| Entry |
|
|---|
| Gene name |
Hsp90ab1, 90kDa, AL022974, C81438, Hsp, Hsp84, Hsp84-1, Hsp90, Hspcb
|
|---|
| Definition |
(RefSeq) heat shock protein 90 alpha (cytosolic), class B member 1
|
|---|
| KO |
| K04079 | molecular chaperone HtpG |
|
|---|
| Organism |
|
|---|
| Pathway |
| mmu04141 | Protein processing in endoplasmic reticulum |
| mmu04612 | Antigen processing and presentation |
| mmu04621 | NOD-like receptor signaling pathway |
| mmu04914 | Progesterone-mediated oocyte maturation |
| mmu05418 | Fluid shear stress and atherosclerosis |
|
|---|
| Brite |
KEGG Orthology (KO) [BR:mmu00001]
09120 Genetic Information Processing
09123 Folding, sorting and degradation
04141 Protein processing in endoplasmic reticulum
15516 (Hsp90ab1)
09130 Environmental Information Processing
09132 Signal transduction
04151 PI3K-Akt signaling pathway
15516 (Hsp90ab1)
09140 Cellular Processes
09143 Cell growth and death
04217 Necroptosis
15516 (Hsp90ab1)
09150 Organismal Systems
09151 Immune system
04621 NOD-like receptor signaling pathway
15516 (Hsp90ab1)
04612 Antigen processing and presentation
15516 (Hsp90ab1)
04659 Th17 cell differentiation
15516 (Hsp90ab1)
04657 IL-17 signaling pathway
15516 (Hsp90ab1)
09152 Endocrine system
04915 Estrogen signaling pathway
15516 (Hsp90ab1)
04914 Progesterone-mediated oocyte maturation
15516 (Hsp90ab1)
09160 Human Diseases
09161 Cancer: overview
05200 Pathways in cancer
15516 (Hsp90ab1)
09162 Cancer: specific types
05215 Prostate cancer
15516 (Hsp90ab1)
09171 Infectious disease: bacterial
05132 Salmonella infection
15516 (Hsp90ab1)
09166 Cardiovascular disease
05417 Lipid and atherosclerosis
15516 (Hsp90ab1)
05418 Fluid shear stress and atherosclerosis
15516 (Hsp90ab1)
09180 Brite Hierarchies
09181 Protein families: metabolism
01009 Protein phosphatases and associated proteins [BR:mmu01009]
15516 (Hsp90ab1)
09182 Protein families: genetic information processing
03110 Chaperones and folding catalysts [BR:mmu03110]
15516 (Hsp90ab1)
04131 Membrane trafficking [BR:mmu04131]
15516 (Hsp90ab1)
03051 Proteasome [BR:mmu03051]
15516 (Hsp90ab1)
03029 Mitochondrial biogenesis [BR:mmu03029]
15516 (Hsp90ab1)
09183 Protein families: signaling and cellular processes
04147 Exosome [BR:mmu04147]
15516 (Hsp90ab1)
Protein phosphatases and associated proteins [BR:mmu01009]
Protein serine/threonine phosphatases
Phosphoprotein phosphatases (PPPs)
Protein phosphatase-5
PP5-interacting proteins
15516 (Hsp90ab1)
Chaperones and folding catalysts [BR:mmu03110]
Heat shock proteins
HSP90
15516 (Hsp90ab1)
Membrane trafficking [BR:mmu04131]
Autophagy
Chaperone mediated autophagy (CMA)
Chaperones
15516 (Hsp90ab1)
Proteasome [BR:mmu03051]
Eukaryotic proteasome
Assembling factors
Other assembling factors
15516 (Hsp90ab1)
Mitochondrial biogenesis [BR:mmu03029]
Mitochondrial quality control factors
Mitophagy factors
Parkin-independent mechanism factors
15516 (Hsp90ab1)
Exosome [BR:mmu04147]
Exosomal proteins
Proteins found in most exosomes
15516 (Hsp90ab1)
|
|---|
| SSDB |
|
|---|
| Motif |
|
|---|
| Other DBs |
|
|---|
| Position |
17 B3; 17 22.59 cM
|
|---|
| AA seq |
724 aa
MPEEVHHGEEEVETFAFQAEIAQLMSLIINTFYSNKEIFLRELISNASDALDKIRYESLT
DPSKLDSGKELKIDIIPNPQERTLTLVDTGIGMTKADLINNLGTIAKSGTKAFMEALQAG
ADISMIGQFGVGFYSAYLVAEKVVVITKHNDDEQYAWESSAGGSFTVRADHGEPIGRGTK
VILHLKEDQTEYLEERRVKEVVKKHSQFIGYPITLYLEKEREKEISDDEAEEEKGEKEEE
DKEDEEKPKIEDVGSDEEDDSGKDKKKKTKKIKEKYIDQEELNKTKPIWTRNPDDITQEE
YGEFYKSLTNDWEDHLAVKHFSVEGQLEFRALLFIPRRAPFDLFENKKKKNNIKLYVRRV
FIMDSCDELIPEYLNFIRGVVDSEDLPLNISREMLQQSKILKVIRKNIVKKCLELFSELA
EDKENYKKFYEAFSKNLKLGIHEDSTNRRRLSELLRYHTSQSGDEMTSLSEYVSRMKETQ
KSIYYITGESKEQVANSAFVERVRKRGFEVVYMTEPIDEYCVQQLKEFDGKSLVSVTKEG
LELPEDEEEKKKMEESKAKFENLCKLMKEILDKKVEKVTISNRLVSSPCCIVTSTYGWTA
NMERIMKAQALRDNSTMGYMMAKKHLEINPDHPIVETLRQKAEADKNDKAVKDLVVLLFE
TALLSSGFSLEDPQTHSNRIYRMIKLGLGIDEDEVTAEEPSAAVPDEIPPLEGDEDASRM
EEVD |
|---|
| NT seq |
2175 nt +upstreamnt +downstreamnt
atgcctgaggaagtgcaccatggagaggaggaggtggagacctttgcctttcaggcagaa
attgcccagctcatgtccctcatcatcaacactttctattcaaacaaggagattttcctc
cgcgagttgatctctaatgcttcagatgccctggacaagattcgatatgagagcctgacg
gacccttctaagttggacagtgggaaagagctgaaaattgacatcatccccaaccctcag
gagcgcacgctgactttggtggacacaggcattggcatgaccaaggctgacctcattaat
aacctgggaaccattgctaagtctggcacgaaggcgttcatggaggctctccaggctggt
gcagacatctccatgatcgggcagtttggtgtcggattctactcggcctatctagttgca
gagaaagtggttgtgatcacgaagcacaatgatgatgagcagtatgcctgggagtcgtct
gcgggtggctccttcaccgtccgggcagaccatggtgagcccattggccggggtaccaaa
gtgatccttcacctcaaagaagaccagacagagtacttggaggagaggagggtcaaggaa
gtggtgaagaaacattcgcagttcataggctatcccatcaccctctatttggagaaggaa
cgggagaaggagatcagtgatgatgaggcagaggaagagaaaggtgagaaagaggaggaa
gataaggaggatgaggagaagcctaagattgaagatgtgggatccgatgaggaagatgac
agcggcaaagacaagaaaaagaaaacaaagaagatcaaagagaagtacattgaccaggag
gagctgaacaagacaaagcctatctggaccagaaacccggatgacatcacgcaggaggag
tatggcgaattctataagagcctcaccaatgactgggaggaccacttggcagtcaagcac
ttctctgtagaaggtcagttggaattcagggcattgctcttcattccccggcgggctccc
ttcgacctttttgagaacaagaagaagaagaacaacatcaaattgtatgtccgccgtgtg
ttcatcatggacagctgtgacgagctgatacctgagtacctcaactttatccgcggtgtg
gttgactccgaggacctgcccctgaacatctcccgggagatgctgcagcagagcaagatc
ctgaaggtcatccgcaagaacatcgtcaagaagtgcctggagctcttctccgagctggct
gaggacaaggagaactacaagaagttctatgaggccttctccaaaaatttaaagcttgga
attcatgaagattccactaaccgacgccgcctctctgagctccttcgctatcacacctct
cagtctggagatgagatgacctccttgtcagagtatgtgtctcgcatgaaggagacccag
aagtccatctactatatcactggtgagagcaaagagcaagtggccaactctgcctttgtg
gagcgagtgcggaagcggggcttcgaggtggtgtatatgactgagcctattgacgagtac
tgcgtgcagcagctcaaggagtttgatgggaagagcctggtctcagtgactaaggagggc
ctggagctaccagaggacgaggaagagaagaagaaaatggaggagagcaaggcaaagttt
gagaatctctgcaagctcatgaaggagatcttggacaagaaggttgaaaaggtgacaatc
tccaataggcttgtgtcttcaccctgctgcattgtgacaagcacctatggctggacagcc
aacatggaacggatcatgaaggcccaggcactgcgagacaactctacaatgggctacatg
atggccaaaaaacacctggagatcaaccctgaccaccccatcgtggagaccctgcggcag
aaggctgaggcagacaaaaacgacaaagctgtcaaggacctggtggtgctgctgtttgaa
actgctctgctctcctctggtttctcacttgaggatccccaaacccactccaaccgcatc
taccgcatgattaaactaggcctgggcatcgatgaagatgaggtcactgcagaggagccc
agtgctgctgttcctgatgagatcccccctctggaaggcgatgaggatgcctcgcgcatg
gaagaggtggattaa |
|---|
