KEGG   Mus musculus (house mouse): 16800
Entry
16800             CDS       T01002                                 
Symbol
Arhgef2, GEF, GEF-H1, GEFH1, LFP40, Lbcl1, Lfc, P40, mKIAA0651
Name
(RefSeq) Rho/Rac guanine nucleotide exchange factor 2
  KO
K12791  Rho guanine nucleotide exchange factor 2
Organism
mmu  Mus musculus (house mouse)
Pathway
mmu04530  Tight junction
mmu05418  Fluid shear stress and atherosclerosis
Brite
KEGG Orthology (KO) [BR:mmu00001]
 09140 Cellular Processes
  09144 Cellular community - eukaryotes
   04530 Tight junction
    16800 (Arhgef2)
 09160 Human Diseases
  09166 Cardiovascular disease
   05418 Fluid shear stress and atherosclerosis
    16800 (Arhgef2)
 09180 Brite Hierarchies
  09182 Protein families: genetic information processing
   04131 Membrane trafficking [BR:mmu04131]
    16800 (Arhgef2)
Membrane trafficking [BR:mmu04131]
 Others
  Rho GTPase associated proteins
   Rho guanine nucleotide exchange factors (GEFs)
    16800 (Arhgef2)
SSDB
Motif
Pfam: PH_16 RhoGEF PH C1_1 C1_2 Crescentin Prok-RING_1 TrbK zinc_ribbon_9 PHD ACP_PD
Other DBs
NCBI-GeneID: 16800
NCBI-ProteinID: NP_032513
MGI: 103264
Ensembl: ENSMUSG00000028059
UniProt: Q60875
Structure
Position
3:88500427..88556839
AA seq 985 aa
MSRIESLTRARIDRSKEQATKTREKEKMKEAKDARYTNGHLFTTISVSGMTMCYACNKSI
TAKEALICPTCNVTIHNRCKDTLANCTKVKQKQQKAALLRNNTALQSVSLRSKTTTRERP
TSAIYPSDSFRQSLLGSRRGLSSLSLAKSVSTTNIAGHFNDESPLGLRQILSQSTDSLNM
RNRTLSVESLIDEGVEVFYNELMSDFEMDEKDFEADSWSLAVDSSFLQQHKKEVMKKQDV
IYELIQTELHHVRTLKIMTRLFRTGMLEELQMEPEVVQGLFPCVDELSDIHTRFLNQLLE
RRRQALCPGSTRNFVIHRLGDLLISQFSGSNAEQMRKTYSEFCSRHTKALKLYKELYARD
KRFQQFIRKMTRSAVLKRHGVQECILLVTQRITKYPVLINRILQNSHGVEEEYQDLASAL
GLVKELLSNVDQDVHELEKEARLQEIYNRMDPRAQTPVPGKGPFGRDELLRRKLIHEGCL
LWKTATGRFKDVLLLLMTDVLVFLQEKDQKYIFTSLDKPSVVSLQNLIVRDIANQAKGMF
LISSGPPEMYEVHAASRDDRTTWIRVIQQSVRLCPSREDFPLIETEDKAYLRRIKTKLQQ
KNQALVELLQKNVELFAEMVHFQALKAGFVGMPPPALPRGLFRLESFESLRGERLLKDAL
REVEGLKDLLLGPCVDLPMTSREPALPLDSDSGSCPGVTANGEARTFNGSIELCRADSDS
SQKDRNGNQLRSPQEEVLQPLINLYGLLHGLQAVVVQQERLMEALFPEGPERWEKLSRAN
SRDGEAGRAAVASVTPEKQATELALLQRQHTLLQEELRRCQRLGEERATEAGSLEARLRE
SEQARALLEREAEEIRRQLAALGQNEPLPAEAPWARRPLDPRRRSLPAGDALYLSFNPPQ
PSRGHDRLDLPVTVRSLHRPFDDREAQELGSPEDRLQDSSDPDTGSEEEVSSRLSPPHSP
RDFTRMQDIPEETESRDGEPTASES
NT seq 2958 nt   +upstreamnt  +downstreamnt
atgtctcggatcgaatccctcactcgcgcgcggatcgaccggagcaaggagcaggcaacc
aagacccgggaaaaggagaagatgaaggaagctaaagatgcccgctataccaacggccac
ctcttcaccaccatctccgtctccggcatgaccatgtgctatgcctgtaacaagagcatc
acagccaaggaagccctcatttgtcctacatgtaacgtgaccatccacaaccgctgtaaa
gacaccctggccaactgtaccaaggtcaagcagaagcaacagaaagctgcactgctgagg
aacaacactgctttgcagtctgtctcccttcgaagtaagacgaccaccagagagcggcca
acgtctgccatttacccttccgacagcttccggcagtccctcctgggttctcggcggggc
ctctcctccttatctttggccaaaagtgtttccactaccaacattgctggacatttcaat
gatgagtctcctctggggctgcgtcagatcctctcccagtccacagactccctcaacatg
cggaaccgaaccctgtccgtggaatcccttattgatgaaggtgtagaagtgttctacaat
gagctgatgagcgactttgagatggatgagaaggactttgaggcggattcttggagcctt
gccgtggacagcagcttcctgcagcagcacaaaaaggaagtgatgaagaagcaagatgtc
atctatgagctgatccagacagagctgcaccacgtgagaaccttgaagattatgacccgc
ctctttcgcactgggatgctggaagagttgcagatggagccagaagtggtccagggcctg
ttcccctgcgtggatgaactcagtgacattcacacacgtttccttaatcagcttctggaa
cggcggcgccaggctctatgtccaggcagcacccggaactttgtcatccatcgtttgggt
gacttgctcatcagtcagttctcaggttccaatgctgagcagatgcgcaagacctactca
gagttctgcagccgccacaccaaggccttaaagctctataaggagctgtatgctcgagac
aaacgcttccaacagttcatccggaaaatgacccgctcagctgtgttgaagcggcatgga
gttcaggaatgcattctcctggtgactcagcggatcaccaaataccctgtgctcatcaac
agaatcctgcagaattcccacggggttgaagaagagtaccaagacttggcgtcagcccta
ggactagtgaaggagttgttgtccaatgtggaccaggatgtgcacgagctggagaaagag
gcccgcctgcaggagatttacaaccgaatggatccccgggctcagacccccgtacctggc
aagggccccttcggccgagatgaacttttacggagaaaacttatccatgaaggctgcctg
ctctggaagacagccacaggccgcttcaaagatgtcctgttgctgctgatgacagatgtg
ctcgtgtttctccaggaaaaggaccagaaatacattttcacgtctctggacaagccctca
gtggtgtccttgcagaacctcatcgtaagagacatagccaaccaggcgaaagggatgttt
ctgattagttctggaccgcctgagatgtatgaggtgcatgcagcgtcccgagacgaccgg
actacctggatccgtgtcatccagcagagtgtgcgcctgtgcccgtccagggaggacttt
cctctgatcgagacagaggataaggcgtatctccggaggatcaagacgaaactgcagcag
aaaaaccaggcgctagtggagctgctacagaagaatgttgagctgtttgccgagatggtc
cacttccaggccttaaaggctggcttcgttggaatgcccccacccgccctgcccaggggc
cttttccgtcttgagtcctttgagtccctccgaggcgagcgcctgctaaaggatgccctc
cgtgaagtggaaggcctgaaagacctgctgttgggcccatgtgtggacctgcctatgaca
tcccgagaaccagccttacccttggactctgacagcggtagctgtcctggggtcactgcc
aatggagaggccagaaccttcaatggctccattgaactctgtagagcagactcggattcc
agccagaaggatcggaatggaaatcagttgagatcaccacaggaggaggtgttacagcca
ttgatcaatctttatggacttctacatggcctgcaggctgttgtggtccagcaggaaaga
ctgatggaagccctgttccctgagggccctgaacggtgggaaaagctatcccgagccaac
tctcgggatggtgaagctggccgggctgcggttgcttctgtaactcctgagaagcaggcc
acggagctggcactactgcagaggcaacacaccctgttgcaggaagagctgcggcgctgc
cagcggctcggggaagagcgggcaactgaagctggcagcctggaggccaggctccgagag
agcgagcaagcccgggccctgctggagcgggaggctgaagagatccgccggcagcttgca
gccttgggccaaaacgagccactcccggcagaagcgccctgggctcgcaggcctctggac
ccacggcgccgcagccttccagcgggcgacgctttatacttgagcttcaatcccccccag
cccagtcgaggccatgaccgcctggatttgcctgtgactgttcgttccctccaccgaccc
tttgatgaccgagaggcgcaagaacttggtagccccgaggatcgactacaggacagcagt
gaccctgatactggtagtgaggaggaagtcagtagccgcctgtctccacctcacagtcct
cgagacttcacccgaatgcaggacattcctgaagagacagaaagccgagatggggagccc
acagcttcagagagctaa

  All links  
Ontology (2)   
   KEGG BRITE (2)   
Pathway (2)   
   KEGG PATHWAY (2)   
Genome (1)   
   KEGG GENOME (1)   
Gene (20)   
   KEGG ORTHOLOGY (1)   
   KEGG GENES (1)   
   RefGene (13)   
   NCBI-PROTEINID (1)   
   NCBI-Gene (1)   
   Ensembl (1)   
   RIKEN BRC-DNA (1)   
   OC (1)   
Protein sequence (19)   
   UniProt (1)   
   SWISS-PROT (1)   
   RefSeq(pep) (17)   
DNA sequence (61)   
   RefSeq(nuc) (17)   
   GenBank (22)   
   EMBL (22)   
3D Structure (1)   
   PDB (1)   
Protein domain (11)   
   Pfam (11)   
All databases (117)   

Download RDF
DBGET integrated database retrieval system