KEGG   Mus musculus (mouse): 14964
Entry
14964             CDS       T01002                                 

Gene name
H2-D1, H-2D, H2-D, H2-K1
Definition
(RefSeq) histocompatibility 2, D region locus 1
  KO
K06751  MHC class I antigen
Organism
mmu  Mus musculus (mouse)
Pathway
mmu04144  Endocytosis
mmu04145  Phagosome
mmu04218  Cellular senescence
mmu04514  Cell adhesion molecules
mmu04612  Antigen processing and presentation
mmu04650  Natural killer cell mediated cytotoxicity
mmu04940  Type I diabetes mellitus
mmu05163  Human cytomegalovirus infection
mmu05165  Human papillomavirus infection
mmu05166  Human T-cell leukemia virus 1 infection
mmu05167  Kaposi sarcoma-associated herpesvirus infection
mmu05168  Herpes simplex virus 1 infection
mmu05169  Epstein-Barr virus infection
mmu05170  Human immunodeficiency virus 1 infection
mmu05203  Viral carcinogenesis
mmu05320  Autoimmune thyroid disease
mmu05330  Allograft rejection
mmu05332  Graft-versus-host disease
mmu05416  Viral myocarditis
Brite
KEGG Orthology (KO) [BR:mmu00001]
 09130 Environmental Information Processing
  09133 Signaling molecules and interaction
   04514 Cell adhesion molecules
    14964 (H2-D1)
 09140 Cellular Processes
  09141 Transport and catabolism
   04144 Endocytosis
    14964 (H2-D1)
   04145 Phagosome
    14964 (H2-D1)
  09143 Cell growth and death
   04218 Cellular senescence
    14964 (H2-D1)
 09150 Organismal Systems
  09151 Immune system
   04650 Natural killer cell mediated cytotoxicity
    14964 (H2-D1)
   04612 Antigen processing and presentation
    14964 (H2-D1)
 09160 Human Diseases
  09161 Cancer: overview
   05203 Viral carcinogenesis
    14964 (H2-D1)
  09172 Infectious disease: viral
   05166 Human T-cell leukemia virus 1 infection
    14964 (H2-D1)
   05170 Human immunodeficiency virus 1 infection
    14964 (H2-D1)
   05168 Herpes simplex virus 1 infection
    14964 (H2-D1)
   05163 Human cytomegalovirus infection
    14964 (H2-D1)
   05167 Kaposi sarcoma-associated herpesvirus infection
    14964 (H2-D1)
   05169 Epstein-Barr virus infection
    14964 (H2-D1)
   05165 Human papillomavirus infection
    14964 (H2-D1)
  09163 Immune disease
   05320 Autoimmune thyroid disease
    14964 (H2-D1)
   05330 Allograft rejection
    14964 (H2-D1)
   05332 Graft-versus-host disease
    14964 (H2-D1)
  09166 Cardiovascular disease
   05416 Viral myocarditis
    14964 (H2-D1)
  09167 Endocrine and metabolic disease
   04940 Type I diabetes mellitus
    14964 (H2-D1)
 09180 Brite Hierarchies
  09183 Protein families: signaling and cellular processes
   04147 Exosome [BR:mmu04147]
    14964 (H2-D1)
   00537 Glycosylphosphatidylinositol (GPI)-anchored proteins [BR:mmu00537]
    14964 (H2-D1)
Exosome [BR:mmu04147]
 Exosomal proteins
  Proteins found in most exosomes
   14964 (H2-D1)
Glycosylphosphatidylinositol (GPI)-anchored proteins [BR:mmu00537]
 Antigens
  14964 (H2-D1)
SSDB
Motif
Pfam: MHC_I C1-set Ig_3 MHC_I_C ig Ig_2 C2-set_2 Marek_A Omp85
Other DBs
NCBI-GeneID: 14964
NCBI-ProteinID: NP_034510
MGI: 95896
Ensembl: ENSMUSG00000073411
Vega: OTTMUSG00000037094
UniProt: P01899 Q792Z7
Structure
PDB: 

Position
17 B1; 17 18.61 cM
AA seq 362 aa
MGAMAPRTLLLLLAAALAPTQTRAGPHSMRYFETAVSRPGLEEPRYISVGYVDNKEFVRF
DSDAENPRYEPRAPWMEQEGPEYWERETQKAKGQEQWFRVSLRNLLGYYNQSAGGSHTLQ
QMSGCDLGSDWRLLRGYLQFAYEGRDYIALNEDLKTWTAADMAAQITRRKWEQSGAAEHY
KAYLEGECVEWLHRYLKNGNATLLRTDSPKAHVTHHPRSKGEVTLRCWALGFYPADITLT
WQLNGEELTQDMELVETRPAGDGTFQKWASVVVPLGKEQNYTCRVYHEGLPEPLTLRWEP
PPSTDSYMVIVAVLGVLGAMAIIGAVVAFVMKRRRNTGGKGGDYALAPGSQSSEMSLRDC
KA
NT seq 1089 nt   +upstreamnt  +downstreamnt
atgggggcgatggctccgcgcacgctgctcctgctgctggcggccgccctggccccgact
cagacccgcgcgggcccacactcgatgcggtatttcgagaccgccgtgtcccggcccggc
ctcgaggagccccggtacatctctgtcggctatgtggacaacaaggagttcgtgcgcttc
gacagcgacgcggagaatccgagatatgagccgcgggcgccgtggatggagcaggagggg
ccggagtattgggagcgggaaacacagaaagccaagggccaagagcagtggttccgagtg
agcctgaggaacctgctcggctactacaaccagagcgcgggcggctctcacacactccag
cagatgtctggctgtgacttggggtcggactggcgcctcctccgcgggtacctgcagttc
gcctatgaaggccgcgattacatcgccctgaacgaagacctgaaaacgtggacggcggcg
gacatggcggcgcagatcacccgacgcaagtgggagcagagtggtgctgcagagcattac
aaggcctacctggagggcgagtgcgtggagtggctccacagatacctgaagaacgggaac
gcgacgctgctgcgcacagattccccaaaggcacatgtgacccatcaccccagatctaaa
ggtgaagtcaccctgaggtgctgggccctgggcttctaccctgctgacatcaccctgacc
tggcagttgaatggggaggagctgacccaggacatggagcttgtggagaccaggcctgca
ggggatggaaccttccagaagtgggcatctgtggtggtgcctcttgggaaggagcagaat
tacacatgccgtgtgtaccatgaggggctgcctgagcccctcaccctgagatgggagcct
cctccgtccactgactcttacatggtgatcgttgctgttctgggtgtccttggagctatg
gccatcattggagctgtggtggcttttgtgatgaagagaaggagaaacacaggtggaaaa
ggaggggactatgctctggctccaggctcccagagctctgaaatgtctctccgagattgt
aaagcgtga

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