KEGG   Mus musculus (mouse): 15512
Entry
15512             CDS       T01002                                 

Gene name
Hspa2, 70kD, 70kDa, HSP70.2, HSP70A2, Hsp70, Hsp70-2
Definition
(RefSeq) heat shock protein 2
  KO
K03283  heat shock 70kDa protein 1/2/6/8
Organism
mmu  Mus musculus (mouse)
Pathway
mmu03040  Spliceosome
mmu04010  MAPK signaling pathway
mmu04141  Protein processing in endoplasmic reticulum
mmu04144  Endocytosis
mmu04213  Longevity regulating pathway - multiple species
mmu04612  Antigen processing and presentation
mmu04915  Estrogen signaling pathway
mmu05020  Prion disease
mmu05134  Legionellosis
mmu05145  Toxoplasmosis
mmu05162  Measles
mmu05417  Lipid and atherosclerosis
Brite
KEGG Orthology (KO) [BR:mmu00001]
 09120 Genetic Information Processing
  09121 Transcription
   03040 Spliceosome
    15512 (Hspa2)
  09123 Folding, sorting and degradation
   04141 Protein processing in endoplasmic reticulum
    15512 (Hspa2)
 09130 Environmental Information Processing
  09132 Signal transduction
   04010 MAPK signaling pathway
    15512 (Hspa2)
 09140 Cellular Processes
  09141 Transport and catabolism
   04144 Endocytosis
    15512 (Hspa2)
 09150 Organismal Systems
  09151 Immune system
   04612 Antigen processing and presentation
    15512 (Hspa2)
  09152 Endocrine system
   04915 Estrogen signaling pathway
    15512 (Hspa2)
  09149 Aging
   04213 Longevity regulating pathway - multiple species
    15512 (Hspa2)
 09160 Human Diseases
  09172 Infectious disease: viral
   05162 Measles
    15512 (Hspa2)
  09171 Infectious disease: bacterial
   05134 Legionellosis
    15512 (Hspa2)
  09174 Infectious disease: parasitic
   05145 Toxoplasmosis
    15512 (Hspa2)
  09164 Neurodegenerative disease
   05020 Prion disease
    15512 (Hspa2)
  09166 Cardiovascular disease
   05417 Lipid and atherosclerosis
    15512 (Hspa2)
 09180 Brite Hierarchies
  09181 Protein families: metabolism
   01009 Protein phosphatases and associated proteins [BR:mmu01009]
    15512 (Hspa2)
  09182 Protein families: genetic information processing
   03041 Spliceosome [BR:mmu03041]
    15512 (Hspa2)
   03009 Ribosome biogenesis [BR:mmu03009]
    15512 (Hspa2)
   03110 Chaperones and folding catalysts [BR:mmu03110]
    15512 (Hspa2)
   04131 Membrane trafficking [BR:mmu04131]
    15512 (Hspa2)
   03051 Proteasome [BR:mmu03051]
    15512 (Hspa2)
   03029 Mitochondrial biogenesis [BR:mmu03029]
    15512 (Hspa2)
  09183 Protein families: signaling and cellular processes
   04147 Exosome [BR:mmu04147]
    15512 (Hspa2)
Protein phosphatases and associated proteins [BR:mmu01009]
 Protein serine/threonine phosphatases
  Phosphoprotein phosphatases (PPPs)
   Protein phosphatase-5
    PP5-interacting proteins
     15512 (Hspa2)
Spliceosome [BR:mmu03041]
 Complex B
  Other components
   Prp19 complex
    15512 (Hspa2)
 Complex C
   Prp19-CDC5 complex
    15512 (Hspa2)
Ribosome biogenesis [BR:mmu03009]
 Eukaryotic type
  Pre-60S particles
   Export and cytoplasmic maturation factors
    15512 (Hspa2)
Chaperones and folding catalysts [BR:mmu03110]
 Heat shock proteins
  HSP70 / DNAK
   15512 (Hspa2)
Membrane trafficking [BR:mmu04131]
 Endocytosis
  Clathrin-mediated endocytosis
   Other core components
    15512 (Hspa2)
 Autophagy
  Chaperone mediated autophagy (CMA)
   Chaperones
    15512 (Hspa2)
Proteasome [BR:mmu03051]
 Eukaryotic proteasome
  Assembling factors
   Other assembling factors
    15512 (Hspa2)
Mitochondrial biogenesis [BR:mmu03029]
 Mitochondrial protein import machinery
  Endoplasmic reticulum membrane and cytosol
   Other ER-memrane and cytosol factors
    15512 (Hspa2)
Exosome [BR:mmu04147]
 Exosomal proteins
  Proteins found in most exosomes
   15512 (Hspa2)
SSDB
Motif
Pfam: HSP70 MreB_Mbl FGGY_C DUF1464 Hydantoinase_A DDR CRIC_ras_sig
Other DBs
NCBI-GeneID: 15512
NCBI-ProteinID: NP_001002012
MGI: 96243
Ensembl: ENSMUSG00000059970
UniProt: P17156
Position
12 C3; 12 33.73 cM
AA seq 633 aa
MSARGPAIGIDLGTTYSCVGVFQHGKVEIIANDQGNRTTPSYVAFTDTERLIGDAAKNQV
AMNPTNTIFDAKRLIGRKFEDATVQSDMKHWPFRVVSEGGKPKVQVEYKGEMKTFFPEEI
SSMVLTKMKEIAEAYLGGKVQSAVITVPAYFNDSQRQATKDAGTITGLNVLRIINEPTAA
AIAYGLDKKGCAGGEKNVLIFDLGGGTFDVSILTIEDGIFEVKSTAGDTHLGGEDFDNRM
VSHLAEEFKRKHKKDIGPNKRAVRRLRTACERAKRTLSSSTQASIEIDSLYEGVDFYTSI
TRARFEELNADLFRGTLEPVEKALRDAKLDKGQIQEIVLVGGSTRIPKIQKLLQDFFNGK
ELNKSINPDEAVAYGAAVQAAILIGDKSENVQDLLLLDVTPLSLGIETAGGVMTPLIKRN
TTIPTKQTQTFTTYSDNQSSVLVQVYEGERAMTKDNNLLGKFDLTGIPPAPRGVPQIEVT
FDIDANGILNVTAADKSTGKENKITITNDKGRLSKDDIDRMVQEAERYKSEDEANRDRVA
AKNAVESYTYNIKQTVEDEKLRGKISEQDKNKILDKCQEVINWLDRNQMAEKDEYEHKQK
ELERVCNPIISKLYQGGPGGGGSSGGPTIEEVD
NT seq 1902 nt   +upstreamnt  +downstreamnt
atgtctgcccgcggcccggctatcggcatcgacctgggcaccacttactcgtgcgtgggg
gtattccaacatggcaaggtggagatcatcgccaacgaccagggtaaccgcaccaccccc
agctacgtggccttcactgacaccgagcgtctcatcggcgacgccgccaagaaccaagtg
gccatgaaccccacaaacaccatcttcgacgccaagcggctgatcggacggaagttcgag
gacgccacagtgcagtccgatatgaagcactggccgttccgagtggtgagcgaaggtggg
aagcccaaagtgcaggtggaatataaaggggagatgaagaccttcttccctgaggagatt
tcttccatggtcctcactaagatgaaggagatcgccgaagcctacctggggggcaaggtg
cagagcgcagtcatcactgttcctgcctatttcaacgactcgcagcgccaggccaccaag
gatgcgggcaccatcaccggcctcaacgtgttgcgcatcatcaatgagcccacagcagcg
gccatcgcctacggcctggataagaagggctgtgcgggcggcgagaagaacgtgctcatc
tttgacctgggcgggggcaccttcgatgtgtccatcctgaccatcgaggatggcatcttt
gaggtgaagtccacggccggcgatacccacctgggtggcgaagacttcgacaaccgtatg
gtcagccacctggcggaggagttcaagcgcaaacacaagaaggacattgggcccaacaag
cgcgctgtgcgccggctgcgcaccgcctgcgagcgcgctaagcgcaccctgagctcgtcc
acgcaggccagcatagagatcgactcgctctacgagggcgtggatttctacacgtccatc
acccgcgcccgcttcgaggagctcaacgccgatctcttccgagggaccctggagccggtg
gaaaaggcgctgcgcgatgccaagctagacaagggccagatccaggagatagtgctggtg
ggcggctcaacccgcatccctaagatccagaagctcctgcaagatttcttcaacggcaag
gagctgaacaagagcattaatcccgacgaggcggtggcctacggcgccgctgtgcaggcg
gctatcctcatcggcgacaagtcggaaaatgtgcaggatctgctgttactcgacgtgact
ccattgtcgctcggcatcgaaacagctggcggtgtcatgaccccactcatcaagagaaac
accacgatccccaccaagcagacgcagaccttcactacctactcagacaaccagagcagc
gtgctggtgcaagtgtacgagggcgaacgggccatgaccaaggacaataacctcttgggc
aagttcgacctgactgggatccccccagcaccccgtggggtcccccagatcgaggtcacc
tttgacatcgatgccaacggcatccttaacgtcactgctgccgacaagagcaccggtaaa
gaaaataaaatcaccataaccaacgacaagggtcggctgagcaaagacgacattgaccgg
atggtgcaggaggcggagcggtacaaatcggaagatgaagcaaatcgcgatcgcgtggca
gccaaaaatgcggtggagtcctatacctacaacatcaagcagaccgtggaagacgagaaa
ctgaggggcaagattagcgagcaggacaaaaacaagatcctcgacaagtgtcaggaggtg
atcaactggcttgaccgaaaccagatggcagagaaagatgagtacgaacacaagcagaaa
gagcttgagagagtgtgcaaccccatcatcagcaaactttaccaaggcggtccaggcggc
ggcggctcctctggagggcccaccatcgaggaagtggactag

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Ontology (9)   
   KEGG BRITE (9)   
Pathway (12)   
   KEGG PATHWAY (12)   
Genome (1)   
   KEGG GENOME (1)   
Gene (80)   
   KEGG ORTHOLOGY (1)   
   KEGG GENES (1)   
   RefGene (74)   
   NCBI-PROTEINID (1)   
   NCBI-Gene (1)   
   Ensembl (1)   
   OC (1)   
Protein sequence (5)   
   UniProt (1)   
   SWISS-PROT (1)   
   RefSeq(pep) (3)   
DNA sequence (13)   
   RefSeq(nuc) (3)   
   GenBank (5)   
   EMBL (5)   
Protein domain (7)   
   Pfam (7)   
All databases (127)   

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