KEGG   Mus musculus (mouse): 15015Help
Entry
15015             CDS       T01002                                 

Gene name
H2-Q4, H-2Q4, H2-D1, H2-Gs10, Qa-4, Qa4, Qat-4, Qb-1, Qb1
Definition
(RefSeq) histocompatibility 2, Q region locus 4
  KO
K06751  MHC class I antigen
Organism
mmu  Mus musculus (mouse)
Pathway
mmu04144  Endocytosis
mmu04145  Phagosome
mmu04218  Cellular senescence
mmu04514  Cell adhesion molecules (CAMs)
mmu04612  Antigen processing and presentation
mmu04940  Type I diabetes mellitus
mmu05163  Human cytomegalovirus infection
mmu05165  Human papillomavirus infection
mmu05166  Human T-cell leukemia virus 1 infection
mmu05167  Kaposi sarcoma-associated herpesvirus infection
mmu05168  Herpes simplex virus 1 infection
mmu05169  Epstein-Barr virus infection
mmu05170  Human immunodeficiency virus 1 infection
mmu05203  Viral carcinogenesis
mmu05320  Autoimmune thyroid disease
mmu05330  Allograft rejection
mmu05332  Graft-versus-host disease
mmu05416  Viral myocarditis
Brite
KEGG Orthology (KO) [BR:mmu00001]
 09130 Environmental Information Processing
  09133 Signaling molecules and interaction
   04514 Cell adhesion molecules (CAMs)
    15015 (H2-Q4)
 09140 Cellular Processes
  09141 Transport and catabolism
   04144 Endocytosis
    15015 (H2-Q4)
   04145 Phagosome
    15015 (H2-Q4)
  09143 Cell growth and death
   04218 Cellular senescence
    15015 (H2-Q4)
 09150 Organismal Systems
  09151 Immune system
   04650 Natural killer cell mediated cytotoxicity
    15015 (H2-Q4)
   04612 Antigen processing and presentation
    15015 (H2-Q4)
 09160 Human Diseases
  09161 Cancer: overview
   05203 Viral carcinogenesis
    15015 (H2-Q4)
  09163 Immune disease
   05320 Autoimmune thyroid disease
    15015 (H2-Q4)
   05330 Allograft rejection
    15015 (H2-Q4)
   05332 Graft-versus-host disease
    15015 (H2-Q4)
  09166 Cardiovascular disease
   05416 Viral myocarditis
    15015 (H2-Q4)
  09167 Endocrine and metabolic disease
   04940 Type I diabetes mellitus
    15015 (H2-Q4)
  09172 Infectious disease: viral
   05166 Human T-cell leukemia virus 1 infection
    15015 (H2-Q4)
   05170 Human immunodeficiency virus 1 infection
    15015 (H2-Q4)
   05168 Herpes simplex virus 1 infection
    15015 (H2-Q4)
   05163 Human cytomegalovirus infection
    15015 (H2-Q4)
   05167 Kaposi sarcoma-associated herpesvirus infection
    15015 (H2-Q4)
   05169 Epstein-Barr virus infection
    15015 (H2-Q4)
   05165 Human papillomavirus infection
    15015 (H2-Q4)
 09180 Brite Hierarchies
  09183 Protein families: signaling and cellular processes
   04147 Exosome [BR:mmu04147]
    15015 (H2-Q4)
   00537 Glycosylphosphatidylinositol (GPI)-anchored proteins [BR:mmu00537]
    15015 (H2-Q4)
Exosome [BR:mmu04147]
 Exosomal proteins
  Proteins found in most exosomes
   15015 (H2-Q4)
Glycosylphosphatidylinositol (GPI)-anchored proteins [BR:mmu00537]
 Antigens
  15015 (H2-Q4)
BRITE hierarchy
SSDB OrthologParalogGFIT
Motif
Pfam: MHC_I C1-set ig MHC_I_3 Ig_2 C2-set_2
Motif
Other DBs
NCBI-GeneID: 15015
NCBI-ProteinID: NP_001137161
MGI: 95933
Ensembl: ENSMUSG00000035929
Vega: OTTMUSG00000037138
UniProt: Q8HWB2 Q0WXH7
Position
17 B1; 17 18.65 cM
AA seq 354 aa AA seqDB search
MASTMLLLLVAVAQTLIEIRAAPRPAPLPARSPAGGPGRSSGSHRALPPGPHLLSYFYTS
VSRPGLGEPRFISVGYVDNTEFVRFDSDAENPRYEPRAPWMEQEGPEYWERETQKAKGNE
QIFRVNLRTLLSYYNQSAGGSHTIQVISGCEVGSDGRLLRGYQQFAYDGRDYIALNEDLK
TWTAADMAAQITRRKWEQAGATEKSKAYLEGACVQSLRRYLELGKETLLRTDPPKAHVTC
HHRSDGDVTLRCWALGFYPANIILTWQLNGEELTQDMELVETRPSGDGTFQKWASVVVPL
GKEQNYTCHVHHEGLPEPLTLRWEPPPSTVSNMANVAVLVVLGAWPSLQLWWLL
NT seq 1065 nt NT seq  +upstreamnt  +downstreamnt
atggcgtcaacaatgctgcttctgctggtggcagtcgcccagaccctgatcgagatccgc
gcggccccgcgccctgctcccctcccggcccgctcacccgccgggggtcccggaaggagt
tcggggtctcaccgcgccctgcctccaggcccacacttgctgagttatttctacacctcc
gtgtcccggccgggccttggggagccccggttcatctctgtcggttacgtggacaacacg
gagttcgtgcgcttcgacagcgacgcggagaatccgagatatgagccgcgggcaccgtgg
atggagcaggaggggccggagtattgggagcgggaaacacagaaagccaagggcaatgag
cagattttccgagtgaacctgaggaccctgctcagctactacaaccagagcgcgggcggc
tctcacactattcaggtgatctctggctgtgaagtggggtccgacgggcgcctcctccgc
gggtaccagcagttcgcctacgacggccgcgattacatcgccctgaacgaagacctgaaa
acgtggacggcggcggacatggcggcacagatcacccgacgcaagtgggagcaggctggt
gctacagagaaaagcaaggcctacctggagggcgcgtgcgtgcagtccctccgcagatac
ctggagctcgggaaggagacgctgctgcgcacagatcctccaaaggcacatgtgacatgt
caccacagatctgacggtgatgtcaccctgaggtgctgggccctgggcttctaccctgct
aacatcatcctgacctggcagttgaatggggaggagctgacccaggacatggagcttgtg
gagaccaggccttcaggggatggaaccttccagaagtgggcatctgtggtggtgcctctt
gggaaggagcagaattacacatgccatgtgcaccatgaggggctgcctgagcccctcacc
ctgagatgggagcctcctccatccactgtctccaacatggcgaacgtagctgttctggtt
gtccttggagcttggccatcattgcagctgtggtggcttttgtga

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