| Entry |
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| Symbol |
Kit, Bs, CD117, Fdc, Gsfsco1, Gsfsco5, Gsfsow3, SCO1, SCO5, SOW3, Ssm, Tr-kit, W, c-KIT
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| Name |
(RefSeq) KIT proto-oncogene receptor tyrosine kinase
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| KO |
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| Organism |
mmu Mus musculus (house mouse)
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| Pathway |
| mmu04072 | Phospholipase D signaling pathway |
| mmu05230 | Central carbon metabolism in cancer |
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| Brite |
KEGG Orthology (KO) [BR:mmu00001]
09130 Environmental Information Processing
09132 Signal transduction
04010 MAPK signaling pathway
16590 (Kit)
04014 Ras signaling pathway
16590 (Kit)
04015 Rap1 signaling pathway
16590 (Kit)
04072 Phospholipase D signaling pathway
16590 (Kit)
04151 PI3K-Akt signaling pathway
16590 (Kit)
09150 Organismal Systems
09151 Immune system
04640 Hematopoietic cell lineage
16590 (Kit)
09152 Endocrine system
04916 Melanogenesis
16590 (Kit)
09160 Human Diseases
09161 Cancer: overview
05200 Pathways in cancer
16590 (Kit)
05230 Central carbon metabolism in cancer
16590 (Kit)
09162 Cancer: specific types
05221 Acute myeloid leukemia
16590 (Kit)
05224 Breast cancer
16590 (Kit)
09180 Brite Hierarchies
09181 Protein families: metabolism
01001 Protein kinases [BR:mmu01001]
16590 (Kit)
09183 Protein families: signaling and cellular processes
04090 CD molecules [BR:mmu04090]
16590 (Kit)
Enzymes [BR:mmu01000]
2. Transferases
2.7 Transferring phosphorus-containing groups
2.7.10 Protein-tyrosine kinases
2.7.10.1 receptor protein-tyrosine kinase
16590 (Kit)
Protein kinases [BR:mmu01001]
Receptor tyrosine kinases (RTK)
PDGFR family [OT]
16590 (Kit)
CD molecules [BR:mmu04090]
Proteins
16590 (Kit)
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| SSDB |
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| Motif |
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| Other DBs |
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| Structure |
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| Position |
5:75735647..75817382
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| AA seq |
979 aa
MRGARGAWDLLCVLLVLLRGQTATSQPSASPGEPSPPSIHPAQSELIVEAGDTLSLTCID
PDFVRWTFKTYFNEMVENKKNEWIQEKAEATRTGTYTCSNSNGLTSSIYVFVRDPAKLFL
VGLPLFGKEDSDALVRCPLTDPQVSNYSLIECDGKSLPTDLTFVPNPKAGITIKNVKRAY
HRLCVRCAAQRDGTWLHSDKFTLKVRAAIKAIPVVSVPETSHLLKKGDTFTVVCTIKDVS
TSVNSMWLKMNPQPQHIAQVKHNSWHRGDFNYERQETLTISSARVDDSGVFMCYANNTFG
SANVTTTLKVVEKGFINISPVKNTTVFVTDGENVDLVVEYEAYPKPEHQQWIYMNRTSAN
KGKDYVKSDNKSNIRYVNQLRLTRLKGTEGGTYTFLVSNSDASASVTFNVYVNTKPEILT
YDRLINGMLQCVAEGFPEPTIDWYFCTGAEQRCTTPVSPVDVQVQNVSVSPFGKLVVQSS
IDSSVFRHNGTVECKASNDVGKSSAFFNFAFKGNNKEQIQAHTLFTPLLIGFVVAAGAMG
IIVMVLTYKYLQKPMYEVQWKVVEEINGNNYVYIDPTQLPYDHKWEFPRNRLSFGKTLGA
GAFGKVVEATAYGLIKSDAAMTVAVKMLKPSAHLTEREALMSELKVLSYLGNHMNIVNLL
GACTVGGPTLVITEYCCYGDLLNFLRRKRDSFIFSKQEEQAEAALYKNLLHSTEPSCDSS
NEYMDMKPGVSYVVPTKTDKRRSARIDSYIERDVTPAIMEDDELALDLDDLLSFSYQVAK
GMAFLASKNCIHRDLAARNILLTHGRITKICDFGLARDIRNDSNYVVKGNARLPVKWMAP
ESIFSCVYTFESDVWSYGIFLWELFSLGSSPYPGMPVDSKFYKMIKEGFRMVSPEHAPAE
MYDVMKTCWDADPLKRPTFKQVVQLIEKQISDSTKHIYSNLANCNPNPENPVVVDHSVRV
NSVGSSASSTQPLLVHEDA |
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| NT seq |
2940 nt +upstreamnt +downstreamnt
atgagaggcgctcgcggcgcctgggatctgctctgcgtcctgttggtcctgctccgtggc
cagacagccacgtctcagccatctgcaagtccaggggagccgtctccgccatccatccat
ccagcacaatcagagttaatagttgaagctggcgacaccctcagcctgacgtgcattgat
cccgactttgtcagatggactttcaagacctatttcaatgaaatggttgagaataaaaaa
aatgaatggatccaggaaaaagccgaggccactcgcacgggcacatacacgtgcagcaac
agcaatggcctcacgagttctatttacgtgtttgttagagatcctgccaaacttttcctg
gttggccttcccttgtttggcaaagaagacagcgacgcgctggtccgctgccctctgaca
gacccacaggtgtccaattattccctcatcgagtgtgatgggaaatctctccccacggac
ctgacgtttgtcccaaaccccaaggctggcatcaccatcaaaaacgtgaagcgcgcctac
caccggctctgtgtccgctgtgctgctcagcgtgacggtacatggctgcattctgacaaa
ttcaccctcaaagtgcgggcagccatcaaggctatccctgttgtgtctgtgcctgaaaca
agtcacctccttaagaaaggggacacatttacggtggtgtgcaccataaaagatgtgtct
acatccgtgaactccatgtggctaaagatgaaccctcagcctcagcacatagcccaggta
aagcacaatagctggcaccggggtgacttcaattatgaacgccaggagacgctgactatc
agctcggcaagagttgacgattctggagtgttcatgtgttatgccaataatacttttgga
tcagcaaatgtcacaacaaccttgaaagtagtagaaaaaggattcatcaacatctcccct
gtgaagaacactacagtatttgtaaccgatggagaaaacgtagatttggttgttgaatac
gaggcctaccccaaacccgagcaccagcagtggatatatatgaacaggacctcggctaac
aaagggaaggattatgtcaaatctgataacaaaagcaacatcagatatgtgaaccaactt
cgcctgaccagattaaaaggcacagaaggaggcacttatacctttctggtgtccaactct
gatgccagtgcttccgtgacattcaacgtttacgtgaacacaaaaccagaaatcctgacg
tacgacaggctcataaatggcatgctccagtgtgtggcagagggattcccggagcccaca
atagattggtatttttgtacaggagcagagcaaaggtgtaccactcctgtctcaccagtg
gacgtacaggtccagaatgtatctgtgtcaccatttggaaaactggtggttcagagttcc
atagactccagcgtcttccggcacaacggcacggtggagtgtaaggcctccaacgatgtg
ggcaagagttccgccttctttaactttgcatttaaaggtaacaacaaagagcaaatccag
gcccacactctgttcacgccgctgctcattggctttgtggttgcagctggcgcgatgggg
atcattgtgatggtgctcacctacaaatatttgcagaaacccatgtatgaagtacaatgg
aaggttgtcgaggagataaatggaaacaattatgtttacatagacccgacgcaacttcct
tatgatcacaaatgggagtttcccagaaacaggctgagttttggaaagacattgggagct
ggtgccttcgggaaggtcgttgaggccactgcatatggcttgattaagtcggatgctgcc
atgacagttgccgtgaagatgctcaaaccaagtgcccatttaacagaaagagaggcccta
atgtcggaactgaaggtcctgagctacctgggcaatcacatgaatattgtgaacctgctt
ggcgcatgcacggtgggagggcccaccctggtcattacagaatattgttgctatggtgat
cttttgaattttttgagaaggaagcgtgactcgtttattttctcaaagcaagaagagcag
gcagaagcggcactttataagaaccttctgcactcaacggagccttcctgtgacagttca
aatgaatatatggacatgaagcctggcgtttcctacgtggtgccaaccaagacagacaag
aggagatccgcaagaatagactcgtacatagaaagagacgtgactcctgccatcatggaa
gatgacgagctggctctggacctggatgatttgctgagcttctcctaccaggtggccaag
ggcatggcgttcctcgcctccaagaattgtattcacagagatttggcagccaggaatatc
ctcctcactcacgggcggatcacaaagatttgcgatttcgggctagccagagacatcagg
aatgattcgaattacgtggtcaaaggaaatgcacgactgcccgtgaagtggatggcacca
gagagcattttcagctgcgtgtacacatttgaaagtgatgtctggtcctatgggattttc
ctctgggagctcttctccttaggaagcagcccctacccagggatgccggtcgactccaag
ttctacaagatgatcaaggaaggcttccggatggtcagcccggagcacgcgcctgccgaa
atgtatgacgtcatgaagacttgctgggacgctgaccccttgaaaaggccaacattcaag
caggttgtccaacttattgagaagcagatctcggacagcaccaagcacatttactccaac
ttggcaaactgcaaccccaacccagagaaccccgtggtggtggaccattccgtgagggtc
aactcggtgggcagcagcgcctcttctacgcagcccctgctcgtgcacgaagatgcctga |
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