KEGG   Mus musculus (mouse): 16151
Entry
16151             CDS       T01002                                 

Gene name
Ikbkg, 1110037D23Rik, AI848108, AI851264, AW124339, IKK[g, IKK[g], NE, NEMO
Definition
(RefSeq) inhibitor of kappaB kinase gamma
  KO
K07210  inhibitor of nuclear factor kappa-B kinase subunit gamma
Organism
mmu  Mus musculus (mouse)
Pathway
mmu01523  Antifolate resistance
mmu04010  MAPK signaling pathway
mmu04014  Ras signaling pathway
mmu04062  Chemokine signaling pathway
mmu04064  NF-kappa B signaling pathway
mmu04151  PI3K-Akt signaling pathway
mmu04210  Apoptosis
mmu04380  Osteoclast differentiation
mmu04620  Toll-like receptor signaling pathway
mmu04621  NOD-like receptor signaling pathway
mmu04622  RIG-I-like receptor signaling pathway
mmu04623  Cytosolic DNA-sensing pathway
mmu04625  C-type lectin receptor signaling pathway
mmu04657  IL-17 signaling pathway
mmu04658  Th1 and Th2 cell differentiation
mmu04659  Th17 cell differentiation
mmu04660  T cell receptor signaling pathway
mmu04662  B cell receptor signaling pathway
mmu04668  TNF signaling pathway
mmu04920  Adipocytokine signaling pathway
mmu05132  Salmonella infection
mmu05135  Yersinia infection
mmu05142  Chagas disease
mmu05145  Toxoplasmosis
mmu05160  Hepatitis C
mmu05161  Hepatitis B
mmu05162  Measles
mmu05163  Human cytomegalovirus infection
mmu05164  Influenza A
mmu05165  Human papillomavirus infection
mmu05166  Human T-cell leukemia virus 1 infection
mmu05167  Kaposi sarcoma-associated herpesvirus infection
mmu05168  Herpes simplex virus 1 infection
mmu05169  Epstein-Barr virus infection
mmu05170  Human immunodeficiency virus 1 infection
mmu05171  Coronavirus disease - COVID-19
mmu05200  Pathways in cancer
mmu05203  Viral carcinogenesis
mmu05212  Pancreatic cancer
mmu05215  Prostate cancer
mmu05220  Chronic myeloid leukemia
mmu05221  Acute myeloid leukemia
mmu05222  Small cell lung cancer
mmu05235  PD-L1 expression and PD-1 checkpoint pathway in cancer
mmu05340  Primary immunodeficiency
mmu05418  Fluid shear stress and atherosclerosis
Brite
KEGG Orthology (KO) [BR:mmu00001]
 09130 Environmental Information Processing
  09132 Signal transduction
   04010 MAPK signaling pathway
    16151 (Ikbkg)
   04014 Ras signaling pathway
    16151 (Ikbkg)
   04064 NF-kappa B signaling pathway
    16151 (Ikbkg)
   04668 TNF signaling pathway
    16151 (Ikbkg)
   04151 PI3K-Akt signaling pathway
    16151 (Ikbkg)
 09140 Cellular Processes
  09143 Cell growth and death
   04210 Apoptosis
    16151 (Ikbkg)
 09150 Organismal Systems
  09151 Immune system
   04620 Toll-like receptor signaling pathway
    16151 (Ikbkg)
   04621 NOD-like receptor signaling pathway
    16151 (Ikbkg)
   04622 RIG-I-like receptor signaling pathway
    16151 (Ikbkg)
   04623 Cytosolic DNA-sensing pathway
    16151 (Ikbkg)
   04625 C-type lectin receptor signaling pathway
    16151 (Ikbkg)
   04660 T cell receptor signaling pathway
    16151 (Ikbkg)
   04658 Th1 and Th2 cell differentiation
    16151 (Ikbkg)
   04659 Th17 cell differentiation
    16151 (Ikbkg)
   04657 IL-17 signaling pathway
    16151 (Ikbkg)
   04662 B cell receptor signaling pathway
    16151 (Ikbkg)
   04062 Chemokine signaling pathway
    16151 (Ikbkg)
  09152 Endocrine system
   04920 Adipocytokine signaling pathway
    16151 (Ikbkg)
  09158 Development and regeneration
   04380 Osteoclast differentiation
    16151 (Ikbkg)
 09160 Human Diseases
  09161 Cancer: overview
   05200 Pathways in cancer
    16151 (Ikbkg)
   05203 Viral carcinogenesis
    16151 (Ikbkg)
   05235 PD-L1 expression and PD-1 checkpoint pathway in cancer
    16151 (Ikbkg)
  09162 Cancer: specific types
   05212 Pancreatic cancer
    16151 (Ikbkg)
   05221 Acute myeloid leukemia
    16151 (Ikbkg)
   05220 Chronic myeloid leukemia
    16151 (Ikbkg)
   05215 Prostate cancer
    16151 (Ikbkg)
   05222 Small cell lung cancer
    16151 (Ikbkg)
  09172 Infectious disease: viral
   05166 Human T-cell leukemia virus 1 infection
    16151 (Ikbkg)
   05170 Human immunodeficiency virus 1 infection
    16151 (Ikbkg)
   05161 Hepatitis B
    16151 (Ikbkg)
   05160 Hepatitis C
    16151 (Ikbkg)
   05171 Coronavirus disease - COVID-19
    16151 (Ikbkg)
   05164 Influenza A
    16151 (Ikbkg)
   05162 Measles
    16151 (Ikbkg)
   05168 Herpes simplex virus 1 infection
    16151 (Ikbkg)
   05163 Human cytomegalovirus infection
    16151 (Ikbkg)
   05167 Kaposi sarcoma-associated herpesvirus infection
    16151 (Ikbkg)
   05169 Epstein-Barr virus infection
    16151 (Ikbkg)
   05165 Human papillomavirus infection
    16151 (Ikbkg)
  09171 Infectious disease: bacterial
   05132 Salmonella infection
    16151 (Ikbkg)
   05135 Yersinia infection
    16151 (Ikbkg)
  09174 Infectious disease: parasitic
   05145 Toxoplasmosis
    16151 (Ikbkg)
   05142 Chagas disease
    16151 (Ikbkg)
  09163 Immune disease
   05340 Primary immunodeficiency
    16151 (Ikbkg)
  09166 Cardiovascular disease
   05418 Fluid shear stress and atherosclerosis
    16151 (Ikbkg)
  09176 Drug resistance: antineoplastic
   01523 Antifolate resistance
    16151 (Ikbkg)
 09180 Brite Hierarchies
  09181 Protein families: metabolism
   01001 Protein kinases [BR:mmu01001]
    16151 (Ikbkg)
Protein kinases [BR:mmu01001]
 Serine/threonine kinases: Other
  IKK family [OT]
   16151 (Ikbkg)
SSDB
Motif
Pfam: NEMO CC2-LZ zf_C2H2_10 ERM
Other DBs
NCBI-GeneID: 16151
NCBI-ProteinID: NP_001154895
MGI: 1338074
Ensembl: ENSMUSG00000004221
Vega: OTTMUSG00000017732
UniProt: O88522 Q8VC91
Structure
PDB: 

Position
X; X A7.3
AA seq 412 aa
MNKHPWKNQLSEMVQPSGGPAEDQDMLGEESSLGKPAMLHLPSEQGTPETLQRCLEENQE
LRDAIRQSNQMLRERCEELLHFQVSQREEKEFLMCKFQEARKLVERLSLEKLDLRSQREQ
ALKELEQLKKCQQQMAEDKASVKAQVTSLLGELQESQSRLEAATKDRQALEGRIRAVSEQ
VRQLESEREVLQQQHSVQVDQLRMQNQSVEAALRMERQAASEEKRKLAQLQAAYHQLFQD
YDSHIKSSKGMQLEDLRQQLQQAEEALVAKQELIDKLKEEAEQHKIVMETVPVLKAQADI
YKADFQAERHAREKLVEKKEYLQEQLEQLQREFNKLKVGCHESARIEDMRKRHVETPQPP
LLPAPAHHSFHLALSNQRRSPPEEPPDFCCPKCQYQAPDMDTLQIHVMECIE
NT seq 1239 nt   +upstreamnt  +downstreamnt
atgaacaagcacccctggaagaaccagctgagtgagatggtgcagcccagtggtggccca
gcagaggaccaggacatgctgggtgaagaatcttctctggggaagcctgcaatgctacat
ctgccttcagagcagggtactcctgagaccctccagcgctgcctggaagagaatcaagag
ctccgagacgctatccggcagagcaatcagatgctgagggaacgctgtgaggagctgctg
catttccaggtcagccagcgggaggagaaggagttccttatgtgcaaattccaggaagcc
cggaagctggtggagagactgagcttggagaagcttgatcttcggagtcagagggaacag
gccttaaaggagttggagcaactgaagaaatgccaacagcagatggctgaggacaaggcc
tctgtgaaagctcaggtgacatcattgctcggagaactccaggagagccagagccgtttg
gaggctgccaccaaggatcggcaagctttagagggaaggattcgagcagttagtgagcag
gtcagacagctggagagtgagcgggaggtgctacagcagcagcacagcgtccaggtggac
cagctgcgtatgcagaaccagagcgtggaggctgccttgcgaatggagcggcaggctgct
tcagaggagaagcggaagctggctcagttgcaggcagcctatcaccagctcttccaagac
tacgacagccacattaagagcagcaagggcatgcagctggaagatctgaggcaacagctc
cagcaagctgaggaggccctggtagccaaacaggaattgattgataagctgaaagaggag
gctgagcagcacaagattgtgatggagactgtgccagtcttgaaggcccaggcggatatc
tacaaggctgacttccaagctgagaggcatgcccgggagaagctggtggagaagaaggag
tatttgcaggagcagctggagcagctgcagcgcgagttcaacaagctgaaagttggctgc
catgagtcagccaggattgaggatatgaggaagcggcatgtagagactccccagcctcct
ttactccctgctccagctcaccactcctttcatttggccttgtccaaccagcggaggagc
cctcctgaagaacctcctgacttctgttgtccgaagtgccagtatcaggctcctgatatg
gacactctacagatacatgtcatggagtgcatagagtag

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Ontology (2)   
   KEGG BRITE (2)   
Pathway (46)   
   KEGG PATHWAY (46)   
Genome (1)   
   KEGG GENOME (1)   
Gene (19)   
   KEGG ORTHOLOGY (1)   
   KEGG GENES (1)   
   RefGene (12)   
   NCBI-PROTEINID (1)   
   NCBI-Gene (1)   
   Ensembl (1)   
   OC (1)   
   VEGA (1)   
Protein sequence (18)   
   UniProt (2)   
   SWISS-PROT (1)   
   RefSeq(pep) (15)   
DNA sequence (49)   
   RefSeq(nuc) (15)   
   GenBank (17)   
   EMBL (17)   
Protein domain (4)   
   Pfam (4)   
All databases (139)   

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