KEGG   Mus musculus (house mouse): 13436
Entry
13436             CDS       T01002                                 
Symbol
Dnmt3b, MmuIIIB
Name
(RefSeq) DNA (cytosine-5)-methyltransferase 3B isoform 1
  KO
K17399  DNA (cytosine-5)-methyltransferase 3B [EC:2.1.1.37]
Organism
mmu  Mus musculus (house mouse)
Pathway
mmu00270  Cysteine and methionine metabolism
mmu01100  Metabolic pathways
mmu05206  MicroRNAs in cancer
Module
mmu_M00035  Methionine degradation
Brite
KEGG Orthology (KO) [BR:mmu00001]
 09100 Metabolism
  09105 Amino acid metabolism
   00270 Cysteine and methionine metabolism
    13436 (Dnmt3b)
 09160 Human Diseases
  09161 Cancer: overview
   05206 MicroRNAs in cancer
    13436 (Dnmt3b)
 09180 Brite Hierarchies
  09182 Protein families: genetic information processing
   03000 Transcription factors [BR:mmu03000]
    13436 (Dnmt3b)
   03032 DNA replication proteins [BR:mmu03032]
    13436 (Dnmt3b)
   03036 Chromosome and associated proteins [BR:mmu03036]
    13436 (Dnmt3b)
Enzymes [BR:mmu01000]
 2. Transferases
  2.1  Transferring one-carbon groups
   2.1.1  Methyltransferases
    2.1.1.37  DNA (cytosine-5-)-methyltransferase
     13436 (Dnmt3b)
Transcription factors [BR:mmu03000]
 Eukaryotic type
  Zinc finger
   Cys4 GATA-factors
    13436 (Dnmt3b)
DNA replication proteins [BR:mmu03032]
 Eukaryotic type
  DNA Replication Termination Factors
   DNA methylation enzymes
    13436 (Dnmt3b)
Chromosome and associated proteins [BR:mmu03036]
 Eukaryotic type
  Heterochromatin formation proteins
   Other heterochromatin formation proteins
    13436 (Dnmt3b)
SSDB
Motif
Pfam: ADD_DNMT3 DNMT3_ADD_GATA1-like DNA_methylase PWWP
Other DBs
NCBI-GeneID: 13436
NCBI-ProteinID: NP_001003961
MGI: 1261819
Ensembl: ENSMUSG00000027478
UniProt: O88509 Q3KR45
Structure
Position
2:153491332..153529650
AA seq 859 aa
MKGDSRHLNEEEGASGYEECIIVNGNFSDQSSDTKDAPSPPVLEAICTEPVCTPETRGRR
SSSRLSKREVSSLLNYTQDMTGDGDRDDEVDDGNGSDILMPKLTRETKDTRTRSESPAVR
TRHSNGTSSLERQRASPRITRGRQGRHHVQEYPVEFPATRSRRRRASSSASTPWSSPASV
DFMEEVTPKSVSTPSVDLSQDGDQEGMDTTQVDAESRDGDSTEYQDDKEFGIGDLVWGKI
KGFSWWPAMVVSWKATSKRQAMPGMRWVQWFGDGKFSEISADKLVALGLFSQHFNLATFN
KLVSYRKAMYHTLEKARVRAGKTFSSSPGESLEDQLKPMLEWAHGGFKPTGIEGLKPNKK
QPVVNKSKVRRSDSRNLEPRRRENKSRRRTTNDSAASESPPPKRLKTNSYGGKDRGEDEE
SRERMASEVTNNKGNLEDRCLSCGKKNPVSFHPLFEGGLCQSCRDRFLELFYMYDEDGYQ
SYCTVCCEGRELLLCSNTSCCRCFCVECLEVLVGAGTAEDAKLQEPWSCYMCLPQRCHGV
LRRRKDWNMRLQDFFTTDPDLEEFEPPKLYPAIPAAKRRPIRVLSLFDGIATGYLVLKEL
GIKVEKYIASEVCAESIAVGTVKHEGQIKYVNDVRKITKKNIEEWGPFDLVIGGSPCNDL
SNVNPARKGLYEGTGRLFFEFYHLLNYTRPKEGDNRPFFWMFENVVAMKVNDKKDISRFL
ACNPVMIDAIKVSAAHRARYFWGNLPGMNRPVMASKNDKLELQDCLEFSRTAKLKKVQTI
TTKSNSIRQGKNQLFPVVMNGKDDVLWCTELERIFGFPAHYTDVSNMGRGARQKLLGRSW
SVPVIRHLFAPLKDYFACE
NT seq 2580 nt   +upstreamnt  +downstreamnt
atgaagggagacagcagacatctgaatgaagaagagggtgccagcgggtatgaggagtgc
attatcgttaatgggaacttcagtgaccagtcctcagacacgaaggatgctccctcaccc
ccagtcttggaggcaatctgcacagagccagtctgcacaccagagaccagaggccgcagg
tcaagctcccggctgtctaagagggaggtctccagccttctgaattacacgcaggacatg
acaggagatggagacagagatgatgaagtagatgatgggaatggctctgatattctaatg
ccaaagctcacccgtgagaccaaggacaccaggacgcgctctgaaagcccggctgtccga
acccgacatagcaatgggacctccagcttggagaggcaaagagcctcccccagaatcacc
cgaggtcggcagggccgccaccatgtgcaggagtaccctgtggagtttccggctaccagg
tctcggagacgtcgagcatcatcttcagcaagcacgccatggtcatcccctgccagcgtc
gacttcatggaagaagtgacacctaagagcgtcagtaccccatcagttgacttgagccag
gatggagatcaggagggtatggataccacacaggtggatgcagagagcagagatggagac
agcacagagtatcaggatgataaagagtttggaataggtgacctcgtgtggggaaagatc
aagggcttctcctggtggcctgccatggtggtgtcctggaaagccacctccaagcgacag
gccatgcccggaatgcgctgggtacagtggtttggtgatggcaagttttctgagatctct
gctgacaaactggtggctctggggctgttcagccagcactttaatctggctaccttcaat
aagctggtttcttataggaaggccatgtaccacactctggagaaagccagggttcgagct
ggcaagaccttctccagcagtcctggagagtcactggaggaccagctgaagcccatgctg
gagtgggcccacggtggcttcaagcctactgggatcgagggcctcaaacccaacaagaag
caaccagtggttaataagtcgaaggtgcgtcgttcagacagtaggaacttagaacccagg
agacgcgagaacaaaagtcgaagacgcacaaccaatgactctgctgcttctgagtccccc
ccacccaagcgcctcaagacaaatagctatggcgggaaggaccgaggggaggatgaggag
agccgagaacggatggcttctgaagtcaccaacaacaagggcaatctggaagaccgctgt
ttgtcctgtggaaagaagaaccctgtgtccttccaccccctctttgagggtgggctctgt
cagagttgccgggatcgcttcctagagctcttctacatgtatgatgaggacggctatcag
tcctactgcaccgtgtgctgtgagggccgtgaactgctgctgtgcagtaacacaagctgc
tgcagatgcttctgtgtggagtgtctggaggtgctggtgggcgcaggcacagctgaggat
gccaagctgcaggaaccctggagctgctatatgtgcctccctcagcgctgccatggggtc
ctccgacgcaggaaagattggaacatgcgcctgcaagacttcttcactactgatcctgac
ctggaagaatttgagccacccaagttgtacccagcaattcctgcagccaaaaggaggccc
attagagtcctgtctctgtttgatggaattgcaacggggtacttggtgctcaaggagttg
ggtattaaagtggaaaagtacattgcctccgaagtctgtgcagagtccatcgctgtggga
actgttaagcatgaaggccagatcaaatatgtcaatgacgtccggaaaatcaccaagaaa
aatattgaagagtggggcccgttcgacttggtgattggtggaagcccatgcaatgatctc
tctaacgtcaatcctgcccgcaaaggtttatatgagggcacaggaaggctcttcttcgag
ttttaccacttgctgaattatacccgccccaaggagggcgacaaccgtccattcttctgg
atgttcgagaatgttgtggccatgaaagtgaatgacaagaaagacatctcaagattcctg
gcatgtaacccagtgatgatcgatgccatcaaggtgtctgctgctcacagggcccggtac
ttctggggtaacctacccggaatgaacaggcccgtgatggcttcaaagaatgataagctc
gagctgcaggactgcctggagttcagtaggacagcaaagttaaagaaagtgcagacaata
accaccaagtcgaactccatcagacagggcaaaaaccagcttttccctgtagtcatgaat
ggcaaggacgacgttttgtggtgcactgagctcgaaaggatcttcggcttccctgctcac
tacacggacgtgtccaacatgggccgcggcgcccgtcagaagctgctgggcaggtcctgg
agtgtaccggtcatcagacacctgtttgcccccttgaaggactactttgcctgtgaatag

  All links  
Gene (30)   
   RefGene (24)   
   NCBI-PROTEINID (1)   
   NCBI-Gene (1)   
   Ensembl (1)   
   RIKEN BRC-DNA (2)   
   OC (1)   
Protein sequence (26)   
   UniProt (2)   
   SWISS-PROT (1)   
   RefSeq(pep) (23)   
DNA sequence (58)   
   RefSeq(nuc) (24)   
   GenBank (17)   
   EMBL (17)   
3D Structure (1)   
   PDB (1)   
Protein domain (4)   
   Pfam (4)   
All databases (119)   

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