KEGG   Mus musculus (mouse): 16881
Entry
16881             CDS       T01002                                 

Gene name
Lig1, AL033288, L, LigI, mL
Definition
(RefSeq) ligase I, DNA, ATP-dependent
  KO
K10747  DNA ligase 1 [EC:6.5.1.1 6.5.1.6 6.5.1.7]
Organism
mmu  Mus musculus (mouse)
Pathway
mmu03030  DNA replication
mmu03410  Base excision repair
mmu03420  Nucleotide excision repair
mmu03430  Mismatch repair
Brite
KEGG Orthology (KO) [BR:mmu00001]
 09120 Genetic Information Processing
  09124 Replication and repair
   03030 DNA replication
    16881 (Lig1)
   03410 Base excision repair
    16881 (Lig1)
   03420 Nucleotide excision repair
    16881 (Lig1)
   03430 Mismatch repair
    16881 (Lig1)
 09180 Brite Hierarchies
  09182 Protein families: genetic information processing
   03032 DNA replication proteins [BR:mmu03032]
    16881 (Lig1)
   03400 DNA repair and recombination proteins [BR:mmu03400]
    16881 (Lig1)
Enzymes [BR:mmu01000]
 6. Ligases
  6.5  Forming phosphoric-ester bonds
   6.5.1  Ligases that form phosphoric-ester bonds (only sub-subclass identified to date)
    6.5.1.1  DNA ligase (ATP)
     16881 (Lig1)
    6.5.1.6  DNA ligase (ATP or NAD+)
     16881 (Lig1)
    6.5.1.7  DNA ligase (ATP, ADP or GTP)
     16881 (Lig1)
DNA replication proteins [BR:mmu03032]
 Eukaryotic type
  DNA Replication Elongation Factors
   Other elongation factors
    16881 (Lig1)
 Prokaryotic type
   Elongation factors (archaeal)
    Other elongation factors
     16881 (Lig1)
DNA repair and recombination proteins [BR:mmu03400]
 Eukaryotic type
  SSBR (single strand breaks repair)
   BER (base exicision repair)
    Long Patch-BER factors
     16881 (Lig1)
   NER (nucleotide excision repair)
    Other NER factors
     16881 (Lig1)
   MMR (mismatch excision repair)
    Other MMR factors
     16881 (Lig1)
SSDB
Motif
Pfam: DNA_ligase_A_M DNA_ligase_A_N DNA_ligase_A_C DDR PucR
Other DBs
NCBI-GeneID: 16881
NCBI-ProteinID: NP_034845
MGI: 101789
Ensembl: ENSMUSG00000056394
UniProt: P37913 Q3U4X8 Q8R055 Q3TSU8
Position
7 A1; 7 7.82 cM
AA seq 916 aa
MQRSIMSFFQPTKEGKAKKPEKETPSSIREKEPPPKVALKERNQVVPESDSPVKRTGRKV
AQVLSCEGEDEDEAPGTPKVQKPVSDSEQSSPPSPDTCPENSPVFNCSSPMDISPSGFPK
RRTARKQLPKRTIQDTLEEQNEDKTKTAKKRKKEEETPKESLAEAEDVKQKEEKEGDQLI
VPSEPTKSPESVTLTKTENIPVCKAGVKLKPQEEEQSKPPARGAKTLSSFFTPRKPAVKT
EVKQEESGTLRKEETKGTLDPANYNPSKNNYHPIEDACWKHGQKVPFLAVARTFEKIEEV
SARLKMVETLSNLLRSVVALSPPDLLPVLYLSLNRLGPPQQGLELGVGDGVLLKAVAQAT
GRQLESIRAEVAEKGDVGLVAENSRSTQRLMLPPPPLTISGVFTKFCDIARLTGSASMAK
KMDIIKGLFVACRHSEARYIARSLSGRLRLGLAEQSVLAALAQAVSLTPPGQEFPTAVVD
AGKGKTAEARKMWLEEQGMILKQTFCEVPDLDRIIPVLLEHGLERLPEHCKLSPGVPLKP
MLAHPTRGVSEVLKRFEEVDFTCEYKYDGQRAQIHVLEGGEVKIFSRNQEDNTGKYPDII
SRIPKIKHPSVTSFILDTEAVAWDREKKQIQPFQVLTTRKRKEVDASEIQVQVCLYAFDL
IYLNGESLVRQPLSRRRQLLRENFVETEGEFVFTTSLDTKDTEQIAEFLEQSVKDSCEGL
MVKTLDVDATYEIAKRSHNWLKLKKDYLDGVGDTLDLVVIGAYLGRGKRAGRYGGFLLAA
YDEESEELQAICKLGTGFSDEELEEHHQSLQALVLPTPRPYVRIDGAVAPDHWLDPSIVW
EVKCADLSLSPIYPAARGLVDKEKGISLRFPRFIRVRKDKQPEQATTSNQVASLYRKQSQ
IQNQQSSDLDSDVEDY
NT seq 2751 nt   +upstreamnt  +downstreamnt
atgcagagaagtattatgtcattttttcaacccacaaaagaaggtaaagcgaagaagcca
gagaaggagacacccagcagcatcagagagaaggaaccccctccaaaggtggcgctgaag
gagaggaatcaagtggtgcccgagagtgattctccagtgaagaggacaggaaggaaggta
gcccaggttctgagctgtgaaggggaggacgaagatgaagcccctggcacccccaaagtc
cagaagcctgtgtcagactctgaacagagctctcctcccagccctgacacatgtcctgag
aacagtcctgtcttcaactgcagctcccccatggacatctccccatcaggattcccaaag
cgtcgaactgcgcggaagcagctccccaaacggacaattcaagacactcttgaggagcag
aatgaggacaaaaccaaaacagctaagaaaaggaagaaagaagaagagaccccaaaagaa
agcctcgcagaggctgaagacgtaaaacagaaggaagaaaaggagggggaccagctcata
gtcccctctgagcccacaaagtcccctgagtcagtaaccctgacaaagacagagaacatt
ccagtgtgtaaggcaggagtgaaactgaagcctcaggaagaggaacagagcaaacctcct
gctagaggtgccaagacactgagcagtttcttcacaccccgaaaaccagcagtgaaaact
gaagtcaaacaagaagagtcaggcactctaaggaaggaagagaccaagggaaccctggat
ccagcaaattataatccttccaagaataactatcatcccattgaagatgcctgctggaaa
catggccagaaggtcccttttctcgccgtggcccggacatttgagaagattgaggaggtt
tctgctaggctcaagatggtggagacattgagcaacctgctgcgctccgtggtggccctg
tcccctccagacttgctccctgttctctatctcagcctcaaccgcctcgggccacctcag
cagggactagagctgggtgttggtgatggtgtcctcctcaaggccgttgcccaggccaca
ggtcgtcagctggagtccatccgggctgaggtagctgagaagggggatgtggggctggtg
gccgagaacagccgcagcactcagagactcatgctgcctccacctccacttactatttct
ggagtcttcaccaaattctgtgacattgcccggctcactggcagtgcttccatggccaag
aagatggacattatcaagggcctttttgttgcctgccgccactcagaagccaggtacatt
gccaggtccctaagcgggcggctgcgccttggcctagctgagcagtcggtactggctgct
cttgcccaggctgtgagcctcacaccccctggccaagaatttcccacggcggtggtggat
gctgggaagggcaagacagcagaggccagaaagatgtggttggaagaacaaggcatgatc
ttgaagcagaccttctgtgaggttcctgacctggatcgaatcatccctgtgctgctggaa
catggcctggaacgtctcccagagcactgcaagctgagcccaggggtccctcttaaacca
atgctggctcatcccactcggggtgtcagtgaggtcctaaaacgctttgaggaggtcgac
ttcacctgtgaatataaatacgatgggcagcgagcacagatacatgttctggaaggtgga
gaagtgaagatcttcagcaggaaccaggaagacaacacaggaaagtatcctgacattatc
agccgcatccccaagattaaacacccctcagtcacatctttcattctggacactgaggct
gtggcctgggaccgggaaaagaagcagatccaaccattccaagtactcaccacgcgcaag
cgcaaggaggttgatgcatcggagatacaggtgcaagtgtgtctgtatgcttttgacctc
atctacctcaacggagagtccctggttcgccagcccctgtctcgacgccggcagctgctc
cgtgagaacttcgtggagacagagggtgagtttgtcttcaccacctctttggacaccaag
gacaccgagcagattgctgagttcttggagcagtcagtgaaggactcctgtgagggcctg
atggtgaagaccttggatgttgatgccacttatgagattgccaagaggtcacacaactgg
ctcaagctgaagaaggactaccttgacggtgtgggtgacactctggaccttgtggtgatt
ggtgcctacctgggccgggggaagcgggctggccggtatggaggcttcctgttggctgcc
tacgatgaggagagtgaagagcttcaggctatatgcaagctgggaactggattcagcgat
gaggagctggaggaacaccaccagagcctgcaggccctggtattgcctaccccacgcccc
tatgtgaggattgatggggcagtggccccagaccattggctggacccaagcattgtgtgg
gaggtgaagtgtgctgatctttccctgtcccccatctaccctgctgcacggggcctggtg
gacaaagaaaaagggatctctcttcgttttcctcggttcattcgtgtccgtaaagacaag
cagccagagcaggccactaccagtaaccaggttgcctctttgtaccggaagcagagtcag
attcagaaccaacaaagctcagacttggactccgacgttgaagactattaa

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