatggag
ggctcccggggccgactgcgaggtggcttgggctgggagtccagcctccgtcagcgaccc
atgccaagactcaccttccaggcaggggacccctactacatcagcaaacggaaacgggat
gagtggctggcacgttggaaaagggaggctgagaagaaagccaaggtaattgcagtaatg
aatgctgtggaagagaaccaggcctctggagagtctcagaaggtggaggaggccagccct
cctgctgtgcagcagcccacggaccctgcttctccgactgtggccaccacccctgagcca
gtaggaggggatgctggggacaagaatgctaccaaagcagccgacgatgagcctgagtat
gaggatggccggggctttggcattggagagctggtgtgggggaaacttcggggcttctcc
tggtggccaggccgaattgtgtcttggtggatgacaggccggagccgagcagctgaaggc
actcgctgggtcatgtggttcggagatggcaagttctcagtggtgtgtgtggagaagctc
atgccgctgagctccttctgcagtgcattccaccaggccacctacaacaagcagcccatg
taccgcaaagccatctacgaagtcctccaggtggccagcagccgtgccgggaagctgttt
ccagcttgccatgacagtgatgaaagtgacagtggcaaggctgtggaagtgcagaacaag
cagatgattgaatgggccctcggtggcttccagccctcgggtcctaagggcctggagcca
ccagaagaagagaagaatccttacaaggaagtttacaccgacatgtgggtggagcctgaa
gcagctgcttacgccccacccccaccagccaagaaacccagaaagagcacaacagagaaa
cctaaggtcaaggagatcattgatgagcgcacaagggagcggctggtgtatgaggtgcgc
cagaagtgcagaaacatcgaggacatttgtatctcatgtgggagcctcaatgtcaccctg
gagcacccactcttcattggaggcatgtgccagaactgtaagaactgcttcttggagtgt
gcttaccagtatgacgacgatgggtaccagtcctattgcaccatctgctgtggggggcgt
gaagtgctcatgtgtgggaacaacaactgctgcaggtgcttttgtgtcgagtgtgtggat
ctcttggtggggccaggagctgctcaggcagccattaaggaagacccctggaactgctac
atgtgcgggcataagggcacctatgggctgctgcgaagacgggaagactggccttctcga
ctccagatgttctttgccaataaccatgaccaggaatttgaccccccaaaggtttaccca
cctgtgccagctgagaagaggaagcccatccgcgtgctgtctctctttgatgggattgct
acagggctcctggtgctgaaggacctgggcatccaagtggaccgctacattgcctccgag
gtgtgtgaggactccatcacggtgggcatggtgcggcaccagggaaagatcatgtacgtc
ggggacgtccgcagcgtcacacagaagcatatccaggagtggggcccattcgacctggtg
attggaggcagtccctgcaatgacctctccattgtcaaccctgcccgcaagggactttat
gagggtactggccgcctcttctttgagttctaccgcctcctgcatgatgcgcggcccaag
gagggagatgatcgccccttcttctggctctttgagaatgtggtggccatgggcgttagt
gacaagagggacatctcgcgatttcttgagtctaaccccgtgatgattgacgccaaagaa
gtgtctgctgcacacagggcccgttacttctggggtaaccttcctggcatgaacaggcct
ttggcatccactgtgaatgataagctggagctgcaagagtgtctggagcacggcagaata
gccaagttcagcaaagtgaggaccattaccaccaggtcaaactctataaagcagggcaaa
gaccagcatttccccgtcttcatgaacgagaaggaggacatcctgtggtgcactgaaatg
gaaagggtgtttggcttccccgtccactacacagacgtctccaacatgagccgcttggcg
aggcagagactgctgggccgatcgtggagcgtgccggtcatccgccacctcttcgctccg
ctgaaggaatattttgcttgtgtgtaa

  All links  
Gene (18)   
   RefGene (11)   
   NCBI-PROTEINID (1)   
   NCBI-Gene (1)   
   Ensembl (1)   
   RIKEN BRC-DNA (3)   
   OC (1)   
Protein sequence (10)   
   UniProt (1)   
   SWISS-PROT (1)   
   RefSeq(pep) (8)   
DNA sequence (56)   
   RefSeq(nuc) (8)   
   GenBank (24)   
   EMBL (24)   
3D Structure (2)   
   PDB (2)   
Protein domain (5)   
   Pfam (5)   
All databases (91)   

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