| Entry |
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| Gene name |
Hsp90ab1, 90kDa, AL022974, C81438, Hsp, Hsp84, Hsp84-1, Hsp90, Hspcb
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| Definition |
(RefSeq) heat shock protein 90 alpha (cytosolic), class B member 1
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| KO |
| K04079 | molecular chaperone HtpG |
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| Organism |
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| Pathway |
| mmu04141 | Protein processing in endoplasmic reticulum |
| mmu04612 | Antigen processing and presentation |
| mmu04621 | NOD-like receptor signaling pathway |
| mmu04914 | Progesterone-mediated oocyte maturation |
| mmu05418 | Fluid shear stress and atherosclerosis |
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| Brite |
KEGG Orthology (KO) [BR:mmu00001]
09120 Genetic Information Processing
09123 Folding, sorting and degradation
04141 Protein processing in endoplasmic reticulum
15516 (Hsp90ab1)
09130 Environmental Information Processing
09132 Signal transduction
04151 PI3K-Akt signaling pathway
15516 (Hsp90ab1)
09140 Cellular Processes
09143 Cell growth and death
04217 Necroptosis
15516 (Hsp90ab1)
09150 Organismal Systems
09151 Immune system
04621 NOD-like receptor signaling pathway
15516 (Hsp90ab1)
04612 Antigen processing and presentation
15516 (Hsp90ab1)
04659 Th17 cell differentiation
15516 (Hsp90ab1)
04657 IL-17 signaling pathway
15516 (Hsp90ab1)
09152 Endocrine system
04915 Estrogen signaling pathway
15516 (Hsp90ab1)
04914 Progesterone-mediated oocyte maturation
15516 (Hsp90ab1)
09160 Human Diseases
09161 Cancer: overview
05200 Pathways in cancer
15516 (Hsp90ab1)
09162 Cancer: specific types
05215 Prostate cancer
15516 (Hsp90ab1)
09166 Cardiovascular disease
05418 Fluid shear stress and atherosclerosis
15516 (Hsp90ab1)
09171 Infectious disease: bacterial
05132 Salmonella infection
15516 (Hsp90ab1)
Protein phosphatases and associated proteins [BR:mmu01009]
Protein serine/threonine phosphatases
Phosphoprotein phosphatases (PPPs)
Protein phosphatase-5
PP5-interacting proteins
15516 (Hsp90ab1)
Chaperones and folding catalysts [BR:mmu03110]
Heat shock proteins
HSP90
15516 (Hsp90ab1)
Membrane trafficking [BR:mmu04131]
Autophagy
Chaperone mediated autophagy (CMA)
Chaperones
15516 (Hsp90ab1)
Proteasome [BR:mmu03051]
Eukaryotic proteasome
Assembling factors
Other assembling factors
15516 (Hsp90ab1)
Mitochondrial biogenesis [BR:mmu03029]
Mitochondrial quality control factors
Mitophagy factors
Parkin-independent mechanism factors
15516 (Hsp90ab1)
Exosome [BR:mmu04147]
Exosomal proteins
Proteins found in most exosomes
15516 (Hsp90ab1)
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| SSDB |
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| Motif |
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| Other DBs |
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| Position |
17 B3; 17 22.59 cM
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| AA seq |
724 aa
MPEEVHHGEEEVETFAFQAEIAQLMSLIINTFYSNKEIFLRELISNASDALDKIRYESLT
DPSKLDSGKELKIDIIPNPQERTLTLVDTGIGMTKADLINNLGTIAKSGTKAFMEALQAG
ADISMIGQFGVGFYSAYLVAEKVVVITKHNDDEQYAWESSAGGSFTVRADHGEPIGRGTK
VILHLKEDQTEYLEERRVKEVVKKHSQFIGYPITLYLEKEREKEISDDEAEEEKGEKEEE
DKEDEEKPKIEDVGSDEEDDSGKDKKKKTKKIKEKYIDQEELNKTKPIWTRNPDDITQEE
YGEFYKSLTNDWEDHLAVKHFSVEGQLEFRALLFIPRRAPFDLFENKKKKNNIKLYVRRV
FIMDSCDELIPEYLNFIRGVVDSEDLPLNISREMLQQSKILKVIRKNIVKKCLELFSELA
EDKENYKKFYEAFSKNLKLGIHEDSTNRRRLSELLRYHTSQSGDEMTSLSEYVSRMKETQ
KSIYYITGESKEQVANSAFVERVRKRGFEVVYMTEPIDEYCVQQLKEFDGKSLVSVTKEG
LELPEDEEEKKKMEESKAKFENLCKLMKEILDKKVEKVTISNRLVSSPCCIVTSTYGWTA
NMERIMKAQALRDNSTMGYMMAKKHLEINPDHPIVETLRQKAEADKNDKAVKDLVVLLFE
TALLSSGFSLEDPQTHSNRIYRMIKLGLGIDEDEVTAEEPSAAVPDEIPPLEGDEDASRM
EEVD |
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| NT seq |
2175 nt +upstreamnt +downstreamnt
atgcctgaggaagtgcaccatggagaggaggaggtggagacctttgcctttcaggcagaa
attgcccagctcatgtccctcatcatcaacactttctattcaaacaaggagattttcctc
cgcgagttgatctctaatgcttcagatgccctggacaagattcgatatgagagcctgacg
gacccttctaagttggacagtgggaaagagctgaaaattgacatcatccccaaccctcag
gagcgcacgctgactttggtggacacaggcattggcatgaccaaggctgacctcattaat
aacctgggaaccattgctaagtctggcacgaaggcgttcatggaggctctccaggctggt
gcagacatctccatgatcgggcagtttggtgtcggattctactcggcctatctagttgca
gagaaagtggttgtgatcacgaagcacaatgatgatgagcagtatgcctgggagtcgtct
gcgggtggctccttcaccgtccgggcagaccatggtgagcccattggccggggtaccaaa
gtgatccttcacctcaaagaagaccagacagagtacttggaggagaggagggtcaaggaa
gtggtgaagaaacattcgcagttcataggctatcccatcaccctctatttggagaaggaa
cgggagaaggagatcagtgatgatgaggcagaggaagagaaaggtgagaaagaggaggaa
gataaggaggatgaggagaagcctaagattgaagatgtgggatccgatgaggaagatgac
agcggcaaagacaagaaaaagaaaacaaagaagatcaaagagaagtacattgaccaggag
gagctgaacaagacaaagcctatctggaccagaaacccggatgacatcacgcaggaggag
tatggcgaattctataagagcctcaccaatgactgggaggaccacttggcagtcaagcac
ttctctgtagaaggtcagttggaattcagggcattgctcttcattccccggcgggctccc
ttcgacctttttgagaacaagaagaagaagaacaacatcaaattgtatgtccgccgtgtg
ttcatcatggacagctgtgacgagctgatacctgagtacctcaactttatccgcggtgtg
gttgactccgaggacctgcccctgaacatctcccgggagatgctgcagcagagcaagatc
ctgaaggtcatccgcaagaacatcgtcaagaagtgcctggagctcttctccgagctggct
gaggacaaggagaactacaagaagttctatgaggccttctccaaaaatttaaagcttgga
attcatgaagattccactaaccgacgccgcctctctgagctccttcgctatcacacctct
cagtctggagatgagatgacctccttgtcagagtatgtgtctcgcatgaaggagacccag
aagtccatctactatatcactggtgagagcaaagagcaagtggccaactctgcctttgtg
gagcgagtgcggaagcggggcttcgaggtggtgtatatgactgagcctattgacgagtac
tgcgtgcagcagctcaaggagtttgatgggaagagcctggtctcagtgactaaggagggc
ctggagctaccagaggacgaggaagagaagaagaaaatggaggagagcaaggcaaagttt
gagaatctctgcaagctcatgaaggagatcttggacaagaaggttgaaaaggtgacaatc
tccaataggcttgtgtcttcaccctgctgcattgtgacaagcacctatggctggacagcc
aacatggaacggatcatgaaggcccaggcactgcgagacaactctacaatgggctacatg
atggccaaaaaacacctggagatcaaccctgaccaccccatcgtggagaccctgcggcag
aaggctgaggcagacaaaaacgacaaagctgtcaaggacctggtggtgctgctgtttgaa
actgctctgctctcctctggtttctcacttgaggatccccaaacccactccaaccgcatc
taccgcatgattaaactaggcctgggcatcgatgaagatgaggtcactgcagaggagccc
agtgctgctgttcctgatgagatcccccctctggaaggcgatgaggatgcctcgcgcatg
gaagaggtggattaa |
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