KEGG   Mus musculus (house mouse): 15185
Entry
15185             CDS       T01002                                 
Symbol
Hdac6, Hd6, Hdac5, Sfc6, mHDA2
Name
(RefSeq) histone deacetylase 6 isoform 2
  KO
K11407  histone deacetylase 6 [EC:3.5.1.98]
Organism
mmu  Mus musculus (house mouse)
Pathway
mmu04613  Neutrophil extracellular trap formation
mmu05014  Amyotrophic lateral sclerosis
mmu05034  Alcoholism
mmu05203  Viral carcinogenesis
Brite
KEGG Orthology (KO) [BR:mmu00001]
 09150 Organismal Systems
  09151 Immune system
   04613 Neutrophil extracellular trap formation
    15185 (Hdac6)
 09160 Human Diseases
  09161 Cancer: overview
   05203 Viral carcinogenesis
    15185 (Hdac6)
  09164 Neurodegenerative disease
   05014 Amyotrophic lateral sclerosis
    15185 (Hdac6)
  09165 Substance dependence
   05034 Alcoholism
    15185 (Hdac6)
 09180 Brite Hierarchies
  09181 Protein families: metabolism
   01009 Protein phosphatases and associated proteins [BR:mmu01009]
    15185 (Hdac6)
  09182 Protein families: genetic information processing
   03019 Messenger RNA biogenesis [BR:mmu03019]
    15185 (Hdac6)
   04131 Membrane trafficking [BR:mmu04131]
    15185 (Hdac6)
   03036 Chromosome and associated proteins [BR:mmu03036]
    15185 (Hdac6)
Enzymes [BR:mmu01000]
 3. Hydrolases
  3.5  Acting on carbon-nitrogen bonds, other than peptide bonds
   3.5.1  In linear amides
    3.5.1.98  histone deacetylase
     15185 (Hdac6)
Protein phosphatases and associated proteins [BR:mmu01009]
 Protein serine/threonine phosphatases
  Phosphoprotein phosphatases (PPPs)
   Protein phosphatase-1
    PP1-interacting proteins (PIPs)
     15185 (Hdac6)
Messenger RNA biogenesis [BR:mmu03019]
 Eukaryotic type
  mRNA surveillance and transport factors
   mRNA cycle factors
    Stress granule specific factors
     15185 (Hdac6)
Membrane trafficking [BR:mmu04131]
 Autophagy
  Aggrephagy
   Other aggrephagy associated proteins
    15185 (Hdac6)
Chromosome and associated proteins [BR:mmu03036]
 Eukaryotic type
  Histone modification proteins
   HDACs (histone deacetylases)
    Class II HDACs
     15185 (Hdac6)
SSDB
Motif
Pfam: Hist_deacetyl zf-UBP zf-UBP_var
Other DBs
NCBI-GeneID: 15185
NCBI-ProteinID: NP_001123888
MGI: 1333752
Ensembl: ENSMUSG00000031161
UniProt: Q9Z2V5
Position
X:complement(7796355..7814284)
AA seq 1149 aa
MTSTGQDSSTRQRKSRHNPQSPLQESSATLKRGGKKCAVPHSSPNLAEVKKKGKMKKLSQ
PAEEDLVVGLQGLDLNPETRVPVGTGLVFDEQLNDFHCLWDDSFPESPERLHAIREQLIL
EGLLGRCVSFQARFAEKEELMLVHSLEYIDLMETTQYMNEGELRVLAETYDSVYLHPNSY
SCACLATGSVLRLVDALMGAEIRNGMAVIRPPGHHAQHNLMDGYCMFNHLAVAARYAQKK
HRIQRVLIVDWDVHHGQGTQFIFDQDPSVLYFSIHRYEHGRFWPHLKASNWSTIGFGQGQ
GYTINVPWNQTGMRDADYIAAFLHILLPVASEFQPQLVLVAAGFDALHGDPKGEMAATPA
GFAHLTHLLMGLAGGKLILSLEGGYNLRALAKGVSASLHTLLGDPCPMLESCVVPCASAQ
TSIYCTLEALEPFWEVLERSVETQEEDEVEEAVLEEEEEEGGWEATALPMDTWPLLQNRT
GLVYDEKMMSHCNLWDNHHPETPQRILRIMCHLEEVGLAARCLILPARPALDSELLTCHS
AEYVEHLRTTEKMKTRDLHREGANFDSIYICPSTFACAKLATGAACRLVEAVLSGEVLNG
IAVVRPPGHHAEPNAACGFCFFNSVAVAARHAQIIAGRALRILIVDWDVHHGNGTQHIFE
DDPSVLYVSLHRYDRGTFFPMGDEGASSQVGRDAGIGFTVNVPWNGPRMGDADYLAAWHR
LVLPIAYEFNPELVLISAGFDAAQGDPLGGCQVTPEGYAHLTHLLMGLAGGRIILILEGG
YNLASISESMAACTHSLLGDPPPQLTLLRPPQSGALVSISEVIQVHRKYWRSLRLMKMED
KEECSSSRLVIKKLPPTASPVSAKEMTTPKGKVPEESVRKTIAALPGKESTLGQAKSKMA
KAVLAQGQSSEQAAKGTTLDLATSKETVGGATTDLWASAAAPENFPNQTTSVEALGETEP
TPPASHTNKQTTGASPLQGVTAQQSLQLGVLSTLELSREAEEAHDSEEGLLGEAAGGQDM
NSLMLTQGFGDFNTQDVFYAVTPLSWCPHLMAVCPIPAAGLDVSQPCKTCGTVQENWVCL
TCYQVYCSRYVNAHMVCHHEASEHPLVLSCVDLSTWCYVCQAYVHHEDLQDVKNAAHQNK
FGEDMPHSH
NT seq 3450 nt   +upstreamnt  +downstreamnt
atgacctccaccggccaagattcttctactagacagcgaaagagtaggcacaatccccag
tcaccccttcaggaatccagcgccaccttgaagcgtggtggaaagaagtgtgctgtaccc
cactccagccccaatctagcggaggtaaagaagaaaggcaaaatgaagaagctgagccaa
ccagctgaagaggacctagttgtggggcttcaagggctggatctgaaccctgagacaaga
gtgccagttggtactggattggtgtttgatgaacaactaaatgacttccattgcctttgg
gatgacagcttccctgaaagccctgagcggctccatgccatcagagagcaactgatcctg
gagggcctcctgggccgctgtgtgtcctttcaggcccggttcgctgagaaggaggagctg
atgttggttcacagcctggaatacattgatctgatggagacaacccagtacatgaatgaa
ggggagcttcgagtactggcagaaacctatgattcagtgtatctgcatccgaactcatat
tcctgtgcctgcctggctacaggctctgtcctccggctggtagatgcactcatgggggct
gagattcggaatggcatggccgtcatcaggcctcctggacaccatgctcagcacaatctt
atggatgggtattgcatgttcaaccatctggctgtggctgcccgctatgcgcaaaagaag
caccgcattcagagggttctcatcgtggactgggatgtgcaccatggtcaaggaacacag
ttcatcttcgaccaggaccccagtgtcctttatttctccatccaccgatatgaacatggt
cgcttctggccccaccttaaggcttctaactggtccactataggttttggccaaggccaa
ggatataccatcaatgtaccttggaaccagacgggcatgcgggacgctgactacattgct
gctttcctgcacatcctgctgccagttgcctcggagtttcagcctcaactggtcttggtg
gccgctggatttgatgccctccacggagaccccaagggagagatggctgccacgccagca
ggatttgcccacctaacccatttgctcatgggtttggcaggaggcaagttgattctgtcc
ctggagggtggctataacctccgtgccctggctaagggagtcagtgcttcactccacacc
cttcttggagacccttgccccatgctggagtcctgtgttgtaccttgtgcaagcgcccag
acttccatctactgcactctagaagcccttgaacccttctgggaggtcctggagagatca
gttgagacccaggaggaagatgaagtggaagaagccgtgctagaagaggaggaggaggaa
ggtggctgggaggccactgcactgcccatggatacatggccactgctccagaaccgcact
gggctggtctatgatgagaagatgatgagtcactgcaacctctgggacaatcatcaccct
gagacacctcagcgcatcttacgcatcatgtgtcacctggaggaggtgggccttgcggct
cgctgtctcatcctacctgctcggcctgccctggactctgagctccttacctgccacagt
gctgagtacgtggagcatctccgcaccacagaaaagatgaaaacccgggatctgcaccgt
gaaggtgccaactttgactccatctacatctgccccagcacctttgcctgcgcaaagctt
gccacaggcgctgcctgccgcctggtggaagctgtgctctcgggagaggttctaaatggc
attgcagtagtgcgccctccaggacaccacgcggagccaaatgctgcctgtggtttctgc
tttttcaactcagtagctgtagctgctcgccatgcccagatcattgctggacgtgccctg
cggatcctaatcgtggattgggatgttcatcatggtaatggaactcagcacatatttgag
gatgaccctagtgtattatacgtgtccctgcaccggtatgaccgtggcactttcttcccc
atgggggatgagggtgccagtagccaagtaggccgagatgcaggtataggcttcactgtc
aatgtgccctggaatgggccccgcatgggtgatgctgattacctggctgcatggcatcgt
ctggtacttcccatcgcctatgagtttaacccagaactggtgctgatctcagctggcttt
gatgctgcacaaggggatccgctggggggctgccaagtaacaccggagggttatgcccac
ctcacccacctactgatgggccttgctggtggccgtattattcttattctagagggtgga
tacaatttggcatctatctctgagtctatggctgcctgcacccattccctccttggagac
ccaccaccccagcttactttgctgcgaccgccacagtcaggagccctggtttcaatcagt
gaggtcatccaagtccatcgcaaatactggcgcagtttgcggttgatgaaaatggaagac
aaggaagaatgctctagttctaggcttgtcatcaagaagttgcccccaacagccagtcct
gtatcagctaaggaaatgaccacaccgaaaggaaaggttcctgaagaaagcgtgaggaag
accatagcagcactacctgggaaagagtctactctaggccaggctaaatcaaagatggct
aaggctgtgcttgctcagggccagtcctcagaacaagctgctaagggaactacactggat
ctggctacctcaaaggagactgtgggaggagccacgacggacctgtgggcctcagcagct
gctcctgaaaacttccctaaccagaccacctctgtggaggctttgggagaaactgagcca
acgcctccagcctcgcatacaaacaagcagaccacaggggcttcacctctgcagggagtc
acggctcagcagtccctacagcttggggttctcagcactttggagctaagcagagaagca
gaggaagcccatgattctgaggagggcctgctaggggaagccgctggaggtcaggacatg
aacagcttgatgctgacacaaggatttggggactttaatacccaggatgtattttatgct
gtgaccccactatcctggtgtccccatttgatggcagtatgccccattcctgcagcaggc
ctagatgtgtcccaaccttgtaagacctgtggaacagtccaggagaactgggtgtgtctg
acttgctatcaggtgtactgcagtcgctatgtcaatgcccatatggtctgccaccatgaa
gcctctgaacacccgctggtcctcagctgtgttgacctgtctacctggtgttatgtctgt
caggcttatgtccaccacgaggatctccaagatgtgaagaacgctgcccaccagaacaag
tttggggaggacatgccccactcacactaa

  All links  
Gene (47)   
   RefGene (41)   
   NCBI-PROTEINID (1)   
   NCBI-Gene (1)   
   Ensembl (1)   
   RIKEN BRC-DNA (2)   
   OC (1)   
Protein sequence (11)   
   UniProt (1)   
   SWISS-PROT (1)   
   RefSeq(pep) (9)   
DNA sequence (55)   
   RefSeq(nuc) (11)   
   GenBank (22)   
   EMBL (22)   
Protein domain (3)   
   Pfam (3)   
All databases (116)   

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