KEGG   Mus musculus (house mouse): 14677
Entry
14677             CDS       T01002                                 
Symbol
Gnai1, Gialpha1, Gnai-1, Hg1b
Name
(RefSeq) G protein subunit alpha i1
  KO
K04630  guanine nucleotide-binding protein G(i) subunit alpha
Organism
mmu  Mus musculus (house mouse)
Pathway
mmu04015  Rap1 signaling pathway
mmu04022  cGMP-PKG signaling pathway
mmu04024  cAMP signaling pathway
mmu04062  Chemokine signaling pathway
mmu04071  Sphingolipid signaling pathway
mmu04261  Adrenergic signaling in cardiomyocytes
mmu04360  Axon guidance
mmu04371  Apelin signaling pathway
mmu04540  Gap junction
mmu04611  Platelet activation
mmu04670  Leukocyte transendothelial migration
mmu04713  Circadian entrainment
mmu04723  Retrograde endocannabinoid signaling
mmu04724  Glutamatergic synapse
mmu04725  Cholinergic synapse
mmu04726  Serotonergic synapse
mmu04727  GABAergic synapse
mmu04728  Dopaminergic synapse
mmu04730  Long-term depression
mmu04914  Progesterone-mediated oocyte maturation
mmu04915  Estrogen signaling pathway
mmu04916  Melanogenesis
mmu04921  Oxytocin signaling pathway
mmu04923  Regulation of lipolysis in adipocytes
mmu04924  Renin secretion
mmu04926  Relaxin signaling pathway
mmu04928  Parathyroid hormone synthesis, secretion and action
mmu04934  Cushing syndrome
mmu04935  Growth hormone synthesis, secretion and action
mmu04971  Gastric acid secretion
mmu05012  Parkinson disease
mmu05030  Cocaine addiction
mmu05032  Morphine addiction
mmu05034  Alcoholism
mmu05133  Pertussis
mmu05142  Chagas disease
mmu05145  Toxoplasmosis
mmu05163  Human cytomegalovirus infection
mmu05170  Human immunodeficiency virus 1 infection
mmu05200  Pathways in cancer
mmu05207  Chemical carcinogenesis - receptor activation
Brite
KEGG Orthology (KO) [BR:mmu00001]
 09130 Environmental Information Processing
  09132 Signal transduction
   04015 Rap1 signaling pathway
    14677 (Gnai1)
   04371 Apelin signaling pathway
    14677 (Gnai1)
   04071 Sphingolipid signaling pathway
    14677 (Gnai1)
   04024 cAMP signaling pathway
    14677 (Gnai1)
   04022 cGMP-PKG signaling pathway
    14677 (Gnai1)
 09140 Cellular Processes
  09144 Cellular community - eukaryotes
   04540 Gap junction
    14677 (Gnai1)
 09150 Organismal Systems
  09151 Immune system
   04611 Platelet activation
    14677 (Gnai1)
   04670 Leukocyte transendothelial migration
    14677 (Gnai1)
   04062 Chemokine signaling pathway
    14677 (Gnai1)
  09152 Endocrine system
   04923 Regulation of lipolysis in adipocytes
    14677 (Gnai1)
   04915 Estrogen signaling pathway
    14677 (Gnai1)
   04914 Progesterone-mediated oocyte maturation
    14677 (Gnai1)
   04921 Oxytocin signaling pathway
    14677 (Gnai1)
   04926 Relaxin signaling pathway
    14677 (Gnai1)
   04935 Growth hormone synthesis, secretion and action
    14677 (Gnai1)
   04928 Parathyroid hormone synthesis, secretion and action
    14677 (Gnai1)
   04916 Melanogenesis
    14677 (Gnai1)
   04924 Renin secretion
    14677 (Gnai1)
  09153 Circulatory system
   04261 Adrenergic signaling in cardiomyocytes
    14677 (Gnai1)
  09154 Digestive system
   04971 Gastric acid secretion
    14677 (Gnai1)
  09156 Nervous system
   04724 Glutamatergic synapse
    14677 (Gnai1)
   04727 GABAergic synapse
    14677 (Gnai1)
   04725 Cholinergic synapse
    14677 (Gnai1)
   04728 Dopaminergic synapse
    14677 (Gnai1)
   04726 Serotonergic synapse
    14677 (Gnai1)
   04730 Long-term depression
    14677 (Gnai1)
   04723 Retrograde endocannabinoid signaling
    14677 (Gnai1)
  09158 Development and regeneration
   04360 Axon guidance
    14677 (Gnai1)
  09159 Environmental adaptation
   04713 Circadian entrainment
    14677 (Gnai1)
 09160 Human Diseases
  09161 Cancer: overview
   05200 Pathways in cancer
    14677 (Gnai1)
   05207 Chemical carcinogenesis - receptor activation
    14677 (Gnai1)
  09172 Infectious disease: viral
   05170 Human immunodeficiency virus 1 infection
    14677 (Gnai1)
   05163 Human cytomegalovirus infection
    14677 (Gnai1)
  09171 Infectious disease: bacterial
   05133 Pertussis
    14677 (Gnai1)
  09174 Infectious disease: parasitic
   05145 Toxoplasmosis
    14677 (Gnai1)
   05142 Chagas disease
    14677 (Gnai1)
  09164 Neurodegenerative disease
   05012 Parkinson disease
    14677 (Gnai1)
  09165 Substance dependence
   05030 Cocaine addiction
    14677 (Gnai1)
   05032 Morphine addiction
    14677 (Gnai1)
   05034 Alcoholism
    14677 (Gnai1)
  09167 Endocrine and metabolic disease
   04934 Cushing syndrome
    14677 (Gnai1)
 09180 Brite Hierarchies
  09183 Protein families: signaling and cellular processes
   04147 Exosome [BR:mmu04147]
    14677 (Gnai1)
   04031 GTP-binding proteins [BR:mmu04031]
    14677 (Gnai1)
Exosome [BR:mmu04147]
 Exosomal proteins
  Proteins found in most exosomes
   14677 (Gnai1)
GTP-binding proteins [BR:mmu04031]
 Heterotrimeric G-proteins
  Alpha Subunits
   Alpha type 1 (Gi/o) [OT]
    14677 (Gnai1)
SSDB
Motif
Pfam: G-alpha Arf Gtr1_RagA TniB AAA_29 FtsK_SpoIIIE
Other DBs
NCBI-GeneID: 14677
NCBI-ProteinID: NP_034435
MGI: 95771
Ensembl: ENSMUSG00000057614
UniProt: B2RSH2
Structure
Position
5:complement(18470133..18565411)
AA seq 354 aa
MGCTLSAEDKAAVERSKMIDRNLREDGEKAAREVKLLLLGAGESGKSTIVKQMKIIHEAG
YSEEECKQYKAVVYSNTIQSIIAIIRAMGRLKIDFGDSARADDARQLFVLAGAAEEGFMT
AELAGVIKRLWKDSGVQACFNRSREYQLNDSAAYYLNDLDRIAQPNYIPTQQDVLRTRVK
TTGIVETHFTFKDLHFKMFDVGGQRSERKKWIHCFEGVTAIIFCVALSDYDLVLAEDEEM
NRMHESMKLFDSICNNKWFTDTSIILFLNKKDLFEEKIKKSPLTICYPEYAGSNTYEEAA
AYIQCQFEDLNKRKDTKEIYTHFTCATDTKNVQFVFDAVTDVIIKNNLKDCGLF
NT seq 1065 nt   +upstreamnt  +downstreamnt
atgggctgcacattgagcgctgaggacaaggcggccgtggagcgcagcaagatgatcgac
cgcaacctccgggaggacggcgagaaggcggcgcgggaggtcaagctgctgctgctgggt
gctggggaatctggaaagagtaccattgtgaagcagatgaagattatccacgaagccggc
tactcggaagaggagtgtaagcagtacaaggcagtggtctacagcaacactatccagtcc
atcattgccatcattagagccatggggaggttgaaaatcgacttcggagactctgctcgg
gcggatgatgctcgccaacttttcgtgcttgctggggctgcagaagaaggctttatgact
gcagagctcgccggtgtcataaagagactgtggaaagacagtggtgtgcaagcctgcttc
aacagatcccgggagtaccagctgaacgattcggcagcgtactatctgaatgacttggac
agaatagcacagccaaattacatcccaactcagcaggatgtcctcagaaccagagtgaag
accacagggattgtggaaacccactttaccttcaaagatcttcattttaaaatgtttgac
gtgggaggtcagaggtcagagcggaagaagtggatccactgctttgaaggggtgaccgcc
atcatcttctgtgtggccctgagtgactatgacctggttcttgctgaagatgaagaaatg
aaccgtatgcacgagagcatgaagctgttcgatagcatctgtaacaacaagtggtttaca
gacacgtccatcatccttttcctcaacaagaaggacctcttcgaagaaaaaataaaaaag
agccccctcacgatatgctacccagaatatgcaggctcaaacacatatgaagaagcggcc
gcgtatattcagtgtcagtttgaagacctcaataaaaggaaggacacaaaggaaatttac
acccacttcacgtgcgccacagatacgaagaacgtgcagttcgtgttcgatgctgtaaca
gacgtcatcataaagaataacctaaaagactgtggtctcttctaa

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