KEGG   Mus musculus (house mouse): 14245
Entry
14245             CDS       T01002                                 
Symbol
Lpin1, Lipin1, fld
Name
(RefSeq) lipin 1
  KO
K15728  phosphatidate phosphatase LPIN [EC:3.1.3.4]
Organism
mmu  Mus musculus (house mouse)
Pathway
mmu00561  Glycerolipid metabolism
mmu00564  Glycerophospholipid metabolism
mmu01100  Metabolic pathways
mmu04150  mTOR signaling pathway
mmu04936  Alcoholic liver disease
Module
mmu_M00089  Triacylglycerol biosynthesis
Brite
KEGG Orthology (KO) [BR:mmu00001]
 09100 Metabolism
  09103 Lipid metabolism
   00561 Glycerolipid metabolism
    14245 (Lpin1)
   00564 Glycerophospholipid metabolism
    14245 (Lpin1)
 09130 Environmental Information Processing
  09132 Signal transduction
   04150 mTOR signaling pathway
    14245 (Lpin1)
 09160 Human Diseases
  09167 Endocrine and metabolic disease
   04936 Alcoholic liver disease
    14245 (Lpin1)
 09180 Brite Hierarchies
  09181 Protein families: metabolism
   01009 Protein phosphatases and associated proteins [BR:mmu01009]
    14245 (Lpin1)
Enzymes [BR:mmu01000]
 3. Hydrolases
  3.1  Acting on ester bonds
   3.1.3  Phosphoric-monoester hydrolases
    3.1.3.4  phosphatidate phosphatase
     14245 (Lpin1)
Protein phosphatases and associated proteins [BR:mmu01009]
 HAD phosphatases
  Other HAD phosphatases
   14245 (Lpin1)
SSDB
Motif
Pfam: LNS2 Lipin_N Lipin_mid APP1_cat WRNPLPNID
Other DBs
NCBI-GeneID: 14245
NCBI-ProteinID: NP_056578
MGI: 1891340
Ensembl: ENSMUSG00000020593
UniProt: Q91ZP3 E9QKQ5
Structure
Position
12:complement(16585670..16697020)
AA seq 924 aa
MNYVGQLAGQVFVTVKELYKGLNPATLSGCIDIIVIRQPNGSLQCSPFHVRFGKMGVLRS
REKVVDIEINGESVDLHMKLGDNGEAFFVQETDNDQEIIPMYLATSPILSEGAARMESQL
KRNSVDRIRCLDPTTAAQGLPPSDTPSTGSLGKKRRKRRRKAQLDNLKRDDNVNTSEDED
MFPIEMSSDEDTAPMDGSRTLPNDVPPFQDDIPKENFPSISTYPQSASYPSSDREWSPSP
SSLVDCQRTPPHLAEGVLSSSCPLQSCHFHASESPSGSRPSTPKSDSELVSKSADRLTPK
NNLEMLWLWGELPQAAKSSSPHKMKESSPLGSRKTPDKMNFQAIHSESSDTFSDQSPTMA
RGLLIHQSKAQTEMQFVNEEDLESLGAAAPPSPVAEELKAPYPNTAQSSSKTDSPSRKKD
KRSRHLGADGVYLDDLTDMDPEVAALYFPKNGDPGGLPKQASDNGARSANQSPQSVGGSG
IDSGVESTSDSLRDLPSIAISLCGGLSDHREITKDAFLEQAVSYQQFADNPAIIDDPNLV
VKVGNKYYNWTTAAPLLLAMQAFQKPLPKATVESIMRDKMPKKGGRWWFSWRGRNATIKE
ESKPEQCLTGKGHNTGEQPAQLGLATRIKHESSSSDEEHAAAKPSGSSHLSLLSNVSYKK
TLRLTSEQLKSLKLKNGPNDVVFSVTTQYQGTCRCEGTIYLWNWDDKVIISDIDGTITRS
DTLGHILPTLGKDWTHQGIAKLYHKVSQNGYKFLYCSARAIGMADMTRGYLHWVNERGTV
LPQGPLLLSPSSLFSALHREVIEKKPEKFKVQCLTDIKNLFFPNTEPFYAAFGNRPADVY
SYKQVGVSLNRIFTVNPKGELVQEHAKTNISSYVRLCEVVDHVFPLLKRSHSCDFPCSDT
FSNFTFWREPLPPFENQDMHSASA
NT seq 2775 nt   +upstreamnt  +downstreamnt
atgaattacgtggggcagctggccggccaggtgtttgtgacggtgaaggagctctacaag
ggactgaaccccgccacgctgtcgggatgcatcgacatcattgtcatccggcagcccaat
ggcagtctgcagtgctcccctttccacgtccgcttcggcaagatgggtgtcctccgctcc
cgagagaaagtggtggacatagaaatcaatggggagtccgtggatttgcacatgaagttg
ggagacaacggagaagcattttttgttcaagagactgacaacgatcaggaaatcatcccc
atgtacctggccacgtcccccatcctgtcagaaggagctgcgagaatggaaagccagctg
aagaggaactctgtagacagaatcaggtgcctggatcccactacagctgcccagggcctg
cctcccagcgacaccccatccactggttctctggggaagaagagaaggaaaaggaggagg
aaggcccagttggacaatctcaaaagagatgacaatgtcaacacatctgaggatgaggac
atgtttcccatagagatgagctcggatgaggacacagcaccgatggatggaagcagaact
cttcctaatgatgtaccaccattccaagatgatattcctaaggaaaacttcccctcgatt
tcaacgtacccccagtcagcatcgtatcccagttcggacagagaatggtcccccagcccc
agcagcctggtagattgccagaggactccccctcacctggccgagggagttctctctagc
tcttgtcctctgcagtcttgccacttccatgcttcggaaagtccttcaggctcccggccc
tcaacaccaaaaagtgactctgagctggtcagtaagtctgcagacaggttgacgccaaag
aataacctggaaatgctctggctgtggggtgaattgccacaggctgcaaagtcctcttct
ccacacaagatgaaagagtccagccccttagggagccggaagactcctgataaaatgaat
tttcaggccattcacagcgagtcttcagatacttttagtgaccagtcgccaacaatggcc
cggggactgctcatccaccagagtaaggcccagacggaaatgcagtttgtgaacgaggag
gatctcgagtccttgggggcggcagccccaccttcacccgtggccgaagagctcaaggcc
ccatatcccaacaccgcacagtcgtcgagcaagacagattccccttccaggaagaaagat
aaacggagccgacaccttggagctgatggtgtttatctggacgacctcacggacatggac
cctgaagtggcagccctgtatttccccaagaatggggatcctggtgggctccccaaacaa
gccagtgacaacggagccaggtcagccaaccagtcaccacagtctgtgggaggctcgggc
atcgacagtggtgtggagagcacctccgacagcctgagggacctgccatccatcgccatc
tccctctgcggtggcctcagtgaccacagagagatcaccaaagatgcatttttggaacaa
gccgtgtcatatcagcaatttgccgacaaccctgctatcatcgatgaccccaacctcgtg
gtcaaggttggcaataagtattacaactggacaacagcagctcctctacttctggcgatg
caggctttccagaaacctttgccaaaggccactgtggaatccatcatgagagataagatg
cccaaaaagggaggaagatggtggttttcctggagaggaagaaatgccacaatcaaagag
gaaagcaagcctgaacagtgcctgactgggaaaggccacaataccggagagcagcctgcc
cagcttggcctggccaccaggataaagcatgagtcatcctccagtgatgaagagcacgca
gccgccaagccatcaggttcgagccacctctctctcttgtccaacgtcagctacaaaaag
accctgcggctcacgtcggagcagctgaaaagcttgaagttgaagaacggccccaatgat
gtggtgttcagtgtcactacccagtaccagggcacctgtcgctgcgagggcaccatctac
ctgtggaattgggacgacaaagtcatcatctcagatatcgatgggaccatcacaagatct
gatactcttggtcacattttgcccacgctgggaaaggattggactcaccagggcattgca
aagctgtaccacaaagtaagccagaatggctacaagtttctctattgttcggcacgtgcc
attgggatggcggacatgacgaggggctacctgcactgggtcaacgagaggggcacggtg
cttccacagggcccgcttctgctcagcccgagcagcctcttctccgccttgcacagagaa
gtgattgaaaagaagccagaaaagttcaaagtccagtgtttgacagacatcaagaacctg
tttttcccaaacacagaacccttctatgctgcttttgggaaccggcctgctgatgtgtat
tcctacaagcaagtgggagtgtccctgaataggatcttcactgtgaaccccaagggtgag
ctggtgcaggagcatgccaagaccaacatcagctcgtacgtgcggctctgcgaagtggtc
gatcacgtcttcccattgctaaagagaagccattcctgtgacttcccctgttcagacact
ttcagtaacttcaccttttggagagagccactgccaccttttgaaaaccaggacatgcat
tcagcctcagcttga

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