KEGG   Mus musculus (house mouse): 14370
Entry
14370             CDS       T01002                                 
Symbol
Fzd8, Fz8
Name
(RefSeq) frizzled class receptor 8
  KO
K02375  frizzled 5/8
Organism
mmu  Mus musculus (house mouse)
Pathway
mmu04150  mTOR signaling pathway
mmu04310  Wnt signaling pathway
mmu04390  Hippo signaling pathway
mmu04550  Signaling pathways regulating pluripotency of stem cells
mmu04916  Melanogenesis
mmu04934  Cushing syndrome
mmu05010  Alzheimer disease
mmu05022  Pathways of neurodegeneration - multiple diseases
mmu05165  Human papillomavirus infection
mmu05200  Pathways in cancer
mmu05205  Proteoglycans in cancer
mmu05217  Basal cell carcinoma
mmu05224  Breast cancer
mmu05225  Hepatocellular carcinoma
mmu05226  Gastric cancer
Brite
KEGG Orthology (KO) [BR:mmu00001]
 09130 Environmental Information Processing
  09132 Signal transduction
   04310 Wnt signaling pathway
    14370 (Fzd8)
   04390 Hippo signaling pathway
    14370 (Fzd8)
   04150 mTOR signaling pathway
    14370 (Fzd8)
 09140 Cellular Processes
  09144 Cellular community - eukaryotes
   04550 Signaling pathways regulating pluripotency of stem cells
    14370 (Fzd8)
 09160 Human Diseases
  09161 Cancer: overview
   05200 Pathways in cancer
    14370 (Fzd8)
   05205 Proteoglycans in cancer
    14370 (Fzd8)
  09162 Cancer: specific types
   05225 Hepatocellular carcinoma
    14370 (Fzd8)
   05226 Gastric cancer
    14370 (Fzd8)
   05217 Basal cell carcinoma
    14370 (Fzd8)
   05224 Breast cancer
    14370 (Fzd8)
  09172 Infectious disease: viral
   05165 Human papillomavirus infection
    14370 (Fzd8)
  09164 Neurodegenerative disease
   05010 Alzheimer disease
    14370 (Fzd8)
   05022 Pathways of neurodegeneration - multiple diseases
    14370 (Fzd8)
  09167 Endocrine and metabolic disease
   04934 Cushing syndrome
    14370 (Fzd8)
 09180 Brite Hierarchies
  09183 Protein families: signaling and cellular processes
   04030 G protein-coupled receptors [BR:mmu04030]
    14370 (Fzd8)
G protein-coupled receptors [BR:mmu04030]
 Frizzled / Smoothened family
  14370 (Fzd8)
SSDB
Motif
Pfam: Frizzled Fz
Other DBs
NCBI-GeneID: 14370
NCBI-ProteinID: NP_032084
MGI: 108460
Ensembl: ENSMUSG00000036904
UniProt: Q61091
Structure
Position
18:9212856..9216201
AA seq 685 aa
MEWGYLLEVTSLLAALAVLQRSSGAAAASAKELACQEITVPLCKGIGYNYTYMPNQFNHD
TQDEAGLEVHQFWPLVEIQCSPDLKFFLCSMYTPICLEDYKKPLPPCRSVCERAKAGCAP
LMRQYGFAWPDRMRCDRLPEQGNPDTLCMDYNRTDLTTAAPSPPRRLPPPPPPGEQPPSG
SGHSRPPGARPPHRGGSSRGSGDAAAAPPSRGGKARPPGGGAAPCEPGCQCRAPMVSVSS
ERHPLYNRVKTGQIANCALPCHNPFFSQDERAFTVFWIGLWSVLCFVSTFATVSTFLIDM
ERFKYPERPIIFLSACYLFVSVGYLVRLVAGHEKVACSGGAPGAGGAGGAGGAAAAGAGA
AGAGASSPGARGEYEELGAVEQHVRYETTGPALCTVVFLLVYFFGMASSIWWVILSLTWF
LAAGMKWGNEAIAGYSQYFHLAAWLVPSVKSIAVLALSSVDGDPVAGICYVGNQSLDNLR
GFVLAPLVIYLFIGTMFLLAGFVSLFRIRSVIKQQGGPTKTHKLEKLMIRLGLFTVLYTV
PAAVVVACLFYEQHNRPRWEATHNCPCLRDLQPDQARRPDYAVFMLKYFMCLVVGITSGV
WVWSGKTLESWRALCTRCCWASKGAAVGAGAGGSGPGGSGPGPGGGGGHGGGGGSLYSDV
STGLTWRSGTASSVSYPKQMPLSQV
NT seq 2058 nt   +upstreamnt  +downstreamnt
atggagtggggttacctgttggaagtgacctcgctcctagccgccttggcggtgctacag
cgctctagcggcgctgccgcggcttcggccaaggagctggcgtgccaagagatcacggtg
ccgttgtgcaaaggcatcggttacaactacacttacatgcccaaccagttcaaccacgac
acgcaagatgaggcgggcctagaggtgcaccagttttggccgctggtggagatacagtgc
tccccggacctcaagttctttctgtgtagcatgtacacgcccatctgcctggaggactac
aagaagcctctgccgccttgtcgctctgtgtgtgaacgcgccaaggccggctgcgcgccg
ctcatgcgccagtacggctttgcttggcctgaccgcatgcgctgcgatcggttgccggag
cagggcaacccggacactctgtgcatggactacaaccgcaccgacctcaccacggccgcg
cccagcccaccgcgccgcctgcctccgccgcctcctcccggcgagcagccgccctctggc
agcggccacagccgcccgccaggggccaggcccccacatcgtggcggcagcagtaggggc
agcggggacgcggcggctgcgcccccttcgcgcggcgggaaggcgaggccccctggtggc
ggcgctgctccctgcgagccggggtgccagtgccgcgcgcccatggtgagcgtgtccagc
gaacgccacccgctctacaaccgcgtcaagaccggccagatcgccaactgtgcgctgccc
tgccacaaccccttctttagccaggatgagcgcgccttcaccgtcttctggatcggcctg
tggtcggtgctctgcttcgtctccaccttcgccactgtctctaccttcctcatcgatatg
gagcgctttaagtacccggaacggcccatcatattcctctccgcctgttacctcttcgtg
tctgtcgggtacctggtgcgcctggtggcaggacatgagaaagtggcctgcagcggcggc
gctccgggtgctggcggagctgggggtgcgggcggcgcggcggcggctggcgcaggggca
gcgggagcgggggcgagcagcccgggcgcgcgcggcgagtacgaggagctgggtgcagtc
gagcagcatgttcgctatgaaaccactggccccgcgctgtgcacggtggtctttctcctt
gtctacttttttggcatggccagctccatctggtgggtaatcctgtcgctcacgtggttc
ttggcagctggcatgaagtggggtaatgaggccatagcaggctactcgcagtacttccac
ctggccgcgtggcttgtgcccagcgtcaagtccatcgcggtgctggcgctcagctccgta
gacggcgacccggtggcgggcatctgctacgtgggcaaccagagccttgacaacctacgc
ggctttgtgctggcgccactggttatctacctcttcattgggactatgtttctgttagct
ggcttcgtgtcgctgttccgaatccgttcagtcatcaagcagcaaggaggcccaactaag
acacacaagctagaaaaactcatgatccgcttgggcctcttcaccgtgctctacacggtg
cccgctgccgtcgttgtcgcctgccttttctatgagcagcacaaccgaccgcgctgggag
gccacgcacaactgcccatgccttcgggacctgcaaccggaccaggctcgcaggcccgat
tacgcggtcttcatgctcaagtacttcatgtgcctagtagtgggcatcacatcgggcgtg
tgggtctggtccggcaagactctggagtcctggcgcgcgttgtgcactaggtgctgctgg
gccagcaagggcgctgcagtaggcgcgggcgctggaggcagcggccctgggggcagtgga
cccgggcccggcggaggtgggggacacggcggaggcgggggatccctctacagcgacgtc
agtaccggcctgacgtggcggtctggcacggccagctctgtatcttaccctaagcaaatg
ccattgtcccaggtctga

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