KEGG   Mus musculus (house mouse): 16428
Entry
16428             CDS       T01002                                 
Symbol
Itk, Emt, Tcsk, Tsk
Name
(RefSeq) IL2 inducible T cell kinase
  KO
K07363  IL2-inducible T-cell kinase [EC:2.7.10.2]
Organism
mmu  Mus musculus (house mouse)
Pathway
mmu04062  Chemokine signaling pathway
mmu04660  T cell receptor signaling pathway
mmu04670  Leukocyte transendothelial migration
Brite
KEGG Orthology (KO) [BR:mmu00001]
 09150 Organismal Systems
  09151 Immune system
   04660 T cell receptor signaling pathway
    16428 (Itk)
   04670 Leukocyte transendothelial migration
    16428 (Itk)
   04062 Chemokine signaling pathway
    16428 (Itk)
 09180 Brite Hierarchies
  09181 Protein families: metabolism
   01001 Protein kinases [BR:mmu01001]
    16428 (Itk)
Enzymes [BR:mmu01000]
 2. Transferases
  2.7  Transferring phosphorus-containing groups
   2.7.10  Protein-tyrosine kinases
    2.7.10.2  non-specific protein-tyrosine kinase
     16428 (Itk)
Protein kinases [BR:mmu01001]
 Non-receptor tyrosine kinases
  TEC family
   16428 (Itk)
SSDB
Motif
Pfam: PK_Tyr_Ser-Thr Pkinase SH2 PH SH3_1 BTK SH3_9 SH3_10 SH3_2 SH3_3 ABC1 PH_8 SH3_4
Other DBs
NCBI-GeneID: 16428
NCBI-ProteinID: NP_001268894
MGI: 96621
Ensembl: ENSMUSG00000020395
UniProt: Q03526 Q3U5G1
Structure
Position
11:complement(46215975..46280342)
AA seq 625 aa
MNNFILLEEQLIKKSQQKRRTSPSNFKVRFFVLTKASLAYFEDRHGKKRTLKGSIELSRI
KCVEIVKSDISIPCHYKYPFQTLVYLQVVHDNYLLYVFAPDCESRQRWVLTLKEETRNNN
SLVSKYHPNFWMDGRWRCCSQLEKPAVGCAPYDPSKNASKKPLPPTPEDNRRSFQEPEET
LVIALYDYQTNDPQELALRCDEEYYLLDSSEIHWWRVQDKNGHEGYAPSSYLVEKSPNNL
ETYEWYNKSISRDKAEKLLLDTGKEGAFMVRDSRTPGTYTVSVFTKAIISENPCIKHYHI
KETNDSPKRYYVAEKYVFDSIPLLIQYHQYNGGGLVTRLRYPVCSWRQKAPVTAGLRYGK
WVIQPSELTFVQEIGSGQFGLVHLGYWLNKDKVAIKTIQEGAMSEEDFIEEAEVMMKLSH
PKLVQLYGVCLEQAPICLVFEFMEHGCLSDYLRSQRGLFAAETLLGMCLDVCEGMAYLEK
ACVIHRDLAARNCLVGENQVIKVSDFGMTRFVLDDQYTSSTGTKFPVKWASPEVFSFSRY
SSKSDVWSFGVLMWEVFSEGKIPYENRSNSEVVEDISTGFRLYKPRLASCHVYQIMNHCW
KEKPEDRPPFSQLLSQLAEIAEAGL
NT seq 1878 nt   +upstreamnt  +downstreamnt
atgaacaacttcatcctcctggaagaacagctgatcaagaagtcccaacagaagagaagg
acttctccctcgaattttaaagttcgtttctttgtcttaacgaaagccagcctggcctac
tttgaggaccgccacgggaagaagcgcacgttgaagggctccattgaactctccagaatc
aagtgtgtggagattgtcaagagtgacattagcatcccgtgccactataaataccctttt
cagactcttgtgtacttacaggtcgtgcatgacaactatctcctgtatgtgtttgctcca
gactgtgagagtcggcagcgctgggtgctgacccttaaagaagaaacgaggaataacaac
agcctggtatccaagtatcaccctaatttctggatggatgggcggtggaggtgctgctcc
cagctggagaagcctgctgtaggctgtgctccctacgacccatccaagaatgcttcaaag
aagcctcttcctcctactcctgaagacaacaggcggtcatttcaggaacctgaagaaacc
ctggtcattgccttgtacgactaccaaaccaacgaccctcaggagctcgcactgcggtgt
gatgaagagtactacctgctggacagctccgagatccactggtggagggttcaagacaaa
aatgggcatgaaggatatgcaccaagcagttacctggtagaaaaatctccaaataacctt
gaaacctatgagtggtacaataaaagcatcagccgcgacaaagctgaaaaacttcttttg
gacacaggtaaagaaggagctttcatggtccgagattccaggacacccgggacatacaca
gtctctgttttcaccaaggccatcataagtgagaacccctgtataaaacattatcacatc
aaagaaacaaatgacagccccaagcgctactacgtggctgagaagtatgtgtttgactcc
atccctctcctcatccagtatcaccagtacaatggaggaggtttggtcactcgactccgc
tatccagtttgctcctggagacaaaaagcccctgtcacagcagggctaagatatgggaag
tgggtgatccaaccctcagagctaacgttcgtgcaggagattggcagcgggcagtttggg
ctggtgcatctcggctactggctcaacaaggacaaggtggccatcaagaccattcaggaa
ggggcgatgtcagaagaagactttatcgaggaggcggaagtcatgatgaaactctctcac
cccaaactggtgcagctctatggggtgtgcctggagcaagcccccatctgcctggtgttt
gagttcatggagcacggctgcctgtcggattaccttcgaagtcagcggggtctctttgct
gcggagaccctgctgggcatgtgcctggatgtgtgtgagggcatggcctacctggaaaaa
gcttgtgtcatccacagagacctggcagccagaaactgtttggtgggagaaaaccaggtc
atcaaggtgtccgactttgggatgacaagatttgtccttgatgatcaatataccagctcc
acgggcaccaaattcccagtgaagtgggcatccccagaggtgttctcctttagtcgctat
agcagcaagtcagatgtgtggtcgtttggtgtactgatgtgggaagtcttcagtgaaggc
aaaatcccatacgaaaaccgaagcaattccgaggtcgtggaagatatcagcactggcttt
cggttatacaagccccgcctggcctcctgtcatgtctaccagatcatgaatcattgctgg
aaagagaaaccagaagaccggccacccttctcccagctgttaagccagctggctgaaatc
gcagaagctgggctttag

  All links  
Gene (14)   
   RefGene (9)   
   NCBI-PROTEINID (1)   
   NCBI-Gene (1)   
   Ensembl (1)   
   RIKEN BRC-DNA (1)   
   OC (1)   
Protein sequence (8)   
   UniProt (2)   
   SWISS-PROT (1)   
   RefSeq(pep) (5)   
DNA sequence (37)   
   RefSeq(nuc) (5)   
   GenBank (16)   
   EMBL (16)   
3D Structure (12)   
   PDB (12)   
Protein domain (13)   
   Pfam (13)   
All databases (84)   

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