KEGG   Mus musculus (mouse): 14813
Entry
14813             CDS       T01002                                 

Gene name
Grin2c, GluN2C, NMDAR2C, NR2C
Definition
(RefSeq) glutamate receptor, ionotropic, NMDA2C (epsilon 3)
  KO
K05211  glutamate receptor ionotropic, NMDA 2C
Organism
mmu  Mus musculus (mouse)
Pathway
mmu04020  Calcium signaling pathway
mmu04024  cAMP signaling pathway
mmu04080  Neuroactive ligand-receptor interaction
mmu04713  Circadian entrainment
mmu04720  Long-term potentiation
mmu04724  Glutamatergic synapse
mmu05010  Alzheimer disease
mmu05014  Amyotrophic lateral sclerosis
mmu05017  Spinocerebellar ataxia
mmu05020  Prion disease
mmu05030  Cocaine addiction
mmu05031  Amphetamine addiction
mmu05033  Nicotine addiction
mmu05034  Alcoholism
Brite
KEGG Orthology (KO) [BR:mmu00001]
 09130 Environmental Information Processing
  09132 Signal transduction
   04020 Calcium signaling pathway
    14813 (Grin2c)
   04024 cAMP signaling pathway
    14813 (Grin2c)
  09133 Signaling molecules and interaction
   04080 Neuroactive ligand-receptor interaction
    14813 (Grin2c)
 09150 Organismal Systems
  09156 Nervous system
   04724 Glutamatergic synapse
    14813 (Grin2c)
   04720 Long-term potentiation
    14813 (Grin2c)
  09159 Environmental adaptation
   04713 Circadian entrainment
    14813 (Grin2c)
 09160 Human Diseases
  09164 Neurodegenerative disease
   05010 Alzheimer disease
    14813 (Grin2c)
   05014 Amyotrophic lateral sclerosis
    14813 (Grin2c)
   05017 Spinocerebellar ataxia
    14813 (Grin2c)
   05020 Prion disease
    14813 (Grin2c)
  09165 Substance dependence
   05030 Cocaine addiction
    14813 (Grin2c)
   05031 Amphetamine addiction
    14813 (Grin2c)
   05033 Nicotine addiction
    14813 (Grin2c)
   05034 Alcoholism
    14813 (Grin2c)
 09180 Brite Hierarchies
  09183 Protein families: signaling and cellular processes
   04040 Ion channels [BR:mmu04040]
    14813 (Grin2c)
Ion channels [BR:mmu04040]
 Ligand-gated channels
  Glutamate (ionotropic)
   14813 (Grin2c)
SSDB
Motif
Pfam: Lig_chan Lig_chan-Glu_bd SBP_bac_3 ANF_receptor NMDAR2_C
Other DBs
NCBI-GeneID: 14813
NCBI-ProteinID: NP_034480
MGI: 95822
Ensembl: ENSMUSG00000020734
Vega: OTTMUSG00000003665
UniProt: Q01098 A2A6S2
Position
11 E2; 11 80.8 cM
AA seq 1239 aa
MGGALGPALLLTSLLGAWAGLGAGQGEQAVTVAVVFGSSGPLQAQARTRLTPQNFLDLPL
EIQPLTIGVNNTNPSSILTQICGLLGAARVHGIVFEDNVDTEAVAQLLDFVSSQTHVPIL
SISGGSAVVLTPKEPGSAFLQLGVSLEQQLQVLFKVLEEYDWSAFAVITSLHPGHALFLE
GVRAVADASYLSWRLLDVLTLELGPGGPRARTQRLLRQVDAPVLVAYCSREEAEVLFAEA
AQAGLVGPGHVWLVPNLALGSTDAPPAAFPVGLISVVTESWRLSLRQKVRDGVAILALGA
HSYRRQYGTLPAPAGDCRSHPGPVSPAREAFYRHLLNVTWEGRDFSFSPGGYLVQPTMVV
IALNRHRLWEMVGRWDHGVLYMKYPVWPRYSTSLQPVVDSRHLTVATLEERPFVIVESPD
PGTGGCVPNTVPCRRQSNHTFSSGDITPYTKLCCKGFCIDILKKLAKVVKFSYDLYLVTN
GKHGKRVRGVWNGMIGEVYYKRADMAIGSLTINEERSEIIDFSVPFVETGISVMVARSNG
TVSPSAFLEPYSPAVWVMMFVMCLTVVAITVFMFEYFSPVSYNQNLTKGKKSGGPSFTIG
KSVWLLWALVFNNSVPIENPRGTTSKIMVLVWAFFAVIFLASYTANLAAFMIQEQYIDTV
SGLSDKKFQRPQDQYPPFRFGTVPNGSTERNIRSNYRDMHTHMVKFNQRSVEDALTSLKM
GKLDAFIYDAAVLNYMAGKDEGCKLVTIGSGKVFATTGYGIAMQKDSHWKRAIDLALLQF
LGDGETQKLETVWLSGICHNEKNEVMSSKLDIDNMAGVFYMLLVAMGLALLVFAWEHLVY
WKLRHSVPSSSQLDFLLAFSRGIYSCFNGVQSLPSPARPPSPDLTAGSAQANVLKMLQAA
RDMVSTADVSGSLDRATRTIENWGNNRRAPAPTTSGPRSCTPGPPGQPSPSGWRPPGGGR
TPLARRAPQPPARPATCAGSPQPDVSRASCRHAWDARWPVRVGHQGSHLSASERRALPER
SLLHAHCHYSSFPRAERSGRPFLPLFPEPPEPDDLPLLGPEQLARREALLRAAWARGPRP
RHASLPSSVAEAFTRSNPLPARCTGHACACPCPQSRPSCRHVAQTQSLRLPSYREACVEG
VPAGVAATWQPRQHVCLHTHTHLPFCWGTVCRHPPPCSSHSPWLIGTWEPPSHRGRTLGL
GTGYRDSGVLEEVSREACGTQGFPRSCTWRRISSLESEV
NT seq 3720 nt   +upstreamnt  +downstreamnt
atgggtggagccctggggcccgccctgcttctcacttcactccttggtgcttgggcaggg
ctgggcgcagggcagggagaacaggccgtgaccgtggcggtggtgtttggcagctctggg
ccactgcaggcccaggcccggactcgtctcaccccgcagaacttcctggacttgcctctg
gagatccagccactcaccatcggggtcaacaataccaaccccagcagcatcctcacccaa
atctgtgggctcctgggtgccgcccgagtccacggcatcgtctttgaggacaacgtggac
actgaggccgtggctcagctgctggatttcgtctcctctcagacccacgtgcccatcctc
agcatcagtggaggttctgctgtggtcctcacccccaaggagccaggctccgcctttcta
cagctgggcgtgtccctggagcagcagctgcaggtgctgttcaaggtgctggaggaatac
gactggagcgcgttcgctgtcatcaccagcctgcacccgggccacgcgctcttcctcgag
ggcgtgcgcgccgtcgccgacgccagctacctgagctggcggctgctggacgtgctcacg
ctggagctgggccccggtgggccgcgagcgcgcactcagcgcttactgcgccaggtcgac
gccccggtgctggtggcctactgctcccgtgaagaggcggaggtgctcttcgcggaggct
gcacaggctggcttggtgggacccggtcacgtgtggttagtacctaatctggcgctggga
agcaccgacgctccccctgcagccttcccagtgggcctcatcagtgtggtcaccgagagt
tggcgccttagcctacgccagaaagtccgcgacggtgtagccattctggccctcggtgcc
cacagctaccgacgccagtacggtacccttccagccccggctggagactgccgaagccac
ccaggacccgtcagccctgccagggaggctttctacaggcatctgctgaatgtcacctgg
gaaggccgagacttctcttttagccctggtgggtacctggtccagcccacaatggttgtg
atcgctctcaaccggcatcgcctctgggagatggtgggacggtgggatcatggggtcctg
tacatgaagtatccagtatggcctcgctacagcacttctctgcagcctgtggtggacagc
cggcacctgacagtggccacactggaagaaaggccttttgtcattgtggagagccctgac
cctggcacaggtggctgtgttcccaacactgtgccctgccgtagacagagcaaccacacc
ttcagcagcggggatataaccccctacaccaagctctgttgtaagggcttctgcatcgac
atcctcaagaagctggccaaggtggtcaagttctcctacgacttgtacctggtgaccaac
ggcaagcacggcaagagggttcgtggtgtgtggaatggtatgatcggtgaggtatactac
aagcgggcagacatggccatcggctccctcaccatcaatgaagagcgctcagagattata
gacttctctgtgccttttgtggagaccggcatcagtgtgatggtggcaaggagcaacggc
accgtctccccctcggcttttctggagccctacagccctgccgtgtgggtgatgatgttt
gtaatgtgcctcacggtggttgccatcactgtcttcatgttcgagtatttcagccctgtc
agctacaaccagaatctcaccaagggcaagaagtcaggtggaccatccttcaccattggc
aagtccgtgtggttgctgtgggcactggtcttcaacaactctgttcccatcgagaacccc
cggggcaccaccagcaagatcatggtcctggtgtgggccttcttcgctgtcatcttcctc
gctagctacacggccaatctggcagccttcatgatccaggaacaatacatcgacactgtg
tcgggccttagtgacaagaagtttcagcggcctcaagaccaatacccacccttccgtttt
ggcacggtacctaatggcagcacagagaggaacattcgtagcaactatcgtgacatgcac
actcacatggtcaagttcaaccagcgctcggtggaggatgctctcacaagcctgaagatg
gggaagctggacgccttcatctatgatgccgccgtcctcaactacatggcgggcaaggac
gaaggctgcaagctggtcaccattgggtctggcaaagtctttgccaccactggctatggc
attgccatgcagaaagactcccactggaagcgggccatagacctggcgctcctgcagttc
ctgggggatggggagacacagaagttggagacagtgtggctctcagggatctgccataac
gagaagaacgaggtgatgagcagcaagctggacattgacaacatggcgggcgtcttctac
atgctgttggtggccatggggctggcccttctggtctttgcctgggagcacctggtctac
tggaaacttcgacactcagtgcccagctcatcccagctggacttcctgctggctttcagc
aggggcatctacagctgcttcaacggggtacagagccttccgagccctgcgcggccgccc
agcccggaccttacagcaggctcagcccaggccaatgtgctgaagatgctgcaggcggct
cgagacatggtgagcacagcggacgtgagcggctctttggaccgcgccactcgtaccatc
gagaactggggcaacaatcgccgcgcgcctgctcccaccacctccggcccgcggtcatgc
accccgggtcctccgggacaaccgagtcccagcggctggcggcctcccggtgggggccgc
accccgctagcgcgccgggccccgcagcctcccgctcgccccgcgacctgcgcagggtcg
cctcagcccgacgtgtcccgagcatcctgcaggcacgcttgggatgcgcggtggccagtg
cgagtcgggcatcagggatcgcacctctcggcctccgagcggcgcgcgctcccggagcgc
tccctgttgcacgcgcactgccactacagttccttccctcgagcagagaggtcagggcgc
ccatttctcccgctattcccggagcccccggagcccgacgacctgccgctgctcgggccg
gaacagctggctcggcgggaggctctgctgcgcgcggcctgggccaggggcccgcgccct
cggcacgcttccctgcccagctccgtggcagaagccttcactcgatccaaccctctgcct
gccaggtgtaccggtcacgcctgcgcttgcccatgtccccaaagccggccatcctgccgg
cacgtggctcaaacacagtcgttgcggctgccatcctaccgggaggcctgtgtggagggc
gtgccagcaggggtggccgccacctggcagcccagacagcatgtctgcctgcacacccat
acccacctgccgttctgctgggggactgtctgccgtcaccctccaccctgttccagccac
agtccctggctcattggaacttgggagcctccatcacacagaggcaggaccctggggcta
ggtacaggctacagggacagtggggtgctagaagaggtcagcagggaagcttgtgggaca
caagggtttccaaggtcctgcacctggaggcggatctccagcctggaatcagaagtgtga

DBGET integrated database retrieval system