KEGG   Mus musculus (mouse): 16419
Entry
16419             CDS       T01002                                 

Gene name
Itgb5, AA475909, AI874634, ESTM2, ESTM23, [b]-5, [b]5, [b]5A, [b]5B, beta-, beta-5, beta5
Definition
(RefSeq) integrin beta 5
  KO
K06588  integrin beta 5
Organism
mmu  Mus musculus (mouse)
Pathway
mmu04145  Phagosome
mmu04151  PI3K-Akt signaling pathway
mmu04510  Focal adhesion
mmu04512  ECM-receptor interaction
mmu04810  Regulation of actin cytoskeleton
mmu05165  Human papillomavirus infection
mmu05205  Proteoglycans in cancer
mmu05410  Hypertrophic cardiomyopathy
mmu05412  Arrhythmogenic right ventricular cardiomyopathy
mmu05414  Dilated cardiomyopathy
Brite
KEGG Orthology (KO) [BR:mmu00001]
 09130 Environmental Information Processing
  09132 Signal transduction
   04151 PI3K-Akt signaling pathway
    16419 (Itgb5)
  09133 Signaling molecules and interaction
   04512 ECM-receptor interaction
    16419 (Itgb5)
 09140 Cellular Processes
  09141 Transport and catabolism
   04145 Phagosome
    16419 (Itgb5)
  09144 Cellular community - eukaryotes
   04510 Focal adhesion
    16419 (Itgb5)
  09142 Cell motility
   04810 Regulation of actin cytoskeleton
    16419 (Itgb5)
 09160 Human Diseases
  09161 Cancer: overview
   05205 Proteoglycans in cancer
    16419 (Itgb5)
  09172 Infectious disease: viral
   05165 Human papillomavirus infection
    16419 (Itgb5)
  09166 Cardiovascular disease
   05410 Hypertrophic cardiomyopathy
    16419 (Itgb5)
   05412 Arrhythmogenic right ventricular cardiomyopathy
    16419 (Itgb5)
   05414 Dilated cardiomyopathy
    16419 (Itgb5)
 09180 Brite Hierarchies
  09182 Protein families: genetic information processing
   04131 Membrane trafficking [BR:mmu04131]
    16419 (Itgb5)
  09183 Protein families: signaling and cellular processes
   04515 Cell adhesion molecules [BR:mmu04515]
    16419 (Itgb5)
Membrane trafficking [BR:mmu04131]
 Endocytosis
  Phagocytosis
   Integrins (complement receptors)
    16419 (Itgb5)
Cell adhesion molecules [BR:mmu04515]
 Integrins
  Integrin beta subunits
   16419 (Itgb5)
SSDB
Motif
Pfam: Integrin_beta Integrin_B_tail Integrin_b_cyt PSI_integrin EGF_2 I-EGF_1
Other DBs
NCBI-GeneID: 16419
NCBI-ProteinID: NP_001139356
MGI: 96614
Ensembl: ENSMUSG00000022817
Vega: OTTMUSG00000028487
UniProt: O70309 Q6PE70
Position
16; 16 B3
AA seq 799 aa
MPRVPATLYACLLGLCALVPRLAGLNICTSGSATSCEECLLIHPKCAWCSKEYFGNPRSI
TSRCDLKANLIRNGCEGEIESPASSTHVLRNLPLSSKGSSATGSDVIQMTPQEIAVSLRP
GEQTTFQLQVRQVEDYPVDLYYLMDLSLSMKDDLENIRSLGTKLAEEMRKLTSNFRLGFG
SFVDKDISPFSYTAPRYQTNPCIGYKLFPNCVPSFGFRHLLPLTDRVDSFNEEVRKQRVS
RNRDAPEGGFDAVLQAAVCKEKIGWRKDALHLLVFTTDDVPHIALDGKLGGLVQPHDGQC
HLNEANEYTASNQMDYPSLALLGEKLAENNINLIFAVTKNHYMLYKNFTALIPGTTVEIL
HGDSKNIIQLIINAYSSIRAKVELSVWDQPEDLNLFFTATCQDGISYPGQRKCEGLKIGD
TASFEVSVEARSCPGRQAAQSFTLRPVGFRDSLQVEVAYNCTCGCSTGLEPNSARCSGNG
TYTCGLCECDPGYLGTRCECQEGENQSGYQNLCREAEGKPLCSGRGECSCNQCSCFESEF
GRIYGPFCECDSFSCARNKGVLCSGHGECHCGECKCHAGYIGDNCNCSTDVSTCRAKDGQ
ICSDRGRCVCGQCQCTEPGAFGETCEKCPTCPDACSSKRDCVECLLLHQGKPDNQTCHHQ
CKDEVITWVDTIVKDDQEAVLCFYKTAKDCVMMFSYTELPNGRSNLTVLREPECGSAPNA
MTILLAVVGSILLIGMALLAIWKLLVTIHDRREFAKFQSERSRARYEMASNPLYRKPIST
HTVDFAFNKFNKSYNGSVD
NT seq 2400 nt   +upstreamnt  +downstreamnt
atgccgcgggtgcccgcgaccctctacgcctgtctgctcgggctctgcgcgctcgttccg
cgcctcgcagggctcaacatatgcactagtggaagtgccacctcgtgtgaagaatgcctg
ttgatccacccaaaatgtgcctggtgctccaaagagtactttggcaatccacggtccatc
acctctcggtgtgacctgaaggcaaacctcatccggaatggctgtgaaggtgagattgag
agtccagccagcagcacccacgtcctccggaacctacctctcagcagcaagggttccagt
gccacgggctctgacgtcatccagatgacgccgcaggagattgcagtgagcctccggcca
ggcgagcagactacgttccagctgcaggtgcgccaggtggaggactaccctgtagacctg
tactacctgatggacctctccctctccatgaaggatgacttggagaacatccggagcctg
ggcaccaagcttgcggaggaaatgaggaagctcactagtaacttccgcttaggtttcggg
tcttttgttgacaaggacatctctcctttctcctacacggcaccgagataccagaccaat
ccgtgtattggttacaagttattccccaactgcgtcccctccttcgggttccggcatctg
ctgcctctcacagacagagtcgacagcttcaacgaggaagtgaggaagcagagggtgtcc
cggaaccgagatgcccccgagggggggtttgatgcggtcctccaggctgctgtctgcaag
gagaagatcggatggcgaaaagatgctctgcacttgctggtgttcacaacagacgatgtg
ccccacatcgcactggatggaaaactgggtggcctggtccagccccacgatggccagtgt
cacctgaatgaagccaatgagtacacagcctctaaccagatggactatccatcgcttgcc
ttgcttggggagaagctggcagagaacaatatcaacctcatttttgctgtgacgaagaac
cactatatgctctacaagaattttacagccctgatacctggaaccactgtggagattttg
catggagattccaaaaatattattcaactgattatcaatgcgtacagtagcatccgggct
aaagtggagctgtcagtgtgggatcagccagaagaccttaatctcttcttcactgccacc
tgccaagatggcatatcttaccctggtcagaggaagtgtgagggtctgaagattggggac
acggcatcctttgaagtgtccgtggaggctcggagctgccccggcagacaagcagcacag
tctttcaccttgaggcccgtgggcttccgggacagtctgcaggtggaagtcgcctacaat
tgcacatgcggctgtagcacggggctggagcccaacagtgccagatgcagtgggaatgga
acatacacctgtgggctgtgcgagtgtgaccccggctacctgggcactaggtgcgagtgc
caggagggggagaaccagagcgggtaccagaacctgtgccgggaggcagagggcaagcct
ctgtgcagcgggcgtggagagtgtagctgcaaccagtgctcctgcttcgagagtgagttc
gggaggatctacggacctttctgcgagtgtgacagcttttcctgtgccagaaacaagggc
gtcctatgctcaggccatggagagtgtcactgtggagaatgcaaatgccacgcaggttac
attggggacaattgtaactgctcaacagacgtcagcacatgcagggccaaggatgggcag
atctgcagtgaccgaggccgttgtgtctgtgggcagtgccagtgcacagagcctggagcc
tttggggagacgtgtgagaagtgcccaacctgcccggatgcttgcagctctaagagagac
tgtgtcgaatgcttgctacttcaccaggggaaacctgacaaccagacctgccaccaccag
tgcaaagatgaggtgatcacgtgggtagacaccatcgtcaaagatgaccaggaggctgtg
ctttgcttctacaaaactgctaaggactgcgttatgatgttcagctacacagaactgccc
aatgggaggtccaacttgacggtcctccgggagccagaatgtggaagtgcccccaatgcc
atgaccatcctgctggctgtggttggcagcatcctcctgattgggatggcactcctggcc
atctggaagctgctcgtcaccatccacgaccgccgagagtttgccaagttccaaagtgag
cgctccagggcccgttatgaaatggcctcaaaccccctgtacagaaagcccatctccaca
cacactgtcgatttcgccttcaacaagttcaacaaatcctacaatggctcagtggactga

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