KEGG   Mus musculus (mouse): 15002
Entry
15002             CDS       T01002                                 

Gene name
H2-Ob, A-bet, A-beta, A-beta-2, A-beta2, H-2, H-2Ab, H-2I, H-2O, H-2Ob, H2-A, H2-Ab, H2-Ab2, H2-IA, H2-IAb2, O, Ob, vi, vic1
Definition
(RefSeq) histocompatibility 2, O region beta locus
  KO
K06752  MHC class II antigen
Organism
mmu  Mus musculus (mouse)
Pathway
mmu04145  Phagosome
mmu04514  Cell adhesion molecules
mmu04612  Antigen processing and presentation
mmu04640  Hematopoietic cell lineage
mmu04658  Th1 and Th2 cell differentiation
mmu04659  Th17 cell differentiation
mmu04672  Intestinal immune network for IgA production
mmu04940  Type I diabetes mellitus
mmu05140  Leishmaniasis
mmu05145  Toxoplasmosis
mmu05150  Staphylococcus aureus infection
mmu05152  Tuberculosis
mmu05164  Influenza A
mmu05166  Human T-cell leukemia virus 1 infection
mmu05168  Herpes simplex virus 1 infection
mmu05169  Epstein-Barr virus infection
mmu05310  Asthma
mmu05320  Autoimmune thyroid disease
mmu05321  Inflammatory bowel disease
mmu05322  Systemic lupus erythematosus
mmu05323  Rheumatoid arthritis
mmu05330  Allograft rejection
mmu05332  Graft-versus-host disease
mmu05416  Viral myocarditis
Brite
KEGG Orthology (KO) [BR:mmu00001]
 09130 Environmental Information Processing
  09133 Signaling molecules and interaction
   04514 Cell adhesion molecules
    15002 (H2-Ob)
 09140 Cellular Processes
  09141 Transport and catabolism
   04145 Phagosome
    15002 (H2-Ob)
 09150 Organismal Systems
  09151 Immune system
   04640 Hematopoietic cell lineage
    15002 (H2-Ob)
   04612 Antigen processing and presentation
    15002 (H2-Ob)
   04658 Th1 and Th2 cell differentiation
    15002 (H2-Ob)
   04659 Th17 cell differentiation
    15002 (H2-Ob)
   04672 Intestinal immune network for IgA production
    15002 (H2-Ob)
 09160 Human Diseases
  09163 Immune disease
   05310 Asthma
    15002 (H2-Ob)
   05322 Systemic lupus erythematosus
    15002 (H2-Ob)
   05323 Rheumatoid arthritis
    15002 (H2-Ob)
   05320 Autoimmune thyroid disease
    15002 (H2-Ob)
   05321 Inflammatory bowel disease
    15002 (H2-Ob)
   05330 Allograft rejection
    15002 (H2-Ob)
   05332 Graft-versus-host disease
    15002 (H2-Ob)
  09166 Cardiovascular disease
   05416 Viral myocarditis
    15002 (H2-Ob)
  09167 Endocrine and metabolic disease
   04940 Type I diabetes mellitus
    15002 (H2-Ob)
  09171 Infectious disease: bacterial
   05150 Staphylococcus aureus infection
    15002 (H2-Ob)
   05152 Tuberculosis
    15002 (H2-Ob)
  09172 Infectious disease: viral
   05166 Human T-cell leukemia virus 1 infection
    15002 (H2-Ob)
   05164 Influenza A
    15002 (H2-Ob)
   05168 Herpes simplex virus 1 infection
    15002 (H2-Ob)
   05169 Epstein-Barr virus infection
    15002 (H2-Ob)
  09174 Infectious disease: parasitic
   05145 Toxoplasmosis
    15002 (H2-Ob)
   05140 Leishmaniasis
    15002 (H2-Ob)
 09180 Brite Hierarchies
  09183 Protein families: signaling and cellular processes
   04147 Exosome [BR:mmu04147]
    15002 (H2-Ob)
Exosome [BR:mmu04147]
 Exosomal proteins
  Exosomal proteins of haemopoietic cells  (B-cell, T-cell, DC-cell, reticulocyte, and mast cell)
   15002 (H2-Ob)
  Exosomal proteins of epithelial cells
   15002 (H2-Ob)
  Exosomal proteins of breast milk
   15002 (H2-Ob)
SSDB
Motif
Pfam: MHC_II_beta C1-set Ig_3 DUF1538 C2-set_2 MHC_I
Other DBs
NCBI-GeneID: 15002
NCBI-ProteinID: NP_034519
MGI: 95925
Ensembl: ENSMUSG00000041538
Vega: OTTMUSG00000037093
UniProt: Q3U1X7 O35424
Position
17 B1; 17 17.98 cM
AA seq 271 aa
MGAGRAPWVVALLVNLMRLDSFMIEGRDSPENFVIQAKADCYFTNGTEKVHLLVRFIFNL
EEYLHFDSDLGMFVALTELGEPDADQWNKRLDLLETSRAAVNMVCRQKYKLGAPFTVERN
VPPEVTVYPERTPLLQQHNLLLCSVTGFYPGDISVKWFRNGQEERSGVMSTGLVRNGDWT
FQTTVMLEMIPELGDIYSCLVEHPGLLRPVSVAWMAQSEYSWKKILSGAAVFLLGLIVFL
VGVVIHLKAQKASVETQPGNEASRESLHSQP
NT seq 816 nt   +upstreamnt  +downstreamnt
atgggcgctgggagggccccctgggtggtggctctgttggtgaacctcatgaggctggat
tccttcatgattgaaggcagagactccccagagaattttgtgattcaggcaaaggcggac
tgttacttcaccaatggtacagaaaaggttcacttgctggtcaggttcatcttcaacctg
gaggagtatttacacttcgacagtgacctggggatgtttgtggctctgacggagctgggg
gaacctgatgctgaccagtggaacaaacgcctggatctcctggagacgagcagagctgct
gtgaacatggtctgcaggcagaagtacaagctgggggcccccttcactgtggagagaaat
gtgcctccagaggtgacagtgtatccagagaggaccccgttgctgcagcagcacaacctg
ctgctctgctctgtgacaggcttctaccccggggacataagtgtcaagtggttccggaat
ggacaggaggagaggtctggggtcatgtccactggccttgttaggaatggagactggacc
ttccagacaacagtaatgctggaaatgatcccagagcttggtgacatctacagctgcctc
gtggagcaccccggcctcctgagacctgtttctgtggcatggatggctcagtctgaatat
tcctggaaaaagatactgagtggagctgcagtgttcctgcttgggctgattgtcttcctg
gtgggggttgttatccatctcaaggctcagaaagcatctgtggagactcagcctggcaat
gaggcctcaagagagagtctccattctcaaccctag

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