KEGG   Mus musculus (mouse): 17164Help
Entry
17164             CDS       T01002                                 

Gene name
Mapkapk2, AA960234, MAPKAP-K2, MK-2, MK2, Rps6kc1
Definition
(RefSeq) MAP kinase-activated protein kinase 2
  KO
K04443  mitogen-activated protein kinase-activated protein kinase 2 [EC:2.7.11.1]
Organism
mmu  Mus musculus (mouse)
Pathway
mmu04010  MAPK signaling pathway
mmu04218  Cellular senescence
mmu04370  VEGF signaling pathway
mmu04625  C-type lectin receptor signaling pathway
mmu04722  Neurotrophin signaling pathway
mmu05167  Kaposi sarcoma-associated herpesvirus infection
mmu05203  Viral carcinogenesis
Brite
KEGG Orthology (KO) [BR:mmu00001]
 09130 Environmental Information Processing
  09132 Signal transduction
   04010 MAPK signaling pathway
    17164 (Mapkapk2)
   04370 VEGF signaling pathway
    17164 (Mapkapk2)
 09140 Cellular Processes
  09143 Cell growth and death
   04218 Cellular senescence
    17164 (Mapkapk2)
 09150 Organismal Systems
  09151 Immune system
   04625 C-type lectin receptor signaling pathway
    17164 (Mapkapk2)
  09156 Nervous system
   04722 Neurotrophin signaling pathway
    17164 (Mapkapk2)
 09160 Human Diseases
  09161 Cancer: overview
   05203 Viral carcinogenesis
    17164 (Mapkapk2)
  09172 Infectious disease: viral
   05167 Kaposi sarcoma-associated herpesvirus infection
    17164 (Mapkapk2)
 09180 Brite Hierarchies
  09181 Protein families: metabolism
   01001 Protein kinases [BR:mmu01001]
    17164 (Mapkapk2)
Enzymes [BR:mmu01000]
 2. Transferases
  2.7  Transferring phosphorus-containing groups
   2.7.11  Protein-serine/threonine kinases
    2.7.11.1  non-specific serine/threonine protein kinase
     17164 (Mapkapk2)
Protein kinases [BR:mmu01001]
 Serine/threonine kinases: CAMK group
  MAPKAPK family [OT]
   17164 (Mapkapk2)
BRITE hierarchy
SSDB OrthologParalogGFIT
Motif
Pfam: Pkinase Pkinase_Tyr Kdo Kinase-like Rep_trans Choline_kinase
Motif
Other DBs
NCBI-GeneID: 17164
NCBI-ProteinID: NP_032577
MGI: 109298
Ensembl: ENSMUSG00000016528
Vega: OTTMUSG00000049116
UniProt: P49138 Q3U2P8
Position
1; 1 E4
AA seq 386 aa AA seqDB search
MLSGSPGQTPPAPFPSPPPPAPAQPPPPFPQFHVKSGLQIRKNAITDDYKVTSQVLGLGI
NGKVLRIFDKRTQQKFALKMLQDCPKARREVELHWRASQCPHIVHIVDVYENLYAGRKCL
LIVMECLDGGELFSRIQDRGDQAFTEREASEIMKSIGEAIQYLHSINIAHRDVKPENLLY
TSKRPNAILKLTDFGFAKETTSHNSLTTPCYTPYYVAPEVLGPEKYDKSCDMWSLGVIMY
ILLCGYPPFYSNHGLAISPGMKTRIRMGQYEFPNPEWSEVSEEVKMLIRNLLKTEPTQRM
TITEFMNHPWIMQSTKVPQTPLHTSRVLKEDKERWEDVKEEMTSALATMRVDYEQIKIKK
IEDASNPLLLKRRKKARAVEDAALAH
NT seq 1161 nt NT seq  +upstreamnt  +downstreamnt
atgctgtcgggctctccgggccagactccgccggcgcctttccccagccctccaccgcca
gccccggcccagccgccgccgccgttcccccagttccacgtcaagtcgggcctgcagatc
cgaaagaacgccatcaccgacgactacaaggtcaccagccaagtgcttggcctgggcatc
aacgggaaggtgctgcggatcttcgacaagagaacccagcaaaaattcgccctaaagatg
ctccaggactgtccgaaggcgcgcagagaggtggagctgcactggagggcctcccagtgc
ccacacattgtgcacatcgtggatgtctatgagaacctgtatgccgggaggaagtgcctg
ctgattgtcatggagtgtctcgatggtggagagctctttagtcgaatccaggaccgagga
gaccaggcattcacagaaagagaggcgtcagagatcatgaagagcatcggcgaggccatc
cagtacctgcactcgatcaacattgctcaccgggatgtcaagcctgagaacctcttatat
acttccaaaaggcccaatgccattttgaaactcactgattttggctttgccaaggaaacc
accagtcacaactctttgaccactccgtgttatacaccatactatgtggctccggaagtc
ctgggcccggagaagtatgacaagtcctgtgacatgtggtccttgggtgtcatcatgtat
attttgctgtgtgggtatccccccttctattccaatcacggccttgccatctctccgggc
atgaagactcgtattcgaatgggccagtatgaatttcctaacccggagtggtcagaagta
tcagaagaagtgaagatgcttatccggaatctgctaaaaacagagcccacccagagaatg
accatcacagaattcatgaaccacccctggatcatgcaatctacgaaggtccctcagact
ccactgcacaccagccgtgtcctgaaggaggacaaggaacgatgggaggatgtcaaggag
gagatgaccagtgccttggccacgatgcgtgttgactatgagcagatcaagataaagaag
atagaagacgcatccaaccctctgcttctcaagaggcggaagaaagctcgtgctgtggag
gatgcggctctcgcccactga

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