Entry |
|
Symbol |
Hspa5, Bip, D2Wsu141e, D2Wsu17e, Grp78, Hsce70, SEZ-7, Sez7, baffled, mBiP
|
Name |
(RefSeq) heat shock protein 5
|
KO |
|
Organism |
mmu Mus musculus (house mouse)
|
Pathway |
mmu04141 | Protein processing in endoplasmic reticulum |
mmu04612 | Antigen processing and presentation |
mmu05022 | Pathways of neurodegeneration - multiple diseases |
|
Brite |
KEGG Orthology (KO) [BR:mmu00001]
09120 Genetic Information Processing
09123 Folding, sorting and degradation
03060 Protein export
14828 (Hspa5)
04141 Protein processing in endoplasmic reticulum
14828 (Hspa5)
09150 Organismal Systems
09151 Immune system
04612 Antigen processing and presentation
14828 (Hspa5)
09152 Endocrine system
04918 Thyroid hormone synthesis
14828 (Hspa5)
09160 Human Diseases
09164 Neurodegenerative disease
05012 Parkinson disease
14828 (Hspa5)
05014 Amyotrophic lateral sclerosis
14828 (Hspa5)
05020 Prion disease
14828 (Hspa5)
05022 Pathways of neurodegeneration - multiple diseases
14828 (Hspa5)
09166 Cardiovascular disease
05417 Lipid and atherosclerosis
14828 (Hspa5)
09180 Brite Hierarchies
09182 Protein families: genetic information processing
03110 Chaperones and folding catalysts [BR:mmu03110]
14828 (Hspa5)
04131 Membrane trafficking [BR:mmu04131]
14828 (Hspa5)
09183 Protein families: signaling and cellular processes
04147 Exosome [BR:mmu04147]
14828 (Hspa5)
Enzymes [BR:mmu01000]
3. Hydrolases
3.6 Acting on acid anhydrides
3.6.4 Acting on acid anhydrides to facilitate cellular and subcellular movement
3.6.4.10 non-chaperonin molecular chaperone ATPase
14828 (Hspa5)
Chaperones and folding catalysts [BR:mmu03110]
Heat shock proteins
HSP70 / DNAK
14828 (Hspa5)
Membrane trafficking [BR:mmu04131]
Endoplasmic reticulum (ER) - Golgi transport
Forward pathways
ER-Golgi intermediate compartment (ERGIC) proteins
14828 (Hspa5)
Exosome [BR:mmu04147]
Exosomal proteins
Exosomal proteins of haemopoietic cells (B-cell, T-cell, DC-cell, reticulocyte, and mast cell)
14828 (Hspa5)
Exosomal proteins of other body fluids (saliva and urine)
14828 (Hspa5)
Exosomal proteins of colorectal cancer cells
14828 (Hspa5)
|
SSDB |
|
Motif |
|
Other DBs |
|
Position |
2:34662102..34666541
|
AA seq |
655 aa
MMKFTVVAAALLLLGAVRAEEEDKKEDVGTVVGIDLGTTYSCVGVFKNGRVEIIANDQGN
RITPSYVAFTPEGERLIGDAAKNQLTSNPENTVFDAKRLIGRTWNDPSVQQDIKFLPFKV
VEKKTKPYIQVDIGGGQTKTFAPEEISAMVLTKMKETAEAYLGKKVTHAVVTVPAYFNDA
QRQATKDAGTIAGLNVMRIINEPTAAAIAYGLDKREGEKNILVFDLGGGTFDVSLLTIDN
GVFEVVATNGDTHLGGEDFDQRVMEHFIKLYKKKTGKDVRKDNRAVQKLRREVEKAKRAL
SSQHQARIEIESFFEGEDFSETLTRAKFEELNMDLFRSTMKPVQKVLEDSDLKKSDIDEI
VLVGGSTRIPKIQQLVKEFFNGKEPSRGINPDEAVAYGAAVQAGVLSGDQDTGDLVLLDV
CPLTLGIETVGGVMTKLIPRNTVVPTKKSQIFSTASDNQPTVTIKVYEGERPLTKDNHLL
GTFDLTGIPPAPRGVPQIEVTFEIDVNGILRVTAEDKGTGNKNKITITNDQNRLTPEEIE
RMVNDAEKFAEEDKKLKERIDTRNELESYAYSLKNQIGDKEKLGGKLSSEDKETMEKAVE
EKIEWLESHQDADIEDFKAKKKELEEIVQPIISKLYGSGGPPPTGEEDTSEKDEL |
NT seq |
1968 nt +upstreamnt +downstreamnt
atgatgaagttcactgtggtggcggcggcgttgctgctgctgggcgcggtgcgggccgag
gaggaggacaagaaggaggatgtgggcacggtggtcggcatcgacttggggaccacctat
tcctgcgtcggtgtgttcaagaacggccgcgtggagatcatagccaacgatcagggcaac
cgcatcacgccgtcgtatgtggccttcactcctgaaggggagcgtctgattggcgatgcg
gccaagaaccaactcacgtccaaccccgagaacacggtcttcgatgccaagcgcctcatc
ggacgcacttggaatgacccttcggtgcagcaggacatcaagttcttgccattcaaggtg
gttgaaaagaaaactaaaccgtacattcaagttgatattggaggtgggcaaaccaagaca
tttgccccagaagaaatttctgccatggttctcactaaaatgaaggagactgctgaggcg
tatttgggaaagaaggttacccatgcagttgttactgtaccagcttacttcaatgatgcc
cagcgacaagcaaccaaagatgctggcactattgctggactgaatgtcatgaggatcatc
aatgagcctacagcagctgctattgcatatggcctggataagagagagggagagaagaac
atccttgtgtttgacctgggtggcggcaccttcgatgtgtctcttctcaccattgacaat
ggtgtctttgaagtggtggccactaatggagatactcacctgggtggggaagactttgat
cagcgggtcatggaacacttcatcaagttgtacaaaaagaaaactggtaaagatgttagg
aaagacaacagagctgtgcagaaactccggcgtgaggtagaaaaggctaagagagccttg
tcttctcagcatcaagcaaggattgaaattgagtccttcttcgaaggagaagacttctca
gagacccttactcgggccaaatttgaagagctgaacatggacctgttccgctctaccatg
aagcctgtccagaaagtgttggaagactctgatctgaagaaatctgatattgatgaaatt
gttctggttggtggatctactcgaattccaaagattcagcaactggtgaaagagttcttc
aatggcaaggagccatcccgtggcataaaccccgatgaggctgtagcctatggtgccgct
gtccaggctggtgtcctctctggtgatcaggatacaggtgatctggtactgcttgatgtt
tgtccccttacacttggtattgaaactgtgggaggagtcatgacaaaactgattccaagg
aacactgtggtacccaccaagaagtctcagatcttctccacggcttccgataatcagcca
actgtaacaatcaaggtctatgaaggtgaacgacccctaacaaaagacaatcatcttctg
ggtacatttgatctgactggaattcctcctgctccccgtggagttccccagattgaagtc
acttttgagatagatgttaatggtattctccgagtgacagctgaagacaaaggtacagga
aacaaaaacaaaatcacaattaccaatgaccaaaaccgcctgacacctgaagaaattgaa
aggatggttaatgatgctgagaagtttgctgaggaagacaaaaagctcaaagagcgcatt
gacaccaggaatgaattggaaagctatgcttattctctcaagaaccagattggagataaa
gaaaagctgggaggtaaactttcttctgaagataaagaaaccatggaaaaagctgtagag
gaaaagattgaatggctggaaagccaccaggatgcggacattgaagactttaaagccaaa
aagaaggaactagaagaaattgttcagccaattatcagcaaactctatggaagtggaggc
cctcccccaactggtgaagaggatacatcagaaaaagatgagttgtag |