Entry |
|
Gene name |
Fos, D12Rfj, D12Rfj1, c-f, c-fos, cF, cFos
|
Definition |
(RefSeq) FBJ osteosarcoma oncogene
|
KO |
K04379 | proto-oncogene protein c-fos |
|
Organism |
|
Pathway |
mmu04620 | Toll-like receptor signaling pathway |
mmu04658 | Th1 and Th2 cell differentiation |
mmu04660 | T cell receptor signaling pathway |
mmu04662 | B cell receptor signaling pathway |
mmu04928 | Parathyroid hormone synthesis, secretion and action |
mmu04932 | Non-alcoholic fatty liver disease |
mmu04935 | Growth hormone synthesis, secretion and action |
mmu05166 | Human T-cell leukemia virus 1 infection |
mmu05167 | Kaposi sarcoma-associated herpesvirus infection |
mmu05170 | Human immunodeficiency virus 1 infection |
mmu05235 | PD-L1 expression and PD-1 checkpoint pathway in cancer |
mmu05418 | Fluid shear stress and atherosclerosis |
|
Brite |
KEGG Orthology (KO) [BR:mmu00001]
09130 Environmental Information Processing
09132 Signal transduction
04010 MAPK signaling pathway
14281 (Fos)
04668 TNF signaling pathway
14281 (Fos)
04024 cAMP signaling pathway
14281 (Fos)
09140 Cellular Processes
09143 Cell growth and death
04210 Apoptosis
14281 (Fos)
09150 Organismal Systems
09151 Immune system
04620 Toll-like receptor signaling pathway
14281 (Fos)
04660 T cell receptor signaling pathway
14281 (Fos)
04658 Th1 and Th2 cell differentiation
14281 (Fos)
04659 Th17 cell differentiation
14281 (Fos)
04657 IL-17 signaling pathway
14281 (Fos)
04662 B cell receptor signaling pathway
14281 (Fos)
09152 Endocrine system
04915 Estrogen signaling pathway
14281 (Fos)
04917 Prolactin signaling pathway
14281 (Fos)
04921 Oxytocin signaling pathway
14281 (Fos)
04926 Relaxin signaling pathway
14281 (Fos)
04935 Growth hormone synthesis, secretion and action
14281 (Fos)
04928 Parathyroid hormone synthesis, secretion and action
14281 (Fos)
09156 Nervous system
04725 Cholinergic synapse
14281 (Fos)
04728 Dopaminergic synapse
14281 (Fos)
09158 Development and regeneration
04380 Osteoclast differentiation
14281 (Fos)
09159 Environmental adaptation
04713 Circadian entrainment
14281 (Fos)
09160 Human Diseases
09161 Cancer: overview
05200 Pathways in cancer
14281 (Fos)
05231 Choline metabolism in cancer
14281 (Fos)
05235 PD-L1 expression and PD-1 checkpoint pathway in cancer
14281 (Fos)
09162 Cancer: specific types
05210 Colorectal cancer
14281 (Fos)
05224 Breast cancer
14281 (Fos)
09172 Infectious disease: viral
05166 Human T-cell leukemia virus 1 infection
14281 (Fos)
05170 Human immunodeficiency virus 1 infection
14281 (Fos)
05161 Hepatitis B
14281 (Fos)
05171 Coronavirus disease - COVID-19
14281 (Fos)
05162 Measles
14281 (Fos)
05167 Kaposi sarcoma-associated herpesvirus infection
14281 (Fos)
09171 Infectious disease: bacterial
05132 Salmonella infection
14281 (Fos)
05135 Yersinia infection
14281 (Fos)
05133 Pertussis
14281 (Fos)
09174 Infectious disease: parasitic
05140 Leishmaniasis
14281 (Fos)
05142 Chagas disease
14281 (Fos)
09163 Immune disease
05323 Rheumatoid arthritis
14281 (Fos)
09165 Substance dependence
05031 Amphetamine addiction
14281 (Fos)
09166 Cardiovascular disease
05417 Lipid and atherosclerosis
14281 (Fos)
05418 Fluid shear stress and atherosclerosis
14281 (Fos)
09167 Endocrine and metabolic disease
04932 Non-alcoholic fatty liver disease
14281 (Fos)
09176 Drug resistance: antineoplastic
01522 Endocrine resistance
14281 (Fos)
09180 Brite Hierarchies
09182 Protein families: genetic information processing
03000 Transcription factors [BR:mmu03000]
14281 (Fos)
04131 Membrane trafficking [BR:mmu04131]
14281 (Fos)
Transcription factors [BR:mmu03000]
Eukaryotic type
Basic leucine zipper (bZIP)
AP-1(-like) components, Fos
14281 (Fos)
Membrane trafficking [BR:mmu04131]
Autophagy
Chaperone mediated autophagy (CMA)
Selective cargos
14281 (Fos)
|
SSDB |
|
Motif |
|
Other DBs |
|
Structure |
PDB: |
Position |
12 D2; 12 39.7 cM
|
AA seq |
380 aa
MMFSGFNADYEASSSRCSSASPAGDSLSYYHSPADSFSSMGSPVNTQDFCADLSVSSANF
IPTVTAISTSPDLQWLVQPTLVSSVAPSQTRAPHPYGLPTQSAGAYARAGMVKTVSGGRA
QSIGRRGKVEQLSPEEEEKRRIRRERNKMAAAKCRNRRRELTDTLQAETDQLEDEKSALQ
TEIANLLKEKEKLEFILAAHRPACKIPDDLGFPEEMSVASLDLTGGLPEASTPESEEAFT
LPLLNDPEPKPSLEPVKSISNVELKAEPFDDFLFPASSRPSGSETSRSVPDVDLSGSFYA
ADWEPLHSNSLGMGPMVTELEPLCTPVVTCTPGCTTYTSSFVFTYPEADSFPSCAAAHRK
GSSSNEPSSDSLSSPTLLAL |
NT seq |
1143 nt +upstreamnt +downstreamnt
atgatgttctcgggtttcaacgccgactacgaggcgtcatcctcccgctgcagtagcgcc
tccccggccggggacagcctttcctactaccattccccagccgactccttctccagcatg
ggctctcctgtcaacacacaggacttttgcgcagatctgtccgtctctagtgccaacttt
atccccacggtgacagccatctccaccagcccagacctgcagtggctggtgcagcccact
ctggtctcctccgtggccccatcgcagaccagagcgccccatccttacggactccccacc
cagtctgctggggcttacgccagagcgggaatggtgaagaccgtgtcaggaggcagagcg
cagagcatcggcagaaggggcaaagtagagcagctatctcctgaagaggaagagaaacgg
agaatccgaagggaacggaataagatggctgcagccaagtgccggaatcggaggagggag
ctgacagatacactccaagcggagacagatcaacttgaagatgagaagtctgcgttgcag
actgagattgccaatctgctgaaagagaaggaaaaactggagtttattttggcagcccac
cgacctgcctgcaagatccccgatgaccttggcttcccagaggagatgtctgtggcctcc
ctggatttgactggaggtctgcctgaggcttccaccccagagtctgaggaggccttcacc
ctgccccttctcaacgaccctgagcccaagccatccttggagccagtcaagagcatcagc
aacgtggagctgaaggcagaaccctttgatgacttcttgtttccggcatcatctaggccc
agtggctcagagacctcccgctctgtgccagatgtggacctgtccggttccttctatgca
gcagactgggagcctctgcacagcaattccttggggatggggcccatggtcacagagctg
gagcccctgtgtactcccgtggtcacctgtactccgggctgcactacttacacgtcttcc
tttgtcttcacctaccctgaagctgactccttcccaagctgtgccgctgcccaccgaaag
ggcagcagcagcaacgagccctcctccgactccctgagctcacccacgctgctggccctg
tga |