KEGG   Mus musculus (mouse): 16331Help
Entry
16331             CDS       T01002                                 

Gene name
Inpp5d, SHIP, SHIP-1, SHIP1, SIP-145, p150Ship, s-SHIP
Definition
(RefSeq) inositol polyphosphate-5-phosphatase D
  KO
K03084  phosphatidylinositol-3,4,5-trisphosphate 5-phosphatase 1 [EC:3.1.3.86]
Organism
mmu  Mus musculus (mouse)
Pathway
mmu00562  Inositol phosphate metabolism
mmu01100  Metabolic pathways
mmu04070  Phosphatidylinositol signaling system
mmu04662  B cell receptor signaling pathway
mmu04664  Fc epsilon RI signaling pathway
mmu04666  Fc gamma R-mediated phagocytosis
Brite
KEGG Orthology (KO) [BR:mmu00001]
 09100 Metabolism
  09101 Carbohydrate metabolism
   00562 Inositol phosphate metabolism
    16331 (Inpp5d)
 09130 Environmental Information Processing
  09132 Signal transduction
   04070 Phosphatidylinositol signaling system
    16331 (Inpp5d)
 09150 Organismal Systems
  09151 Immune system
   04662 B cell receptor signaling pathway
    16331 (Inpp5d)
   04664 Fc epsilon RI signaling pathway
    16331 (Inpp5d)
   04666 Fc gamma R-mediated phagocytosis
    16331 (Inpp5d)
 09180 Brite Hierarchies
  09182 Protein families: genetic information processing
   04131 Membrane trafficking [BR:mmu04131]
    16331 (Inpp5d)
Enzymes [BR:mmu01000]
 3. Hydrolases
  3.1  Acting on ester bonds
   3.1.3  Phosphoric-monoester hydrolases
    3.1.3.86  phosphatidylinositol-3,4,5-trisphosphate 5-phosphatase
     16331 (Inpp5d)
Membrane trafficking [BR:mmu04131]
 Endocytosis
  Rab GTPases and associated proteins
   Rab associated proteins
    16331 (Inpp5d)
BRITE hierarchy
SSDB OrthologParalogGFIT
Motif
Pfam: SH2 Exo_endo_phos
Motif
Other DBs
NCBI-GeneID: 16331
NCBI-ProteinID: NP_034696
MGI: 107357
Ensembl: ENSMUSG00000026288
Vega: OTTMUSG00000035865
UniProt: Q9ES52
Structure
PDB: 

Position
1 D; 1 44.44 cM
AA seq 1191 aa AA seqDB search
MPAMVPGWNHGNITRSKAEELLSRAGKDGSFLVRASESIPRAYALCVLFRNCVYTYRILP
NEDDKFTVQASEGVPMRFFTKLDQLIDFYKKENMGLVTHLQYPVPLEEEDAIDEAEEDTV
ESVMSPPELPPRNIPMSAGPSEAKDLPLATENPRAPEVTRLSLSETLFQRLQSMDTSGLP
EEHLKAIQDYLSTQLLLDSDFLKTGSSNLPHLKKLMSLLCKELHGEVIRTLPSLESLQRL
FDQQLSPGLRPRPQVPGEASPITMVAKLSQLTSLLSSIEDKVKSLLHEGSESTNRRSLIP
PVTFEVKSESLGIPQKMHLKVDVESGKLIVKKSKDGSEDKFYSHKKILQLIKSQKFLNKL
VILVETEKEKILRKEYVFADSKKREGFCQLLQQMKNKHSEQPEPDMITIFIGTWNMGNAP
PPKKITSWFLSKGQGKTRDDSADYIPHDIYVIGTQEDPLGEKEWLELLRHSLQEVTSMTF
KTVAIHTLWNIRIVVLAKPEHENRISHICTDNVKTGIANTLGNKGAVGVSFMFNGTSLGF
VNSHLTSGSEKKLRRNQNYMNILRFLALGDKKLSPFNITHRFTHLFWLGDLNYRVELPTW
EAEAIIQKIKQQQYSDLLAHDQLLLERKDQKVFLHFEEEEITFAPTYRFERLTRDKYAYT
KQKATGMKYNLPSWCDRVLWKSYPLVHVVCQSYGSTSDIMTSDHSPVFATFEAGVTSQFV
SKNGPGTVDSQGQIEFLACYATLKTKSQTKFYLEFHSSCLESFVKSQEGENEEGSEGELV
VRFGETLPKLKPIISDPEYLLDQHILISIKSSDSDESYGEGCIALRLETTEAQHPIYTPL
THHGEMTGHFRGEIKLQTSQGKMREKLYDFVKTERDESSGMKCLKNLTSHDPMRQWEPSG
RVPACGVSSLNEMINPNYIGMGPFGQPLHGKSTLSPDQQLTAWSYDQLPKDSSLGPGRGE
GPPTPPSQPPLSPKKFSSSTANRGPCPRVQEARPGDLGKVEALLQEDLLLTKPEMFENPL
YGSVSSFPKLVPRKEQESPKMLRKEPPPCPDPGISSPSIVLPKAQEVESVKGTSKQAPVP
VLGPTPRIRSFTCSSSAEGRMTSGDKSQGKPKASASSQAPVPVKRPVKPSRSEMSQQTTP
IPAPRPPLPVKSPAVLQLQHSKGRDYRDNTELPHHGKHRQEEGLLGRTAMQ
NT seq 3576 nt NT seq  +upstreamnt  +downstreamnt
atgcctgccatggtccctgggtggaaccatggcaacatcacccgctccaaggcagaggag
ctactttccagagccggcaaggacgggagcttccttgtgcgtgccagcgagtccatcccc
cgggcctacgcactctgcgtgctgttccggaattgtgtttacacttacaggattctgccc
aatgaggacgataaattcactgttcaggcatccgaaggtgtccccatgaggttcttcacg
aagctggaccagctcatcgacttttacaagaaggaaaacatggggctggtgacccacctg
cagtaccccgtgcccctggaggaggaggatgctattgatgaggctgaggaggacactgta
gaaagtgtcatgtcaccacctgagctgcctcccagaaacattcctatgtctgccgggccc
agcgaggccaaggaccttcctcttgcaacagagaacccccgagcccctgaggtcacccgg
ctgagtctctccgagacactgtttcagcgtctacagagcatggataccagtgggcttccc
gaggagcacctgaaagccatccaggattatctgagcactcagctcctcctggattccgac
tttttgaagacgggctccagcaacctccctcacctgaagaagctgatgtcactgctctgc
aaggagctccatggggaagtcatcaggactctgccatccctggagtctctgcagaggttg
tttgaccaacagctctccccaggccttcgcccacgacctcaggtgcccggagaggccagt
cccatcaccatggttgccaaactcagccaattgacaagtctgctgtcttccattgaagat
aaggtcaagtccttgctgcacgagggctcagaatctaccaacaggcgttcccttatccct
ccggtcacctttgaggtgaagtcagagtccctgggcattcctcagaaaatgcatctcaaa
gtggacgttgagtctgggaaactgatcgttaagaagtccaaggatggttctgaggacaag
ttctacagccacaaaaaaatcctgcagctcattaagtcccagaagtttctaaacaagttg
gtgattttggtggagacggagaaggagaaaatcctgaggaaggaatatgtttttgctgac
tctaagaaaagagaaggcttctgtcaactcctgcagcagatgaagaacaagcattcggag
cagccagagcctgacatgatcaccatcttcattggcacttggaacatgggtaatgcaccc
cctcccaagaagatcacgtcctggtttctctccaaggggcagggaaagacacgggacgac
tctgctgactacatcccccatgacatctatgtgattggcacccaggaggatccccttgga
gagaaggagtggctggagctactcaggcactccctgcaagaagtcaccagcatgacattt
aaaacagttgccatccacaccctctggaacattcgcatagtggtgcttgccaagccagag
catgagaatcggatcagccatatctgcactgacaacgtgaagacaggcatcgccaacacc
ctgggaaacaagggagcagtgggagtgtccttcatgttcaatggaacctccttggggttc
gtcaacagccacttgacttctggaagtgaaaaaaagctcaggagaaatcaaaactatatg
aacatcctgcggttcctggccctgggagacaagaagctaagcccatttaacatcacccac
cgcttcacccacctcttctggcttggggatctcaactaccgcgtggagctgcccacttgg
gaggcagaggccatcatccagaagatcaagcaacagcagtattcagaccttctggcccac
gaccaactgctcctggagaggaaggaccagaaggtcttcctgcactttgaggaggaagag
atcaccttcgcccccacctatcgatttgaaagactgacccgggacaagtatgcatacacg
aagcagaaagcaacagggatgaagtacaacttgccgtcctggtgcgaccgagtcctctgg
aagtcttacccgctggtgcatgtggtctgtcagtcctatggcagtaccagtgacatcatg
acgagtgaccacagccctgtctttgccacgtttgaagcaggagtcacatctcaattcgtc
tccaagaatggtcctggcactgtagatagccaagggcagatcgagtttcttgcatgctac
gccacactgaagaccaagtcccagactaagttctacttggagttccactcaagctgctta
gagagttttgtcaagagtcaggaaggagagaatgaagagggaagtgaaggagagctggtg
gtacggtttggagagactcttcccaagctaaagcccattatctctgaccccgagtactta
ctggaccagcatatcctgatcagcattaaatcctctgacagtgacgagtcctatggtgaa
ggctgcattgcccttcgcttggagaccacagaggctcagcatcctatctacacgcctctc
acccaccatggggagatgactggccacttcaggggagagattaagctgcagacctcccag
ggcaagatgagggagaagctctatgactttgtgaagacagagcgggatgaatccagtgga
atgaaatgcttgaagaacctcaccagccatgaccctatgaggcaatgggagccttctggc
agggtccctgcatgtggtgtctccagcctcaatgagatgatcaatccaaactacattggt
atggggccttttggacagcccctgcatgggaaatcaaccctgtccccagatcagcaactc
acagcttggagttatgaccagctacccaaagactcctccctggggcctgggaggggggag
ggtcctccaacccctccctcccaaccacctctgtcgccaaagaagttttcatcttccaca
gccaaccgaggtccctgccccagggtgcaagaggcaagacctggggatctgggaaaggtg
gaagctctgctccaggaggacctgctgctgacgaagcccgagatgtttgagaacccactg
tatggatccgtgagttccttccctaagctggtgcccaggaaagagcaggagtctcccaag
atgctgcggaaggagcccccgccctgtccagacccaggaatctcatcacccagcatcgtg
ctccccaaagcccaagaggtggagagtgtcaaggggacaagcaaacaggcccctgtgcct
gtccttggccccacaccccggatccgctcctttacctgttcttcttctgctgagggcaga
atgaccagtggggacaagagccaagggaagcccaaggcctcagccagttcccaagcccca
gtgccagtcaagaggcctgtcaagccttccaggtcagaaatgagccagcagacaacaccc
atcccagctccacggccacccctgccagtcaagagtcctgctgtcctgcagctgcaacat
tccaaaggcagagactaccgtgacaacacagaactcccccaccatggcaagcaccgccaa
gaggaggggctgcttggcaggactgccatgcagtga

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