KEGG   Mus musculus (house mouse): 15170
Entry
15170             CDS       T01002                                 
Symbol
Ptpn6, 70Z-SHP, Hcph, PTPTY-42, Ptp1C, SH-PTP1, SHP-1, hcp, me
Name
(RefSeq) protein tyrosine phosphatase, non-receptor type 6
  KO
K05697  tyrosine-protein phosphatase non-receptor type 6 [EC:3.1.3.48]
Organism
mmu  Mus musculus (house mouse)
Pathway
mmu04148  Efferocytosis
mmu04520  Adherens junction
mmu04630  JAK-STAT signaling pathway
mmu04650  Natural killer cell mediated cytotoxicity
mmu04660  T cell receptor signaling pathway
mmu04662  B cell receptor signaling pathway
mmu05140  Leishmaniasis
mmu05205  Proteoglycans in cancer
mmu05235  PD-L1 expression and PD-1 checkpoint pathway in cancer
Brite
KEGG Orthology (KO) [BR:mmu00001]
 09130 Environmental Information Processing
  09132 Signal transduction
   04630 JAK-STAT signaling pathway
    15170 (Ptpn6)
 09140 Cellular Processes
  09141 Transport and catabolism
   04148 Efferocytosis
    15170 (Ptpn6)
 09150 Organismal Systems
  09151 Immune system
   04650 Natural killer cell mediated cytotoxicity
    15170 (Ptpn6)
   04660 T cell receptor signaling pathway
    15170 (Ptpn6)
   04662 B cell receptor signaling pathway
    15170 (Ptpn6)
 09160 Human Diseases
  09161 Cancer: overview
   05205 Proteoglycans in cancer
    15170 (Ptpn6)
   05235 PD-L1 expression and PD-1 checkpoint pathway in cancer
    15170 (Ptpn6)
  09174 Infectious disease: parasitic
   05140 Leishmaniasis
    15170 (Ptpn6)
 09180 Brite Hierarchies
  09181 Protein families: metabolism
   01009 Protein phosphatases and associated proteins [BR:mmu01009]
    15170 (Ptpn6)
Enzymes [BR:mmu01000]
 3. Hydrolases
  3.1  Acting on ester bonds
   3.1.3  Phosphoric-monoester hydrolases
    3.1.3.48  protein-tyrosine-phosphatase
     15170 (Ptpn6)
Protein phosphatases and associated proteins [BR:mmu01009]
 Protein tyrosine phosphatases (PTPs)
  Class I PTPs (Classical)
   Non-receptor PTPs
    15170 (Ptpn6)
SSDB
Motif
Pfam: Y_phosphatase SH2 PTP-SAK SH2_1 Tc-R-P DSPc PTPlike_phytase Y_phosphatase3 PTP-NADK HGAL
Other DBs
NCBI-GeneID: 15170
NCBI-ProteinID: NP_038573
MGI: 96055
Ensembl: ENSMUSG00000004266
UniProt: P29351 Q3UB72
Position
6:complement(124697670..124715672)
AA seq 595 aa
MVRWFHRDLSGPDAETLLKGRGVPGSFLARPSRKNQGDFSLSVRVDDQVTHIRIQNSGDF
YDLYGGEKFATLTELVEYYTQQQGILQDRDGTIIHLKYPLNCSDPTSERWYHGHISGGQA
ESLLQAKGEPWTFLVRESLSQPGDFVLSVLNDQPKAGPGSPLRVTHIKVMCEGGRYTVGG
SETFDSLTDLVEHFKKTGIEEASGAFVYLRQPYYATRVNAADIENRVLELNKKQESEDTA
KAGFWEEFESLQKQEVKNLHQRLEGQRPENKSKNRYKNILPFDHSRVILQGRDSNIPGSD
YINANYVKNQLLGPDENSKTYIASQGCLDATVNDFWQMAWQENTRVIVMTTREVEKGRNK
CVPYWPEVGTQRVYGLYSVTNSREHDTAEYKLRTLQISPLDNGDLVREIWHYQYLSWPDH
GVPSEPGGVLSFLDQINQRQESLPHAGPIIVHCSAGIGRTGTIIVIDMLMESISTKGLDC
DIDIQKTIQMVRAQRSGMVQTEAQYKFIYVAIAQFIETTKKKLEIIQSQKGQESEYGNIT
YPPAVRSAHAKASRTSSKHKEEVYENVHSKSKKEEKVKKQRSADKEKNKGSLKRK
NT seq 1788 nt   +upstreamnt  +downstreamnt
atggtgaggtggtttcaccgggacctcagcgggcctgatgcagagaccctgctgaagggc
cggggagtccctgggagcttcctggctcggcccagccgcaagaaccagggtgacttctcc
ctctcagtcagggtggatgatcaggtgactcatattcggatccagaactcaggggacttc
tatgacctgtacggaggggagaagtttgcgacgctgacagagctggtcgagtattacacg
cagcagcagggcatcctgcaggaccgagatggcaccatcatccaccttaagtacccactg
aactgctcggaccccaccagtgagaggtggtaccacggccacatatctggagggcaggcg
gagtcactgctgcaggccaagggcgagccctggacatttcttgtgcgtgagagtctcagc
caacctggtgattttgtgctctctgtgctcaatgaccagcccaaggctggcccaggttcc
ccgctcagggtcactcatatcaaggttatgtgtgagggtggacgctatactgtgggtggc
tcagagacgtttgacagcctcacagacctggtggagcacttcaagaagacagggattgag
gaggcctcgggtgcctttgtctacctgcggcagccttactacgctactcgggtaaacgca
gctgacattgagaatcgggtcttggaactgaacaagaagcaggagtcggaggacacagcc
aaggctggcttctgggaggagtttgagagtctacaaaagcaggaggtaaagaatctacac
caacgtctggaagggcagcggccagagaacaagagcaagaaccgctacaagaacattctt
ccctttgaccacagccgagtgatcctgcagggacgtgacagtaacatcccaggctctgac
tacatcaatgccaactacgtgaagaaccagctgctaggtccagatgagaactctaagacc
tacatcgccagccagggctgtctggatgccacagtcaatgacttctggcagatggcttgg
caggagaacactcgtgtcatcgtcatgactaccagagaggtggagaaaggccggaacaaa
tgtgtcccatactggcccgaggtgggcactcagcgtgtctatggtctctactctgtgacc
aacagtagggagcatgacacagcagaatacaaactgcgaacattacagatctccccacta
gacaatggggacctggttcgggagatatggcactaccagtacctgagctggcctgaccat
ggggttcccagtgagcctgggggtgtcctcagctttctggatcagatcaaccagcgacag
gaaagtttgcctcatgcagggcccatcattgtgcattgcagcgctggcatcggccgcacg
ggcaccatcatcgtcattgatatgcttatggaaagcatctccaccaaggggctagactgt
gacattgatatccagaagaccatccagatggtacgagcacagcgctccggcatggtgcag
accgaggcccagtacaagtttatttacgtggccattgcccagttcatcgaaacgaccaag
aagaaactggagatcatacaatcccagaagggccaggagtcggagtatgggaatatcacg
taccctcccgctgtgaggagtgcccacgccaaagcctcgcgtacttcctccaagcacaag
gaggaggtgtacgaaaacgtgcatagcaagagcaagaaggaagagaaagtaaagaagcag
cggtcggcagacaaggagaagaacaaaggttctctcaagaggaagtga

  All links  
Gene (6)   
   RefGene (1)   
   NCBI-PROTEINID (1)   
   NCBI-Gene (1)   
   Ensembl (1)   
   RIKEN BRC-DNA (1)   
   OC (1)   
Protein sequence (5)   
   UniProt (2)   
   SWISS-PROT (1)   
   RefSeq(pep) (2)   
DNA sequence (34)   
   RefSeq(nuc) (2)   
   GenBank (16)   
   EMBL (16)   
Protein domain (10)   
   Pfam (10)   
All databases (55)   

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