KEGG   Mus musculus (mouse): 15275
Entry
15275             CDS       T01002                                 

Gene name
Hk1, BB404130, Hk-1, Hk1-, Hk1-s, dea, mHk1-, mHk1-s
Definition
(RefSeq) hexokinase 1
  KO
K00844  hexokinase [EC:2.7.1.1]
Organism
mmu  Mus musculus (mouse)
Pathway
mmu00010  Glycolysis / Gluconeogenesis
mmu00051  Fructose and mannose metabolism
mmu00052  Galactose metabolism
mmu00500  Starch and sucrose metabolism
mmu00520  Amino sugar and nucleotide sugar metabolism
mmu00524  Neomycin, kanamycin and gentamicin biosynthesis
mmu01100  Metabolic pathways
mmu01200  Carbon metabolism
mmu04066  HIF-1 signaling pathway
mmu04910  Insulin signaling pathway
mmu04930  Type II diabetes mellitus
mmu04973  Carbohydrate digestion and absorption
mmu05230  Central carbon metabolism in cancer
Module
mmu_M00001  Glycolysis (Embden-Meyerhof pathway), glucose => pyruvate
mmu_M00549  Nucleotide sugar biosynthesis, glucose => UDP-glucose
mmu_M00892  UDP-N-acetyl-D-glucosamine biosynthesis, eukaryotes, glucose => UDP-GlcNAc
Brite
KEGG Orthology (KO) [BR:mmu00001]
 09100 Metabolism
  09101 Carbohydrate metabolism
   00010 Glycolysis / Gluconeogenesis
    15275 (Hk1)
   00051 Fructose and mannose metabolism
    15275 (Hk1)
   00052 Galactose metabolism
    15275 (Hk1)
   00500 Starch and sucrose metabolism
    15275 (Hk1)
   00520 Amino sugar and nucleotide sugar metabolism
    15275 (Hk1)
  09110 Biosynthesis of other secondary metabolites
   00524 Neomycin, kanamycin and gentamicin biosynthesis
    15275 (Hk1)
 09130 Environmental Information Processing
  09132 Signal transduction
   04066 HIF-1 signaling pathway
    15275 (Hk1)
 09150 Organismal Systems
  09152 Endocrine system
   04910 Insulin signaling pathway
    15275 (Hk1)
  09154 Digestive system
   04973 Carbohydrate digestion and absorption
    15275 (Hk1)
 09160 Human Diseases
  09161 Cancer: overview
   05230 Central carbon metabolism in cancer
    15275 (Hk1)
  09167 Endocrine and metabolic disease
   04930 Type II diabetes mellitus
    15275 (Hk1)
 09180 Brite Hierarchies
  09182 Protein families: genetic information processing
   04131 Membrane trafficking [BR:mmu04131]
    15275 (Hk1)
Enzymes [BR:mmu01000]
 2. Transferases
  2.7  Transferring phosphorus-containing groups
   2.7.1  Phosphotransferases with an alcohol group as acceptor
    2.7.1.1  hexokinase
     15275 (Hk1)
Membrane trafficking [BR:mmu04131]
 Autophagy
  Mitophagy
   Other mitophagy associated  proteins
    15275 (Hk1)
SSDB
Motif
Pfam: Hexokinase_2 Hexokinase_1 Sec23_helical
Other DBs
NCBI-GeneID: 15275
NCBI-ProteinID: NP_001139572
MGI: 96103
Ensembl: ENSMUSG00000037012
Vega: OTTMUSG00000034151
UniProt: Q6GQU1 Q3TTB4
Position
10 B4; 10 32.37 cM
AA seq 918 aa
MIAAQLLAYYFTELKDDQVKKIDKYLYAMRLSDEILIDILTRFKKEMKNGLSRDYNPTAS
VKMLPTFVRSIPDGSEKGDFIALDLGGSSFRILRVQVNHEKSQNVSMESEVYDTPENIVH
GSGSQLFDHVAECLGDFMEKRKIKDKKLPVGFTFSFPCRQSKIDEAVLITWTKRFKASGV
EGADVVKLLNKAIKKRGDYDANIVAVVNDTVGTMMTCGYDDQQCEVGLIIGTGTNACYME
ELRHIDLVEGDEGRMCINTEWGAFGDDGSLEDIRTEFDRELDRGSLNPGKQLFEKMVSGM
YMGELVRLILVKMAKESLLFEGRITPELLTRGKFTTSDVAAIETDKEGVQNAKEILTRLG
VEPSHDDCVSVQHVCTIVSFRSANLVAATLGAILNRLRDNKGTPRLRTTVGVDGSLYKMH
PQYSRRFHKTLRRLVPDSDVRFLLSESGSGKGAAMVTAVAYRLAEQHRQIEETLSHFRLS
KQALMEVKKKLRSEMEMGLRKETNSRATVKMLPSYVRSIPDGTEHGDFLALDLGGTNFRV
LLVKIRSGKKRTVEMHNKIYSIPLEIMQGTGDELFDHIVSCISDFLDYMGIKGPRMPLGF
TFSFPCKQTSLDCGILITWTKGFKATDCVGHDVATLLRDAVKRREEFDLDVVAVVNDTVG
TMMTCAYEEPSCEIGLIVGTGSNACYMEEMKNVEMVEGNQGQMCINMEWGAFGDNGCLDD
IRTDFDKVVDEYSLNSGKQRFEKMISGMYLGEIVRNILIDFTKKGFLFRGQISEPLKTRG
IFETKFLSQIESDRLALLQVRAILQQLGLNSTCDDSILVKTVCGVVSKRAAQLCGAGMAA
VVEKIRENRGLDHLNVTVGVDGTLYKLHPHFSRIMHQTVKELSPKCTVSFLLSEDGSGKG
AALITAVGVRLRGDPTNA
NT seq 2757 nt   +upstreamnt  +downstreamnt
atgatcgccgcgcaactactggcatattacttcaccgagctgaaggatgaccaagtcaaa
aagattgataagtatctgtatgccatgcggctctctgatgaaattctgatagatatcctg
acacgcttcaagaaagagatgaagaatggcctctcccgggattataacccaacggcctcc
gtcaagatgctgccaacctttgtccggtccattccggacggctcagaaaagggggatttc
attgcactggatctcggcgggtcttcctttcgaatcctgcgggtgcaggtgaaccacgag
aagagtcagaacgtcagcatggagtctgaggtctacgacaccccagagaacatcgtgcac
ggcagtggaagccagctttttgatcacgtcgctgaatgcctcggagacttcatggagaaa
aggaagatcaaggacaagaaattacccgtgggattcacgttttccttcccgtgccgacaa
tccaaaatagacgaggccgtactgatcacgtggacaaagcggttcaaagccagtggcgtg
gaaggggcggatgtggtcaagctgctgaataaagccattaagaagcgaggggactatgac
gctaacattgtagctgtggtgaatgacacagtggggaccatgatgacctgcggctacgat
gaccaacagtgtgaagtcggcctgatcattggcactggcaccaatgcttgctacatggag
gaactgcgacacatcgacctggtggaaggcgatgaggggaggatgtgtattaacacggaa
tggggagcctttggggatgatgggtccctggaagacattcgaacagagtttgacagagag
ttagaccggggatccctcaaccctgggaaacagctgttcgagaagatggtgagcggcatg
tacatgggggagctggtccggctgatcctggtgaagatggccaaggaaagcctcttattt
gaagggcgcattactccagagctgctcacgaggggcaagttcaccactagcgacgtagcc
gccattgaaacggataaggaaggcgttcaaaatgccaaggaaatcttgacccgcctggga
gtggagccgtctcacgatgactgcgtatcggtccagcacgtatgcacgatcgtctccttc
cgatcagccaacctggtggctgccacgctcggtgccatcttgaaccgcctgcgggacaat
aagggcacgcccaggctgcggaccacagttggcgtagacggttctctctacaagatgcac
ccacagtattcccggcggttccacaagaccctgaggcgcctggtgcctgactcggacgtc
cggttcctcctctcggagagtggcagtggcaagggagccgccatggtgaccgctgtggcc
taccgcctggccgagcagcaccggcagattgaggaaaccctgtcccacttccgcctcagc
aagcaggcactgatggaggtgaagaagaagctgcggtcagagatggaaatggggctgaga
aaggagaccaacagcagagctacggtcaaaatgctgccttcttatgttcggagcatccca
gatgggactgagcatggtgacttcctggccttggatctcggaggaacgaatttccgagtc
ctactggtaaagatccgtagtgggaaaaagagaacagtggagatgcacaacaagatctac
tccattcccctggaaatcatgcagggcaccggggatgagctgtttgatcacattgtctcc
tgcatctccgacttcctggactacatggggatcaaaggcccccggatgcctctgggcttc
accttctcgtttccctgcaagcagacgagcctagattgcggaatcttgatcacgtggaca
aagggattcaaagccaccgactgtgtgggtcacgatgtagccactttactgagggatgct
gtaaaaaggagagaggaatttgacctggatgtggtggctgtggtcaacgacaccgtgggc
accatgatgacttgtgcttatgaagaaccttcttgtgagattggactcatcgtggggact
ggcagcaatgcctgctacatggaggagatgaaaaacgtggagatggtggaggggaaccag
ggccagatgtgcatcaatatggaatggggtgcctttggtgacaacggctgtctggacgac
atcagaacagacttcgacaaagtggtggacgaatattctctaaacagtgggaaacaaagg
tttgagaagatgatcagtggaatgtacctgggtgagatcgtccgtaacatcctgattgac
ttcaccaagaaaggcttcctcttccggggacagatctctgagccactcaagacccgaggc
atcttcgagaccaagtttctctctcagatcgagagtgaccgattagcgctgctccaggtg
cgggccatccttcagcagctgggtctaaacagcacgtgcgacgacagtatcctggtcaag
accgtgtgtggggtggtgtccaagcgggcggcccagctgtgtggtgccggcatggccgcc
gtggtggaaaagatccgagagaacagaggcctagaccacctgaatgtaaccgtgggcgtg
gacgggacgctctacaaactccatccacacttctccagaatcatgcaccaaacagtgaag
gaactgtcaccaaagtgtaccgtgtccttcctcctgtctgaagacggcagcggcaagggg
gccgcccttatcacagctgtgggcgtgcggctcagaggagaccctacgaacgcctaa

KEGG   Mus musculus (mouse): 15277
Entry
15277             CDS       T01002                                 

Gene name
Hk2, AI642394, HK, HKII
Definition
(RefSeq) hexokinase 2
  KO
K00844  hexokinase [EC:2.7.1.1]
Organism
mmu  Mus musculus (mouse)
Pathway
mmu00010  Glycolysis / Gluconeogenesis
mmu00051  Fructose and mannose metabolism
mmu00052  Galactose metabolism
mmu00500  Starch and sucrose metabolism
mmu00520  Amino sugar and nucleotide sugar metabolism
mmu00524  Neomycin, kanamycin and gentamicin biosynthesis
mmu01100  Metabolic pathways
mmu01200  Carbon metabolism
mmu04066  HIF-1 signaling pathway
mmu04910  Insulin signaling pathway
mmu04930  Type II diabetes mellitus
mmu04973  Carbohydrate digestion and absorption
mmu05230  Central carbon metabolism in cancer
Module
mmu_M00001  Glycolysis (Embden-Meyerhof pathway), glucose => pyruvate
mmu_M00549  Nucleotide sugar biosynthesis, glucose => UDP-glucose
mmu_M00892  UDP-N-acetyl-D-glucosamine biosynthesis, eukaryotes, glucose => UDP-GlcNAc
Brite
KEGG Orthology (KO) [BR:mmu00001]
 09100 Metabolism
  09101 Carbohydrate metabolism
   00010 Glycolysis / Gluconeogenesis
    15277 (Hk2)
   00051 Fructose and mannose metabolism
    15277 (Hk2)
   00052 Galactose metabolism
    15277 (Hk2)
   00500 Starch and sucrose metabolism
    15277 (Hk2)
   00520 Amino sugar and nucleotide sugar metabolism
    15277 (Hk2)
  09110 Biosynthesis of other secondary metabolites
   00524 Neomycin, kanamycin and gentamicin biosynthesis
    15277 (Hk2)
 09130 Environmental Information Processing
  09132 Signal transduction
   04066 HIF-1 signaling pathway
    15277 (Hk2)
 09150 Organismal Systems
  09152 Endocrine system
   04910 Insulin signaling pathway
    15277 (Hk2)
  09154 Digestive system
   04973 Carbohydrate digestion and absorption
    15277 (Hk2)
 09160 Human Diseases
  09161 Cancer: overview
   05230 Central carbon metabolism in cancer
    15277 (Hk2)
  09167 Endocrine and metabolic disease
   04930 Type II diabetes mellitus
    15277 (Hk2)
 09180 Brite Hierarchies
  09182 Protein families: genetic information processing
   04131 Membrane trafficking [BR:mmu04131]
    15277 (Hk2)
Enzymes [BR:mmu01000]
 2. Transferases
  2.7  Transferring phosphorus-containing groups
   2.7.1  Phosphotransferases with an alcohol group as acceptor
    2.7.1.1  hexokinase
     15277 (Hk2)
Membrane trafficking [BR:mmu04131]
 Autophagy
  Mitophagy
   Other mitophagy associated  proteins
    15277 (Hk2)
SSDB
Motif
Pfam: Hexokinase_2 Hexokinase_1 FGGY_N
Other DBs
NCBI-GeneID: 15277
NCBI-ProteinID: NP_038848
MGI: 1315197
Ensembl: ENSMUSG00000000628
Vega: OTTMUSG00000035991
UniProt: O08528
Position
6 C3; 6 35.94 cM
AA seq 917 aa
MIASHMIACLFTELNQNQVQKVDQYLYHMRLSDETLLEISRRFRKEMEKGLGATTHPTAA
VKMLPTFVRSTPDGTEHGEFLALDLGGTNFRVLRVRVTDNGLQRVEMENQIYAIPEDIMR
GSGTQLFDHIAECLANFMDKLQIKEKKLPLGFTFSFPCHQTKLDESFLVSWTKGFKSSGV
EGRDVVDLIRKAIQRRGDFDIDIVAVVNDTVGTMMTCGYDDQNCEIGLIVGTGSNACYME
EMRHIDMVEGDEGRMCINMEWGAFGDDGTLNDIRTEFDREIDMGSLNPGKQLFEKMISGM
YMGELVRLILVKMAKAELLFQGKLSPELLTTGSFETKDVSDIEDDKDGIQKAYQILVRLG
LSPLQEDCVATHRICQIVSTRSASLCAATLAAVLWRIKENKGEERLRSTIGVDGSVYKKH
PHFAKRLHKAVRRLVPDCDVRFLRSEDGSGKGAAMVTAVAYRLADQHRARQKTLESLKLS
HEQLLEVKRRMKVEMEQGLSKETHEAAPVKMLPTYVCATPDGTEKGDFLALDLGGTNFRV
LLVRVRNGKRRGVEMHNKIYSIPQEVMHGTGEELFDHIVQCIADFLEYMGMKGVSLPLGF
TFSFPCQQNSLDQSILLKWTKGFKASGCEGEDVVTLLKEAIRRREEFDLDVVAVVNDTVG
TMMTCGYEDPHCEVGLIVGTGSNACYMEEMRNVELVDGEEGRMCVNMEWGAFGDNGCLDD
LRTVFDVAVDELSLNPGKQRFEKMISGMYLGEIVRNILIDFTKRGLLFRGRISERLKTRG
IFETKFLSQIESDCLALLQVRAILRHLGLESTCDDSIIVKEVCTVVARRAAQLCGAGMAA
VVDKIRENRGLDNLKVTVGVDGTLYKLHPHFAKVMHETVRDLAPKCDVSFLESEDGSGKG
AALITAVACRIREAGQR
NT seq 2754 nt   +upstreamnt  +downstreamnt
atgatcgcctcgcatatgatcgcctgcttattcacggagctcaaccaaaaccaagtgcag
aaggttgaccagtatctctaccacatgcgtctctcagatgagacccttctggagatttct
aggcggttccggaaggagatggagaaggggctaggagctaccacacaccctacagcagct
gtgaagatgctgcccacctttgtgaggtcaactccggatgggacagaacatggcgagttc
ctggctctggaccttggaggaaccaacttccgtgtgctccgagtaagggtgacagacaat
ggtctccagagggtggagatggagaaccagatctacgccattcccgaggacatcatgcgg
ggcagtggaacccagctgtttgaccacattgccgaatgcctggccaacttcatggacaag
ctacagatcaaagagaagaagctcccgctgggtttcaccttctcgttcccctgccaccag
acgaaactggatgagagtttcttggtctcatggactaaggggttcaagtccagtggcgtg
gaaggcagagatgtggtggatctgatccggaaggccatccagcgcagaggggactttgac
attgacattgtggctgtggtgaatgacacggttgggaccatgatgacttgtggttatgat
gatcagaactgcgagattggtctcattgtgggtactggcagtaatgcctgctacatggag
gagatgcgtcacattgacatggtggagggcgacgagggacggatgtgcatcaacatggag
tggggggcctttggggacgacggtacactcaatgacatccgaactgagtttgacagagag
atcgacatgggctcactgaaccctgggaagcagctgtttgagaagatgatcagcgggatg
tacatgggggagctggtcagactcatcctggtgaagatggccaaggccgagctgctgttc
caagggaaactcagcccagagctccttaccactggctccttcgagaccaaagatgtctcg
gatattgaagacgataaggacggaattcagaaggcctaccagatcctggtgcgcctgggt
ctgagcccgctgcaggaggactgtgtggccacgcaccgaatctgccagattgtgtccacg
cgctcagccagcctgtgtgcagccaccctggccgcggtgctgtggcggatcaaagagaac
aagggcgaggagcgactccgctccaccatcggcgtggatggctctgtctacaagaaacat
ccccattttgccaagcgtctccataaggcagtgaggaggctggtgcccgattgtgatgtc
cgcttcctccgctctgaggatggcagcggcaagggggcggctatggtgacggcggtggct
taccgtctggctgaccaacaccgggcccgccagaagaccctggagtctctgaagctgagc
catgaacagctgctggaggttaagagaaggatgaaggtggaaatggagcagggtctgagc
aaggagacgcatgaggccgcccctgtgaagatgttgcccacttatgtgtgtgccactcca
gacggtacagagaaaggagacttcctggccttggatcttggaggaacaaacttccgggtc
ctgctggtgcgcgtgcgtaatggcaagcgaaggggcgtagagatgcataacaagatctac
tccatcccacaggaagtcatgcatggcactggagaagagcttttcgaccacattgtccag
tgcatcgcggacttccttgagtacatgggcatgaagggcgtgtccctacctttgggtttc
accttctccttcccttgccagcagaacagcctggaccagagcatcctcctcaagtggaca
aagggattcaaggcatccggctgcgagggtgaagatgtggtcaccttgctgaaggaagcc
attcgccggcgagaggagtttgacctggatgtggtggccgtggtaaatgacacagttggg
actatgatgacttgtggctatgaagaccctcactgtgaagttggcctcattgttggcact
ggaagcaatgcctgctacatggaggagatgcgtaatgtggaactggtggacggagaggag
gggcggatgtgtgtcaacatggagtggggagcgttcggggacaacggctgcctggatgac
ctgcgcacagtgtttgacgtcgctgtggacgagctctctctcaaccctggcaaacagagg
tttgagaagatgatcagcggcatgtacttgggcgagattgtgcgcaacatcctgatcgat
ttcacaaagcgggggctgctcttccgtggccgcatctcagagcgcctcaagacaagggga
atcttcgaaactaagttcctgtctcagatcgagagtgactgcctggccctgctacaggtc
cgagccatcttgcgccacctagggctggagagcacgtgtgacgacagcatcattgtgaag
gaggtgtgcactgtggtcgcccggcgcgcggcccagctctgtggcgcaggcatggccgcc
gtggtggacaagataagagagaaccgtggactggacaacctcaaagtgacggtgggcgtg
gacgggacactgtacaagcttcatcctcactttgccaaagtcatgcatgagacggtgaga
gatctggctccgaaatgtgacgtgtccttcctggaatccgaggacggcagtgggaaggga
gcggctctcatcactgctgtggcctgtcgcatccgggaggccgggcagagatag

KEGG   Mus musculus (mouse): 212032
Entry
212032            CDS       T01002                                 

Gene name
Hk3, HK_III, HK-III
Definition
(RefSeq) hexokinase 3
  KO
K00844  hexokinase [EC:2.7.1.1]
Organism
mmu  Mus musculus (mouse)
Pathway
mmu00010  Glycolysis / Gluconeogenesis
mmu00051  Fructose and mannose metabolism
mmu00052  Galactose metabolism
mmu00500  Starch and sucrose metabolism
mmu00520  Amino sugar and nucleotide sugar metabolism
mmu00524  Neomycin, kanamycin and gentamicin biosynthesis
mmu01100  Metabolic pathways
mmu01200  Carbon metabolism
mmu04066  HIF-1 signaling pathway
mmu04910  Insulin signaling pathway
mmu04930  Type II diabetes mellitus
mmu04973  Carbohydrate digestion and absorption
mmu05230  Central carbon metabolism in cancer
Module
mmu_M00001  Glycolysis (Embden-Meyerhof pathway), glucose => pyruvate
mmu_M00549  Nucleotide sugar biosynthesis, glucose => UDP-glucose
mmu_M00892  UDP-N-acetyl-D-glucosamine biosynthesis, eukaryotes, glucose => UDP-GlcNAc
Brite
KEGG Orthology (KO) [BR:mmu00001]
 09100 Metabolism
  09101 Carbohydrate metabolism
   00010 Glycolysis / Gluconeogenesis
    212032 (Hk3)
   00051 Fructose and mannose metabolism
    212032 (Hk3)
   00052 Galactose metabolism
    212032 (Hk3)
   00500 Starch and sucrose metabolism
    212032 (Hk3)
   00520 Amino sugar and nucleotide sugar metabolism
    212032 (Hk3)
  09110 Biosynthesis of other secondary metabolites
   00524 Neomycin, kanamycin and gentamicin biosynthesis
    212032 (Hk3)
 09130 Environmental Information Processing
  09132 Signal transduction
   04066 HIF-1 signaling pathway
    212032 (Hk3)
 09150 Organismal Systems
  09152 Endocrine system
   04910 Insulin signaling pathway
    212032 (Hk3)
  09154 Digestive system
   04973 Carbohydrate digestion and absorption
    212032 (Hk3)
 09160 Human Diseases
  09161 Cancer: overview
   05230 Central carbon metabolism in cancer
    212032 (Hk3)
  09167 Endocrine and metabolic disease
   04930 Type II diabetes mellitus
    212032 (Hk3)
 09180 Brite Hierarchies
  09182 Protein families: genetic information processing
   04131 Membrane trafficking [BR:mmu04131]
    212032 (Hk3)
Enzymes [BR:mmu01000]
 2. Transferases
  2.7  Transferring phosphorus-containing groups
   2.7.1  Phosphotransferases with an alcohol group as acceptor
    2.7.1.1  hexokinase
     212032 (Hk3)
Membrane trafficking [BR:mmu04131]
 Autophagy
  Mitophagy
   Other mitophagy associated  proteins
    212032 (Hk3)
SSDB
Motif
Pfam: Hexokinase_2 Hexokinase_1 RIX1
Other DBs
NCBI-GeneID: 212032
NCBI-ProteinID: NP_001028417
MGI: 2670962
Ensembl: ENSMUSG00000025877
Vega: OTTMUSG00000032679
UniProt: Q3TRM8
Position
13; 13 B1
AA seq 922 aa
MATIGPSGLHPGERASVCPHEGVPRPSGSLELECLQQFKVTRTQLQQIQASLLCSMEQAL
KGQDSPAPSVRMLPTYVRSTPHGTEQGDFLVLELGATGASLRVLWVTLTGTKECRVEPRS
REFVIPQEVILGAGQQLFDFAARCLSEFLDAYPVENQGLKLGFNFSFPCHQTGLDRSTLI
SWTKGFRCSGVEGQDVVQLLRDAIQRQGTYRIDVVAMVNDTVGTMMGCELGTRPCEVGLI
VDTGTNACYMEEARHVAALDEDRGRTCVSIEWGSFYDEDALGPVLTTFDSALDRESLTPG
AQRFEKMIGGLYLGELVRLVLVHLTQHGVLFDGCASPALLSQGCILLDHVAEMEDTATGT
ARVHTILQDLGLSPRASDAELVQYVCVAVCTRAAQLCAAALAAVLSRLQHSREQQTLQVA
VATGGRVFERHPRFLRILKETVTLLAPNCDVSFIPSVDGGGRGVAMVTAVAARLAAHRRI
LEETLAPFQLTLEQMTVVQAQMREAMIRGLQGEASSLRMLPTYVRATPDGSERGDFLALD
LGGTNFRVLLVRVAEGSVQIINQVYSIPECRAQGSGQKLFDHIVDCIVDFQKRQGLSGQS
LPLGFTFSFPCKQLGLDQGILLNWTKGFNASGCEGQDVVYLLREAIRRRQAVELNVVAIV
NDTVGTMMSCGYDDPRCEMGLIVGTGTNACYMEELRNVASVPGDSGLMCINMEWGAFGDD
GSLGTLSTRFDTSVDQASINPGKQRFEKMISGMYLGEIVRHILLHLTNLGVLFRGQKTQC
LQARDIFKTKFLSEIESDSLALRQVRAILEDLGLTLTSDDALMVLEVCQAVSRRAAQLCG
AGVAAVVEKIRENRGLQELTVSVGVDGTLYKLHPHFSKLVSATVRKLAPQCTVTFLQSED
GSGKGAALVTAVACRLTQMAHV
NT seq 2769 nt   +upstreamnt  +downstreamnt
atggccaccattgggccttctggcctgcatcctggagaaagagcctcagtctgcccacac
gagggcgtgccaaggccctcaggtagcttagaactggaatgcttgcagcaattcaaggtg
accaggacacagttgcagcagatccaagccagtctcctgtgctccatggagcaggcactg
aagggacaggacagtcccgctccttctgtccggatgctgcccacatacgtgaggtccaca
ccacacggcaccgagcaaggggatttcctggtgctggagctgggggccacaggagcatca
ctacgtgtgttgtgggtaacactgacaggcaccaaagaatgccgggtggagcccaggagc
cgggagtttgtgattcctcaagaggtgatcctaggtgctggccagcagctctttgacttt
gctgcccgatgcctctctgaattcctggatgcataccccgtggagaatcagggtctgaag
cttgggttcaatttctcttttccttgtcaccagacaggcttggacaggagcaccctcatt
tcctggacaaaaggttttaggtgcagcggcgtggaaggccaggatgtggtccagttgcta
agagatgccattcagaggcaggggacctacaggattgatgtggtagccatggtgaatgac
acggtgggcaccatgatgggctgtgagctgggcaccaggccgtgtgaagtcgggctgatt
gtagacaccggtaccaacgcgtgctacatggaggaggcgcggcacgtggccgctctggat
gaggaccgcggccgcacctgtgtcagcatcgagtggggctccttctatgacgaagatgct
ctagggccagtactgaccaccttcgactctgccctggaccgcgagtccctgactcctggt
gctcaaaggtttgagaagatgattggaggcctttacctgggtgagctggtgaggctggtt
ctggtccacttgacccagcacggggtcctctttgatggctgcgcctctcctgcgttgctg
agtcaaggctgtatcctcctggaccacgtggctgagatggaggacaccgccactgggaca
gcccgcgtccacaccatcctgcaggacttgggtctgagccctcgggcctcagatgctgaa
ctggtgcaatatgtgtgcgtggctgtgtgcacacgggctgcccagctctgtgcggctgcc
ctggctgcagtcctctcccgcctccagcacagcagggagcagcagacattgcaagtggct
gtggccactggagggcgagtgtttgaacgacaccccaggttcctccgaatcctaaaggag
acggtaacactcctggccccaaactgtgatgtctccttcatcccctctgtggatggtggt
ggccggggtgtggcaatggtgacagctgtggctgcccgcctggctgctcacaggcgcatc
ctggaagagaccctggcaccatttcagctgaccttggagcagatgacagtggtgcaggca
caaatgcgggaagccatgatcagggggcttcaaggagaggcctcctccctccgcatgctg
cccacttacgtccgagcgacgcccgacggcagcgagcgaggtgatttcctggccttggac
ctagggggcaccaacttccgggtcctgttggtacgagtggcggagggcagtgtgcagatc
atcaaccaggtctactccattcctgagtgtagagcccagggctctggacagaagctcttt
gaccatattgtggactgcatcgtggacttccagaagaggcagggccttagtggacagagc
ctacccctgggtttcaccttctctttcccatgcaagcagcttggcctggaccagggcatc
ctcctgaattggactaaggggttcaatgcatcaggctgtgagggccaggatgttgtgtat
ctattacgggaagccattaggcgcagacaggcagtggagctgaatgtggttgccattgtc
aatgacacggtggggaccatgatgtcctgtggctatgatgatccccgttgtgagatgggc
ctcattgtcggaaccggcaccaacgcctgttacatggaagagctccgcaatgtggcaagt
gtgcctggggactcgggcctcatgtgcatcaacatggagtggggtgcctttggggatgat
ggctcactgggcacactcagcacccgctttgacaccagtgtggaccaggcatccatcaat
ccaggcaaacagaggtttgagaaaatgatcagcggtatgtacttgggggagatcgtccgc
catatcctcctgcacttaaccaatctcggagttctcttccgaggccagaagactcaatgc
cttcaggccagggacatcttcaagactaagttcctctctgagatcgaaagtgatagcctg
gccctgcgtcaggtccgagccatcctggaagatctggggctgactctgacatctgatgac
gccttgatggtcctggaagtgtgccaggctgtgtctcgcagggctgcccaactctgtggg
gcaggtgtggctgccgtggtggagaagattcgggagaaccggggcctgcaggagctgaca
gtgtctgtgggagtagatgggacactctacaagctacatcctcacttctccaagctggtg
tcggcaacagtccggaagctagcccctcagtgcaccgtcacctttttgcagtcggaggat
gggtctggcaaaggcgcagctttggttactgctgttgcttgtcgccttacccagatggcc
cacgtctga

KEGG   Mus musculus (mouse): 216019
Entry
216019            CDS       T01002                                 

Gene name
Hkdc1, BC016235
Definition
(RefSeq) hexokinase domain containing 1
  KO
K00844  hexokinase [EC:2.7.1.1]
Organism
mmu  Mus musculus (mouse)
Pathway
mmu00010  Glycolysis / Gluconeogenesis
mmu00051  Fructose and mannose metabolism
mmu00052  Galactose metabolism
mmu00500  Starch and sucrose metabolism
mmu00520  Amino sugar and nucleotide sugar metabolism
mmu00524  Neomycin, kanamycin and gentamicin biosynthesis
mmu01100  Metabolic pathways
mmu01200  Carbon metabolism
mmu04066  HIF-1 signaling pathway
mmu04910  Insulin signaling pathway
mmu04930  Type II diabetes mellitus
mmu04973  Carbohydrate digestion and absorption
mmu05230  Central carbon metabolism in cancer
Module
mmu_M00001  Glycolysis (Embden-Meyerhof pathway), glucose => pyruvate
mmu_M00549  Nucleotide sugar biosynthesis, glucose => UDP-glucose
mmu_M00892  UDP-N-acetyl-D-glucosamine biosynthesis, eukaryotes, glucose => UDP-GlcNAc
Brite
KEGG Orthology (KO) [BR:mmu00001]
 09100 Metabolism
  09101 Carbohydrate metabolism
   00010 Glycolysis / Gluconeogenesis
    216019 (Hkdc1)
   00051 Fructose and mannose metabolism
    216019 (Hkdc1)
   00052 Galactose metabolism
    216019 (Hkdc1)
   00500 Starch and sucrose metabolism
    216019 (Hkdc1)
   00520 Amino sugar and nucleotide sugar metabolism
    216019 (Hkdc1)
  09110 Biosynthesis of other secondary metabolites
   00524 Neomycin, kanamycin and gentamicin biosynthesis
    216019 (Hkdc1)
 09130 Environmental Information Processing
  09132 Signal transduction
   04066 HIF-1 signaling pathway
    216019 (Hkdc1)
 09150 Organismal Systems
  09152 Endocrine system
   04910 Insulin signaling pathway
    216019 (Hkdc1)
  09154 Digestive system
   04973 Carbohydrate digestion and absorption
    216019 (Hkdc1)
 09160 Human Diseases
  09161 Cancer: overview
   05230 Central carbon metabolism in cancer
    216019 (Hkdc1)
  09167 Endocrine and metabolic disease
   04930 Type II diabetes mellitus
    216019 (Hkdc1)
 09180 Brite Hierarchies
  09182 Protein families: genetic information processing
   04131 Membrane trafficking [BR:mmu04131]
    216019 (Hkdc1)
Enzymes [BR:mmu01000]
 2. Transferases
  2.7  Transferring phosphorus-containing groups
   2.7.1  Phosphotransferases with an alcohol group as acceptor
    2.7.1.1  hexokinase
     216019 (Hkdc1)
Membrane trafficking [BR:mmu04131]
 Autophagy
  Mitophagy
   Other mitophagy associated  proteins
    216019 (Hkdc1)
SSDB
Motif
Pfam: Hexokinase_2 Hexokinase_1 VPS13_mid_rpt CSD
Other DBs
NCBI-GeneID: 216019
NCBI-ProteinID: NP_663394
MGI: 2384910
Ensembl: ENSMUSG00000020080
Vega: OTTMUSG00000024651
UniProt: Q91W97
Position
10; 10 B4
AA seq 915 aa
MFAVHLVAFYFTKLKEDQIKKVDRFLYHMRLSDETLVDIMARFQAEMEKGLGKDTNPTAS
VKMLPTFVRAIPDGSENGEFLSLDLGGSKFRVLKVQVSQEGQQNVQMESQFYPMPNEITR
GNGTELFDYVADCLADFMKTKNLTHKKLPLGFTFSFPCRQNKLEEGVLLSWTKKFKARGV
QDTDVVNRLATAMKKHKDLDVDILALVNDTVGTMMTCAYDDPNCEVGVIIGTGTNACYME
DMSNIDLVEGDEGRMCINTEWGAFGDDGALEDIRTEFDRELDLGSLNPGKQLFEKMISGL
YMGELVRLILLKMAKVGLLFGGAKSSALHTKGKIETQHVAAMEMSKEGLANTREILVDLG
LEPSESDCIAVQHVCTIVSFRSANLCAAALATILTRLRENKKLARLRTTVGMDGTLYKTH
PQYPKRLHKVVRRLVPNCDVRFLLSESGSTKGAAMVTAVASRVQAQRKQIDKVLALFQLT
REQLLGVRDKMRAELEYGLKKKTHSLATVKMLPTYVYGMPDGTEKGKFLALDLGGTNFRV
LLVKIRRRSVRMYNKIFAIPLEIMQGTGEELFDHIVQCIADFLDYMGLKGAQLPLGFTFS
FPCRQTCIDKGTLVGWTKGFKATDCEGEDVVDMLREAIKRRNEFDLDIVAIVNDTVGTMM
TCGYEDPRCEIGLIAGTGSNVCYMEEMRNIELVDGDEGRMCVNTEWGGFGDNGCIDDIRT
QYDKEVDEGSLNAGKQRYEKMTSGMYLGEIVRRILIDLTRQGLLFRGQISERLRTRGIFE
TKFLSQIESDRLALLQVRRILQQLGLDSTCEDSIVVKEVCGAVSRRAAQMCGAGMAAIVE
KRREDQGLQHFKVTVGVDGTLYKLHPHFSRILQETVKELAPQCDVTFMLSEDGSGKGAAL
ITAVAKRLQQPRKDI
NT seq 2748 nt   +upstreamnt  +downstreamnt
atgtttgcagtacacttggtggcgttttacttcaccaagctgaaggaggaccagatcaag
aaggtggacaggttcctgtatcacatgcggctctcggatgagaccctggtggacatcatg
gcccgcttccaggccgagatggagaaaggcttggggaaggacaccaaccccactgcctct
gtgaagatgctgcccacattcgtcagggccattccagatggctcagaaaacggggaattc
ctttccctggatctcggaggatccaagtttcgggtcttgaaggtgcaagtctcccaagag
ggccagcaaaatgttcagatggagagccagttctacccaatgcccaatgaaatcacccgt
gggaatggcacggagctttttgactacgtagccgactgcctggcagatttcatgaagacc
aaaaatctgacacataagaagctgcctctgggcttcaccttttcttttccctgcagacag
aataagttggaggagggtgttctgctttcgtggaccaagaagttcaaggcccggggagtt
caggacacagacgtggtgaaccgcctggccactgccatgaagaagcacaaggacctggac
gtggacatcctggctttggttaacgacactgtggggaccatgatgacttgtgcttatgat
gatcccaactgtgaagtcggcgttatcatcggaacaggcaccaacgcgtgttacatggag
gacatgagcaacatcgacctcgtggaaggggacgagggaaggatgtgtatcaacacggag
tggggggcctttggggacgatggggctttggaggacatccgcaccgagtttgacagagag
ctggacctgggctcgctcaaccccgggaagcagctgttcgagaagatgatcagcgggctg
tacatgggggagctggtcaggcttatcttgctgaagatggccaaagttggtctcctgttt
gggggtgcaaaatcctctgctctccatacaaagggcaagatcgaaacacagcacgtggct
gccatggagatgagtaaagaaggcctggccaacactcgagagatcctggtggatttgggc
ctggagccctctgagtcagactgcatcgctgtccagcacgtgtgcaccatcgtctctttt
cgctcagccaatctctgcgcagcggctctggcaaccatcctgactcgactccgagagaac
aagaagctggcccggctccgcaccacagtgggcatggatggaactctctacaaaacacac
cctcagtaccccaaacgcctacacaaggtggtgaggagactggtcccaaactgtgatgtc
cgcttcctcctgtcagagagtggaagcaccaagggggccgccatggtgaccgcagtggcc
tctcgggtacaggcccagcgcaagcagatcgacaaggtgctggctttgttccagttgacc
cgagagcaactcctgggtgtgcgggacaagatgcgggctgaactagagtacgggctgaag
aaaaagacccactctctggctaccgtgaagatgcttcccacctatgtctatgggatgccg
gatggcacagagaaaggaaagttccttgccctggatttggggggaaccaacttccgagtc
ctcctggtaaagatcaggcggaggtctgtgcgcatgtacaacaagatcttcgccatccct
ctggagatcatgcagggcactggggaggagctctttgaccacatcgtacagtgcatcgct
gacttcctggactacatgggcctcaagggcgcccagctgcctttgggcttcaccttctcc
ttcccctgcagacagacatgcatcgacaaggggactctagtagggtggaccaaaggcttc
aaggccaccgactgtgaaggggaggacgtggtggacatgctcagagaagccatcaagagg
agaaacgagtttgacctggacattgttgcaatcgtgaacgacacagtggggaccatgatg
acctgtggctatgaagatcccaggtgtgagattggcttgattgcagggacaggaagcaac
gtgtgctacatggaggaaatgaggaacatcgagctggtggatggggacgaaggccggatg
tgcgtcaacacggagtggggcgggtttggtgacaatggctgcatcgatgacatccgcacc
cagtatgacaaggaggtggatgagggctccctgaacgccggcaagcagagatacgagaaa
atgaccagtggaatgtacctgggggagattgtgaggcggatcctgatcgacctcacccgg
caggggctcctcttccgagggcagatttcagagcgactccggaccaggggcatctttgaa
accaaattcctgtcccagattgaaagtgaccggctggccctcctgcaggtcaggaggatc
ctgcagcagctgggcctggacagcacgtgcgaagacagtattgtggtgaaggaggtgtgt
ggggctgtgtctcggagggccgcccagatgtgtggtgccggcatggctgccatcgtggag
aagaggagagaagaccaaggcctccagcacttcaaggtcaccgtgggcgtggatggcaca
ctgtacaagctgcacccgcacttctcccggatactgcaggagacggtgaaagagctggcc
cctcagtgtgatgtgacatttatgttgtcagaagacggcagcgggaagggagcagctctg
atcacagctgtagccaagaggttacagcagccacggaaggacatctag

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