KEGG   Mus musculus (mouse): 16410
Entry
16410             CDS       T01002                                 

Gene name
Itgav, 1110004F14Rik, 2610028E01Rik, CD51, D430040G12Rik
Definition
(RefSeq) integrin alpha V
  KO
K06487  integrin alpha V
Organism
mmu  Mus musculus (mouse)
Pathway
mmu04145  Phagosome
mmu04151  PI3K-Akt signaling pathway
mmu04510  Focal adhesion
mmu04512  ECM-receptor interaction
mmu04514  Cell adhesion molecules
mmu04810  Regulation of actin cytoskeleton
mmu04919  Thyroid hormone signaling pathway
mmu05163  Human cytomegalovirus infection
mmu05165  Human papillomavirus infection
mmu05200  Pathways in cancer
mmu05205  Proteoglycans in cancer
mmu05222  Small cell lung cancer
mmu05410  Hypertrophic cardiomyopathy
mmu05412  Arrhythmogenic right ventricular cardiomyopathy
mmu05414  Dilated cardiomyopathy
mmu05418  Fluid shear stress and atherosclerosis
Brite
KEGG Orthology (KO) [BR:mmu00001]
 09130 Environmental Information Processing
  09132 Signal transduction
   04151 PI3K-Akt signaling pathway
    16410 (Itgav)
  09133 Signaling molecules and interaction
   04512 ECM-receptor interaction
    16410 (Itgav)
   04514 Cell adhesion molecules
    16410 (Itgav)
 09140 Cellular Processes
  09141 Transport and catabolism
   04145 Phagosome
    16410 (Itgav)
  09144 Cellular community - eukaryotes
   04510 Focal adhesion
    16410 (Itgav)
  09142 Cell motility
   04810 Regulation of actin cytoskeleton
    16410 (Itgav)
 09150 Organismal Systems
  09152 Endocrine system
   04919 Thyroid hormone signaling pathway
    16410 (Itgav)
 09160 Human Diseases
  09161 Cancer: overview
   05200 Pathways in cancer
    16410 (Itgav)
   05205 Proteoglycans in cancer
    16410 (Itgav)
  09162 Cancer: specific types
   05222 Small cell lung cancer
    16410 (Itgav)
  09172 Infectious disease: viral
   05163 Human cytomegalovirus infection
    16410 (Itgav)
   05165 Human papillomavirus infection
    16410 (Itgav)
  09166 Cardiovascular disease
   05418 Fluid shear stress and atherosclerosis
    16410 (Itgav)
   05410 Hypertrophic cardiomyopathy
    16410 (Itgav)
   05412 Arrhythmogenic right ventricular cardiomyopathy
    16410 (Itgav)
   05414 Dilated cardiomyopathy
    16410 (Itgav)
 09180 Brite Hierarchies
  09182 Protein families: genetic information processing
   04131 Membrane trafficking [BR:mmu04131]
    16410 (Itgav)
  09183 Protein families: signaling and cellular processes
   04147 Exosome [BR:mmu04147]
    16410 (Itgav)
   04515 Cell adhesion molecules [BR:mmu04515]
    16410 (Itgav)
   04090 CD molecules [BR:mmu04090]
    16410 (Itgav)
Membrane trafficking [BR:mmu04131]
 Endocytosis
  Phagocytosis
   Integrins (complement receptors)
    16410 (Itgav)
Exosome [BR:mmu04147]
 Exosomal proteins
  Exosomal proteins of haemopoietic cells  (B-cell, T-cell, DC-cell, reticulocyte, and mast cell)
   16410 (Itgav)
  Exosomal proteins of epithelial cells
   16410 (Itgav)
Cell adhesion molecules [BR:mmu04515]
 Integrins
  Integrin alpha subunits
   16410 (Itgav)
CD molecules [BR:mmu04090]
 Proteins
  16410 (Itgav)
SSDB
Motif
Pfam: Integrin_alpha2 FG-GAP FG-GAP_3 Integrin_alpha LYRIC DctQ Collectrin
Other DBs
NCBI-GeneID: 16410
NCBI-ProteinID: NP_032428
MGI: 96608
Ensembl: ENSMUSG00000027087
Vega: OTTMUSG00000013360
UniProt: P43406
Position
2 D; 2 49.33 cM
AA seq 1044 aa
MAAPGRLLLRPRPGGLLLLLPGLLLPLADAFNLDVESPAEYAGPEGSYFGFAVDFFEPST
SSRMFLLVGAPKANTTQPGIVEGGQVLKCECSSSRRCQPIEFDSTGNRDYAKDDPLEFKS
HQWFGASVRSKQDKILACAPLYHWRTEMKQEREPVGTCFLQDGTKTVEYAPCRSKNIDAD
GQGFCQGGFSIDFTKADRVLLGGPGSFYWQGQLISDQVAEIISKYDPNVYSIKYNNQLAT
RTAQAIFDDSYLGYSVAVGDFNGDGIEDFVSGVPRAARTLGMVYIYDGKNMSSLHNFTGE
QMAAYFGFSVAATDINGDDYADVFIGAPLFMDRGSDGKLQEVGQVSVSLQRAVGDFQTTK
LNGFEVFARFGSAIAPLGDLDQDGFNDIAIAAPYGGEDKKGLVYIFNGRSTGLNSVPSQI
LEGQWAAQSMPPSFGYSMKGATDVDRNGYPDLVVGAFGVDRAVLYRARPVVTVNAGLEVY
PSILNQDNKICPLPGTALKVSCFNVRFCLKADGKGTLPRKLHFQVELLLDKLKQKGAIRR
ALFLHNRSPVHSKTMTVFRGGQMQCEELVAYLRDESEFRDKLTPITIFMEYRLDQRTAAD
ATGLQPILNQFTPANVSRQAHILLDCGEDNVCKPKLEVSVNSDQKKIYIGDDNPLTLTVK
AQNQGEGAYEAELIVSIPPQADFIGVVRNNEALARLSCAFKTENQTRQVVCDLGNPMKAG
TQLLAGLRFSVHQQSEMDTSVKFDLKIQSSNSFDNVSPVVSYKVDLAVLAAVEIRGVSSP
DHIFLPIPNWEYKENPETEEDVGPIVQHIYELRNNGPSSFSKAILNLQWPYKYNNNTLLY
ILHYDIDGPMNCTADTEINPLRIKTPEKNDTAAAGQGERNHLITKRDLTLREGDVHTLGC
GIAKCLQITCQVGRLDRGKSAILYVKSLLWTETFMNKENQNHSYSLKSSASFNIIEFPYK
NLPIEDLFNSTLVTTNITWGIQPAPMPVPVWVIILAVLAGLLLLAVLVFVMYRMGFFKRV
RPPQEEQEREQLQPHENGEGNSET
NT seq 3135 nt   +upstreamnt  +downstreamnt
atggctgctcccgggcgcctgctgctacgccctcgccccggcggcctcctgctgctgctg
ccgggtctcctgctgcccctcgccgacgccttcaacctggacgtcgaaagtcccgccgag
tatgcgggtcccgagggaagttacttcggattcgccgtggacttcttcgagcccagcacg
tcctccaggatgtttctcctggtgggagcccccaaagcgaacacgacccagcctgggatt
gtagaaggagggcaagttctcaaatgtgaatgctcatccagccgccggtgccagcccatt
gagtttgattcaacaggcaatcgagattatgccaaagatgacccactggagtttaagtcc
caccagtggtttggagcctctgtgaggtcaaagcaggataaaatcttggcctgtgctcca
ttgtaccactggaggactgagatgaagcaggagagagagccagttggaacctgctttctt
caggacggcacaaagaccgttgagtatgctccatgcaggtcaaaaaatattgatgctgat
ggccagggattttgtcaaggaggattcagcattgattttactaaagctgacagagtactt
ctcggtggtcctggtagcttttattggcaaggtcagctcatttcggaccaagtggcagaa
atcatatctaaatatgacccaaatgtctacagcatcaaatataataaccaattagcaaca
cggactgcacaagcaatttttgatgacagttatttgggttactctgtggccgtgggagac
ttcaatggtgacggcattgaagattttgtctcaggagttccaagagcagcaaggactttg
ggaatggtttatatttatgatgggaaaaatatgtcctctttacacaattttactggtgaa
cagatggctgcgtattttggattttctgtagctgctactgacattaatggggatgattac
gcagatgtgtttattggagcccccctgttcatggaccgaggttccgatgggaaactccag
gaggttggccaggtctcagtgtctctgcagagagcagtgggagacttccagactacaaag
ctgaacggctttgaggtttttgccaggtttggaagtgccatagctccattgggagacctg
gaccaggatggcttcaatgatattgcaattgctgctccctatggtggtgaagataagaag
ggacttgtttatatcttcaatggaaggtccacaggcttgaattcggtgccatctcaaatc
ctcgaggggcagtgggctgctcagagcatgcccccaagctttggctattcaatgaaggga
gctacagatgtagacaggaatggatatccagacttagttgtaggagcttttggtgtggat
cgagctgtcttatacagagccagacccgttgtcactgtaaatgctggccttgaagtgtac
cctagcattttaaatcaagacaataagatctgcccgttgcctgggacagctctcaaggtt
tcctgttttaatgtcagattctgcttaaaggcagatggcaagggaacccttcctcggaag
ctccacttccaggtggagcttctactggataaactcaagcagaagggagccatccgacga
gcactgtttctccataacaggtccccggtccactccaagaccatgactgttttcaggggg
ggacagatgcagtgtgaggaactggtcgcctatcttcgggatgaatctgaatttagagac
aagctcactcccatcaccattttcatggagtatcggttggaccagagaacggctgctgat
gccacaggcttgcagcccatcctgaaccagttcactccggccaacgtcagtcggcaggct
catattctacttgactgtggtgaagacaatgtctgtaaacctaaattggaagtttctgta
aatagtgatcaaaagaagatctatattggggacgacaaccctctgacactgactgtgaag
gcgcagaatcaaggggaaggcgcctatgaagctgagctcatcgtttctatcccaccgcag
gctgacttcatcggggttgtccggaacaacgaagccttagcaagactgtcctgtgcattt
aagacagaaaaccaaactcggcaggtggtgtgcgaccttggaaacccgatgaaggctgga
actcaactgctcgctggtcttcgtttcagcgtgcaccagcagtcagagatggatacttct
gtgaagtttgacttgaaaatccagagctctaattcttttgacaatgtaagtccagttgtg
tcttacaaggttgacctcgccgttttggctgctgtggagataagaggagtttcaagtcca
gatcatatctttcttccaattccaaattgggagtacaaggaaaaccctgagactgaagaa
gacgttgggcctattgttcagcacatatatgagctgagaaacaatggtccaagttcattc
agcaaggcaattctaaatctccagtggccttacaaatacaacaacaacactctgttgtac
attcttcattacgacattgacgggccaatgaactgcacggcagatacagagatcaaccct
ttgagaatcaagacacccgaaaagaatgacacagcggcggcgggacagggagaaaggaat
catctcatcaccaagcgggatctcaccctcagagagggagatgttcacactttgggctgt
ggaatcgccaagtgcttgcagatcacctgccaggttggtcgactggatagaggcaagagc
gcaatcctgtacgtgaaatccctgctgtggaccgagacgttcatgaacaaggagaaccag
aaccattcctattcgctgaagtcatctgcttcctttaatatcatagaattcccttacaag
aacctgccgatcgaggatctcttcaactctacactagtcaccactaacatcacctggggc
attcagccggcgcccatgcctgtgcctgtgtgggtgatcatcttggcagttctcgcaggg
ctgctgctactggctgtgttggtatttgtaatgtacaggatgggctttttcaaacgtgtc
cgaccacctcaagaagagcaagaaagagaacagcttcagcctcatgagaatggcgaagga
aactctgaaacctaa

KEGG   Mus musculus (mouse): 16416
Entry
16416             CDS       T01002                                 

Gene name
Itgb3, CD61, GP3A, INGRB3
Definition
(RefSeq) integrin beta 3
  KO
K06493  integrin beta 3
Organism
mmu  Mus musculus (mouse)
Pathway
mmu04015  Rap1 signaling pathway
mmu04145  Phagosome
mmu04151  PI3K-Akt signaling pathway
mmu04380  Osteoclast differentiation
mmu04510  Focal adhesion
mmu04512  ECM-receptor interaction
mmu04611  Platelet activation
mmu04613  Neutrophil extracellular trap formation
mmu04640  Hematopoietic cell lineage
mmu04810  Regulation of actin cytoskeleton
mmu04919  Thyroid hormone signaling pathway
mmu05163  Human cytomegalovirus infection
mmu05165  Human papillomavirus infection
mmu05168  Herpes simplex virus 1 infection
mmu05205  Proteoglycans in cancer
mmu05206  MicroRNAs in cancer
mmu05410  Hypertrophic cardiomyopathy
mmu05412  Arrhythmogenic right ventricular cardiomyopathy
mmu05414  Dilated cardiomyopathy
mmu05418  Fluid shear stress and atherosclerosis
Brite
KEGG Orthology (KO) [BR:mmu00001]
 09130 Environmental Information Processing
  09132 Signal transduction
   04015 Rap1 signaling pathway
    16416 (Itgb3)
   04151 PI3K-Akt signaling pathway
    16416 (Itgb3)
  09133 Signaling molecules and interaction
   04512 ECM-receptor interaction
    16416 (Itgb3)
 09140 Cellular Processes
  09141 Transport and catabolism
   04145 Phagosome
    16416 (Itgb3)
  09144 Cellular community - eukaryotes
   04510 Focal adhesion
    16416 (Itgb3)
  09142 Cell motility
   04810 Regulation of actin cytoskeleton
    16416 (Itgb3)
 09150 Organismal Systems
  09151 Immune system
   04640 Hematopoietic cell lineage
    16416 (Itgb3)
   04611 Platelet activation
    16416 (Itgb3)
   04613 Neutrophil extracellular trap formation
    16416 (Itgb3)
  09152 Endocrine system
   04919 Thyroid hormone signaling pathway
    16416 (Itgb3)
  09158 Development and regeneration
   04380 Osteoclast differentiation
    16416 (Itgb3)
 09160 Human Diseases
  09161 Cancer: overview
   05206 MicroRNAs in cancer
    16416 (Itgb3)
   05205 Proteoglycans in cancer
    16416 (Itgb3)
  09172 Infectious disease: viral
   05168 Herpes simplex virus 1 infection
    16416 (Itgb3)
   05163 Human cytomegalovirus infection
    16416 (Itgb3)
   05165 Human papillomavirus infection
    16416 (Itgb3)
  09166 Cardiovascular disease
   05418 Fluid shear stress and atherosclerosis
    16416 (Itgb3)
   05410 Hypertrophic cardiomyopathy
    16416 (Itgb3)
   05412 Arrhythmogenic right ventricular cardiomyopathy
    16416 (Itgb3)
   05414 Dilated cardiomyopathy
    16416 (Itgb3)
 09180 Brite Hierarchies
  09182 Protein families: genetic information processing
   04131 Membrane trafficking [BR:mmu04131]
    16416 (Itgb3)
  09183 Protein families: signaling and cellular processes
   04147 Exosome [BR:mmu04147]
    16416 (Itgb3)
   04515 Cell adhesion molecules [BR:mmu04515]
    16416 (Itgb3)
   04090 CD molecules [BR:mmu04090]
    16416 (Itgb3)
Membrane trafficking [BR:mmu04131]
 Endocytosis
  Phagocytosis
   Integrins (complement receptors)
    16416 (Itgb3)
Exosome [BR:mmu04147]
 Exosomal proteins
  Exosomal proteins of haemopoietic cells  (B-cell, T-cell, DC-cell, reticulocyte, and mast cell)
   16416 (Itgb3)
Cell adhesion molecules [BR:mmu04515]
 Integrins
  Integrin beta subunits
   16416 (Itgb3)
CD molecules [BR:mmu04090]
 Proteins
  16416 (Itgb3)
SSDB
Motif
Pfam: Integrin_beta Integrin_b_cyt Integrin_B_tail I-EGF_1 PSI_integrin EGF_2
Other DBs
NCBI-GeneID: 16416
NCBI-ProteinID: NP_058060
MGI: 96612
Ensembl: ENSMUSG00000020689
Vega: OTTMUSG00000003177
UniProt: O54890
Position
11 E1; 11 67.84 cM
AA seq 787 aa
MRAQWPGQLWAALLALGALAGVVVGESNICTTRGVNSCQQCLAVSPVCAWCSDETLSQGS
PRCNLKENLLKDNCAPESIEFPVSEAQILEARPLSSKGSGSSAQITQVSPQRIALRLRPD
DSKIFSLQVRQVEDYPVDIYYLMDLSFSMKDDLSSIQTLGTKLASQMRKLTSNLRIGFGA
FVDKPVSPYMYISPPQAIKNPCYNMKNACLPMFGYKHVLTLTDQVSRFNEEVKKQSVSRN
RDAPEGGFDAIMQATVCDEKIGWRNDASHLLVFTTDAKTHIALDGRLAGIVLPNDGHCHI
GTDNHYSASTTMDYPSLGLMTEKLSQKNINLIFAVTENVVSLYQNYSELIPGTTVGVLSD
DSSNVLQLIVDAYGKIRSKVELEVRDLPEELSLSFNATCLNNEVIPGLKSCVGLKIGDTV
SFSIEAKVRGCPQEKEQSFTIKPVGFKDSLTVQVTFDCDCACQAFAQPSSPRCNNGNGTF
ECGVCRCDQGWLGSMCECSEEDYRPSQQEECSPKEGQPICSQRGECLCGQCVCHSSDFGK
ITGKYCECDDFSCVRYKGEMCSGHGQCNCGDCVCDSDWTGYYCNCTTRTDTCMSTNGLLC
SGRGNCECGSCVCVQPGSYGDTCEKCPTCPDACSFKKECVECKKFNRGTLHEENTCSRYC
RDDIEQVKELTDTGKNAVNCTYKNEDDCVVRFQYYEDTSGRAVLYVVEEPECPKGPDILV
VLLSVMGAILLIGLATLLIWKLLITIHDRKEFAKFEEERARAKWDTANNPLYKEATSTFT
NITYRGT
NT seq 2364 nt   +upstreamnt  +downstreamnt
atgcgagcgcagtggccgggacaactctgggccgctctgctggcgctgggggcgctggcg
ggcgttgttgttggagagtccaacatctgtaccacacgaggcgtgaactcctgccagcag
tgtctggctgtgagtcctgtgtgtgcctggtgctcagatgagactttgtctcagggctca
ccccgatgtaacctgaaggagaacctgctgaaggacaattgtgctccagagtctattgag
ttcccagtcagtgaggcccagatcctggaggctaggccactcagcagcaagggctctgga
agcagcgcccagatcactcaagtcagccctcagaggattgcccttcgactacggccagat
gattcgaagatcttctcacttcaagtgcggcaggtggaggattaccccgtggacatctac
tacttgatggacctgtctttctccatgaaggatgatctgtccagcatccagaccctgggt
accaagttggcctctcagatgcgcaagcttactagcaaccttcggattggctttggggcc
ttcgtggacaagcctgtatcgccgtacatgtacatctccccaccacaggcaatcaaaaac
ccctgttacaatatgaagaatgcctgcttgcccatgtttggctacaaacacgtgctgacg
ctaaccgaccaggtgtcccgcttcaatgaagaagtgaagaaacagagcgtgtcccgtaat
cgagatgccccagagggcggctttgacgccatcatgcaggctacagtatgtgatgaaaaa
attggctggaggaatgacgcatcccatttgctagtgtttaccacggatgccaagacccat
attgccctggatggaaggctggcaggcattgtcctgcccaatgatgggcactgtcacatt
ggcaccgacaaccactactctgcctccactaccatggactacccatctctggggctgatg
actgagaaactatcccagaaaaacattaacttgatctttgcagtgactgaaaatgtcgtc
agcctttaccagaattatagtgagctcattcctgggaccacagtgggagtcctgtctgat
gactcaagcaacgtcctccagctcattgttgatgcttacgggaaaatccgctctaaagtg
gagctggaagtacgtgacctgccggaagaactgtcactgtccttcaatgccacctgcctc
aacaacgaggttatcccgggcctcaagtcttgtgtgggcctcaagattggagacacggtg
agctttagtatcgaggccaaggtgcgtggctgcccccaggagaaggagcagtctttcact
atcaagcctgtgggctttaaggacagcctcaccgtccaggtgaccttcgactgtgactgt
gcctgccaggcctttgcccagccttccagcccacgctgcaacaatgggaacgggactttt
gagtgtggggtgtgccgctgtgaccagggctggctggggtccatgtgtgagtgctctgag
gaggattaccgaccctctcagcaggaagagtgcagccccaaggagggccagcccatctgc
agccagcggggagagtgcctctgtggccagtgtgtctgccatagcagcgacttcggcaag
atcactggcaagtactgtgagtgcgatgacttctcctgcgtccgctacaaaggggagatg
tgttccggccatgggcaatgtaactgtggggactgcgtgtgtgactcggactggactggc
tactactgcaactgtactacacgcactgacacctgcatgtccaccaatgggctgctgtgc
agcggccggggcaactgcgagtgcggcagctgtgtgtgcgtccagccaggctcctatgga
gacacctgtgagaagtgccccacctgcccagatgcctgctcctttaagaaggagtgtgtg
gagtgtaagaagttcaaccggggaacgctccatgaagaaaacacctgcagccgctactgc
cgggatgacatcgagcaggtgaaagagctgacggatactggcaaaaacgccgtgaattgt
acctacaagaacgaggatgactgtgtcgtcagattccagtactacgaagacaccagtggg
agggcagtcctctatgtggtggaagagcctgagtgtcccaagggtcctgatatcctggtg
gtcctgctgtcagtgatgggggccatcctgctcattggccttgctactctgctcatctgg
aagctactcatcactatccatgaccggaaggaatttgctaaatttgaggaagaacgagcc
agagccaagtgggacacagcaaacaacccgctgtataaagaggccacctccaccttcacc
aatatcacctaccgggggacttaa

DBGET integrated database retrieval system