KEGG   Mus musculus (mouse): 15511
Entry
15511             CDS       T01002                                 

Gene name
Hspa1b, HSP70B1, Hsp70, Hsp70-1, Hsp70.1, hsp, hsp68
Definition
(RefSeq) heat shock protein 1B
  KO
K03283  heat shock 70kDa protein 1/2/6/8
Organism
mmu  Mus musculus (mouse)
Pathway
mmu03040  Spliceosome
mmu04010  MAPK signaling pathway
mmu04141  Protein processing in endoplasmic reticulum
mmu04144  Endocytosis
mmu04213  Longevity regulating pathway - multiple species
mmu04612  Antigen processing and presentation
mmu04915  Estrogen signaling pathway
mmu05020  Prion disease
mmu05134  Legionellosis
mmu05145  Toxoplasmosis
mmu05162  Measles
mmu05417  Lipid and atherosclerosis
Brite
KEGG Orthology (KO) [BR:mmu00001]
 09120 Genetic Information Processing
  09121 Transcription
   03040 Spliceosome
    15511 (Hspa1b)
  09123 Folding, sorting and degradation
   04141 Protein processing in endoplasmic reticulum
    15511 (Hspa1b)
 09130 Environmental Information Processing
  09132 Signal transduction
   04010 MAPK signaling pathway
    15511 (Hspa1b)
 09140 Cellular Processes
  09141 Transport and catabolism
   04144 Endocytosis
    15511 (Hspa1b)
 09150 Organismal Systems
  09151 Immune system
   04612 Antigen processing and presentation
    15511 (Hspa1b)
  09152 Endocrine system
   04915 Estrogen signaling pathway
    15511 (Hspa1b)
  09149 Aging
   04213 Longevity regulating pathway - multiple species
    15511 (Hspa1b)
 09160 Human Diseases
  09172 Infectious disease: viral
   05162 Measles
    15511 (Hspa1b)
  09171 Infectious disease: bacterial
   05134 Legionellosis
    15511 (Hspa1b)
  09174 Infectious disease: parasitic
   05145 Toxoplasmosis
    15511 (Hspa1b)
  09164 Neurodegenerative disease
   05020 Prion disease
    15511 (Hspa1b)
  09166 Cardiovascular disease
   05417 Lipid and atherosclerosis
    15511 (Hspa1b)
 09180 Brite Hierarchies
  09181 Protein families: metabolism
   01009 Protein phosphatases and associated proteins [BR:mmu01009]
    15511 (Hspa1b)
  09182 Protein families: genetic information processing
   03041 Spliceosome [BR:mmu03041]
    15511 (Hspa1b)
   03009 Ribosome biogenesis [BR:mmu03009]
    15511 (Hspa1b)
   03110 Chaperones and folding catalysts [BR:mmu03110]
    15511 (Hspa1b)
   04131 Membrane trafficking [BR:mmu04131]
    15511 (Hspa1b)
   03051 Proteasome [BR:mmu03051]
    15511 (Hspa1b)
   03029 Mitochondrial biogenesis [BR:mmu03029]
    15511 (Hspa1b)
  09183 Protein families: signaling and cellular processes
   04147 Exosome [BR:mmu04147]
    15511 (Hspa1b)
Protein phosphatases and associated proteins [BR:mmu01009]
 Protein serine/threonine phosphatases
  Phosphoprotein phosphatases (PPPs)
   Protein phosphatase-5
    PP5-interacting proteins
     15511 (Hspa1b)
Spliceosome [BR:mmu03041]
 Complex B
  Other components
   Prp19 complex
    15511 (Hspa1b)
 Complex C
   Prp19-CDC5 complex
    15511 (Hspa1b)
Ribosome biogenesis [BR:mmu03009]
 Eukaryotic type
  Pre-60S particles
   Export and cytoplasmic maturation factors
    15511 (Hspa1b)
Chaperones and folding catalysts [BR:mmu03110]
 Heat shock proteins
  HSP70 / DNAK
   15511 (Hspa1b)
Membrane trafficking [BR:mmu04131]
 Endocytosis
  Clathrin-mediated endocytosis
   Other core components
    15511 (Hspa1b)
 Autophagy
  Chaperone mediated autophagy (CMA)
   Chaperones
    15511 (Hspa1b)
Proteasome [BR:mmu03051]
 Eukaryotic proteasome
  Assembling factors
   Other assembling factors
    15511 (Hspa1b)
Mitochondrial biogenesis [BR:mmu03029]
 Mitochondrial protein import machinery
  Endoplasmic reticulum membrane and cytosol
   Other ER-memrane and cytosol factors
    15511 (Hspa1b)
Exosome [BR:mmu04147]
 Exosomal proteins
  Proteins found in most exosomes
   15511 (Hspa1b)
SSDB
Motif
Pfam: HSP70 MreB_Mbl FGGY_C Radial_spoke_3 DDR Hydantoinase_A
Other DBs
NCBI-GeneID: 15511
NCBI-ProteinID: NP_034608
MGI: 99517
Ensembl: ENSMUSG00000090877
Vega: OTTMUSG00000037920
UniProt: P17879
Position
17 B1; 17 18.5 cM
AA seq 642 aa
MAKNTAIGIDLGTTYSCVGVFQHGKVEIIANDQGNRTTPSYVAFTDTERLIGDAAKNQVA
LNPQNTVFDAKRLIGRKFGDAVVQSDMKHWPFQVVNDGDKPKVQVNYKGESRSFFPEEIS
SMVLTKMKEIAEAYLGHPVTNAVITVPAYFNDSQRQATKDAGVIAGLNVLRIINEPTAAA
IAYGLDRTGKGERNVLIFDLGGGTFDVSILTIDDGIFEVKATAGDTHLGGEDFDNRLVSH
FVEEFKRKHKKDISQNKRAVRRLRTACERAKRTLSSSTQASLEIDSLFEGIDFYTSITRA
RFEELCSDLFRGTLEPVEKALRDAKMDKAQIHDLVLVGGSTRIPKVQKLLQDFFNGRDLN
KSINPDEAVAYGAAVQAAILMGDKSENVQDLLLLDVAPLSLGLETAGGVMTALIKRNSTI
PTKQTQTFTTYSDNQPGVLIQVYEGERAMTRDNNLLGRFELSGIPPAPRGVPQIEVTFDI
DANGILNVTATDKSTGKANKITITNDKGRLSKEEIERMVQEAERYKAEDEVQRDRVAAKN
ALESYAFNMKSAVEDEGLKGKLSEADKKKVLDKCQEVISWLDSNTLADKEEFVHKREELE
RVCSPIISGLYQGAGAPGAGGFGAQAPPKGASGSGPTIEEVD
NT seq 1929 nt   +upstreamnt  +downstreamnt
atggccaagaacacggcgatcggcatcgacctgggcaccacctactcgtgcgtgggcgtg
ttccagcacggcaaggtggagatcatcgccaacgaccagggcaaccgcacgacccccagc
tacgtggccttcaccgacaccgagcgcctcatcggggacgccgccaagaaccaggtggcg
ctgaacccgcagaacaccgtgttcgacgcgaagcggctgatcggccgcaagttcggcgat
gcggtggtgcagtccgacatgaagcactggcccttccaggtggtgaacgacggcgacaag
cccaaggtgcaggtgaactacaagggcgagagccggtcgttcttcccggaggagatctcg
tccatggtgctgacgaagatgaaggagatcgctgaggcgtacctgggccacccggtgacc
aacgcggtgatcacggtgcccgcctacttcaacgactctcagcggcaggccaccaaggac
gcgggcgtgatcgccggtctaaacgtgctgcggatcatcaacgagcccacggcggccgcc
atcgcctacgggctggaccggaccggcaagggcgagcgcaacgtgctcatcttcgacctg
gggggcggcacgttcgacgtgtccatcctgacgatcgacgacggcatcttcgaggtgaag
gccacggcgggcgacacgcacctgggaggggaggacttcgacaaccggctggtgagccac
ttcgtggaggagttcaagaggaagcacaagaaggacatcagccagaacaagcgcgcggtg
cggcggctgcgcacggcgtgtgagagggccaagaggacgctgtcgtccagcacccaggcc
agcctggagatcgactctctgttcgagggcatcgacttctacacatccatcacgcgggcg
cggttcgaagagctgtgctcggacctgttccgcggcacgctggagcccgtggagaaggcc
ctgcgcgacgccaagatggacaaggcgcagatccacgacctggtgctggtgggcggctcg
acgcgcatccccaaggtgcagaagctgctgcaggacttcttcaacgggcgcgacctgaac
aagagcatcaacccggacgaggcggtggcctacggggcggcggtgcaggcggccatcctg
atgggggacaagtcggagaacgtgcaggacctgctgctgctggacgtggcgccgctgtcg
ctgggcctggagactgcgggcggcgtgatgacggcgctcatcaagcgcaactccaccatc
cccaccaagcagacgcagaccttcaccacctactcggacaaccagcccggggtgctgatc
caggtgtacgagggcgagagggccatgacgcgcgacaacaacctgctggggcgcttcgag
ctgagcggcatcccgccggcgcccaggggcgtgccgcagatcgaggtgaccttcgacatc
gacgccaacggcatcctgaacgtcacggccaccgacaagagcaccggcaaggccaacaag
atcaccatcaccaacgacaagggccgcctgagcaaggaggagatcgagcgcatggtgcag
gaggccgagcgctacaaggccgaggacgaggtgcagcgcgacagggtggccgccaagaac
gcgctcgagtcctatgccttcaacatgaagagcgccgtggaggacgagggtctcaagggc
aagctcagcgaggctgacaagaagaaggtgctggacaagtgccaggaggtcatctcctgg
ctggactccaacacgctggccgacaaggaggagttcgtgcacaagcgggaggagctggag
cgggtgtgcagccccatcatcagtgggctgtaccagggtgcgggtgctcctggggctggg
ggcttcggggcccaggcgccgccgaaaggagcctctggctcaggacccaccatcgaggag
gtggattag

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