KEGG   Mus musculus (mouse): 16409
Entry
16409             CDS       T01002                                 

Gene name
Itgam, CD11b/CD18, CR, CR3, CR3A, Cd11b, F730045J24Rik, Ly-4, Ly-40, MAC1, Mac-, Mac-1, Mac-1a
Definition
(RefSeq) integrin alpha M
  KO
K06461  integrin alpha M
Organism
mmu  Mus musculus (mouse)
Pathway
mmu04015  Rap1 signaling pathway
mmu04145  Phagosome
mmu04514  Cell adhesion molecules
mmu04610  Complement and coagulation cascades
mmu04613  Neutrophil extracellular trap formation
mmu04640  Hematopoietic cell lineage
mmu04670  Leukocyte transendothelial migration
mmu04810  Regulation of actin cytoskeleton
mmu05133  Pertussis
mmu05134  Legionellosis
mmu05140  Leishmaniasis
mmu05146  Amoebiasis
mmu05150  Staphylococcus aureus infection
mmu05152  Tuberculosis
mmu05202  Transcriptional misregulation in cancer
mmu05221  Acute myeloid leukemia
Brite
KEGG Orthology (KO) [BR:mmu00001]
 09130 Environmental Information Processing
  09132 Signal transduction
   04015 Rap1 signaling pathway
    16409 (Itgam)
  09133 Signaling molecules and interaction
   04514 Cell adhesion molecules
    16409 (Itgam)
 09140 Cellular Processes
  09141 Transport and catabolism
   04145 Phagosome
    16409 (Itgam)
  09142 Cell motility
   04810 Regulation of actin cytoskeleton
    16409 (Itgam)
 09150 Organismal Systems
  09151 Immune system
   04640 Hematopoietic cell lineage
    16409 (Itgam)
   04610 Complement and coagulation cascades
    16409 (Itgam)
   04613 Neutrophil extracellular trap formation
    16409 (Itgam)
   04670 Leukocyte transendothelial migration
    16409 (Itgam)
 09160 Human Diseases
  09161 Cancer: overview
   05202 Transcriptional misregulation in cancer
    16409 (Itgam)
  09162 Cancer: specific types
   05221 Acute myeloid leukemia
    16409 (Itgam)
  09171 Infectious disease: bacterial
   05133 Pertussis
    16409 (Itgam)
   05134 Legionellosis
    16409 (Itgam)
   05150 Staphylococcus aureus infection
    16409 (Itgam)
   05152 Tuberculosis
    16409 (Itgam)
  09174 Infectious disease: parasitic
   05146 Amoebiasis
    16409 (Itgam)
   05140 Leishmaniasis
    16409 (Itgam)
 09180 Brite Hierarchies
  09182 Protein families: genetic information processing
   04131 Membrane trafficking [BR:mmu04131]
    16409 (Itgam)
  09183 Protein families: signaling and cellular processes
   04147 Exosome [BR:mmu04147]
    16409 (Itgam)
   04515 Cell adhesion molecules [BR:mmu04515]
    16409 (Itgam)
   04090 CD molecules [BR:mmu04090]
    16409 (Itgam)
   00536 Glycosaminoglycan binding proteins [BR:mmu00536]
    16409 (Itgam)
Membrane trafficking [BR:mmu04131]
 Endocytosis
  Phagocytosis
   Integrins (complement receptors)
    16409 (Itgam)
Exosome [BR:mmu04147]
 Exosomal proteins
  Exosomal proteins of haemopoietic cells  (B-cell, T-cell, DC-cell, reticulocyte, and mast cell)
   16409 (Itgam)
Cell adhesion molecules [BR:mmu04515]
 Integrins
  Integrin alpha subunits
   16409 (Itgam)
CD molecules [BR:mmu04090]
 Proteins
  16409 (Itgam)
Glycosaminoglycan binding proteins [BR:mmu00536]
 Heparan sulfate / Heparin
  Adhesion molecules of cell surface
   16409 (Itgam)
SSDB
Motif
Pfam: VWA Integrin_alpha2 FG-GAP VWA_2 FG-GAP_3 Integrin_alpha FG-GAP_2 AbfS_sensor
Other DBs
NCBI-GeneID: 16409
NCBI-ProteinID: NP_001076429
MGI: 96607
Ensembl: ENSMUSG00000030786
Vega: OTTMUSG00000058643
UniProt: G5E8F1
Position
7; 7 F3
AA seq 1154 aa
MTLKALLVTALALCHGFNLDTEHPMTFQENAKGFGQSVVQLGGTSVVVAAPQEAKAVNQT
GALYQCDYSTSRCHPIPLQVPPEAVNMSLGLSLAVSTVPQQLLACGPTVHQNCKENTYVN
GLCYLFGSNLLRPPQQFPEALRECPQQESDIVFLIDGSGSINNIDFQKMKEFVSTVMEQF
KKSKTLFSLMQYSDEFRIHFTFNDFKRNPSPRSHVSPIKQLNGRTKTASGIRKVVRELFH
KTNGARENAAKILVVITDGEKFGDPLDYKDVIPEADRAGVIRYVIGVGNAFNKPQSRREL
DTIASKPAGEHVFQVDNFEALNTIQNQLQEKIFAIEGTQTGSTSSFEHEMSQEGFSASIT
SNGPLLGSVGSFDWAGGAFLYTSKDKVTFINTTRVDSDMNDAYLGYASAVILRNRVQSLV
LGAPRYQHIGLVVMFRENFGTWEPHTSIKGSQIGSYFGASLCSVDMDADGNTNLILIGAP
HYYEKTRGGQVSVCPLPRGQRARWQCEALLHGDQGHPWGRFGAALTVLGDVNGDKLTDVA
IGAPGEQENQGAVYIFYGASIASLSASHSQRIIGAHFSPGLQYFGQSLSGGKDLTMDGLM
DLAVGAQGHLLLLRAQPVLRLEATMEFSPKKVARSVFACQEQVLKNKDAGEVRVCLRVRK
NTKDRLREGDIQSTVTYDLALDPGRSRIRAFFDETKNNTRRRTQVFGLMQKCETLKLILP
DCVDDSVSPIILRLNYTLVGEPLRSFGNLRPVLAMDAQRFFTAMFPFEKNCGNDSICQDD
LSITMSAMGLDTLVVGGPQDFNMSVTLRNDGEDSYGTQVTVYYPSGLSYRKDSASQNPLT
KKPWFVKPAESSSSSEGHGALKSTTWNINHPIFPANSEVTFNVTFDVDSHASFGNKLLLK
AIVASENNMSRTHKTKFQLELPVKYAIYMIVTSDESSIRYLNFTASEMTSKVIQHQYQFN
NLGQRSLPVSVVFWIPVQINNVTVWDHPQVIFSQNLSSACHTEQKSPPHSNFRDQLERTP
VLNCSVAVCKRIQCDLPSFNTQEIFNVTLKGNLSFDWYIKTSHGHLLLVSSTEILFNDSA
FALLPGQESYVRSKTETKVEPYEVHNPVPLIVGSSIGGLVLLALITAGLYKLGFFKRQYK
DMMNEAAPQDAPPQ
NT seq 3465 nt   +upstreamnt  +downstreamnt
atgactcttaaagctcttctggtcacagccctagccttgtgtcatggcttcaatctggac
actgaacatcccatgaccttccaagagaatgcaaaaggctttggacagagtgtggtccag
cttggcggaaccagtgtggttgttgcagccccccaggaggcaaaggctgttaaccagaca
ggtgccctctaccagtgtgactacagcacaagccggtgtcaccccatccccctgcaagta
cctccagaggctgtgaatatgtccttgggcctgtccctggctgtttctactgtcccccag
cagctgctggcctgtggccccacggtgcaccaaaactgcaaggagaatacttatgtgaat
ggattgtgctatttgttcggctccaacctgctgaggccgccccagcagttcccagaggct
ctcagagaatgtcctcagcaggagagtgacattgtcttcttgattgatggctccggtagc
atcaacaacattgactttcagaagatgaaggagtttgtctcaactgtgatggagcagttc
aaaaagtctaaaaccttgttctctttgatgcagtactcggacgagttccggattcacttc
accttcaatgacttcaagagaaaccctagcccaagatcacatgtgagccccataaagcag
ctgaatgggaggacaaaaactgcctcagggatccggaaagtagtgagagaactgtttcac
aaaaccaatggggcccgggagaatgctgcgaagatcctagttgtcatcacagatggagaa
aaattcggtgatcccttggattataaggatgtcatccccgaggcagacagagcaggggtc
attcgctacgtaattggggtgggaaatgccttcaacaaaccacagtcccgcagagagctc
gacaccatcgcatctaagccagctggtgaacacgtgttccaagtggacaactttgaagcc
ctgaataccattcagaaccagcttcaggaaaagatctttgcaattgagggcacgcagaca
ggaagtaccagctcctttgagcatgagatgtctcaagaaggcttcagtgcttccattacc
tctaatggtcccttgctgggctctgtggggagctttgactgggcaggtggagccttcctg
tatacatcgaaggataaagtcaccttcatcaacacaaccagagtggattcagacatgaat
gatgcttacctgggttatgcttctgcagtcatcttgaggaaccgtgtccaaagcttggtt
ttaggagcacctcggtatcagcatattggcttggtggtgatgttcagggagaatttcggt
acctgggagccccacactagcatcaagggcagccagattggctcttattttggggcctcc
ctttgctctgtggacatggacgctgatggcaataccaacttgatcctcattggggcccct
cattactatgagaagacccgaggaggccaggtgtcagtgtgtcccttgcctcgagggcag
agggcacggtggcagtgtgaagctcttctccacggtgatcagggtcatccctggggtcgc
tttggggcagccctgacagtgctgggagacgtgaatggggacaaactgacagatgtggcc
attggggccccaggagagcaggagaatcagggcgctgtctacattttttatggagcatca
atagccagcctcagtgcctcccacagccagcggatcataggcgcccacttctcccctggg
ctccagtacttcgggcagtctctgagtgggggtaaggatctcacaatggatggcttgatg
gacctggctgttggggcgcaggggcatcttctgctgctcagagcccagccggtgctgaga
ctggaggcaaccatggaattcagccccaagaaagtagcaaggagtgtgtttgcatgtcaa
gaacaagtattaaaaaacaaggatgctggggaggtcagagtctgcctccgtgtccgcaag
aacaccaaggaccgtctgcgcgaaggagatatccagagcactgtcacttatgacctggct
ttagaccctggccgctcacgtatccgtgccttctttgatgagacaaagaacaacacacgc
aggcgcacccaggtctttggattgatgcagaaatgtgaaacactgaagctaattttaccg
gactgcgtggacgactcagtgagccccatcatcctgcgcctcaattatacactggttggg
gagcccttgaggtcctttgggaacctccgaccagttctggctatggatgctcagaggttc
ttcacagctatgtttccctttgagaaaaattgcggcaatgacagcatctgccaagacgat
ctcagcatcaccatgagtgccatgggcttggacactttggtggtgggaggcccccaggac
tttaacatgagtgtgactctgagaaatgacggtgaggattcctacgggacccaggttacc
gtctactacccatctggcttatcttaccggaaggattcagcaagccagaacccgctcacc
aagaagccttggtttgtaaagcctgctgagtccagctcttcttctgaagggcatggggct
ctgaagagtaccacctggaacataaaccatcccatctttcctgctaattctgaggtcaca
tttaatgtcacatttgatgtggactctcatgcctcctttgggaacaaactgctcctcaaa
gccattgtggccagtgagaacaacatgtccaggacccacaaaaccaagtttcagttggag
ctgcctgtgaagtacgccatctacatgattgtcaccagtgatgagagttctatcagatat
ctcaacttcacggcttcagagatgaccagtaaggtcatacagcatcagtaccagttcaac
aacctgggccagaggagcctccctgtcagtgtagtcttctggatccctgttcagatcaac
aatgtgaccgtatgggatcatccccaggtcatcttctcccagaacctctcaagtgcctgt
cacactgagcagaaatccccccctcactccaatttccgggatcagcttgaaaggacccca
gtgctgaactgctctgttgcagtctgtaagagaattcagtgtgaccttccatccttcaac
actcaggaaatattcaatgtcaccctcaagggcaacctatcatttgactggtacatcaag
acttctcatggtcacctcctgcttgtgagcagcactgagatcctgtttaatgactctgcg
tttgccctgcttccagggcaggagtcgtatgtgaggtctaagacagagaccaaagtggag
ccatatgaagttcacaatcctgtaccactcattgtgggcagctccattgggggcctggtg
ctcttggctctcatcactgctggcctatacaagcttggctttttcaagcggcagtacaag
gacatgatgaatgaagctgccccccaagacgccccacctcagtaa

  All links  
Ontology (6)   
   KEGG BRITE (6)   
Pathway (16)   
   KEGG PATHWAY (16)   
Genome (1)   
   KEGG GENOME (1)   
Gene (32)   
   KEGG ORTHOLOGY (1)   
   KEGG GENES (1)   
   RefGene (25)   
   NCBI-PROTEINID (1)   
   NCBI-Gene (1)   
   Ensembl (1)   
   OC (1)   
   VEGA (1)   
Protein sequence (3)   
   UniProt (1)   
   RefSeq(pep) (2)   
DNA sequence (32)   
   RefSeq(nuc) (2)   
   GenBank (15)   
   EMBL (15)   
Protein domain (8)   
   Pfam (8)   
All databases (98)   

Download RDF
KEGG   Mus musculus (mouse): 16414
Entry
16414             CDS       T01002                                 

Gene name
Itgb2, 2E6, AI528527, Cd18, LAD, LCAMB, Lfa1, MF17
Definition
(RefSeq) integrin beta 2
  KO
K06464  integrin beta 2
Organism
mmu  Mus musculus (mouse)
Pathway
mmu04015  Rap1 signaling pathway
mmu04145  Phagosome
mmu04390  Hippo signaling pathway
mmu04514  Cell adhesion molecules
mmu04610  Complement and coagulation cascades
mmu04613  Neutrophil extracellular trap formation
mmu04650  Natural killer cell mediated cytotoxicity
mmu04670  Leukocyte transendothelial migration
mmu04810  Regulation of actin cytoskeleton
mmu05133  Pertussis
mmu05134  Legionellosis
mmu05140  Leishmaniasis
mmu05144  Malaria
mmu05146  Amoebiasis
mmu05150  Staphylococcus aureus infection
mmu05152  Tuberculosis
mmu05166  Human T-cell leukemia virus 1 infection
mmu05323  Rheumatoid arthritis
mmu05416  Viral myocarditis
Brite
KEGG Orthology (KO) [BR:mmu00001]
 09130 Environmental Information Processing
  09132 Signal transduction
   04015 Rap1 signaling pathway
    16414 (Itgb2)
   04390 Hippo signaling pathway
    16414 (Itgb2)
  09133 Signaling molecules and interaction
   04514 Cell adhesion molecules
    16414 (Itgb2)
 09140 Cellular Processes
  09141 Transport and catabolism
   04145 Phagosome
    16414 (Itgb2)
  09142 Cell motility
   04810 Regulation of actin cytoskeleton
    16414 (Itgb2)
 09150 Organismal Systems
  09151 Immune system
   04610 Complement and coagulation cascades
    16414 (Itgb2)
   04613 Neutrophil extracellular trap formation
    16414 (Itgb2)
   04650 Natural killer cell mediated cytotoxicity
    16414 (Itgb2)
   04670 Leukocyte transendothelial migration
    16414 (Itgb2)
 09160 Human Diseases
  09172 Infectious disease: viral
   05166 Human T-cell leukemia virus 1 infection
    16414 (Itgb2)
  09171 Infectious disease: bacterial
   05133 Pertussis
    16414 (Itgb2)
   05134 Legionellosis
    16414 (Itgb2)
   05150 Staphylococcus aureus infection
    16414 (Itgb2)
   05152 Tuberculosis
    16414 (Itgb2)
  09174 Infectious disease: parasitic
   05146 Amoebiasis
    16414 (Itgb2)
   05144 Malaria
    16414 (Itgb2)
   05140 Leishmaniasis
    16414 (Itgb2)
  09163 Immune disease
   05323 Rheumatoid arthritis
    16414 (Itgb2)
  09166 Cardiovascular disease
   05416 Viral myocarditis
    16414 (Itgb2)
 09180 Brite Hierarchies
  09182 Protein families: genetic information processing
   04131 Membrane trafficking [BR:mmu04131]
    16414 (Itgb2)
  09183 Protein families: signaling and cellular processes
   04147 Exosome [BR:mmu04147]
    16414 (Itgb2)
   04515 Cell adhesion molecules [BR:mmu04515]
    16414 (Itgb2)
   04090 CD molecules [BR:mmu04090]
    16414 (Itgb2)
Membrane trafficking [BR:mmu04131]
 Endocytosis
  Phagocytosis
   Integrins (complement receptors)
    16414 (Itgb2)
Exosome [BR:mmu04147]
 Exosomal proteins
  Exosomal proteins of haemopoietic cells  (B-cell, T-cell, DC-cell, reticulocyte, and mast cell)
   16414 (Itgb2)
Cell adhesion molecules [BR:mmu04515]
 Integrins
  Integrin beta subunits
   16414 (Itgb2)
CD molecules [BR:mmu04090]
 Proteins
  16414 (Itgb2)
SSDB
Motif
Pfam: Integrin_beta Integrin_b_cyt Integrin_B_tail PSI_integrin EGF_2
Other DBs
NCBI-GeneID: 16414
NCBI-ProteinID: NP_032430
MGI: 96611
Ensembl: ENSMUSG00000000290
Vega: OTTMUSG00000019985
UniProt: P11835 Q542I8
Position
10 C1; 10 39.72 cM
AA seq 770 aa
MLGPHSLLLALAGLFFLGSAVSQECTKYKVSSCRDCIQSGPGCSWCQKLNFTGPGEPDSL
RCDTRAQLLLKGCPADDIMDPRSIANPEFDQRGQRKQLSPQKVTLYLRPGQAAAFNVTFR
RAKGYPIDLYYLMDLSYSMLDDLNNVKKLGGDLLQALNEITESGRIGFGSFVDKTVLPFV
NTHPEKLRNPCPNKEKACQPPFAFRHVLKLTDNSNQFQTEVGKQLISGNLDAPEGGLDAI
MQVAACPEEIGWRNVTRLLVFATDDGFHFAGDGKLGAILTPNDGRCHLEDNMYKRSNEFD
YPSVGQLAHKLSESNIQPIFAVTKKMVKTYEKLTEIIPKSAVGELSDDSSNVVQLIKNAY
YKLSSRVFLDHSTLPDTLKVTYDSFCSNGASSIGKSRGDCDGVQINNPVTFQVKVMASEC
IQEQSFVIRALGFTDTVTVQVRPQCECQCRDQSREQSLCGGKGVMECGICRCESGYIGKN
CECQTQGRSSQELERNCRKDNSSIVCSGLGDCICGQCVCHTSDVPNKEIFGQYCECDNVN
CERYNSQVCGGSDRGSCNCGKCSCKPGYEGSACQCQRSTTGCLNARLVECSGRGHCQCNR
CICDEGYQPPMCEDCPSCGSHCRDNHTSCAECLKFDKGPFEKNCSVQCAGMTLQTIPLKK
KPCKERDSEGCWITYTLQQKDGRNIYNIHVEDSLECVKGPNVAAIVGGTVVGVVLIGVLL
LVIWKALTHLTDLREYRRFEKEKLKSQWNNDNPLFKSATTTVMNPKFAES
NT seq 2313 nt   +upstreamnt  +downstreamnt
atgctgggcccacactcactgctgcttgccctagctggactgttcttcctgggatctgct
gtgtcccaggaatgcaccaagtacaaagtcagcagttgccgggactgtatccagtcgggg
cctggctgttcctggtgccagaagctgaacttcactggaccaggagaacctgactccttg
cgctgtgacacacgggcacagctgctgctgaagggttgtccagccgatgatatcatggac
cccaggagcatcgctaatcctgagttcgaccaacgggggcaacggaaacagctatctcca
caaaaagtgacactttacttgcgaccaggacaggctgccgcattcaatgtgactttccgg
cgggccaagggataccccattgatctgtactacctcatggatctctcctactccatgctt
gatgacctcaacaacgtcaagaagctgggcggggacttgctgcaggccctcaacgagatc
accgagtctggccgcatcggctttgggtcgtttgtggacaagacggtgctgccttttgtt
aacacccatcctgagaagctgaggaacccatgtcccaacaaggagaaggcctgccagccc
ccatttgcctttcggcacgtgctcaagttaaccgacaactccaaccagtttcagacagag
gtcggcaagcaactgatttccggaaacctggacgcccctgagggtgggctggatgccata
atgcaagttgctgcatgtccggaggaaattggctggcgcaatgtcacgaggctgctggtg
tttgccacagacgatggcttccactttgctggtgatggcaaactgggtgccatcctgacc
cccaatgatggccgctgccacctggaggataacatgtacaagaggagcaatgagttcgac
tacccatccgtgggtcagctggcacacaaactttccgagagcaacatccagcccatcttt
gcggtgacaaagaagatggtgaaaacgtatgagaaactcacggagatcatccccaagtca
gcagtgggggaactgtctgacgactccagcaacgtggtgcagctcatcaagaatgcctac
tataaactctcctctagagtcttcctggaccacagcaccctcccggacaccctgaaagtc
acctatgactccttctgcagtaatggagcatcgagtataggcaaatcccgtggggactgt
gatggcgtacagatcaacaacccggtcaccttccaggtaaaggtcatggcttccgagtgt
atccaggagcagtcctttgtcatccgggcactgggtttcacggatacagtgaccgtgcag
gtccgtccccagtgtgagtgtcagtgccgggaccagagtcgggagcagagtctctgtgga
ggcaagggagtcatggagtgtggtatctgcaggtgtgagtctggctacattgggaaaaac
tgtgagtgccagactcagggtcggagcagccaggagctggagagaaactgtcggaaggac
aatagttccatcgtgtgctcagggcttggggactgcatctgtgggcagtgtgtatgccat
accagtgacgtccccaacaaagagatctttgggcaatactgcgagtgtgacaatgtcaac
tgtgagagatataacagccaagtctgcggtggctcagatcggggttcctgcaactgtggc
aaatgtagttgcaagcccggttacgagggctcggcctgccagtgtcagaggtccaccacg
ggctgtctgaatgcacggctggtagagtgcagtggccgtggccactgccaatgcaacagg
tgcatatgtgacgaaggctaccagccaccgatgtgtgaggattgtcccagctgtggctcg
cactgcagggacaaccacacctcttgtgccgagtgcctgaagtttgataagggccctttt
gagaagaactgtagtgttcagtgtgctggtatgacgctgcagactatccctttgaagaaa
aagccctgcaaggagagggactcggaaggctgttggataacttacactttgcagcagaag
gacggaaggaacatttacaacatccatgtggaggacagtctagagtgtgtgaagggcccc
aatgtggctgccatcgtagggggcaccgtggtaggtgtcgtactgattggtgtcctcctc
ctggtcatctggaaggccctgacccacctgactgacctcagggagtacaggcgctttgag
aaggagaaactcaagtcccaatggaacaatgacaaccccctcttcaagagtgctacgaca
acggtcatgaaccccaagtttgctgaaagctag

  All links  
Ontology (5)   
   KEGG BRITE (5)   
Pathway (19)   
   KEGG PATHWAY (19)   
Genome (1)   
   KEGG GENOME (1)   
Gene (41)   
   KEGG ORTHOLOGY (1)   
   KEGG GENES (1)   
   RefGene (34)   
   NCBI-PROTEINID (1)   
   NCBI-Gene (1)   
   Ensembl (1)   
   OC (1)   
   VEGA (1)   
Protein sequence (7)   
   UniProt (2)   
   SWISS-PROT (1)   
   RefSeq(pep) (4)   
DNA sequence (22)   
   RefSeq(nuc) (6)   
   GenBank (8)   
   EMBL (8)   
Protein domain (5)   
   Pfam (5)   
All databases (100)   

Download RDF
KEGG   Mus musculus (mouse): 16415
Entry
16415             CDS       T01002                                 

Gene name
Itgb2l, 5033406G21Rik, pac, pactolus
Definition
(RefSeq) integrin beta 2-like
  KO
K06464  integrin beta 2
Organism
mmu  Mus musculus (mouse)
Pathway
mmu04015  Rap1 signaling pathway
mmu04145  Phagosome
mmu04390  Hippo signaling pathway
mmu04514  Cell adhesion molecules
mmu04610  Complement and coagulation cascades
mmu04613  Neutrophil extracellular trap formation
mmu04650  Natural killer cell mediated cytotoxicity
mmu04670  Leukocyte transendothelial migration
mmu04810  Regulation of actin cytoskeleton
mmu05133  Pertussis
mmu05134  Legionellosis
mmu05140  Leishmaniasis
mmu05144  Malaria
mmu05146  Amoebiasis
mmu05150  Staphylococcus aureus infection
mmu05152  Tuberculosis
mmu05166  Human T-cell leukemia virus 1 infection
mmu05323  Rheumatoid arthritis
mmu05416  Viral myocarditis
Brite
KEGG Orthology (KO) [BR:mmu00001]
 09130 Environmental Information Processing
  09132 Signal transduction
   04015 Rap1 signaling pathway
    16415 (Itgb2l)
   04390 Hippo signaling pathway
    16415 (Itgb2l)
  09133 Signaling molecules and interaction
   04514 Cell adhesion molecules
    16415 (Itgb2l)
 09140 Cellular Processes
  09141 Transport and catabolism
   04145 Phagosome
    16415 (Itgb2l)
  09142 Cell motility
   04810 Regulation of actin cytoskeleton
    16415 (Itgb2l)
 09150 Organismal Systems
  09151 Immune system
   04610 Complement and coagulation cascades
    16415 (Itgb2l)
   04613 Neutrophil extracellular trap formation
    16415 (Itgb2l)
   04650 Natural killer cell mediated cytotoxicity
    16415 (Itgb2l)
   04670 Leukocyte transendothelial migration
    16415 (Itgb2l)
 09160 Human Diseases
  09172 Infectious disease: viral
   05166 Human T-cell leukemia virus 1 infection
    16415 (Itgb2l)
  09171 Infectious disease: bacterial
   05133 Pertussis
    16415 (Itgb2l)
   05134 Legionellosis
    16415 (Itgb2l)
   05150 Staphylococcus aureus infection
    16415 (Itgb2l)
   05152 Tuberculosis
    16415 (Itgb2l)
  09174 Infectious disease: parasitic
   05146 Amoebiasis
    16415 (Itgb2l)
   05144 Malaria
    16415 (Itgb2l)
   05140 Leishmaniasis
    16415 (Itgb2l)
  09163 Immune disease
   05323 Rheumatoid arthritis
    16415 (Itgb2l)
  09166 Cardiovascular disease
   05416 Viral myocarditis
    16415 (Itgb2l)
 09180 Brite Hierarchies
  09182 Protein families: genetic information processing
   04131 Membrane trafficking [BR:mmu04131]
    16415 (Itgb2l)
  09183 Protein families: signaling and cellular processes
   04147 Exosome [BR:mmu04147]
    16415 (Itgb2l)
   04515 Cell adhesion molecules [BR:mmu04515]
    16415 (Itgb2l)
   04090 CD molecules [BR:mmu04090]
    16415 (Itgb2l)
Membrane trafficking [BR:mmu04131]
 Endocytosis
  Phagocytosis
   Integrins (complement receptors)
    16415 (Itgb2l)
Exosome [BR:mmu04147]
 Exosomal proteins
  Exosomal proteins of haemopoietic cells  (B-cell, T-cell, DC-cell, reticulocyte, and mast cell)
   16415 (Itgb2l)
Cell adhesion molecules [BR:mmu04515]
 Integrins
  Integrin beta subunits
   16415 (Itgb2l)
CD molecules [BR:mmu04090]
 Proteins
  16415 (Itgb2l)
SSDB
Motif
Pfam: Integrin_beta PSI_integrin EGF_2 I-EGF_1 Tmemb_9
Other DBs
NCBI-GeneID: 16415
NCBI-ProteinID: NP_032431
MGI: 1277979
Ensembl: ENSMUSG00000000157
Vega: OTTMUSG00000020391
UniProt: Q3UV74
Structure
PDB: 
2IUE

Position
16; 16 C4
AA seq 738 aa
MLGQCTLLPVLAGLLSLESALSQLCTKDNVSTCQDCIRSGPSCAWCQKLNFTGRGEPDSV
RCDTPEQLLLKGCTSEYLVDPKSLAESQEDKERDQRQLSPRNVTVFLRPGQAATFKVDFQ
RTQDNSVDLYFLMGLSGSAQGHLSNVQTLGSDLLKALNEISRSGRIGFGSIVNMTFQHIL
KLTADSSQFQRELRKQLVSGKLATPKGQLDAVVQVAICLGEIGWRNGTRFLVLVTDNDFH
LAKDKTLGTRQNTSDGRCHLDDGMYRSRGEPDYQSVVQLASKLAENNIQPIFVVPSRMVK
TYEKLTTFIPKLTIGELSDDSSNVAQLIRNAYSKLSSIVVLNHSTIPSILKVTYDSYCSN
GTSNPGKPSGDCSGVQINDQVTFQVNITASECFREQFFFIQALGFMDSVTVRVLPLCECQ
CQEQSQHHSLCGGKGAMECGICRCNSGYAGKNCECQTQGPSSQDLEGSCRKDNSSIMCSG
LGDCICGQCECHTSDIPNKEIYGQYCECNNVNCERYDGQVCGGPERGHCSCGRCFCRYGF
VGSACQCRMSTSGCLNNRMVECSGHGRCYCNRCLCDPGYQPPLCEKRPGYFHRCSEYYSC
ARCLKDNSAIKCRECWNLLFSNTPFSNKTCMTERDSEGCWTTYTLYQPDQSDINSIYIKE
SLVCAEISNTTILLGVIVGVLLAVIFLLVYCMVYLKGTQKAAKLPRKGGAQSTLAQQPHF
QEPHHVEPVWNQERQGTQ
NT seq 2217 nt   +upstreamnt  +downstreamnt
atgctgggccagtgcactctgctacctgtcctagctgggctgctgtctctggaatctgca
ctgtctcagttgtgtaccaaggacaatgtgagcacctgtcaggactgtatccggtcaggg
cccagctgtgcctggtgccagaagctgaacttcacagggcgaggggagcccgactcagtt
cgctgtgatacaccagagcaactgttgctaaaaggctgcacatctgagtacctcgtggac
cccaagagtcttgctgaatcccaggaagacaaggagagggaccagaggcagctgtctcca
cgaaatgtgacagttttcttaagaccgggtcaagcggcaacattcaaagtggacttccag
cggacccaggacaactctgttgacctgtacttcctgatgggcctctctggctctgcgcaa
ggccacctctccaatgtccagacactgggcagtgacctgctcaaagccctcaatgagatc
tccaggtcaggccgaatcggctttggatccattgtgaacatgaccttccagcacatcctg
aagctgactgcggactccagccaatttcagagggagctgaggaagcaactggtttctgga
aagctggctacccccaagggacagctggatgctgtggttcaagttgccatatgcctggga
gaaatcggctggcgcaatgggacccgatttctggtgcttgttactgacaacgatttccac
ttggctaaagacaagactctgggtaccagacagaacaccagcgatggtcgctgtcacctg
gacgacggcatgtacaggagcaggggagaacctgactaccagtcagtggtccagctggca
agcaaactggctgaaaacaacatccagcccatcttcgtggtgccctcaaggatggtgaaa
acctatgagaaacttaccacattcatccccaagctgaccattggggagctgtcagatgac
tccagcaacgtggcacagctcatcaggaacgcctacagtaaactctcctccattgttgtg
ctgaaccacagcaccatccccagcatcctgaaagttacctacgactcctactgcagcaat
ggaacatcaaatccaggcaaacccagcggggactgcagtggtgtacagatcaatgaccag
gtcaccttccaggttaacatcacagcttcagagtgcttccgggagcagttctttttcatc
caggcactgggcttcatggattcagtgaccgtgcgggtccttcccctgtgtgagtgccag
tgccaggagcagagtcaacaccacagcctctgtggaggcaagggagccatggagtgtggc
atctgcaggtgcaactctggctacgctgggaaaaactgtgagtgccagacacagggcccg
agcagccaggatctggagggaagctgccggaaggacaatagttccatcatgtgctcgggg
ctgggagactgtatctgtgggcagtgtgagtgccacaccagtgacatccccaacaaagag
atctatgggcaatactgcgagtgcaacaatgtcaactgtgagagatatgatggccaagtc
tgcggtggcccagaaagaggccactgctcctgtggccgatgcttttgtcgttacggcttc
gtgggctcagcctgccagtgccggatgtccacttcaggctgtctgaacaacaggatggtg
gagtgcagtggccatggtcgatgctactgtaacagatgcctctgtgacccgggctaccag
ccaccactgtgtgagaagcgtcctggctatttccatcgctgctccgagtactactcctgt
gccaggtgcttgaaagacaacagtgcaataaaatgcagagagtgttggaatctgctgttt
tccaacacccccttcagtaacaagacctgcatgactgaacgggactcagagggctgttgg
acaacctacactctatatcagccagaccagagtgacatcaattccatctacataaaggag
agcctagtgtgtgcagaaatctccaataccaccatcctactgggcgttatagtgggcgtc
ttgctggctgttatcttcctgctggtttactgtatggtttacctgaagggaacccagaag
gctgccaagctccccagaaagggtggggctcaaagcacactggcacagcagcctcatttc
caagaaccccaccatgtggagccagtgtggaatcaagagagacagggtacccaatga

  All links  
Ontology (5)   
   KEGG BRITE (5)   
Pathway (19)   
   KEGG PATHWAY (19)   
Genome (1)   
   KEGG GENOME (1)   
Gene (66)   
   KEGG ORTHOLOGY (1)   
   KEGG GENES (1)   
   RefGene (59)   
   NCBI-PROTEINID (1)   
   NCBI-Gene (1)   
   Ensembl (1)   
   OC (1)   
   VEGA (1)   
Protein sequence (5)   
   UniProt (1)   
   SWISS-PROT (1)   
   RefSeq(pep) (3)   
DNA sequence (15)   
   RefSeq(nuc) (3)   
   GenBank (6)   
   EMBL (6)   
Protein domain (5)   
   Pfam (5)   
All databases (116)   

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