KEGG   Mus musculus (house mouse): 14872
Entry
14872             CDS       T01002                                 
Symbol
Gstt2, Yrs, mGSTT2
Name
(RefSeq) glutathione S-transferase theta-2
  KO
K00799  glutathione S-transferase [EC:2.5.1.18]
Organism
mmu  Mus musculus (house mouse)
Pathway
mmu00480  Glutathione metabolism
mmu00980  Metabolism of xenobiotics by cytochrome P450
mmu00982  Drug metabolism - cytochrome P450
mmu00983  Drug metabolism - other enzymes
mmu01100  Metabolic pathways
mmu01524  Platinum drug resistance
mmu05200  Pathways in cancer
mmu05204  Chemical carcinogenesis - DNA adducts
mmu05207  Chemical carcinogenesis - receptor activation
mmu05208  Chemical carcinogenesis - reactive oxygen species
mmu05225  Hepatocellular carcinoma
mmu05418  Fluid shear stress and atherosclerosis
Brite
KEGG Orthology (KO) [BR:mmu00001]
 09100 Metabolism
  09106 Metabolism of other amino acids
   00480 Glutathione metabolism
    14872 (Gstt2)
  09111 Xenobiotics biodegradation and metabolism
   00980 Metabolism of xenobiotics by cytochrome P450
    14872 (Gstt2)
   00982 Drug metabolism - cytochrome P450
    14872 (Gstt2)
   00983 Drug metabolism - other enzymes
    14872 (Gstt2)
 09160 Human Diseases
  09161 Cancer: overview
   05200 Pathways in cancer
    14872 (Gstt2)
   05204 Chemical carcinogenesis - DNA adducts
    14872 (Gstt2)
   05207 Chemical carcinogenesis - receptor activation
    14872 (Gstt2)
   05208 Chemical carcinogenesis - reactive oxygen species
    14872 (Gstt2)
  09162 Cancer: specific types
   05225 Hepatocellular carcinoma
    14872 (Gstt2)
  09166 Cardiovascular disease
   05418 Fluid shear stress and atherosclerosis
    14872 (Gstt2)
  09176 Drug resistance: antineoplastic
   01524 Platinum drug resistance
    14872 (Gstt2)
 09180 Brite Hierarchies
  09183 Protein families: signaling and cellular processes
   02000 Transporters [BR:mmu02000]
    14872 (Gstt2)
Enzymes [BR:mmu01000]
 2. Transferases
  2.5  Transferring alkyl or aryl groups, other than methyl groups
   2.5.1  Transferring alkyl or aryl groups, other than methyl groups (only sub-subclass identified to date)
    2.5.1.18  glutathione transferase
     14872 (Gstt2)
Transporters [BR:mmu02000]
 Other transporters
  Pores ion channels [TC:1]
   14872 (Gstt2)
SSDB
Motif
Pfam: GST_N GST_C GST_N_3 GST_N_2 GST_C_3 GST_C_2 Arc1p_N_like GST_N_4 Oxidored_nitro
Other DBs
NCBI-GeneID: 14872
NCBI-ProteinID: NP_034491
MGI: 106188
Ensembl: ENSMUSG00000033318
UniProt: Q61133
Position
10:complement(75667676..75673253)
AA seq 244 aa
MGLELYLDLLSQPSRAVYIFAKKNGIPFQTRTVDILKGQHMSEQFSQVNCLNKVPVLKDG
SFVLTESTAILIYLSSKYQVADHWYPADLQARAQVHEYLGWHADNIRGTFGVLLWTKVLG
PLIGVQVPQEKVERNRDRMVLVLQQLEDKFLRDRAFLVGQQVTLADLMSLEELMQPVALG
YNLFEGRPQLTAWRERVEAFLGAELCQEAHSTILSILGQAAKKMLPVPPPEVHASMQLRI
ARIP
NT seq 735 nt   +upstreamnt  +downstreamnt
atgggcttggagctctacctggacctgctgtcacaacccagccgcgctgtctacatcttc
gccaagaagaatggcatccccttccagacgcgtaccgtggatatactcaaagggcagcac
atgagcgagcaattctcccaggtgaactgcttaaacaaagttcctgtactcaaagacgga
agcttcgtgttgaccgaaagcacagccatcttgatttacctgagttccaagtaccaggtg
gcagaccactggtacccggccgacctacaggcccgtgcccaagtccacgaatacctgggc
tggcatgccgacaacatccgtggtactttcggagtgctcctatggaccaaggtgttgggg
ccactcattggggtccaggttccccaggagaaggtggaacggaacagagatagaatggtc
ctggttctgcaacagctggaggacaagttcctcagggacagggccttccttgttggccag
caggtgacgctagcggatctcatgtctctggaggagttgatgcagcccgtggctcttggc
tataacctgtttgagggacggcctcagctgacagcatggcgagagagggtggaggcgttc
ttgggtgctgagctgtgtcaggaggctcatagcaccatcctgagcatcctgggacaggca
gccaagaaaatgttaccagtaccccctccggaggtccatgccagcatgcagcttcgaatt
gctaggattccttga

  All links  
Gene (4)   
   NCBI-PROTEINID (1)   
   NCBI-Gene (1)   
   Ensembl (1)   
   OC (1)   
Protein sequence (13)   
   UniProt (1)   
   SWISS-PROT (1)   
   RefSeq(pep) (11)   
DNA sequence (27)   
   RefSeq(nuc) (11)   
   GenBank (8)   
   EMBL (8)   
Protein domain (9)   
   Pfam (9)   
All databases (53)   

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